iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067252

Ensembl Protein ID

ENSMLUP00000022071.1

UniProt Accession

G1QED8; G1QED8_MYOLU

Genbank Protein ID

ENSMLUP00000022071

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02031661

Gene Name

UBQLN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000007552.2	ENSMLUT00000007537.2	ENSMLUP00000022071.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.70e-10	40.7	583	620
ULD/UDP/UBQ/UBQ_PIM	2.00e-24	85.3	33	106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 583  FQQQLEQLNAMGFlNREANLQALIATGGDINAAIERLL 620
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           +k+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tLs++gi+dg +vhlv+k ++
   Q: 33   IKVTVKTPKEKE-EFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKSQN 106
           69**********.***********************************************************986 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MAENGESSGP PRPSRGPAAA QGSASPPAEP KIIKVTVKTP KEKEEFAVPE NSSVQQFKEA 60
ISKRFKSQTD QLVLIFAGKI LKDQDTLSQH GIHDGLTVHL VIKSQNRPQG QTTQPSTTAG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGAGA ACGGCGAGAG CAGCGGCCCC CCGCGCCCCT CCCGCGGCCC TGCTGCGGCC 60
CAAGGCTCTG CCTCTCCCCC GGCCGAGCCC AAAATCATCA AAGTCACCGT GAAGACCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:1900186--P:negative regulation of clathrin-dependent endocytosis
GO:1904021--P:negative regulation of G-protein coupled receptor internalization
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:2000785--P:regulation of autophagosome assembly
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007963	Ashbya gossypii	29.58	6.00e-11	61.60
IUUC-Acl-008361	Aspergillus clavatus	28.44	8.00e-09	55.10
IUUC-Afl-008403	Aspergillus flavus	26.20	4.00e-09	56.20
IUUC-Afu-009029	Aspergillus fumigatus	27.56	5.00e-09	55.80
IUUC-Ani-009418	Aspergillus nidulans	26.32	6.00e-09	55.50
IUUC-Ang-009826	Aspergillus niger	26.09	1.00e-10	60.80
IUUC-Aor-010091	Aspergillus oryzae	26.20	4.00e-09	56.20
IUUC-Ate-010419	Aspergillus terreus	25.43	3.00e-08	53.10
IUUC-Bta-013571	Bos taurus	88.18	0.00e+00	722.00
IUUC-Cfa-020799	Canis familiaris	89.46	2.00e-174	605.00
IUUC-Cpo-022093	Cavia porcellus	87.79	7.00e-165	573.00
IUUC-Cre-022634	Chlamydomonas reinhardtii	48.15	4.00e-11	62.40
IUUC-Csa-023627	Chlorocebus sabaeus	88.32	0.00e+00	711.00
IUUC-Cho-024552	Choloepus hoffmanni	85.68	2.00e-162	565.00
IUUC-Csv-026009	Ciona savignyi	44.73	9.00e-110	390.00
IUUC-Ete-033071	Echinops telfairi	83.47	0.00e+00	699.00
IUUC-Eeu-034727	Erinaceus europaeus	85.94	0.00e+00	703.00
IUUC-Fca-035803	Felis catus	86.10	1.00e-170	593.00
IUUC-Fso-038204	Fusarium solani	40.30	2.00e-07	50.40
IUUC-Hsa-046768	Homo sapiens	84.94	1.00e-167	582.00
IUUC-Hvu-047094	Hordeum vulgare	50.98	4.00e-09	53.10
IUUC-Itr-048556	Ictidomys tridecemlineatus	85.43	1.00e-173	602.00
IUUC-Lma-053152	Leptosphaeria maculans	32.58	2.00e-12	67.40
IUUC-Mor-057194	Magnaporthe oryzae	48.00	2.00e-07	50.10
IUUC-Mpo-057467	Magnaporthe poae	50.00	5.00e-07	46.20
IUUC-Mmr-061605	Microcebus murinus	87.12	3.00e-163	568.00
IUUC-Mpu-066474	Mustela putorius furo	87.44	3.00e-179	621.00
IUUC-Nfi-068487	Neosartorya fischeri	27.56	2.00e-09	57.00
IUUC-Ncr-068732	Neurospora crassa	48.98	2.00e-07	50.10
IUUC-Nle-069038	Nomascus leucogenys	86.60	0.00e+00	708.00
IUUC-Oga-088005	Otolemur garnettii	85.20	1.00e-167	582.00
IUUC-Oar-089878	Ovis aries	87.86	0.00e+00	726.00
IUUC-Ptr-090781	Pan troglodytes	84.98	5.00e-168	584.00
IUUC-Pan-091716	Papio anubis	83.55	0.00e+00	671.00
IUUC-Pab-097891	Pongo abelii	84.72	6.00e-168	583.00
IUUC-Pca-100227	Procavia capensis	88.19	5.00e-90	325.00
IUUC-Pte-104090	Pyrenophora teres	29.72	5.00e-07	48.90
IUUC-Pyt-104472	Pyrenophora triticirepentis	32.34	4.00e-06	46.20
IUUC-Rno-105748	Rattus norvegicus	85.31	1.00e-167	583.00
IUUC-Sce-106332	Saccharomyces cerevisiae	32.73	2.00e-19	90.10
IUUC-Ssl-108425	Sclerotinia sclerotiorum	50.00	1.00e-06	47.00
IUUC-Sre-115081	Sporisorium reilianum	27.39	4.00e-12	65.90
IUUC-Tsy-119008	Tarsius syrichta	84.56	5.00e-163	567.00
IUUC-Tre-122085	Trichoderma reesei	48.84	6.00e-07	48.50
IUUC-Tvi-122381	Trichoderma virens	48.84	1.00e-06	47.80
IUUC-Uma-129639	Ustilago maydis	28.02	7.00e-12	65.10
IUUC-Vpa-130546	Vicugna pacos	90.54	2.00e-122	432.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence