iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049821

Ensembl Protein ID

ENSLACP00000003556.1

UniProt Accession

H3A1N5; H3A1N5_LATCH

Genbank Protein ID

ENSLACP00000003556

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01004693

Gene Name

TRAF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000003168.1	ENSLACT00000003588.1	ENSLACP00000003556.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.50e-06	26.8	75	113
E3 activity/RING/U-box	5.90e-08	32.9	72	132

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlC 45
           C+iCl  +++  + +pCgH f++ C+ + +          ++CP++
   Q: 75   CPICLMALRE-AVQTPCGHRFCRACItKSL------RDAGQKCPVD 113
           ********88.888***********95555......899999**97 PP

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrli 65
            + CpI l   r+ v +p+G+ + r++I k l++ g++cPv+++ l e++l P ++ +r i
   Q: 72   KYECPICLMALREAVQTPCGHRFCRACITKSLRDAGQKCPVDNEILLESQLFPDNFAKREI 132
           688*****************************999999*****************999977 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MSLLEMDSSS EVDSCESKCC SSMACANSIG AKEDSMGGCC AGGATAAACF HNSLSEETQG 60
YDVEFDPPLE NKYECPICLM ALREAVQTPC GHRFCRACIT KSLRDAGQKC PVDNEILLES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGAACCGAAC CCGAAACACG GAGTACAGCC GGTCCGGGAC TCGGGACTCG CAACCCGGCA 60
CGGACAGAGA GGTGAGGGGG GCAGAGGCAT AGAGACCGGG AGGAAGGGGG GACCAGAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027139--TRAF6
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0042981--P:regulation of apoptotic process
GO:0009617--P:response to bacterium
GO:0009615--P:response to virus
GO:0007165--P:signal transduction

KEGG

lcm:102353931

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000797	Aegilops tauschii	29.10	3.00e-07	49.30
IUUC-Aml-001262	Ailuropoda melanoleuca	71.01	0.00e+00	731.00
IUUC-Apl-004062	Anas platyrhynchos	69.86	0.00e+00	788.00
IUUC-Aca-004636	Anolis carolinensis	67.98	0.00e+00	749.00
IUUC-Ame-011682	Astyanax mexicanus	58.33	5.00e-169	587.00
IUUC-Bta-012692	Bos taurus	71.65	0.00e+00	740.00
IUUC-Bci-013998	Botrytis cinerea	27.65	4.00e-13	69.30
IUUC-Bdi-014466	Brachypodium distachyon	30.17	3.00e-09	55.50
IUUC-Bol-015913	Brassica oleracea	33.66	9.00e-08	52.00
IUUC-Cja-019426	Callithrix jacchus	70.08	0.00e+00	727.00
IUUC-Cfa-020948	Canis familiaris	70.13	0.00e+00	650.00
IUUC-Cpo-021378	Cavia porcellus	70.63	0.00e+00	734.00
IUUC-Csa-024045	Chlorocebus sabaeus	70.28	0.00e+00	740.00
IUUC-Cho-024973	Choloepus hoffmanni	56.30	5.00e-71	261.00
IUUC-Csv-026300	Ciona savignyi	41.96	1.00e-45	176.00
IUUC-Dre-027557	Danio rerio	62.01	0.00e+00	635.00
IUUC-Dno-030032	Dasypus novemcinctus	65.40	3.00e-102	364.00
IUUC-Dor-030790	Dipodomys ordii	70.67	0.00e+00	733.00
IUUC-Dme-031921	Drosophila melanogaster	27.60	3.00e-42	166.00
IUUC-Ete-032952	Echinops telfairi	67.81	3.00e-139	488.00
IUUC-Eca-033924	Equus caballus	65.69	0.00e+00	649.00
IUUC-Eeu-034734	Erinaceus europaeus	62.82	0.00e+00	648.00
IUUC-Fca-036222	Felis catus	67.83	0.00e+00	677.00
IUUC-Fal-036834	Ficedula albicollis	72.71	0.00e+00	723.00
IUUC-Fox-037935	Fusarium oxysporum	31.50	1.00e-19	91.30
IUUC-Gmo-039061	Gadus morhua	66.52	1.00e-91	330.00
IUUC-Ggr-040084	Gaeumannomyces graminis	28.37	5.00e-14	72.40
IUUC-Gga-040599	Gallus gallus	71.51	0.00e+00	801.00
IUUC-Gac-041977	Gasterosteus aculeatus	59.42	1.00e-173	602.00
IUUC-Ggo-044508	Gorilla gorilla	66.99	0.00e+00	682.00
IUUC-Hsa-046349	Homo sapiens	67.08	0.00e+00	754.00
IUUC-Itr-047966	Ictidomys tridecemlineatus	66.55	0.00e+00	749.00
IUUC-Lpe-051025	Leersia perrieri	35.37	7.00e-06	44.70
IUUC-Loc-051995	Lepisosteus oculatus	66.93	0.00e+00	668.00
IUUC-Laf-054115	Loxodonta africana	68.50	0.00e+00	710.00
IUUC-Mcc-055298	Macaca mulatta	70.08	0.00e+00	736.00
IUUC-Mor-057263	Magnaporthe oryzae	32.14	3.00e-17	83.20
IUUC-Mpo-057517	Magnaporthe poae	29.41	1.00e-14	74.30
IUUC-Mga-059340	Meleagris gallopavo	70.79	0.00e+00	778.00
IUUC-Mvi-060553	Microbotryum violaceum	29.76	3.00e-16	79.70
IUUC-Mmr-061063	Microcebus murinus	71.63	0.00e+00	743.00
IUUC-Mdo-062075	Monodelphis domestica	68.52	0.00e+00	759.00
IUUC-Mmu-063780	Mus musculus	69.44	0.00e+00	721.00
IUUC-Mpu-065748	Mustela putorius furo	67.62	0.00e+00	729.00
IUUC-Mlu-067888	Myotis lucifugus	69.69	0.00e+00	738.00
IUUC-Nle-069234	Nomascus leucogenys	70.47	0.00e+00	739.00
IUUC-Opr-070393	Ochotona princeps	78.40	7.00e-101	360.00
IUUC-Ont-072459	Oreochromis niloticus	60.12	9.00e-178	616.00
IUUC-Oan-073578	Ornithorhynchus anatinus	68.87	0.00e+00	760.00
IUUC-Ocu-074201	Oryctolagus cuniculus	70.28	0.00e+00	742.00
IUUC-Obr-076500	Oryza brachyantha	33.96	1.00e-07	50.10
IUUC-Olo-080508	Oryza longistaminata	33.01	1.00e-07	50.80
IUUC-Oni-083040	Oryza nivara	33.66	2.00e-06	45.80
IUUC-Opu-083468	Oryza punctata	32.74	7.00e-08	51.20
IUUC-Osa-085740	Oryza sativa	33.66	4.00e-06	45.40
IUUC-Ola-087319	Oryzias latipes	65.91	5.00e-88	318.00
IUUC-Olu-087748	Ostreococcus lucimarinus	29.46	6.00e-08	51.60
IUUC-Oga-087936	Otolemur garnettii	70.28	0.00e+00	734.00
IUUC-Oar-089379	Ovis aries	70.51	0.00e+00	741.00
IUUC-Ptr-090758	Pan troglodytes	70.47	0.00e+00	739.00
IUUC-Pan-092590	Papio anubis	70.28	0.00e+00	737.00
IUUC-Psi-093948	Pelodiscus sinensis	70.48	0.00e+00	794.00
IUUC-Pma-094434	Petromyzon marinus	47.72	5.00e-129	454.00
IUUC-Pfo-096912	Poecilia formosa	58.66	5.00e-173	600.00
IUUC-Pab-097651	Pongo abelii	70.47	0.00e+00	741.00
IUUC-Pca-100958	Procavia capensis	65.93	9.00e-158	549.00
IUUC-Pva-103247	Pteropus vampyrus	75.73	5.00e-92	331.00
IUUC-Pte-104279	Pyrenophora teres	27.57	8.00e-15	75.90
IUUC-Pyt-104429	Pyrenophora triticirepentis	27.48	6.00e-15	75.10
IUUC-Rno-104994	Rattus norvegicus	69.09	0.00e+00	721.00
IUUC-Sha-106494	Sarcophilus harrisii	69.05	0.00e+00	772.00
IUUC-Ssl-108580	Sclerotinia sclerotiorum	27.83	1.00e-13	71.20
IUUC-Sit-109710	Setaria italica	24.73	1.00e-08	53.90
IUUC-Sar-113375	Sorex araneus	70.14	0.00e+00	736.00
IUUC-Sre-115218	Sporisorium reilianum	29.95	1.00e-16	81.60
IUUC-Ssc-115417	Sus scrofa	72.39	0.00e+00	748.00
IUUC-Tgu-117232	Taeniopygia guttata	73.43	0.00e+00	774.00
IUUC-Tru-118321	Takifugu rubripes	58.38	7.00e-171	593.00
IUUC-Tni-120475	Tetraodon nigroviridis	58.20	2.00e-170	592.00
IUUC-Tbe-127719	Tupaia belangeri	58.09	2.00e-174	605.00
IUUC-Ttr-129264	Tursiops truncatus	74.76	7.00e-91	327.00
IUUC-Vpa-130244	Vicugna pacos	75.73	1.00e-91	330.00
IUUC-Vvi-131070	Vitis vinifera	30.15	3.00e-07	49.30
IUUC-Xtr-131948	Xenopus tropicalis	64.35	0.00e+00	713.00
IUUC-Xma-133132	Xiphophorus maculatus	58.66	1.00e-173	602.00
IUUC-Yli-134356	Yarrowia lipolytica	28.44	3.00e-13	69.30

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence