iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mac-065557

Ensembl Protein ID

GSMUA_Achr4P06270_001

UniProt Accession

M0SLJ4; M0SLJ4_MUSAM

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSMUA_Achr4G06270_001	GSMUA_Achr4T06270_001	GSMUA_Achr4P06270_001

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.30e-120	402.4	3145	3484

Active Site

Position(s)	Description	Evidence
3452	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrl 87
            +dlk rl v+f+gEeg+d+gG+tre+++lls+ ++++ + lf+ + ++++t+qpnp+s ++ +ehl++F+f+Grl++kal+dg+l
   Q: 3145 SQDLKGRLTVQFQGEEGIDAGGLTREWYQLLSRVTFDKGALLFT-TVGNNSTFQPNPNSAYQ-TEHLSYFRFVGRLVAKALFDGQL 3228
           689************************************99995.55677788******996.5********************** PP
   S: 88   ldlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseei...lgetkeeeLkpgGenipVtneNk 170
           ld+ +++sfyk++lg+k++++d+e+vdp++yk+lk+++en+ sdi +l++ +  +++++i    ++++++eL+pgG+ni+Vt+e k
   Q: 3229 LDVYFTRSFYKHILGVKVTYHDIEAVDPDYYKNLKWMLENDVSDIPDLTFSIDADEEKHIlygKNQVTDYELIPGGRNIRVTEETK 3314
           ****************************************7777777655555554444485555667788*************** PP
   S: 171  eeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleef 256
           +eYv+lv+e++l++ i+ q+++f eGfne++p el+s+F+ +elell++G +eid++dl+++t+y+g y++ s +iqwFwev+++f
   Q: 3315 HEYVDLVAEHILTTAIRPQINSFLEGFNELVPRELVSIFNDKELELLLSGLPEIDIDDLQANTEYTG-YSAASIVIQWFWEVVKSF 3399
           *****************************************************************66.****************** PP
   S: 257  sseerkafLqFvTgssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
           ++e+ +++LqFvTg+s++Pl+Gf++l+    p++f+i+k +++++rlPs++TCfn+L+LPeYss e+l+e+Ll+Ai+e+ +gF++
   Q: 3400 NKEDMARLLQFVTGTSKVPLEGFKALQgisgPQRFQIHKaYGTPKRLPSAHTCFNQLDLPEYSSREQLEERLLLAIHEAsEGFGF 3484
           ***************************************99999***********************************9***85 PP

Organism

Musa acuminata

Protein Sequence
(Fasta)

MTLRVLYRVS YPSHITFFIN NVISAAFENI EELLKDFRWE FDKGDFHHWI DLFNHFDSFF 60
EKHIKPRKDL QFEDNFLNAD PLFPRDAVLQ ILRVMRVILD NCTNKHFYSS FEQHLSLLLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACACTTA GAGTGCTCTA TAGGGTCTCA TATGTGATGT AAAAAATAAA TCCTTGGTCA 60
TTTCTTTTTG TTTAGTTTCT CGTTATGTAT CTATGCCTTT ATTTAATCCT TATCTTTATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS50237--HECT
PS50030--UBA

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT
PF00627--UBA

SMART

SM00119--HECTc
SM00165--UBA

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001684	Ailuropoda melanoleuca	52.09	7.00e-126	446.00
IUUC-Atr-003044	Amborella trichopoda	54.82	0.00e+00	1544.00
IUUC-Apl-003729	Anas platyrhynchos	49.31	6.00e-91	326.00
IUUC-Aca-005263	Anolis carolinensis	52.33	9.00e-127	449.00
IUUC-Aly-006083	Arabidopsis lyrata	47.73	0.00e+00	1251.00
IUUC-Ath-007472	Arabidopsis thaliana	51.36	0.00e+00	1476.00
IUUC-Afl-008712	Aspergillus flavus	41.39	1.00e-140	493.00
IUUC-Ani-009412	Aspergillus nidulans	34.15	2.00e-158	554.00
IUUC-Aor-010186	Aspergillus oryzae	40.90	2.00e-130	460.00
IUUC-Ame-011067	Astyanax mexicanus	51.85	8.00e-125	443.00
IUUC-Bta-012813	Bos taurus	52.09	7.00e-126	446.00
IUUC-Bra-016637	Brassica rapa	48.49	0.00e+00	1415.00
IUUC-Cja-018741	Callithrix jacchus	52.20	2.00e-125	444.00
IUUC-Cfa-020083	Canis familiaris	52.09	7.00e-126	446.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	61.54	2.00e-158	551.00
IUUC-Csa-023853	Chlorocebus sabaeus	52.09	6.00e-126	447.00
IUUC-Cho-024718	Choloepus hoffmanni	53.93	1.00e-116	415.00
IUUC-Dno-029680	Dasypus novemcinctus	52.09	5.00e-126	447.00
IUUC-Dor-030902	Dipodomys ordii	46.74	8.00e-107	383.00
IUUC-Eca-033915	Equus caballus	51.52	1.00e-123	439.00
IUUC-Eeu-034963	Erinaceus europaeus	51.74	5.00e-124	440.00
IUUC-Fca-035824	Felis catus	52.09	6.00e-126	446.00
IUUC-Fox-037756	Fusarium oxysporum	32.88	1.00e-152	535.00
IUUC-Gmo-039073	Gadus morhua	52.09	3.00e-126	447.00
IUUC-Ggr-039946	Gaeumannomyces graminis	40.00	2.00e-134	474.00
IUUC-Gga-040309	Gallus gallus	56.05	2.00e-97	348.00
IUUC-Gac-042430	Gasterosteus aculeatus	52.09	3.00e-126	448.00
IUUC-Gma-044247	Glycine max	54.36	0.00e+00	1471.00
IUUC-Hsa-046879	Homo sapiens	52.09	7.00e-126	446.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	52.09	3.00e-126	446.00
IUUC-Kpa-049228	Komagataella pastoris	43.58	9.00e-131	462.00
IUUC-Lch-050252	Latimeria chalumnae	52.20	4.00e-125	444.00
IUUC-Lpe-050915	Leersia perrieri	53.20	0.00e+00	1656.00
IUUC-Loc-052472	Lepisosteus oculatus	52.09	3.00e-126	447.00
IUUC-Laf-054154	Loxodonta africana	52.09	5.00e-126	447.00
IUUC-Mcc-055085	Macaca mulatta	52.09	5.00e-126	447.00
IUUC-Mpo-057597	Magnaporthe poae	39.79	2.00e-133	471.00
IUUC-Mtr-058088	Medicago truncatula	52.92	0.00e+00	1541.00
IUUC-Mla-058888	Melampsora laricipopulina	47.07	3.00e-114	404.00
IUUC-Mmr-060820	Microcebus murinus	52.09	4.00e-126	447.00
IUUC-Mdo-062930	Monodelphis domestica	52.09	3.00e-126	447.00
IUUC-Mmu-063601	Mus musculus	52.09	5.00e-126	447.00
IUUC-Mpu-066653	Mustela putorius furo	52.09	6.00e-126	446.00
IUUC-Mlu-067418	Myotis lucifugus	52.09	5.00e-126	447.00
IUUC-Nle-069418	Nomascus leucogenys	52.09	7.00e-126	446.00
IUUC-Opr-070443	Ochotona princeps	44.56	3.00e-94	340.00
IUUC-Ont-071300	Oreochromis niloticus	52.09	2.00e-126	448.00
IUUC-Oan-073046	Ornithorhynchus anatinus	51.85	8.00e-125	443.00
IUUC-Ocu-074178	Oryctolagus cuniculus	52.09	3.00e-126	447.00
IUUC-Oba-075252	Oryza barthii	56.85	0.00e+00	1578.00
IUUC-Obr-076762	Oryza brachyantha	57.74	0.00e+00	1612.00
IUUC-Ogl-077590	Oryza glaberrima	56.40	0.00e+00	1146.00
IUUC-Ogu-077981	Oryza glumaepatula	56.91	0.00e+00	1579.00
IUUC-Oin-079663	Oryza indica	57.37	0.00e+00	1435.00
IUUC-Olo-080326	Oryza longistaminata	57.01	0.00e+00	1575.00
IUUC-Ome-081289	Oryza meridionalis	69.95	0.00e+00	1174.00
IUUC-Oni-082342	Oryza nivara	56.85	0.00e+00	1605.00
IUUC-Opu-083428	Oryza punctata	57.20	0.00e+00	1565.00
IUUC-Oru-084559	Oryza rufipogon	56.78	0.00e+00	1573.00
IUUC-Osa-086200	Oryza sativa	67.15	0.00e+00	1365.00
IUUC-Olu-087813	Ostreococcus lucimarinus	52.55	2.00e-126	445.00
IUUC-Oga-088903	Otolemur garnettii	52.09	4.00e-126	447.00
IUUC-Oar-090210	Ovis aries	52.09	8.00e-126	446.00
IUUC-Ptr-091629	Pan troglodytes	44.81	3.00e-94	339.00
IUUC-Pan-092368	Papio anubis	50.76	5.00e-112	400.00
IUUC-Pma-094364	Petromyzon marinus	43.80	1.00e-87	316.00
IUUC-Ppa-095657	Physcomitrella patens	58.62	0.00e+00	1154.00
IUUC-Pfo-096232	Poecilia formosa	52.09	2.00e-126	448.00
IUUC-Pab-098583	Pongo abelii	52.09	8.00e-126	446.00
IUUC-Pop-099520	Populus trichocarpa	66.27	0.00e+00	1327.00
IUUC-Pca-100596	Procavia capensis	44.85	1.00e-87	317.00
IUUC-Ppe-102109	Prunus persica	56.22	0.00e+00	1654.00
IUUC-Pva-102116	Pteropus vampyrus	48.02	1.00e-111	399.00
IUUC-Sha-106961	Sarcophilus harrisii	52.09	5.00e-126	447.00
IUUC-Sja-107814	Schizosaccharomyces japonicus	41.85	2.00e-131	464.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	44.56	5.00e-95	342.00
IUUC-Smo-109428	Selaginella moellendorffii	45.80	0.00e+00	1249.00
IUUC-Sit-110149	Setaria italica	66.45	0.00e+00	1446.00
IUUC-Sly-111285	Solanum lycopersicum	53.07	0.00e+00	1551.00
IUUC-Stu-112501	Solanum tuberosum	63.76	7.00e-124	436.00
IUUC-Sar-113291	Sorex araneus	51.90	1.00e-121	432.00
IUUC-Sbi-113794	Sorghum bicolor	67.28	0.00e+00	1389.00
IUUC-Ssc-115754	Sus scrofa	52.09	7.00e-126	446.00
IUUC-Tru-118570	Takifugu rubripes	52.09	2.00e-126	448.00
IUUC-Tsy-118806	Tarsius syrichta	44.05	1.00e-91	331.00
IUUC-Tni-120836	Tetraodon nigroviridis	51.27	8.00e-123	436.00
IUUC-Tca-121646	Theobroma cacao	56.35	0.00e+00	1606.00
IUUC-Tvi-122370	Trichoderma virens	39.46	1.00e-142	502.00
IUUC-Tbe-127408	Tupaia belangeri	42.60	2.00e-85	310.00
IUUC-Ttr-129253	Tursiops truncatus	52.09	8.00e-126	446.00
IUUC-Vda-129886	Verticillium dahliae	39.37	2.00e-136	481.00
IUUC-Vpa-130708	Vicugna pacos	52.09	2.00e-125	445.00
IUUC-Vvi-131559	Vitis vinifera	55.42	0.00e+00	1390.00
IUUC-Xtr-132123	Xenopus tropicalis	49.31	3.00e-113	404.00
IUUC-Xma-133869	Xiphophorus maculatus	52.09	1.00e-126	449.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence