iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-008001

Ensembl Protein ID

AAS53529

UniProt Accession

Q754B2; Q754B2_ASHGO

Genbank Protein ID

AAS53529.2

Protein Name

AFR158Wp

Genbank Nucleotide ID

AE016819

Gene Name

AGOS_AFR158W

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_AFR158W	AAS53529	AAS53529

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Other/Other	71.12	0.00e+00	1040.00	IUUC-Hsa-046162
UBD/Other/Other	88.54	0.00e+00	1332.00	IUUC-Sce-106244

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ashbya gossypii

Protein Sequence
(Fasta)

MVKDEHKRLL DASGTEPRDE DATATAILKR KKKDNYLLVD DAVKDDNSVI VVNSNTMDLL 60
QLFRGDTVLV KGKMRKDTVL IVLLDDELAD GVCRINRVVR NNLRVRLGDL VSIHPCPDIK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTCAAGG ACGAGCACAA GCGGTTGTTG GATGCGTCGG GTACGGAGCC TCGGGACGAG 60
GACGCCACCG CGACGGCGAT CTTGAAGCGC AAGAAGAAGG ACAACTACTT GCTAGTGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR003593--AAA+_ATPase
IPR005938--AAA_ATPase_CDC48
IPR009010--Asp_de-COase-like_dom
IPR003959--ATPase_AAA_core
IPR003960--ATPase_AAA_CS
IPR004201--Cdc48_dom2
IPR029067--CDC48_domain_2-like
IPR003338--CDC4_N-term_subdom
IPR027417--P-loop_NTPase
IPR015415--Vps4_C

PROSITE

PS00674--AAA

Pfam

PF00004--AAA
PF02933--CDC48_2
PF02359--CDC48_N
PF09336--Vps4_C

SMART

SM00382--AAA
SM01072--CDC48_2
SM01073--CDC48_N

Gene Ontology

GO:0036266--C:Cdc48p-Npl4p-Vms1p AAA ATPase complex
GO:0022625--C:cytosolic large ribosomal subunit
GO:0000837--C:Doa10p ubiquitin ligase complex
GO:0000839--C:Hrd1p ubiquitin ligase ERAD-L complex
GO:1990023--C:mitotic spindle midzone
GO:0000790--C:nuclear chromatin
GO:1990112--C:RQC complex
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0019888--F:protein phosphatase regulator activity
GO:0046034--P:ATP metabolic process
GO:0016320--P:endoplasmic reticulum membrane fusion
GO:0071712--P:ER-associated misfolded protein catabolic process
GO:0061166--P:establishment of endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site
GO:0072671--P:mitochondria-associated ubiquitin-dependent protein catabolic process
GO:0051306--P:mitotic sister chromatid separation
GO:0051228--P:mitotic spindle disassembly
GO:0051974--P:negative regulation of telomerase activity
GO:0070651--P:nonfunctional rRNA decay
GO:0034727--P:piecemeal microautophagy of nucleus
GO:2001168--P:positive regulation of histone H2B ubiquitination
GO:1900182--P:positive regulation of protein localization to nucleus
GO:0016485--P:protein processing
GO:0030970--P:retrograde protein transport, ER to cytosol
GO:0034517--P:ribophagy
GO:1990116--P:ribosome-associated ubiquitin-dependent protein catabolic process
GO:1990171--P:SCF complex disassembly in response to cadmium stress
GO:0031134--P:sister chromatid biorientation
GO:0071629--P:ubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
GO:0071630--P:ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

ago:AGOS_AFR158W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000524	Aegilops tauschii	67.56	0.00e+00	1057.00
IUUC-Aml-001849	Ailuropoda melanoleuca	71.48	0.00e+00	1100.00
IUUC-Atr-002619	Amborella trichopoda	66.75	0.00e+00	1113.00
IUUC-Apl-004070	Anas platyrhynchos	71.43	0.00e+00	1093.00
IUUC-Aca-004847	Anolis carolinensis	71.05	0.00e+00	1098.00
IUUC-Aly-005406	Arabidopsis lyrata	67.17	0.00e+00	1109.00
IUUC-Ath-006796	Arabidopsis thaliana	68.25	0.00e+00	1105.00
IUUC-Acl-008066	Aspergillus clavatus	76.74	0.00e+00	1170.00
IUUC-Afl-008505	Aspergillus flavus	75.72	0.00e+00	1186.00
IUUC-Afu-008840	Aspergillus fumigatus	77.63	0.00e+00	1195.00
IUUC-Ani-009368	Aspergillus nidulans	74.69	0.00e+00	1195.00
IUUC-Ang-009724	Aspergillus niger	76.30	0.00e+00	1184.00
IUUC-Aor-010204	Aspergillus oryzae	75.72	0.00e+00	1186.00
IUUC-Ate-010370	Aspergillus terreus	75.94	0.00e+00	1180.00
IUUC-Ame-011388	Astyanax mexicanus	71.54	0.00e+00	1087.00
IUUC-Bgr-012223	Blumeria graminis	75.12	0.00e+00	1219.00
IUUC-Bta-013188	Bos taurus	71.05	0.00e+00	1102.00
IUUC-Bci-013831	Botrytis cinerea	76.45	0.00e+00	1177.00
IUUC-Bdi-014967	Brachypodium distachyon	68.60	0.00e+00	1099.00
IUUC-Bol-016113	Brassica oleracea	67.49	0.00e+00	1108.00
IUUC-Bra-017796	Brassica rapa	67.45	0.00e+00	1110.00
IUUC-Cel-018243	Caenorhabditis elegans	68.14	0.00e+00	1071.00
IUUC-Cja-019904	Callithrix jacchus	70.66	0.00e+00	1082.00
IUUC-Cfa-020304	Canis familiaris	71.05	0.00e+00	1102.00
IUUC-Cpo-021518	Cavia porcellus	71.61	0.00e+00	1097.00
IUUC-Cre-022719	Chlamydomonas reinhardtii	68.35	0.00e+00	1096.00
IUUC-Csa-023444	Chlorocebus sabaeus	71.17	0.00e+00	1098.00
IUUC-Cho-024482	Choloepus hoffmanni	70.58	0.00e+00	1071.00
IUUC-Cin-025517	Ciona intestinalis	69.58	0.00e+00	1082.00
IUUC-Csv-026060	Ciona savignyi	70.31	0.00e+00	1121.00
IUUC-Cgl-026690	Colletotrichum gloeosporioides	74.30	0.00e+00	1204.00
IUUC-Cne-026910	Cryptococcus neoformans	70.11	0.00e+00	1142.00
IUUC-Cme-027145	Cyanidioschyzon merolae	68.22	0.00e+00	1072.00
IUUC-Dre-028487	Danio rerio	71.28	0.00e+00	1085.00
IUUC-Dno-029257	Dasypus novemcinctus	71.17	0.00e+00	1098.00
IUUC-Dor-030473	Dipodomys ordii	69.68	0.00e+00	1057.00
IUUC-Dse-031319	Dothistroma septosporum	76.33	0.00e+00	1171.00
IUUC-Dme-032203	Drosophila melanogaster	68.77	0.00e+00	1070.00
IUUC-Eca-033311	Equus caballus	71.10	0.00e+00	1097.00
IUUC-Eeu-035293	Erinaceus europaeus	75.06	2.00e-174	603.00
IUUC-Fca-036097	Felis catus	72.86	0.00e+00	1065.00
IUUC-Fal-037292	Ficedula albicollis	71.61	0.00e+00	1099.00
IUUC-Fox-037827	Fusarium oxysporum	77.10	0.00e+00	1213.00
IUUC-Fso-038226	Fusarium solani	76.88	0.00e+00	1221.00
IUUC-Gmo-039157	Gadus morhua	66.10	0.00e+00	985.00
IUUC-Ggr-039951	Gaeumannomyces graminis	76.90	0.00e+00	1193.00
IUUC-Gga-041183	Gallus gallus	71.17	0.00e+00	1100.00
IUUC-Gac-042039	Gasterosteus aculeatus	69.39	0.00e+00	1077.00
IUUC-Gma-044090	Glycine max	65.66	0.00e+00	1092.00
IUUC-Ggo-045568	Gorilla gorilla	71.17	0.00e+00	1098.00
IUUC-Hsa-046162	Homo sapiens	71.17	0.00e+00	1098.00
IUUC-Hvu-047107	Hordeum vulgare	71.34	0.00e+00	899.00
IUUC-Itr-047885	Ictidomys tridecemlineatus	70.99	0.00e+00	1095.00
IUUC-Kpa-049220	Komagataella pastoris	83.75	0.00e+00	1390.00
IUUC-Lch-050657	Latimeria chalumnae	71.70	0.00e+00	978.00
IUUC-Lpe-051083	Leersia perrieri	67.47	0.00e+00	1097.00
IUUC-Loc-052064	Lepisosteus oculatus	71.15	0.00e+00	1085.00
IUUC-Lma-053323	Leptosphaeria maculans	76.43	0.00e+00	1185.00
IUUC-Laf-054574	Loxodonta africana	71.61	0.00e+00	1097.00
IUUC-Mcc-055448	Macaca mulatta	71.17	0.00e+00	1098.00
IUUC-Meu-056316	Macropus eugenii	66.71	0.00e+00	995.00
IUUC-Mor-057057	Magnaporthe oryzae	76.74	0.00e+00	1186.00
IUUC-Mpo-057406	Magnaporthe poae	76.66	0.00e+00	1189.00
IUUC-Mtr-057648	Medicago truncatula	66.18	0.00e+00	1113.00
IUUC-Mla-059156	Melampsora laricipopulina	72.04	0.00e+00	1187.00
IUUC-Mga-060004	Meleagris gallopavo	68.96	0.00e+00	960.00
IUUC-Mvi-060488	Microbotryum violaceum	73.24	0.00e+00	1158.00
IUUC-Mmr-061027	Microcebus murinus	71.61	0.00e+00	1096.00
IUUC-Mdo-062159	Monodelphis domestica	71.17	0.00e+00	1100.00
IUUC-Mmu-063633	Mus musculus	71.17	0.00e+00	1098.00
IUUC-Mac-064919	Musa acuminata	66.91	0.00e+00	1104.00
IUUC-Mpu-066078	Mustela putorius furo	71.05	0.00e+00	1102.00
IUUC-Mlu-067757	Myotis lucifugus	71.05	0.00e+00	1098.00
IUUC-Nfi-068533	Neosartorya fischeri	77.38	0.00e+00	1182.00
IUUC-Ncr-068775	Neurospora crassa	77.06	0.00e+00	1161.00
IUUC-Nle-069424	Nomascus leucogenys	71.61	0.00e+00	1097.00
IUUC-Opr-071147	Ochotona princeps	71.02	0.00e+00	1081.00
IUUC-Ont-071351	Oreochromis niloticus	71.41	0.00e+00	1062.00
IUUC-Oan-073335	Ornithorhynchus anatinus	69.45	0.00e+00	1099.00
IUUC-Ocu-074072	Oryctolagus cuniculus	71.17	0.00e+00	1098.00
IUUC-Oba-075914	Oryza barthii	68.54	0.00e+00	1109.00
IUUC-Obr-076224	Oryza brachyantha	69.46	0.00e+00	1098.00
IUUC-Ogl-077282	Oryza glaberrima	68.82	0.00e+00	1115.00
IUUC-Ogu-078174	Oryza glumaepatula	68.54	0.00e+00	1109.00
IUUC-Oin-079103	Oryza indica	68.54	0.00e+00	1109.00
IUUC-Olo-080675	Oryza longistaminata	68.41	0.00e+00	1108.00
IUUC-Ome-081959	Oryza meridionalis	68.82	0.00e+00	1115.00
IUUC-Oni-082078	Oryza nivara	68.54	0.00e+00	1108.00
IUUC-Opu-083806	Oryza punctata	68.54	0.00e+00	1111.00
IUUC-Oru-084634	Oryza rufipogon	68.54	0.00e+00	1110.00
IUUC-Osa-085960	Oryza sativa	68.54	0.00e+00	1109.00
IUUC-Ola-086382	Oryzias latipes	71.47	0.00e+00	1058.00
IUUC-Olu-087839	Ostreococcus lucimarinus	67.55	0.00e+00	1068.00
IUUC-Oga-088037	Otolemur garnettii	70.79	0.00e+00	1095.00
IUUC-Oar-089684	Ovis aries	71.48	0.00e+00	1100.00
IUUC-Ptr-091378	Pan troglodytes	71.17	0.00e+00	1098.00
IUUC-Pan-092849	Papio anubis	71.17	0.00e+00	1098.00
IUUC-Psi-093725	Pelodiscus sinensis	70.44	0.00e+00	1055.00
IUUC-Pma-094537	Petromyzon marinus	67.55	3.00e-162	562.00
IUUC-Pno-094915	Phaeosphaeria nodorum	80.71	0.00e+00	1135.00
IUUC-Ppa-095632	Physcomitrella patens	67.49	0.00e+00	1071.00
IUUC-Pfo-097440	Poecilia formosa	71.28	0.00e+00	1061.00
IUUC-Pab-098469	Pongo abelii	71.17	0.00e+00	1098.00
IUUC-Pop-100047	Populus trichocarpa	67.16	0.00e+00	1100.00
IUUC-Pca-100399	Procavia capensis	67.09	0.00e+00	1007.00
IUUC-Ppe-101767	Prunus persica	66.17	0.00e+00	1104.00
IUUC-Pva-102426	Pteropus vampyrus	70.66	0.00e+00	1076.00
IUUC-Pgr-103599	Puccinia graminis	73.74	0.00e+00	1158.00
IUUC-Ptt-103740	Puccinia triticina	72.72	0.00e+00	1159.00
IUUC-Pte-104030	Pyrenophora teres	73.36	0.00e+00	1170.00
IUUC-Pyt-104541	Pyrenophora triticirepentis	73.20	0.00e+00	1165.00
IUUC-Rno-105144	Rattus norvegicus	71.17	0.00e+00	1098.00
IUUC-Sce-106244	Saccharomyces cerevisiae	87.76	0.00e+00	1344.00
IUUC-Sha-106589	Sarcophilus harrisii	71.61	0.00e+00	1098.00
IUUC-Sja-107673	Schizosaccharomyces japonicus	75.64	0.00e+00	1203.00
IUUC-Spo-108247	Schizosaccharomyces pombe	75.43	0.00e+00	1164.00
IUUC-Ssl-108642	Sclerotinia sclerotiorum	76.38	0.00e+00	1176.00
IUUC-Smo-108877	Selaginella moellendorffii	69.50	0.00e+00	1105.00
IUUC-Sit-110368	Setaria italica	66.87	0.00e+00	1100.00
IUUC-Sly-111011	Solanum lycopersicum	67.70	0.00e+00	1123.00
IUUC-Stu-112133	Solanum tuberosum	67.74	0.00e+00	1125.00
IUUC-Sar-113021	Sorex araneus	71.61	0.00e+00	1097.00
IUUC-Sbi-114462	Sorghum bicolor	68.31	0.00e+00	1103.00
IUUC-Sre-115052	Sporisorium reilianum	72.17	0.00e+00	1162.00
IUUC-Ssc-116293	Sus scrofa	70.87	0.00e+00	1097.00
IUUC-Tgu-116544	Taeniopygia guttata	68.81	0.00e+00	1019.00
IUUC-Tru-117991	Takifugu rubripes	73.05	0.00e+00	785.00
IUUC-Tsy-119131	Tarsius syrichta	75.33	3.00e-168	583.00
IUUC-Tni-120192	Tetraodon nigroviridis	70.76	0.00e+00	1055.00
IUUC-Tca-121502	Theobroma cacao	67.85	0.00e+00	1075.00
IUUC-Tre-122189	Trichoderma reesei	76.76	0.00e+00	1203.00
IUUC-Tvi-122310	Trichoderma virens	76.26	0.00e+00	1187.00
IUUC-Tae-124332	Triticum aestivum	68.43	0.00e+00	1065.00
IUUC-Tur-126733	Triticum urartu	67.91	0.00e+00	1055.00
IUUC-Tme-127147	Tuber melanosporum	76.35	0.00e+00	1163.00
IUUC-Tbe-127255	Tupaia belangeri	66.11	0.00e+00	1023.00
IUUC-Ttr-128876	Tursiops truncatus	71.23	0.00e+00	1090.00
IUUC-Uma-129448	Ustilago maydis	71.59	0.00e+00	1142.00
IUUC-Vda-129800	Verticillium dahliae	74.16	0.00e+00	1183.00
IUUC-Vpa-130573	Vicugna pacos	76.01	0.00e+00	662.00
IUUC-Vvi-131622	Vitis vinifera	69.88	0.00e+00	1106.00
IUUC-Xtr-132458	Xenopus tropicalis	72.67	0.00e+00	1063.00
IUUC-Xma-134045	Xiphophorus maculatus	71.28	0.00e+00	1061.00
IUUC-Yli-134382	Yarrowia lipolytica	83.46	0.00e+00	1315.00
IUUC-Zma-135400	Zea mays	68.31	0.00e+00	1101.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence