iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-068122

Ensembl Protein ID

ENSMLUP00000005717.2

UniProt Accession

G1P6L6; G1P6L6_MYOLU

Genbank Protein ID

ENSMLUP00000005717

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02014932

Gene Name

FAF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000006252.2	ENSMLUT00000006262.2	ENSMLUP00000005717.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	2.60e-06	27.4	2	37
ULD/UDP/UFD/UBX	1.50e-19	70.4	561	638
ULD/UDP/UBQ/UBQ_Other	8.40e-11	41.7	103	162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 6    kleqlve.MGF.dreealqaLraannnleaAveyLl 39
           +l+ +++ +G+ + +ea++ L+++n++l aA++ ++
   Q: 2    ILADFQAcTGIeNIDEAITLLEQNNWDLVAAINGVI 37
           799*****************************9875 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfveyllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllve 80
           +++ ++l+iR+p+G++l+r+F +s++l+ +++fv+ ++++++ +F+L+s+fPrr++++ + +++l e +L+p+++l++e
   Q: 561  AEPVSKLRIRTPSGEFLERRFLASNKLQIVFDFVT-SKGFPWNEFKLLSTFPRRDITQLDPNKSLLEVKLFPQETLFLE 638
           4669*******************************.****************************************986 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL...eddktLadyglkdgstihll 70
           + ++ ++ s+tV+e+K+ +e +l ip   +++++kG      ed   L++++l+ ++ +++l
   Q: 103  NVDVVLEDSCTVGEIKQILENELQIP--VSKMLLKGWKTgdvEDSTVLKSLHLPKNNSLYVL 162
           5566678999****************..55899997776777***************99987 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MILADFQACT GIENIDEAIT LLEQNNWDLV AAINGVIPQE NGILQSDYGS ETISGPAFDP 60
ASHPAPAPAP SSSSAFRPVM PSRQIVERQP RMLDFRVEYR DRNVDVVLED SCTVGEIKQI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGGCGCGC TCGCTCCCGG AGCCGCGAAC TCGGCGGCCG CTATGGCGTC AAACATGGAC 60
CGGGAGATGA TTCTGGCGGA TTTTCAGGTG AAGCGTCTGG CCCTTGTCCC CCTGCCACCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033043--FAF1_UBX
IPR012336--Thioredoxin-like_fold
IPR006577--UAS
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50033--UBX

Pfam

PF00789--UBX

SMART

SM00594--UAS
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0005635--C:nuclear envelope
GO:0048471--C:perinuclear region of cytoplasm
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0008219--P:cell death
GO:0007253--P:cytoplasmic sequestering of NF-kappaB
GO:1902043--P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:0031334--P:positive regulation of protein complex assembly
GO:0030155--P:regulation of cell adhesion
GO:0042176--P:regulation of protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002153	Ailuropoda melanoleuca	97.04	0.00e+00	1188.00
IUUC-Apl-004127	Anas platyrhynchos	89.66	0.00e+00	1116.00
IUUC-Aca-005188	Anolis carolinensis	88.85	0.00e+00	1107.00
IUUC-Ame-010696	Astyanax mexicanus	75.97	0.00e+00	848.00
IUUC-Bta-012965	Bos taurus	97.66	0.00e+00	1204.00
IUUC-Cel-018420	Caenorhabditis elegans	29.41	1.00e-29	124.00
IUUC-Cja-019128	Callithrix jacchus	95.50	0.00e+00	1192.00
IUUC-Cfa-021201	Canis familiaris	95.21	0.00e+00	892.00
IUUC-Cpo-021475	Cavia porcellus	95.39	0.00e+00	899.00
IUUC-Csa-024076	Chlorocebus sabaeus	96.11	0.00e+00	1188.00
IUUC-Cho-025067	Choloepus hoffmanni	82.87	0.00e+00	1033.00
IUUC-Cin-025663	Ciona intestinalis	44.35	1.00e-69	256.00
IUUC-Csv-025894	Ciona savignyi	34.51	8.00e-69	254.00
IUUC-Dre-027508	Danio rerio	74.89	0.00e+00	927.00
IUUC-Dno-029336	Dasypus novemcinctus	95.79	0.00e+00	1176.00
IUUC-Dor-030218	Dipodomys ordii	88.32	0.00e+00	1063.00
IUUC-Dme-031581	Drosophila melanogaster	34.05	3.00e-93	336.00
IUUC-Ete-032860	Echinops telfairi	75.78	0.00e+00	676.00
IUUC-Eca-034321	Equus caballus	97.16	0.00e+00	1043.00
IUUC-Eeu-034844	Erinaceus europaeus	74.38	1.00e-139	489.00
IUUC-Fca-036575	Felis catus	97.07	0.00e+00	717.00
IUUC-Fal-037128	Ficedula albicollis	90.05	0.00e+00	1125.00
IUUC-Gmo-038694	Gadus morhua	74.50	0.00e+00	889.00
IUUC-Gga-040826	Gallus gallus	90.05	0.00e+00	1126.00
IUUC-Gac-042125	Gasterosteus aculeatus	75.00	0.00e+00	951.00
IUUC-Ggo-045254	Gorilla gorilla	96.57	0.00e+00	1197.00
IUUC-Hsa-046722	Homo sapiens	96.42	0.00e+00	1196.00
IUUC-Hvu-047478	Hordeum vulgare	37.93	3.00e-08	53.50
IUUC-Itr-048149	Ictidomys tridecemlineatus	97.13	2.00e-102	363.00
IUUC-Lch-050312	Latimeria chalumnae	81.29	0.00e+00	673.00
IUUC-Loc-051990	Lepisosteus oculatus	77.35	0.00e+00	951.00
IUUC-Laf-054375	Loxodonta africana	96.29	0.00e+00	714.00
IUUC-Mcc-054627	Macaca mulatta	96.23	0.00e+00	1180.00
IUUC-Meu-056611	Macropus eugenii	71.94	1.00e-127	449.00
IUUC-Mga-059400	Meleagris gallopavo	88.79	0.00e+00	1112.00
IUUC-Mmr-060882	Microcebus murinus	95.95	0.00e+00	1155.00
IUUC-Mdo-061874	Monodelphis domestica	90.97	0.00e+00	1152.00
IUUC-Mmu-063444	Mus musculus	95.48	0.00e+00	1183.00
IUUC-Mpu-065713	Mustela putorius furo	95.12	0.00e+00	1164.00
IUUC-Nle-069025	Nomascus leucogenys	96.11	0.00e+00	1186.00
IUUC-Opr-071089	Ochotona princeps	85.67	0.00e+00	1074.00
IUUC-Ont-072421	Oreochromis niloticus	74.62	0.00e+00	935.00
IUUC-Oan-073092	Ornithorhynchus anatinus	88.27	0.00e+00	850.00
IUUC-Ola-086497	Oryzias latipes	75.95	0.00e+00	946.00
IUUC-Oga-088854	Otolemur garnettii	94.24	0.00e+00	1180.00
IUUC-Oar-090120	Ovis aries	97.66	0.00e+00	1178.00
IUUC-Ptr-091554	Pan troglodytes	96.57	0.00e+00	1197.00
IUUC-Pan-091985	Papio anubis	96.26	0.00e+00	1167.00
IUUC-Psi-093548	Pelodiscus sinensis	90.25	0.00e+00	1079.00
IUUC-Pma-094123	Petromyzon marinus	52.24	2.00e-52	198.00
IUUC-Pfo-096729	Poecilia formosa	74.85	0.00e+00	938.00
IUUC-Pab-097810	Pongo abelii	96.73	0.00e+00	1199.00
IUUC-Pca-101079	Procavia capensis	88.61	0.00e+00	887.00
IUUC-Pva-102534	Pteropus vampyrus	89.45	0.00e+00	904.00
IUUC-Rno-105127	Rattus norvegicus	93.81	0.00e+00	1087.00
IUUC-Sha-106667	Sarcophilus harrisii	92.74	0.00e+00	1027.00
IUUC-Ssl-108656	Sclerotinia sclerotiorum	23.88	2.50e-02	32.30
IUUC-Sar-113424	Sorex araneus	82.33	0.00e+00	652.00
IUUC-Ssc-115974	Sus scrofa	97.01	0.00e+00	1157.00
IUUC-Tgu-116495	Taeniopygia guttata	90.05	0.00e+00	1127.00
IUUC-Tru-118727	Takifugu rubripes	73.41	0.00e+00	916.00
IUUC-Tsy-118906	Tarsius syrichta	90.81	0.00e+00	1065.00
IUUC-Tni-119717	Tetraodon nigroviridis	75.85	0.00e+00	936.00
IUUC-Tur-126134	Triticum urartu	40.91	5.00e-08	53.10
IUUC-Tbe-127849	Tupaia belangeri	82.39	0.00e+00	702.00
IUUC-Ttr-128660	Tursiops truncatus	92.86	0.00e+00	1127.00
IUUC-Vpa-130359	Vicugna pacos	97.01	0.00e+00	1183.00
IUUC-Xtr-132212	Xenopus tropicalis	87.07	0.00e+00	719.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence