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Tag Content
UUCD2 ID IUUC-Pab-098337
UUCD1 version UUC-PoA-01089
Ensembl Protein ID ENSPPYP00000004455.2
UniProt Accession H2NFC2; H2NFC2_PONAB
Genbank Protein ID ENSPPYP00000004455
Protein Name Uncharacterized protein
Genbank Nucleotide ID ABGA01010043
Gene Name USP28
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPPYG00000003888.2 ENSPPYT00000004630.2 ENSPPYP00000004455.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 1.30e-58 198.9 162 648
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeef 84
           +GlkN+gNtC++ +v+Q+L+++pe+r+l+l+     +  e+++    ++++  ++++lq lf+ ++ s++k v+p++ l+ lk + ++ 
   Q: 162  VGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSyslpqNVLENCRSH-TEKRNIMFMQELQYLFALMMGSNRKFVDPSAALDLLKGAFRS- 248
           6******************************97665555555543.478888*******************************99987. PP
   S: 85   sgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
           s+ +qqD++Ef++ lld le++++                     + +++ +k+++++++lF g++ ++ + +        +e+f +++
   Q: 249  SEEQQQDVSEFTHKLLDWLEDAFQL------------------AVNVNSPRNKSENPMVQLFYGTFLTEGVREGKPFC--NNETFGQYP 317
           99*********************22..................23467899****************99998665555..5899***** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
           l+v+g +     +l++cLe  + e  +e    +     +++++  ++ +++klP+vL+++L+Rf+f+++ +++eki++k+efp+ + ++
   Q: 318  LQVNGYR-----NLDECLEGAMVEGDVE----LLP--SDHLVKYGQERWFTKLPPVLTFELSRFEFNQSLGQPEKIHNKLEFPQIIYMD 395
           *******.....99****7666555555....444..45678889999***************************************** PP
   S: 263  pfcts.................................................................................... 267
           +++ +                                                                                    
   Q: 396  RYMYRskelirnkrecirklkeeikilqqkleryvkygsgparfplpdmlkyviefastkpasescppesdthvtlplssvhcsvsdqt 484
           *9999778888888888888888888877777777777777777777777777777777777777777777777777777766666655 PP
   S: 268  ...peekqke............................................................................... 274
              +     +                                                                               
   Q: 485  skeS-----Tstesssqdvestfsspedslhkskpltssrssmempsqpaprtvtdeeinfvktclqrwrneieqdiqdlknciasttq 568
           5550.....05555556666677777777777777778888888888888888888888888888999999999999999999999999 PP
   S: 275  ............kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                       ++ Y+L+av+vH+G+++ GHY+ay++n+ ++ Wl+++D +Vte+++eev++++       +aY+l+Y 
   Q: 569  tieemycdpllrQVPYRLHAVLVHEGQANAGHYWAYIYNQPRQsWLKYNDISVTESSWEEVERDSYgglrnVSAYCLMYI 648
           9999*******9***************************88888*******************8879************6 PP
   
Organism Pongo abelii
Protein Sequence
(Fasta)
MTAELQQDDA AGAADGHGSS CQMLLNQLRE ITGIQDPSFL HEALKASNGD ITQAVSLLTD 60
ERVKEPSQDT VATEPSEVEG SAANKEVLAK VIDLTHDNKD DLQAAIALSL LESPKIQADG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Pab-098337|DUB,USP|Pongo abelii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGGGCGGGAC GGAGCGGGGT GGAGGGTGGG GGCGGGGCCT AGTTGTGAGA GGCTGGGCCG 60
GCGGCGGCTG CGGCGGGAGA CTGGTGACCC GCGGCTGGGC GCCTCGGCCA TGACTGCGGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Pab-098337|DUB,USP|Pongo abelii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
Gene Ontology

GO:0016604--C:nuclear body
GO:0043234--C:protein complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008283--P:cell proliferation
GO:0034644--P:cellular response to UV
GO:0000077--P:DNA damage checkpoint
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0016579--P:protein deubiquitination
GO:0007265--P:Ras protein signal transduction
GO:0031647--P:regulation of protein stability
GO:0010212--P:response to ionizing radiation
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001836 Ailuropoda melanoleuca 94.54 0.00e+00 2024.00
IUUC-Apl-004010 Anas platyrhynchos 70.32 0.00e+00 1479.00
IUUC-Aca-004741 Anolis carolinensis 58.31 0.00e+00 843.00
IUUC-Ang-009577 Aspergillus niger 36.36 2.00e-11 65.10
IUUC-Ate-010275 Aspergillus terreus 34.95 1.00e-10 62.80
IUUC-Bta-013377 Bos taurus 93.07 0.00e+00 1959.00
IUUC-Cja-019977 Callithrix jacchus 98.61 0.00e+00 2078.00
IUUC-Cfa-020378 Canis familiaris 93.07 0.00e+00 1382.00
IUUC-Cpo-021817 Cavia porcellus 91.26 0.00e+00 1945.00
IUUC-Csa-023446 Chlorocebus sabaeus 98.57 0.00e+00 1457.00
IUUC-Cho-024717 Choloepus hoffmanni 84.58 0.00e+00 1223.00
IUUC-Csv-025911 Ciona savignyi 35.26 9.00e-142 497.00
IUUC-Cme-027167 Cyanidioschyzon merolae 33.00 8.00e-16 79.70
IUUC-Dre-028105 Danio rerio 56.32 0.00e+00 708.00
IUUC-Dno-029559 Dasypus novemcinctus 91.14 0.00e+00 1507.00
IUUC-Dor-030955 Dipodomys ordii 91.29 0.00e+00 1942.00
IUUC-Ete-032828 Echinops telfairi 81.82 0.00e+00 1169.00
IUUC-Eca-034300 Equus caballus 94.35 0.00e+00 1945.00
IUUC-Eeu-034458 Erinaceus europaeus 89.41 0.00e+00 1721.00
IUUC-Fca-035753 Felis catus 94.17 0.00e+00 2010.00
IUUC-Fal-037062 Ficedula albicollis 64.16 0.00e+00 882.00
IUUC-Gmo-039593 Gadus morhua 51.96 0.00e+00 1031.00
IUUC-Gga-040878 Gallus gallus 65.00 0.00e+00 1324.00
IUUC-Gac-041867 Gasterosteus aculeatus 54.45 0.00e+00 1105.00
IUUC-Ggo-045384 Gorilla gorilla 99.07 0.00e+00 2084.00
IUUC-Hsa-046277 Homo sapiens 99.26 0.00e+00 2088.00
IUUC-Itr-048276 Ictidomys tridecemlineatus 87.88 0.00e+00 1154.00
IUUC-Lch-049692 Latimeria chalumnae 66.23 0.00e+00 1395.00
IUUC-Laf-053808 Loxodonta africana 88.98 0.00e+00 1842.00
IUUC-Mcc-055473 Macaca mulatta 98.57 0.00e+00 1457.00
IUUC-Meu-056416 Macropus eugenii 75.31 0.00e+00 1518.00
IUUC-Mga-060011 Meleagris gallopavo 67.85 0.00e+00 1407.00
IUUC-Mmr-060720 Microcebus murinus 93.09 0.00e+00 1933.00
IUUC-Mdo-061955 Monodelphis domestica 85.31 0.00e+00 1312.00
IUUC-Mmu-063870 Mus musculus 87.44 0.00e+00 1881.00
IUUC-Mpu-066454 Mustela putorius furo 91.47 0.00e+00 1330.00
IUUC-Mlu-067487 Myotis lucifugus 88.44 0.00e+00 1860.00
IUUC-Nle-070044 Nomascus leucogenys 99.07 0.00e+00 2085.00
IUUC-Opr-070888 Ochotona princeps 98.19 4.00e-162 565.00
IUUC-Ocu-074523 Oryctolagus cuniculus 91.24 0.00e+00 1940.00
IUUC-Ola-086393 Oryzias latipes 54.19 0.00e+00 1101.00
IUUC-Oga-088618 Otolemur garnettii 94.80 0.00e+00 1985.00
IUUC-Oar-089848 Ovis aries 84.58 0.00e+00 1828.00
IUUC-Ptr-091630 Pan troglodytes 99.03 0.00e+00 1585.00
IUUC-Psi-093422 Pelodiscus sinensis 65.17 0.00e+00 1390.00
IUUC-Pma-094250 Petromyzon marinus 52.27 4.00e-73 267.00
IUUC-Pfo-096466 Poecilia formosa 55.13 0.00e+00 741.00
IUUC-Pca-100901 Procavia capensis 78.33 0.00e+00 1614.00
IUUC-Pva-102226 Pteropus vampyrus 88.71 0.00e+00 1736.00
IUUC-Rno-105735 Rattus norvegicus 84.51 0.00e+00 1868.00
IUUC-Sha-107489 Sarcophilus harrisii 87.80 0.00e+00 1865.00
IUUC-Ssl-108532 Sclerotinia sclerotiorum 35.80 7.00e-09 56.60
IUUC-Tgu-116609 Taeniopygia guttata 69.28 0.00e+00 1422.00
IUUC-Tru-117807 Takifugu rubripes 54.20 0.00e+00 1086.00
IUUC-Tsy-118971 Tarsius syrichta 88.97 0.00e+00 1251.00
IUUC-Tni-119983 Tetraodon nigroviridis 54.39 0.00e+00 1101.00
IUUC-Ttr-128887 Tursiops truncatus 88.54 0.00e+00 1852.00
IUUC-Vpa-130614 Vicugna pacos 92.41 0.00e+00 1501.00
IUUC-Xtr-132436 Xenopus tropicalis 63.94 0.00e+00 1299.00
Created Date 25-Jun-2017

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