iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073399

Ensembl Protein ID

ENSOANP00000018879.3

UniProt Accession

F6S2E1; F6S2E1_ORNAN

Protein Name

Uncharacterized protein

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000011911.3	ENSOANT00000018882.3	ENSOANP00000018879.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	86.44	5.00e-152	534.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

GGCGVSRVAL KKYHFSRAAN IPEKREVPSQ KEAPCQKNEE SKKRQWSLDD FDIGRPLGKG 60
KFGNVYLARE KQSKFILALK VLFKGQLEKA GVEHQLRREV EIQSHLRHPN ILRLYGYFHD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCTTTTGAG TAATTAAGGC CAAAGAGCTA TTGGAGATGC AGCAGAGCAC CGTGAAACTT 60
CCAGCATGTT TCCAATGCTT TCCCCACTTC TGTCAGAAGT ATTTCCAGAC TTTTGGCAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0032133--C:chromosome passenger complex
GO:0000780--C:condensed nuclear chromosome, centromeric region
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0051233--C:spindle midzone
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0032465--P:regulation of cytokinesis
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	66.43	3.00e-106	377.00
IUUC-Aml-001426	Ailuropoda melanoleuca	90.61	1.00e-150	525.00
IUUC-Atr-002453	Amborella trichopoda	68.42	9.00e-108	382.00
IUUC-Apl-003626	Anas platyrhynchos	90.04	2.00e-150	524.00
IUUC-Aca-004602	Anolis carolinensis	83.22	3.00e-145	507.00
IUUC-Aly-005878	Arabidopsis lyrata	65.68	2.00e-106	377.00
IUUC-Ath-007117	Arabidopsis thaliana	66.79	1.00e-106	378.00
IUUC-Acl-008199	Aspergillus clavatus	55.44	2.00e-87	315.00
IUUC-Afl-008419	Aspergillus flavus	55.36	6.00e-86	310.00
IUUC-Afu-008751	Aspergillus fumigatus	55.40	1.00e-86	313.00
IUUC-Ani-009181	Aspergillus nidulans	54.74	2.00e-91	328.00
IUUC-Ang-009787	Aspergillus niger	56.27	5.00e-87	313.00
IUUC-Aor-009980	Aspergillus oryzae	55.36	6.00e-86	310.00
IUUC-Ate-010286	Aspergillus terreus	55.40	2.00e-87	315.00
IUUC-Ame-010849	Astyanax mexicanus	73.22	5.00e-132	463.00
IUUC-Bgr-012110	Blumeria graminis	58.82	2.00e-87	315.00
IUUC-Bta-013474	Bos taurus	83.71	1.00e-152	531.00
IUUC-Bci-013756	Botrytis cinerea	57.49	2.00e-95	342.00
IUUC-Bdi-014257	Brachypodium distachyon	66.06	7.00e-106	375.00
IUUC-Bol-016310	Brassica oleracea	67.17	1.00e-104	372.00
IUUC-Bra-017438	Brassica rapa	64.16	1.00e-105	375.00
IUUC-Cel-018157	Caenorhabditis elegans	59.57	2.00e-100	358.00
IUUC-Cja-019282	Callithrix jacchus	87.12	5.00e-154	536.00
IUUC-Cfa-020162	Canis familiaris	80.91	7.00e-151	526.00
IUUC-Cpo-021764	Cavia porcellus	86.36	2.00e-150	524.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	69.55	3.00e-110	390.00
IUUC-Csa-023694	Chlorocebus sabaeus	86.78	7.00e-154	535.00
IUUC-Cho-024350	Choloepus hoffmanni	91.33	3.00e-105	373.00
IUUC-Cin-025542	Ciona intestinalis	73.76	1.00e-118	418.00
IUUC-Csv-025873	Ciona savignyi	73.95	3.00e-119	420.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	54.81	2.00e-81	295.00
IUUC-Cne-026928	Cryptococcus neoformans	61.48	1.00e-95	342.00
IUUC-Cme-027336	Cyanidioschyzon merolae	72.01	7.00e-120	423.00
IUUC-Dre-028198	Danio rerio	77.07	2.00e-130	457.00
IUUC-Dno-029928	Dasypus novemcinctus	91.95	2.00e-146	511.00
IUUC-Dor-030238	Dipodomys ordii	76.22	6.00e-134	469.00
IUUC-Dse-031266	Dothistroma septosporum	53.90	1.00e-92	332.00
IUUC-Dme-032007	Drosophila melanogaster	63.36	9.00e-102	362.00
IUUC-Ete-032911	Echinops telfairi	69.88	2.00e-101	361.00
IUUC-Eca-033749	Equus caballus	89.53	1.00e-149	521.00
IUUC-Eeu-035170	Erinaceus europaeus	85.47	1.00e-147	515.00
IUUC-Fca-035498	Felis catus	83.86	3.00e-155	540.00
IUUC-Fal-037397	Ficedula albicollis	86.74	5.00e-149	520.00
IUUC-Fox-037747	Fusarium oxysporum	53.82	2.00e-91	328.00
IUUC-Fso-038429	Fusarium solani	50.76	1.00e-89	322.00
IUUC-Gmo-039378	Gadus morhua	71.43	5.00e-129	453.00
IUUC-Ggr-039939	Gaeumannomyces graminis	57.64	7.00e-95	340.00
IUUC-Gga-040187	Gallus gallus	88.89	5.00e-148	516.00
IUUC-Gac-042223	Gasterosteus aculeatus	71.57	6.00e-133	466.00
IUUC-Gma-042870	Glycine max	67.42	2.00e-100	358.00
IUUC-Ggo-045617	Gorilla gorilla	86.44	1.00e-153	535.00
IUUC-Hsa-046968	Homo sapiens	86.44	2.00e-153	534.00
IUUC-Hvu-047072	Hordeum vulgare	54.78	1.00e-81	295.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	72.95	4.00e-121	427.00
IUUC-Kpa-049093	Komagataella pastoris	57.47	2.00e-79	288.00
IUUC-Lch-050346	Latimeria chalumnae	77.29	8.00e-146	509.00
IUUC-Lpe-051466	Leersia perrieri	69.32	3.00e-107	380.00
IUUC-Lma-053006	Leptosphaeria maculans	58.17	2.00e-88	318.00
IUUC-Laf-053422	Loxodonta africana	87.46	5.00e-150	523.00
IUUC-Mcc-055245	Macaca mulatta	88.69	9.00e-152	528.00
IUUC-Mor-056952	Magnaporthe oryzae	57.62	1.00e-90	326.00
IUUC-Mpo-057605	Magnaporthe poae	57.04	1.00e-95	342.00
IUUC-Mtr-057726	Medicago truncatula	67.55	2.00e-106	378.00
IUUC-Mla-059174	Melampsora laricipopulina	64.09	2.00e-100	358.00
IUUC-Mga-059562	Meleagris gallopavo	72.76	2.00e-114	404.00
IUUC-Mvi-060305	Microbotryum violaceum	60.98	3.00e-93	334.00
IUUC-Mmr-061588	Microcebus murinus	82.43	9.00e-152	529.00
IUUC-Mdo-061914	Monodelphis domestica	92.58	6.00e-160	556.00
IUUC-Mmu-063288	Mus musculus	82.26	4.00e-152	530.00
IUUC-Mac-064969	Musa acuminata	66.31	3.00e-108	383.00
IUUC-Mpu-066855	Mustela putorius furo	85.57	4.00e-150	523.00
IUUC-Mlu-068046	Myotis lucifugus	82.89	6.00e-150	523.00
IUUC-Nfi-068527	Neosartorya fischeri	57.68	2.00e-86	311.00
IUUC-Ncr-068678	Neurospora crassa	57.65	2.00e-91	328.00
IUUC-Nle-069848	Nomascus leucogenys	86.78	8.00e-154	535.00
IUUC-Opr-070589	Ochotona princeps	85.02	4.00e-147	513.00
IUUC-Ont-071733	Oreochromis niloticus	76.43	2.00e-125	441.00
IUUC-Ocu-074063	Oryctolagus cuniculus	87.46	2.00e-150	524.00
IUUC-Oba-075264	Oryza barthii	66.43	3.00e-106	377.00
IUUC-Obr-076048	Oryza brachyantha	66.55	1.00e-106	378.00
IUUC-Ogl-077637	Oryza glaberrima	68.94	6.00e-106	376.00
IUUC-Ogu-078830	Oryza glumaepatula	66.43	2.00e-106	378.00
IUUC-Oin-079150	Oryza indica	66.43	1.00e-106	378.00
IUUC-Olo-080398	Oryza longistaminata	56.76	1.00e-83	301.00
IUUC-Ome-081544	Oryza meridionalis	57.52	7.00e-91	326.00
IUUC-Oni-082250	Oryza nivara	66.43	1.00e-106	378.00
IUUC-Opu-083638	Oryza punctata	66.07	2.00e-106	377.00
IUUC-Oru-084981	Oryza rufipogon	66.43	9.00e-107	379.00
IUUC-Osa-085961	Oryza sativa	66.43	9.00e-107	379.00
IUUC-Olu-087880	Ostreococcus lucimarinus	67.88	2.00e-111	394.00
IUUC-Oga-088891	Otolemur garnettii	91.04	2.00e-149	521.00
IUUC-Oar-090021	Ovis aries	85.53	3.00e-152	530.00
IUUC-Ptr-091458	Pan troglodytes	86.44	2.00e-153	534.00
IUUC-Pan-092546	Papio anubis	87.12	3.00e-154	536.00
IUUC-Psi-093280	Pelodiscus sinensis	92.45	4.00e-150	523.00
IUUC-Pma-094298	Petromyzon marinus	80.75	5.00e-126	442.00
IUUC-Pno-094847	Phaeosphaeria nodorum	60.15	8.00e-90	323.00
IUUC-Ppa-095855	Physcomitrella patens	64.62	7.00e-108	382.00
IUUC-Pfo-096428	Poecilia formosa	75.25	1.00e-128	452.00
IUUC-Pab-098696	Pongo abelii	86.44	8.00e-153	532.00
IUUC-Pop-099405	Populus trichocarpa	65.83	5.00e-107	379.00
IUUC-Pca-100740	Procavia capensis	88.53	6.00e-148	516.00
IUUC-Ppe-101854	Prunus persica	67.42	3.00e-107	380.00
IUUC-Pva-103212	Pteropus vampyrus	89.89	3.00e-149	520.00
IUUC-Pgr-103474	Puccinia graminis	64.77	8.00e-101	359.00
IUUC-Ptt-103933	Puccinia triticina	49.42	4.00e-62	230.00
IUUC-Pte-104089	Pyrenophora teres	52.30	6.00e-89	320.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	56.43	1.00e-88	318.00
IUUC-Rno-105057	Rattus norvegicus	83.23	4.00e-153	533.00
IUUC-Sha-107137	Sarcophilus harrisii	93.86	1.00e-159	555.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	58.60	3.00e-100	357.00
IUUC-Spo-108078	Schizosaccharomyces pombe	63.08	2.00e-101	361.00
IUUC-Smo-109288	Selaginella moellendorffii	67.75	2.00e-109	387.00
IUUC-Sit-110246	Setaria italica	65.95	4.00e-106	376.00
IUUC-Sly-111379	Solanum lycopersicum	66.91	2.00e-107	381.00
IUUC-Stu-112777	Solanum tuberosum	64.29	3.00e-107	380.00
IUUC-Sbi-114325	Sorghum bicolor	65.12	3.00e-106	377.00
IUUC-Sre-115203	Sporisorium reilianum	59.40	2.00e-81	295.00
IUUC-Ssc-115361	Sus scrofa	86.99	3.00e-151	527.00
IUUC-Tgu-116967	Taeniopygia guttata	90.11	4.00e-145	506.00
IUUC-Tru-117570	Takifugu rubripes	76.98	2.00e-133	468.00
IUUC-Tsy-119280	Tarsius syrichta	85.58	1.00e-109	389.00
IUUC-Tni-120721	Tetraodon nigroviridis	76.24	8.00e-133	466.00
IUUC-Tca-121494	Theobroma cacao	65.00	1.00e-107	381.00
IUUC-Tre-121869	Trichoderma reesei	57.44	5.00e-93	333.00
IUUC-Tvi-122510	Trichoderma virens	57.45	3.00e-92	331.00
IUUC-Tae-123071	Triticum aestivum	66.43	3.00e-106	377.00
IUUC-Tur-126240	Triticum urartu	66.43	9.00e-106	375.00
IUUC-Tme-126921	Tuber melanosporum	59.35	5.00e-96	343.00
IUUC-Tbe-127872	Tupaia belangeri	82.23	6.00e-138	483.00
IUUC-Ttr-129134	Tursiops truncatus	84.33	1.00e-150	525.00
IUUC-Uma-129412	Ustilago maydis	59.25	7.00e-79	287.00
IUUC-Vda-130003	Verticillium dahliae	55.24	3.00e-91	327.00
IUUC-Vvi-131272	Vitis vinifera	67.67	5.00e-107	379.00
IUUC-Xtr-132019	Xenopus tropicalis	77.55	3.00e-139	487.00
IUUC-Xma-134203	Xiphophorus maculatus	75.59	8.00e-135	473.00
IUUC-Yli-134503	Yarrowia lipolytica	55.00	5.00e-87	313.00
IUUC-Zma-135232	Zea mays	67.41	2.00e-105	374.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence