iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001470

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01003106

Gene Name

ATG16L2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000005345.1	ENSAMET00000005911.1	ENSAMEP00000005673.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-27	94.6	325	360
UBD/Beta-Prp	4.80e-47	160.6	323	608

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           H ++v++++f ++  ll++G+ D  i++W++  g+l
   Q: 325  HLSEVNAVCFgPNsSLLATGGADRLIRLWSVVGGRL 360
           99*********7779***************987765 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++h s +++v+f p++sllatg++d+ i++w+v  g l   ++l+g  + +t+v+f+p+g+  + +   +++++w +   +   tl+gh
   Q: 323  DAHLSEVNAVCFGPNSSLLATGGADRLIRLWSVVGGRLeaNQTLEGAAGSITSVDFDPSGSQVLAATYNQAAQLWKVGEVQSKETLSGH 411
           7899999*******************************88899******************9999999********************* PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           +d+v++ +f  +++  v+Gs+drt++ wdl   +c++ t ++ +    c  v + + +++sG++D+++r+Wd++  ++ +      +++
   Q: 412  TDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSR-TINVLS---YCNDVVCGDHVIISGHNDQKIRFWDSRVPCCTQVIP--VQGR 494
           ************************************9.666665...4555555556*************************5..589* PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
           v+sl++++++ +l+s+s+d t+k+ dl+ +++ + +++       d++k   fsp+  + + gs Dg ++iW++++g+l ++l +++ s
   Q: 495  VTSLNLSHDQLHLLSCSRDDTLKVIDLRVSNIRQVFRADGfrcgsDWTK-AVFSPDRSYALAGSWDGALYIWNVDTGKLEGSLRGPHCS 582
           ****************************888855555544445526666.8899*********************************88 PP
   S: 267  visvavlsfgdnvlvlgsedskvniw 292
            +   +++++++++v++++  k+ +w
   Q: 583  QVNAVAWCPSGSHVVSAEQARKAVLW 608
           8877778***********99999988 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MAGPGAPGVP VARWKRHIVR QLRQRDRTQK ALFLELVPAY NHLLEKAELL ARISEKLQPE 60
PNDVTPATLQ GPWEEESGPD SDQVLSPTTL RVKWQEEEER VRRDCGEMPS YSMPPYLPNE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGGGC CCGGCGCCCC CGGCGTGCCT GTCGCCCGCT GGAAACGCCA CATAGTGCGG 60
CAGCTTCGGC AGCGGGACCG CACGCAAAAG GCGCTCTTCC TGGAGCTGGT GCCGGCCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000090	Aegilops tauschii	29.33	7.00e-30	125.00
IUUC-Ath-006948	Arabidopsis thaliana	30.77	4.00e-40	159.00
IUUC-Ame-011152	Astyanax mexicanus	39.50	7.00e-103	367.00
IUUC-Bta-013118	Bos taurus	66.61	0.00e+00	724.00
IUUC-Bdi-014231	Brachypodium distachyon	30.45	7.00e-33	135.00
IUUC-Cja-020002	Callithrix jacchus	67.68	0.00e+00	696.00
IUUC-Cfa-020878	Canis familiaris	71.57	0.00e+00	801.00
IUUC-Cpo-022476	Cavia porcellus	66.56	0.00e+00	724.00
IUUC-Csa-024134	Chlorocebus sabaeus	68.58	0.00e+00	728.00
IUUC-Cho-024853	Choloepus hoffmanni	62.09	6.00e-140	490.00
IUUC-Dre-027949	Danio rerio	38.84	2.00e-110	392.00
IUUC-Dno-029683	Dasypus novemcinctus	75.30	7.00e-175	606.00
IUUC-Dor-030897	Dipodomys ordii	73.07	9.00e-180	623.00
IUUC-Ete-032957	Echinops telfairi	91.24	5.00e-127	447.00
IUUC-Eca-033303	Equus caballus	89.58	3.00e-142	497.00
IUUC-Eeu-035336	Erinaceus europaeus	88.81	1.00e-140	493.00
IUUC-Fca-036232	Felis catus	72.04	0.00e+00	829.00
IUUC-Gmo-038880	Gadus morhua	50.35	4.00e-70	258.00
IUUC-Gma-043452	Glycine max	32.78	4.00e-42	166.00
IUUC-Ggo-045130	Gorilla gorilla	76.33	3.00e-158	551.00
IUUC-Hsa-046359	Homo sapiens	68.84	0.00e+00	688.00
IUUC-Hvu-047655	Hordeum vulgare	28.32	1.00e-22	100.00
IUUC-Itr-048780	Ictidomys tridecemlineatus	67.05	0.00e+00	708.00
IUUC-Lch-050669	Latimeria chalumnae	57.79	5.00e-88	317.00
IUUC-Loc-052789	Lepisosteus oculatus	38.83	3.00e-103	369.00
IUUC-Laf-053699	Loxodonta africana	67.03	0.00e+00	692.00
IUUC-Mcc-055657	Macaca mulatta	65.92	0.00e+00	660.00
IUUC-Mmr-061314	Microcebus murinus	63.07	0.00e+00	634.00
IUUC-Mdo-061841	Monodelphis domestica	54.46	9.00e-163	566.00
IUUC-Mmu-064065	Mus musculus	65.25	0.00e+00	718.00
IUUC-Mac-065022	Musa acuminata	32.05	2.00e-37	149.00
IUUC-Mpu-066742	Mustela putorius furo	81.05	0.00e+00	630.00
IUUC-Mlu-067019	Myotis lucifugus	76.67	2.00e-159	555.00
IUUC-Nle-069037	Nomascus leucogenys	68.38	0.00e+00	691.00
IUUC-Opr-071039	Ochotona princeps	74.88	5.00e-171	594.00
IUUC-Oan-073431	Ornithorhynchus anatinus	74.57	6.00e-126	443.00
IUUC-Ocu-074772	Oryctolagus cuniculus	65.48	2.00e-174	605.00
IUUC-Oba-075619	Oryza barthii	29.39	1.00e-30	127.00
IUUC-Obr-076632	Oryza brachyantha	29.72	2.00e-32	133.00
IUUC-Ogl-077671	Oryza glaberrima	29.39	2.00e-30	127.00
IUUC-Ome-081560	Oryza meridionalis	29.39	1.00e-30	127.00
IUUC-Oni-082145	Oryza nivara	29.39	1.00e-30	127.00
IUUC-Opu-083918	Oryza punctata	28.06	2.00e-30	127.00
IUUC-Ola-086964	Oryzias latipes	52.61	7.00e-83	300.00
IUUC-Oga-088188	Otolemur garnettii	75.29	1.00e-166	579.00
IUUC-Oar-090231	Ovis aries	65.22	0.00e+00	702.00
IUUC-Ptr-091434	Pan troglodytes	68.52	0.00e+00	677.00
IUUC-Pan-091868	Papio anubis	69.60	0.00e+00	724.00
IUUC-Psi-093652	Pelodiscus sinensis	56.58	3.00e-134	471.00
IUUC-Pab-097776	Pongo abelii	76.87	5.00e-162	564.00
IUUC-Pca-100220	Procavia capensis	72.37	9.00e-81	294.00
IUUC-Ppe-101790	Prunus persica	30.90	2.00e-40	160.00
IUUC-Pva-103135	Pteropus vampyrus	77.97	1.00e-165	576.00
IUUC-Rno-105529	Rattus norvegicus	64.96	0.00e+00	733.00
IUUC-Sha-107062	Sarcophilus harrisii	55.64	9.00e-171	593.00
IUUC-Sar-113109	Sorex araneus	84.07	5.00e-101	361.00
IUUC-Sbi-114819	Sorghum bicolor	31.61	1.00e-36	147.00
IUUC-Ssc-115271	Sus scrofa	69.52	0.00e+00	706.00
IUUC-Tae-123139	Triticum aestivum	29.00	1.00e-30	127.00
IUUC-Tur-126463	Triticum urartu	29.00	5.00e-30	125.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence