iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054559

UUCD1 version

UUC-LoA-00059

Ensembl Protein ID

ENSLAFP00000001623.2

UniProt Accession

G3SPI5; G3SPI5_LOXAF

Protein Name

Uncharacterized protein

Gene Name

RFWD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000001941.2	ENSLAFT00000001940.2	ENSLAFP00000001623.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.60e-06	26.9	438	476

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvllk 37
           H   +++laf   + +ll+s+s D t+k+ +l t+++++
   Q: 438  HGKQIRGLAFssRSkGLLLSASLDSTLKLTSLETNTVVQ 476
           8889******99446*************98888877766 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

EPPPAEVVNS QTGLPLLQPA PQVSIDLTEE GAPSGEESVE NIDPGASEED RRGSGANPTV 60
RVSSLESVNT FISGLQRLHG MLEFLRPPPS NHSVGPVRIR RRRGSAVRRA RPGGSQRTDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGCCGCCTC CTGCTGAAGT GGTCAACAGC CAAACAGGAC TGCCTCTGCT CCAGCCTGCG 60
CCGCAGGTGT CTATTGACCT GACAGAGGAA GGGGCGCCCT CAGGAGAAGA GAGTGTGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0035861--C:site of double-strand break
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0031571--P:mitotic G1 DNA damage checkpoint
GO:2000001--P:regulation of DNA damage checkpoint
GO:0010212--P:response to ionizing radiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000929	Aegilops tauschii	26.64	2.00e-15	77.40
IUUC-Aml-001188	Ailuropoda melanoleuca	80.92	0.00e+00	1022.00
IUUC-Atr-003034	Amborella trichopoda	34.21	5.00e-14	71.60
IUUC-Apl-003182	Anas platyrhynchos	68.94	0.00e+00	634.00
IUUC-Aca-004619	Anolis carolinensis	70.09	0.00e+00	665.00
IUUC-Aly-006391	Arabidopsis lyrata	28.75	1.00e-29	124.00
IUUC-Ath-007300	Arabidopsis thaliana	27.92	3.00e-27	116.00
IUUC-Ame-010890	Astyanax mexicanus	58.61	7.00e-159	553.00
IUUC-Bta-013051	Bos taurus	73.55	0.00e+00	896.00
IUUC-Bdi-014519	Brachypodium distachyon	27.80	5.00e-20	92.80
IUUC-Bol-015271	Brassica oleracea	30.16	1.00e-28	121.00
IUUC-Bra-017931	Brassica rapa	31.19	1.00e-28	121.00
IUUC-Cja-019240	Callithrix jacchus	73.66	0.00e+00	956.00
IUUC-Cfa-021010	Canis familiaris	78.49	0.00e+00	971.00
IUUC-Cpo-022308	Cavia porcellus	72.51	0.00e+00	887.00
IUUC-Csa-023501	Chlorocebus sabaeus	76.91	0.00e+00	979.00
IUUC-Cho-024900	Choloepus hoffmanni	73.71	0.00e+00	898.00
IUUC-Cin-025403	Ciona intestinalis	37.99	1.00e-87	317.00
IUUC-Csv-025819	Ciona savignyi	39.13	9.00e-36	143.00
IUUC-Cme-027123	Cyanidioschyzon merolae	25.14	1.00e-16	80.90
IUUC-Dre-028354	Danio rerio	55.41	1.00e-143	503.00
IUUC-Dno-029400	Dasypus novemcinctus	79.97	0.00e+00	987.00
IUUC-Dor-030320	Dipodomys ordii	68.55	0.00e+00	716.00
IUUC-Dme-031949	Drosophila melanogaster	27.75	2.00e-36	147.00
IUUC-Ete-032691	Echinops telfairi	62.92	8.00e-145	507.00
IUUC-Eca-034320	Equus caballus	79.94	0.00e+00	1017.00
IUUC-Fca-035732	Felis catus	76.59	0.00e+00	974.00
IUUC-Fal-036648	Ficedula albicollis	70.04	0.00e+00	646.00
IUUC-Gmo-038609	Gadus morhua	56.03	1.00e-117	416.00
IUUC-Gga-040522	Gallus gallus	70.16	2.00e-105	375.00
IUUC-Gac-042318	Gasterosteus aculeatus	54.32	1.00e-112	399.00
IUUC-Gma-043184	Glycine max	30.35	1.00e-24	108.00
IUUC-Ggo-044464	Gorilla gorilla	74.89	0.00e+00	956.00
IUUC-Hsa-045991	Homo sapiens	74.61	0.00e+00	954.00
IUUC-Hvu-047705	Hordeum vulgare	28.86	9.00e-26	111.00
IUUC-Itr-047977	Ictidomys tridecemlineatus	80.30	0.00e+00	1005.00
IUUC-Lch-050112	Latimeria chalumnae	64.81	1.00e-167	583.00
IUUC-Lpe-051605	Leersia perrieri	25.95	5.00e-18	86.30
IUUC-Loc-052241	Lepisosteus oculatus	60.49	2.00e-159	555.00
IUUC-Mcc-055093	Macaca mulatta	74.89	0.00e+00	960.00
IUUC-Meu-056417	Macropus eugenii	66.23	7.00e-178	616.00
IUUC-Mtr-058533	Medicago truncatula	27.81	2.00e-29	124.00
IUUC-Mga-059498	Meleagris gallopavo	59.97	2.00e-178	619.00
IUUC-Mmr-061782	Microcebus murinus	76.25	0.00e+00	946.00
IUUC-Mdo-062053	Monodelphis domestica	72.00	0.00e+00	676.00
IUUC-Mmu-063352	Mus musculus	68.45	0.00e+00	901.00
IUUC-Mac-064582	Musa acuminata	27.18	2.00e-21	97.80
IUUC-Mpu-066087	Mustela putorius furo	79.11	0.00e+00	985.00
IUUC-Mlu-068147	Myotis lucifugus	74.93	0.00e+00	918.00
IUUC-Nle-069503	Nomascus leucogenys	70.73	0.00e+00	887.00
IUUC-Opr-070479	Ochotona princeps	66.32	0.00e+00	802.00
IUUC-Ont-071700	Oreochromis niloticus	56.21	2.00e-147	516.00
IUUC-Oan-073702	Ornithorhynchus anatinus	73.05	0.00e+00	697.00
IUUC-Ocu-074886	Oryctolagus cuniculus	73.89	0.00e+00	957.00
IUUC-Oba-075729	Oryza barthii	28.48	8.00e-23	101.00
IUUC-Obr-076562	Oryza brachyantha	28.03	1.00e-20	94.40
IUUC-Ogl-077615	Oryza glaberrima	28.48	8.00e-23	101.00
IUUC-Ogu-078921	Oryza glumaepatula	28.38	3.00e-23	103.00
IUUC-Oin-079250	Oryza indica	25.32	7.00e-18	85.50
IUUC-Olo-080758	Oryza longistaminata	28.57	1.00e-23	104.00
IUUC-Ome-081707	Oryza meridionalis	25.65	3.00e-19	90.10
IUUC-Oni-083006	Oryza nivara	28.38	8.00e-23	102.00
IUUC-Opu-083650	Oryza punctata	27.27	5.00e-23	102.00
IUUC-Oru-084924	Oryza rufipogon	28.19	2.00e-23	103.00
IUUC-Osa-085820	Oryza sativa	28.38	7.00e-23	102.00
IUUC-Ola-087229	Oryzias latipes	54.81	7.00e-115	407.00
IUUC-Oga-088243	Otolemur garnettii	73.74	0.00e+00	924.00
IUUC-Oar-089461	Ovis aries	74.23	0.00e+00	925.00
IUUC-Ptr-090527	Pan troglodytes	74.75	0.00e+00	950.00
IUUC-Pan-092431	Papio anubis	77.03	0.00e+00	977.00
IUUC-Psi-093156	Pelodiscus sinensis	69.94	0.00e+00	684.00
IUUC-Pno-094897	Phaeosphaeria nodorum	22.69	6.00e-08	51.60
IUUC-Ppa-095305	Physcomitrella patens	36.80	8.00e-19	89.40
IUUC-Pfo-097065	Poecilia formosa	54.70	1.00e-141	496.00
IUUC-Pab-098272	Pongo abelii	76.91	0.00e+00	972.00
IUUC-Pop-099827	Populus trichocarpa	30.73	6.00e-32	132.00
IUUC-Pca-100713	Procavia capensis	75.11	0.00e+00	910.00
IUUC-Ppe-102103	Prunus persica	28.07	2.00e-28	120.00
IUUC-Pva-103133	Pteropus vampyrus	85.29	0.00e+00	667.00
IUUC-Ptt-103972	Puccinia triticina	32.89	1.00e-05	44.70
IUUC-Pyt-104734	Pyrenophora triticirepentis	46.94	7.00e-07	47.80
IUUC-Sha-107628	Sarcophilus harrisii	73.61	0.00e+00	692.00
IUUC-Sit-109781	Setaria italica	29.84	1.00e-24	107.00
IUUC-Sly-111779	Solanum lycopersicum	31.63	1.00e-30	127.00
IUUC-Stu-112817	Solanum tuberosum	42.86	4.00e-19	88.60
IUUC-Sar-113124	Sorex araneus	68.28	0.00e+00	678.00
IUUC-Sbi-114107	Sorghum bicolor	25.97	4.00e-26	113.00
IUUC-Ssc-115850	Sus scrofa	78.27	0.00e+00	954.00
IUUC-Tgu-117295	Taeniopygia guttata	69.48	0.00e+00	656.00
IUUC-Tru-117539	Takifugu rubripes	55.07	1.00e-142	499.00
IUUC-Tsy-118805	Tarsius syrichta	68.47	1.00e-111	397.00
IUUC-Tni-120274	Tetraodon nigroviridis	56.42	7.00e-146	510.00
IUUC-Tca-121162	Theobroma cacao	31.37	8.00e-31	128.00
IUUC-Tae-124822	Triticum aestivum	28.80	7.00e-27	115.00
IUUC-Tur-126162	Triticum urartu	26.49	9.00e-18	85.50
IUUC-Tbe-127884	Tupaia belangeri	66.22	7.00e-69	254.00
IUUC-Ttr-128665	Tursiops truncatus	85.66	2.00e-135	476.00
IUUC-Vpa-130385	Vicugna pacos	80.42	0.00e+00	988.00
IUUC-Vvi-131464	Vitis vinifera	30.82	3.00e-24	106.00
IUUC-Xtr-132015	Xenopus tropicalis	60.85	0.00e+00	633.00
IUUC-Xma-133109	Xiphophorus maculatus	54.73	1.00e-139	490.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence