iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132544

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-specific peptidase 42

Genbank Nucleotide ID

AAMC01007077

Gene Name

usp42

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000024065.3	ENSXETT00000051907.2	ENSXETP00000051907.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-83	281.4	105	404

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           Gl+NlgNtC++NSvLQcL+ + +l ++l + +++e+++     +++ ++++ +q+ ++  ++++ ++++p+++++ l++++++f+  +q
   Q: 105  GLQNLGNTCFVNSVLQCLTYTAPLSNYLISrEHSETCH-----SQDFCMMCVMQTHISMALSNSGGVIKPSAVVNDLRRISKNFRYGSQ 188
           9*****************************44555554.....4579**********9999**************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da+Efl++ +d++++++                  l  + + + +++ ++li+++F+g l+s+++cl+c+ vs ++++ ldl+l++++
   Q: 189  EDAHEFLRYTVDEMQKSC------------------LRGSCRLDRHTQATTLIHQVFGGYLRSRVTCLSCKAVSDTYDQYLDLTLEIKM 259
           ******************..................334456678999***************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
            +     s++++Le+f+++e+l+g+n+y+c+kck+ ++a+k++++++ ++vL+l LkRf    +  +  k++k++++p+ Ldl+p++++
   Q: 260  AH-----SVNQALEQFVRPEQLDGDNAYKCSKCKQMVTASKRFTIHRTSNVLTLSLKRF----ASFNGGKLSKEIKYPEYLDLRPYTSD 339
           **.....9***************************************************....446678******************** PP
   S: 268  peekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
           p+ +   +++Y L+av++H+G s+++GHY++yvk  +++W+l++Ds+V++++  +vl+   ++aY+lfY r
   Q: 340  PNGE---PVIYVLYAVLIHTGfSCHGGHYYCYVKACNDQWYLMNDSTVSTTDIRTVLN---QQAYLLFYVR 404
           9977...9**************************************************...********87 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MTIIDKVSSA PDACQNQLCS TVAPSSGEME NGSSVWGVVS ALAKIGLGLV PAAAVYSSSS 60
VPEKPVPSEQ NDLQPGDGID PPEKILFPPA KICLKWQRVQ KVGAGLQNLG NTCFVNSVLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTATAA TAGATAAAGT GTCTTCGGCA CCTGATGCTT GCCAGAACCA ACTGTGCAGC 60
ACAGTGGCAC CCTCATCAGG AGAAATGGAA AATGGATCTT CAGTTTGGGG TGTTGTATCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001055	Aegilops tauschii	42.86	2.00e-69	257.00
IUUC-Apl-003459	Anas platyrhynchos	48.96	3.00e-145	509.00
IUUC-Aca-004440	Anolis carolinensis	59.39	0.00e+00	694.00
IUUC-Aly-006389	Arabidopsis lyrata	41.27	4.00e-77	282.00
IUUC-Ath-006710	Arabidopsis thaliana	42.72	1.00e-76	281.00
IUUC-Ame-011358	Astyanax mexicanus	62.02	5.00e-161	561.00
IUUC-Bta-012803	Bos taurus	55.85	3.00e-179	622.00
IUUC-Bdi-014036	Brachypodium distachyon	44.34	3.00e-80	293.00
IUUC-Bol-015996	Brassica oleracea	44.19	6.00e-82	298.00
IUUC-Bra-016634	Brassica rapa	43.53	2.00e-82	300.00
IUUC-Cja-019199	Callithrix jacchus	58.27	0.00e+00	645.00
IUUC-Cfa-020597	Canis familiaris	58.24	0.00e+00	635.00
IUUC-Cpo-021945	Cavia porcellus	58.17	0.00e+00	649.00
IUUC-Csa-023485	Chlorocebus sabaeus	58.08	0.00e+00	640.00
IUUC-Cho-024575	Choloepus hoffmanni	54.45	4.00e-128	452.00
IUUC-Cne-027049	Cryptococcus neoformans	34.07	5.00e-39	155.00
IUUC-Dre-028442	Danio rerio	53.92	8.00e-161	561.00
IUUC-Dno-029673	Dasypus novemcinctus	57.44	0.00e+00	664.00
IUUC-Dme-032119	Drosophila melanogaster	36.53	3.00e-59	223.00
IUUC-Ete-033088	Echinops telfairi	67.68	3.00e-144	506.00
IUUC-Eca-033579	Equus caballus	57.19	0.00e+00	638.00
IUUC-Eeu-034511	Erinaceus europaeus	38.95	8.00e-77	282.00
IUUC-Fca-035792	Felis catus	56.80	4.00e-179	622.00
IUUC-Fal-037075	Ficedula albicollis	52.02	4.00e-161	562.00
IUUC-Gga-040504	Gallus gallus	49.32	4.00e-156	545.00
IUUC-Gma-044075	Glycine max	47.60	7.00e-85	308.00
IUUC-Ggo-044798	Gorilla gorilla	54.30	1.00e-151	530.00
IUUC-Hsa-046072	Homo sapiens	57.92	0.00e+00	636.00
IUUC-Hvu-047620	Hordeum vulgare	42.59	9.00e-72	265.00
IUUC-Itr-048078	Ictidomys tridecemlineatus	58.16	0.00e+00	691.00
IUUC-Lch-049867	Latimeria chalumnae	58.52	0.00e+00	692.00
IUUC-Loc-052621	Lepisosteus oculatus	62.01	2.00e-157	550.00
IUUC-Laf-054330	Loxodonta africana	58.85	0.00e+00	652.00
IUUC-Mtr-058537	Medicago truncatula	44.97	5.00e-84	305.00
IUUC-Mla-059049	Melampsora laricipopulina	40.68	1.00e-59	224.00
IUUC-Mga-059501	Meleagris gallopavo	47.68	6.00e-140	492.00
IUUC-Mvi-060547	Microbotryum violaceum	45.15	2.00e-80	293.00
IUUC-Mmr-060864	Microcebus murinus	57.21	0.00e+00	671.00
IUUC-Mdo-062395	Monodelphis domestica	60.19	0.00e+00	716.00
IUUC-Mmu-064236	Mus musculus	58.09	0.00e+00	635.00
IUUC-Mac-064815	Musa acuminata	41.50	1.00e-84	307.00
IUUC-Mpu-065822	Mustela putorius furo	58.01	0.00e+00	665.00
IUUC-Mlu-067091	Myotis lucifugus	57.76	8.00e-180	624.00
IUUC-Nle-069004	Nomascus leucogenys	58.15	0.00e+00	638.00
IUUC-Opr-071170	Ochotona princeps	54.85	1.00e-131	464.00
IUUC-Ont-071832	Oreochromis niloticus	57.76	1.00e-155	544.00
IUUC-Oan-073711	Ornithorhynchus anatinus	58.35	0.00e+00	636.00
IUUC-Ocu-074596	Oryctolagus cuniculus	60.98	0.00e+00	632.00
IUUC-Oba-075866	Oryza barthii	42.60	1.00e-79	291.00
IUUC-Obr-076408	Oryza brachyantha	42.12	8.00e-79	288.00
IUUC-Ogl-077239	Oryza glaberrima	42.51	2.00e-80	293.00
IUUC-Ogu-078064	Oryza glumaepatula	42.51	2.00e-80	293.00
IUUC-Oin-079157	Oryza indica	42.51	2.00e-80	293.00
IUUC-Olo-080250	Oryza longistaminata	42.47	3.00e-72	266.00
IUUC-Ome-081746	Oryza meridionalis	44.16	1.00e-79	291.00
IUUC-Oni-082339	Oryza nivara	42.51	2.00e-80	293.00
IUUC-Opu-083194	Oryza punctata	43.69	2.00e-79	291.00
IUUC-Oru-085083	Oryza rufipogon	42.51	2.00e-80	293.00
IUUC-Osa-086180	Oryza sativa	42.51	2.00e-80	293.00
IUUC-Olu-087773	Ostreococcus lucimarinus	44.69	1.00e-73	269.00
IUUC-Oga-088641	Otolemur garnettii	58.15	0.00e+00	633.00
IUUC-Oar-089760	Ovis aries	55.86	6.00e-176	611.00
IUUC-Ptr-091445	Pan troglodytes	57.76	0.00e+00	636.00
IUUC-Pan-092484	Papio anubis	57.92	0.00e+00	638.00
IUUC-Psi-093277	Pelodiscus sinensis	58.27	0.00e+00	671.00
IUUC-Ppa-095853	Physcomitrella patens	48.16	2.00e-93	337.00
IUUC-Pfo-096469	Poecilia formosa	61.48	2.00e-152	533.00
IUUC-Pab-097794	Pongo abelii	58.93	5.00e-174	605.00
IUUC-Pop-099693	Populus trichocarpa	44.14	5.00e-82	299.00
IUUC-Ppe-101678	Prunus persica	44.14	4.00e-81	296.00
IUUC-Pva-103238	Pteropus vampyrus	52.72	3.00e-158	552.00
IUUC-Pgr-103270	Puccinia graminis	43.21	4.00e-69	255.00
IUUC-Ptt-103887	Puccinia triticina	41.95	4.00e-69	255.00
IUUC-Rno-105068	Rattus norvegicus	57.85	0.00e+00	650.00
IUUC-Sha-106713	Sarcophilus harrisii	60.35	0.00e+00	724.00
IUUC-Spo-108119	Schizosaccharomyces pombe	45.17	2.00e-83	302.00
IUUC-Smo-108763	Selaginella moellendorffii	46.75	4.00e-81	294.00
IUUC-Sit-109895	Setaria italica	43.45	4.00e-82	299.00
IUUC-Sly-111722	Solanum lycopersicum	46.23	2.00e-79	290.00
IUUC-Stu-112912	Solanum tuberosum	45.91	2.00e-78	287.00
IUUC-Sar-113340	Sorex araneus	56.46	5.00e-178	618.00
IUUC-Sbi-114477	Sorghum bicolor	42.61	3.00e-82	300.00
IUUC-Tgu-117149	Taeniopygia guttata	51.93	7.00e-162	564.00
IUUC-Tru-117776	Takifugu rubripes	67.49	2.00e-150	526.00
IUUC-Tsy-118974	Tarsius syrichta	67.70	2.00e-180	626.00
IUUC-Tni-120774	Tetraodon nigroviridis	70.48	5.00e-146	510.00
IUUC-Tca-120936	Theobroma cacao	43.75	5.00e-84	305.00
IUUC-Tae-122827	Triticum aestivum	43.67	3.00e-82	300.00
IUUC-Ttr-128764	Tursiops truncatus	53.41	4.00e-148	519.00
IUUC-Vvi-131535	Vitis vinifera	45.35	8.00e-87	315.00
IUUC-Xma-133131	Xiphophorus maculatus	52.36	7.00e-154	537.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence