iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tca-121392

Ensembl Protein ID

EOY28892

UniProt Accession

A0A061GI97; A0A061GI97_THECC

Genbank Protein ID

EOY28892.1

Protein Name

E3 ubiquitin-protein ligase UPL5

Genbank Nucleotide ID

CM001884

Gene Name

TCM_030368

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TCM_030368	EOY28892	EOY28892

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.60e-92	310.7	561	892
ULD/UDP/UBQ/UBQ_Other	6.00e-10	39.8	117	179

Active Site

Position(s)	Description	Evidence
865	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllgk 103
           ++l++ l++ef++Ee+++  Gv re+++l++++++np++ lf+  +nd++ ++pnp+s + +p hl++F f+Gr++++al+++  + + + ++f+ +l g 
   Q: 561  ESLHAGLFMEFKNEEATGP-GVLREWFFLVCQAIFNPENALFVPCSNDRRRFFPNPASRV-DPLHLEYFSFAGRVIALALMHKVQVGVVFDRVFFLQLAGM 659
           6788899***********9.***************************************9.68************************************** PP
   S: 104  klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviple 204
            +sled+ e dp ly s k+i+e++ + i+  +l ltf ++ e+lg++++ eL+pgG++i V+  N++eYv+l++  r+ ++i eqv +f +Gf+ +++ +
   Q: 660  HISLEDIREADPCLYSSCKKILEMDAEFIDSDALGLTFVREIEELGSRRVMELCPGGKSIVVNSRNRQEYVNLLIRDRFVTSISEQVYHFAQGFSHILSNS 760
           *************************9***********************************************************************8887 PP
   S: 205  llslF.....teeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasddrlP 299
            l+ F     + e+l+ ++ G+ + i+ved+k++t+y+ gy e++p+i wFwe+++e+s+e+rk +L F+T+ + lP++Gf+ l  rl++++ ++ ++rlP
   Q: 761  RLQKFffqslELEDLDWMLYGSeSPISVEDWKAHTEYN-GYRENDPQITWFWEIVREMSAEQRKVLLFFWTSVKNLPVEGFRGLASRLYIYKSSEPHERLP 860
           66654222227788889*****999************5.5*****************************************************9999**** PP
   S: 300  ssnTCfnyLkLPeYsskeilkekLlyAieetk 331
           ss+TCf++L+ P+Y+s+++++++ ++ ++e  
   Q: 861  SSHTCFYRLCFPPYPSMTEMQKRFRVVTQEHV 892
           ************************99998874 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekks 74
           +  ++ n+ dtV+ L e+i+  +gip+ +qrLiy+Gk L+  ++Lad+ ++++  + l+ +++
   Q: 117  TIVVHANSEDTVKSLHERIQLMTGIPVIEQRLIYRGKQLQWEQSLADCAIQNDAGLQLVGRMR 179
           556678999******************************9999*************9999876 PP

Organism

Theobroma cacao

Protein Sequence
(Fasta)

MSLFQSPAVD QFSNGCDHRL SSKRKFDDYA LAFDEADEDE APLVPVRMRK DDHHHHLHHQ 60
GSHPITAVQP SSKGSSSSSP ASFLDSRPSS SDAPSSSASC SSSRLQFFIR MISEGNTIVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAATCAAGTG AGCAAACTTA AAGATCATCC AATCCATGCA TTCAAAGAGA GAAGAGTTAA 60
ATTAACATCG TAGCCGTCAA AAGTGATGGG AGATCAAACA TGGTGCGACC GTCCGCAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR019956--Ubiquitin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50237--HECT
PS50053--UBIQUITIN_2

Pfam

PF00632--HECT
PF00240--ubiquitin

PRINTS

PR00348--UBIQUITIN

SMART

SM00119--HECTc
SM00213--UBQ

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

tcc:TCM_030368

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000327	Aegilops tauschii	43.29	1.00e-167	582.00
IUUC-Atr-002891	Amborella trichopoda	46.42	0.00e+00	717.00
IUUC-Aly-005570	Arabidopsis lyrata	55.44	0.00e+00	878.00
IUUC-Ath-007126	Arabidopsis thaliana	54.27	0.00e+00	871.00
IUUC-Bdi-014613	Brachypodium distachyon	43.81	0.00e+00	638.00
IUUC-Bol-016237	Brassica oleracea	53.07	0.00e+00	833.00
IUUC-Bra-017376	Brassica rapa	52.70	0.00e+00	829.00
IUUC-Gma-043346	Glycine max	64.56	0.00e+00	1153.00
IUUC-Hvu-047734	Hordeum vulgare	44.16	0.00e+00	630.00
IUUC-Lpe-051617	Leersia perrieri	42.89	5.00e-159	554.00
IUUC-Mtr-058709	Medicago truncatula	61.60	0.00e+00	983.00
IUUC-Mac-065415	Musa acuminata	48.43	0.00e+00	702.00
IUUC-Oba-075190	Oryza barthii	47.25	1.00e-156	546.00
IUUC-Obr-076197	Oryza brachyantha	45.36	4.00e-177	614.00
IUUC-Ogl-077892	Oryza glaberrima	42.68	3.00e-155	541.00
IUUC-Ogu-078711	Oryza glumaepatula	43.67	3.00e-162	565.00
IUUC-Oin-079504	Oryza indica	42.80	3.00e-158	551.00
IUUC-Olo-080730	Oryza longistaminata	47.40	4.00e-157	547.00
IUUC-Ome-081851	Oryza meridionalis	44.15	5.00e-168	584.00
IUUC-Oni-082230	Oryza nivara	43.67	6.00e-162	564.00
IUUC-Opu-084015	Oryza punctata	43.98	1.00e-163	569.00
IUUC-Oru-084327	Oryza rufipogon	43.67	3.00e-162	565.00
IUUC-Osa-086148	Oryza sativa	42.80	2.00e-156	545.00
IUUC-Ppa-095337	Physcomitrella patens	44.24	0.00e+00	683.00
IUUC-Pop-099556	Populus trichocarpa	63.72	0.00e+00	1026.00
IUUC-Ppe-101443	Prunus persica	64.72	0.00e+00	1137.00
IUUC-Smo-109099	Selaginella moellendorffii	43.84	0.00e+00	667.00
IUUC-Sit-110651	Setaria italica	42.37	4.00e-171	594.00
IUUC-Sly-111513	Solanum lycopersicum	64.76	0.00e+00	1057.00
IUUC-Stu-112582	Solanum tuberosum	65.26	0.00e+00	1063.00
IUUC-Sbi-114659	Sorghum bicolor	40.33	1.00e-131	462.00
IUUC-Tae-125860	Triticum aestivum	39.39	4.00e-152	531.00
IUUC-Tur-126774	Triticum urartu	46.76	4.00e-171	593.00
IUUC-Vvi-131149	Vitis vinifera	71.45	0.00e+00	1156.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence