iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein-protein Interaction
IID	PINA
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/GAT	1.20e-28	100.0	214	302
UBD/Alpha-Helix/VHS	1.70e-51	174.1	20	152

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/GAT

   S: 38   aekikkliseleevksnvkllnemlselspegeepednellqelyetckaarpkllklieeeedndellaellkanDelnqvlnkykql 126
            e+i+kl+sele+v++nv++++eml+el+p++ ep+d ellqel++tc+a+++++l+li +  +n++l++ell++nD+ln+v+++++++
   Q: 214  PEQIGKLRSELEMVNGNVRVMSEMLTELVPTQVEPADLELLQELNRTCRAMQQRILELIPR-ISNEQLTEELLMINDNLNNVFLRHERF 301
           589**********************************************************.*************************99 PP
   S: 127  k 127
           +
   Q: 302  E 302
           7 PP

UBD/Alpha-Helix/VHS

   S: 1    atselvtsedwelileicdliqetkegakdalralrkri.nnknphvalraLtlLdscvsnCgkkfhvevaskdllee..lrell.kne 85
           at+ +++sedw+l++eicd+i+et+eg+kda+ra++kri +nkn+h++++aLt+L++cv+nCg++fhv+vas+d++e+  +r++l kn+
   Q: 20   ATDGSLQSEDWALNMEICDIINETEEGPKDAFRAVKKRIvGNKNFHEVMLALTVLETCVKNCGHRFHVLVASQDFVENvlVRTILpKNN 108
           68999*********************************99**************************************999******** PP
   S: 86   nepkvieKlkalivsWadelknepalslivaliktlkeeGlefp 129
           +++ v++K+++li+sWad+++++p+l+++va++++l+++Glefp
   Q: 109  PPTIVHDKVLNLIQSWADAFRSSPDLTGVVAVYEDLRRKGLEFP 152
           *******************************************8 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MDFLLGNPFS SPVGQRIEKA TDGSLQSEDW ALNMEICDII NETEEGPKDA FRAVKKRIVG 60
NKNFHEVMLA LTVLETCVKN CGHRFHVLVA SQDFVENVLV RTILPKNNPP TIVHDKVLNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCAGCGGG TCACGTGACG GGTCGGCGGC GCCGGCGGTT GCTGTCACCT GATTCTGGGA 60
GCTGGTGGCA GTGGTAGCCG CGGCAATGGA CTTTCTCCTG GGAAACCCGT TCAGTTCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0653--Protein transport
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR008942--ENTH_VHS
IPR004152--GAT_dom
IPR014645--TOM1
IPR002014--VHS_dom

PROSITE

PS50909--GAT
PS50179--VHS

Pfam

PF03127--GAT
PF00790--VHS

SMART

SM00288--VHS

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0016020--C:membrane
GO:0006886--P:intracellular protein transport

KEGG

rno:361370

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001372	Ailuropoda melanoleuca	86.43	0.00e+00	857.00
IUUC-Apl-004197	Anas platyrhynchos	71.43	0.00e+00	658.00
IUUC-Aca-005277	Anolis carolinensis	70.29	0.00e+00	634.00
IUUC-Bta-013410	Bos taurus	88.21	0.00e+00	864.00
IUUC-Cja-018944	Callithrix jacchus	83.17	0.00e+00	803.00
IUUC-Cfa-021024	Canis familiaris	88.01	0.00e+00	849.00
IUUC-Cpo-021418	Cavia porcellus	82.96	0.00e+00	795.00
IUUC-Csa-023653	Chlorocebus sabaeus	85.69	0.00e+00	851.00
IUUC-Dno-029610	Dasypus novemcinctus	86.06	0.00e+00	685.00
IUUC-Dor-030925	Dipodomys ordii	78.05	0.00e+00	738.00
IUUC-Eca-034207	Equus caballus	89.43	0.00e+00	855.00
IUUC-Eeu-035025	Erinaceus europaeus	73.33	4.00e-122	431.00
IUUC-Fca-036407	Felis catus	87.36	0.00e+00	799.00
IUUC-Fal-036809	Ficedula albicollis	72.76	0.00e+00	673.00
IUUC-Gga-040357	Gallus gallus	71.92	0.00e+00	706.00
IUUC-Ggo-044454	Gorilla gorilla	87.60	0.00e+00	860.00
IUUC-Hsa-046652	Homo sapiens	88.82	0.00e+00	866.00
IUUC-Itr-049028	Ictidomys tridecemlineatus	84.11	0.00e+00	846.00
IUUC-Laf-054231	Loxodonta africana	86.21	0.00e+00	663.00
IUUC-Mcc-055475	Macaca mulatta	89.02	0.00e+00	865.00
IUUC-Meu-056002	Macropus eugenii	63.55	3.00e-148	518.00
IUUC-Mla-058817	Melampsora laricipopulina	25.37	4.00e-19	89.40
IUUC-Mga-059199	Meleagris gallopavo	68.97	0.00e+00	642.00
IUUC-Mmr-061193	Microcebus murinus	88.44	0.00e+00	802.00
IUUC-Mdo-062456	Monodelphis domestica	77.95	0.00e+00	697.00
IUUC-Mmu-063746	Mus musculus	96.14	0.00e+00	971.00
IUUC-Mac-064731	Musa acuminata	32.06	7.00e-35	142.00
IUUC-Mpu-066772	Mustela putorius furo	88.03	0.00e+00	881.00
IUUC-Mlu-067475	Myotis lucifugus	83.05	0.00e+00	675.00
IUUC-Nle-068998	Nomascus leucogenys	86.03	0.00e+00	837.00
IUUC-Oan-073103	Ornithorhynchus anatinus	73.53	0.00e+00	723.00
IUUC-Ocu-073922	Oryctolagus cuniculus	81.80	0.00e+00	757.00
IUUC-Oga-089050	Otolemur garnettii	79.72	0.00e+00	769.00
IUUC-Oar-090246	Ovis aries	84.31	0.00e+00	809.00
IUUC-Ptr-090714	Pan troglodytes	88.24	0.00e+00	857.00
IUUC-Pan-092875	Papio anubis	89.02	0.00e+00	865.00
IUUC-Psi-094051	Pelodiscus sinensis	71.81	0.00e+00	687.00
IUUC-Pab-098291	Pongo abelii	87.58	0.00e+00	791.00
IUUC-Pca-100907	Procavia capensis	78.86	0.00e+00	717.00
IUUC-Pva-102610	Pteropus vampyrus	80.28	0.00e+00	774.00
IUUC-Pgr-103677	Puccinia graminis	25.53	1.00e-21	98.20
IUUC-Sha-107255	Sarcophilus harrisii	76.72	0.00e+00	686.00
IUUC-Ssl-108413	Sclerotinia sclerotiorum	39.73	2.00e-22	97.80
IUUC-Sre-115232	Sporisorium reilianum	25.38	5.00e-18	85.90
IUUC-Tgu-117517	Taeniopygia guttata	73.85	0.00e+00	712.00
IUUC-Tni-120701	Tetraodon nigroviridis	51.90	1.00e-144	506.00
IUUC-Ttr-128710	Tursiops truncatus	81.34	0.00e+00	741.00
IUUC-Uma-129380	Ustilago maydis	25.86	4.00e-15	76.30
IUUC-Vpa-130381	Vicugna pacos	69.10	2.00e-104	372.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence