iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000060750.1	ENSRNOT00000084313.1	ENSRNOP00000069810.1
ENSRNOG00000060750.1	ENSRNOT00000082709.1	ENSRNOP00000069573.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
RAID2
Protein-protein Interaction
IID	HINT
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.60e-07	30.7	935	976

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg..plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iCl+ +++g  ++ lpC H+fh+ C+ +w        ++ +CP+Cr
   Q: 935  CTICLSILEEGedVRRLPCMHLFHQVCVDQW------LITNKKCPICR 976
           9*****9944444******************......**********8 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MTQWTPEYNE LYTLKVAMKS GTPPDAPTTQ ESLKAVLLHP QPLGATKSFP AEVEMINSKV 60
GNEFSHLCDD SQKQEKDMND NQQEQEKSGV VRKKRKSQQA GPSYVQNCVK ENQEILGLRQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGCGCAGT CGGGGAGGGC CGGCCCAGGC TGCGGCGGCG GCGGCGATGG TAGCGGGGCG 60
CTGGGGCTGC GCGGCGTAGA GACGCCGGCC GTTCAGGGTC GCGAGCGCGC GTGGGCCGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR029306--RNF111_N
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF15303--RNF111_N
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0043234--C:protein complex
GO:0046332--F:SMAD binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007389--P:pattern specification process
GO:0031398--P:positive regulation of protein ubiquitination
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0030511--P:positive regulation of transforming growth factor beta receptor signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030579--P:ubiquitin-dependent SMAD protein catabolic process

KEGG

rno:300813

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000605	Aegilops tauschii	50.94	1.00e-13	69.30
IUUC-Aml-001378	Ailuropoda melanoleuca	88.92	0.00e+00	1328.00
IUUC-Apl-003634	Anas platyrhynchos	77.89	0.00e+00	1181.00
IUUC-Aca-004574	Anolis carolinensis	73.94	1.00e-123	436.00
IUUC-Ath-007520	Arabidopsis thaliana	35.51	3.00e-15	75.50
IUUC-Acl-008067	Aspergillus clavatus	44.64	2.00e-10	61.20
IUUC-Ang-009544	Aspergillus niger	53.33	3.00e-10	60.80
IUUC-Ate-010250	Aspergillus terreus	51.11	7.00e-10	59.70
IUUC-Bta-012823	Bos taurus	88.93	0.00e+00	1355.00
IUUC-Bdi-014777	Brachypodium distachyon	59.09	4.00e-13	67.80
IUUC-Cja-018850	Callithrix jacchus	86.85	0.00e+00	1215.00
IUUC-Cfa-021062	Canis familiaris	89.12	0.00e+00	1326.00
IUUC-Cpo-021467	Cavia porcellus	83.99	0.00e+00	1253.00
IUUC-Csa-024048	Chlorocebus sabaeus	89.63	0.00e+00	1326.00
IUUC-Cho-024278	Choloepus hoffmanni	78.27	5.00e-120	425.00
IUUC-Dre-028323	Danio rerio	48.22	9.00e-150	524.00
IUUC-Dno-028850	Dasypus novemcinctus	83.61	0.00e+00	1222.00
IUUC-Dme-031973	Drosophila melanogaster	38.24	2.00e-25	111.00
IUUC-Ete-032985	Echinops telfairi	86.83	2.00e-112	400.00
IUUC-Eca-033659	Equus caballus	89.33	0.00e+00	1384.00
IUUC-Eeu-034773	Erinaceus europaeus	78.30	0.00e+00	681.00
IUUC-Fca-035560	Felis catus	88.82	0.00e+00	1285.00
IUUC-Fal-037598	Ficedula albicollis	76.98	0.00e+00	1179.00
IUUC-Gmo-038696	Gadus morhua	70.77	3.00e-66	246.00
IUUC-Gga-040900	Gallus gallus	78.99	0.00e+00	1176.00
IUUC-Gac-041830	Gasterosteus aculeatus	50.74	6.00e-167	581.00
IUUC-Gma-043396	Glycine max	50.00	7.00e-14	70.10
IUUC-Ggo-044921	Gorilla gorilla	89.23	0.00e+00	1398.00
IUUC-Hsa-046529	Homo sapiens	90.04	0.00e+00	1400.00
IUUC-Itr-048765	Ictidomys tridecemlineatus	91.04	0.00e+00	1322.00
IUUC-Lch-049512	Latimeria chalumnae	68.53	0.00e+00	935.00
IUUC-Lpe-050764	Leersia perrieri	52.94	1.00e-12	66.20
IUUC-Loc-052174	Lepisosteus oculatus	55.67	0.00e+00	663.00
IUUC-Laf-053804	Loxodonta africana	87.92	0.00e+00	1227.00
IUUC-Mcc-055297	Macaca mulatta	89.33	0.00e+00	1355.00
IUUC-Meu-056052	Macropus eugenii	79.94	2.00e-117	417.00
IUUC-Mtr-058136	Medicago truncatula	55.32	3.00e-13	67.80
IUUC-Mga-059350	Meleagris gallopavo	78.89	0.00e+00	1201.00
IUUC-Mmr-061666	Microcebus murinus	89.22	0.00e+00	1348.00
IUUC-Mdo-061958	Monodelphis domestica	82.46	0.00e+00	1239.00
IUUC-Mmu-063900	Mus musculus	96.26	0.00e+00	1437.00
IUUC-Mac-065281	Musa acuminata	31.71	8.00e-11	59.30
IUUC-Mpu-066492	Mustela putorius furo	88.42	0.00e+00	1324.00
IUUC-Mlu-067464	Myotis lucifugus	87.75	0.00e+00	1284.00
IUUC-Nfi-068528	Neosartorya fischeri	51.11	7.00e-10	59.30
IUUC-Nle-070038	Nomascus leucogenys	88.83	0.00e+00	1392.00
IUUC-Opr-070924	Ochotona princeps	80.14	0.00e+00	767.00
IUUC-Ont-072297	Oreochromis niloticus	52.75	5.00e-100	359.00
IUUC-Oan-072897	Ornithorhynchus anatinus	62.63	0.00e+00	808.00
IUUC-Ocu-074713	Oryctolagus cuniculus	88.12	0.00e+00	1340.00
IUUC-Oba-074994	Oryza barthii	32.46	6.00e-13	69.30
IUUC-Obr-076337	Oryza brachyantha	32.11	4.00e-13	69.70
IUUC-Ogl-077817	Oryza glaberrima	32.46	6.00e-13	69.30
IUUC-Ogu-077954	Oryza glumaepatula	32.46	6.00e-13	68.90
IUUC-Oin-079127	Oryza indica	34.62	8.00e-13	68.90
IUUC-Olo-080304	Oryza longistaminata	32.46	6.00e-13	68.90
IUUC-Ome-081451	Oryza meridionalis	34.62	9.00e-13	68.90
IUUC-Oni-082765	Oryza nivara	32.46	6.00e-13	68.90
IUUC-Opu-084108	Oryza punctata	34.62	6.00e-13	69.30
IUUC-Oru-084289	Oryza rufipogon	32.46	6.00e-13	68.90
IUUC-Osa-085712	Oryza sativa	32.46	7.00e-13	68.90
IUUC-Ola-087455	Oryzias latipes	50.00	7.00e-174	604.00
IUUC-Oga-088809	Otolemur garnettii	89.46	0.00e+00	1402.00
IUUC-Oar-090286	Ovis aries	87.83	0.00e+00	1358.00
IUUC-Ptr-091451	Pan troglodytes	89.23	0.00e+00	1393.00
IUUC-Pan-092593	Papio anubis	89.95	0.00e+00	1341.00
IUUC-Psi-093662	Pelodiscus sinensis	76.83	0.00e+00	1139.00
IUUC-Pfo-096611	Poecilia formosa	49.52	3.00e-170	592.00
IUUC-Pab-097885	Pongo abelii	88.83	0.00e+00	1356.00
IUUC-Pca-100561	Procavia capensis	77.07	0.00e+00	676.00
IUUC-Pva-102891	Pteropus vampyrus	88.94	0.00e+00	1416.00
IUUC-Sha-107401	Sarcophilus harrisii	82.74	0.00e+00	1246.00
IUUC-Sit-109909	Setaria italica	50.00	7.00e-14	70.50
IUUC-Sar-113238	Sorex araneus	80.56	0.00e+00	781.00
IUUC-Sbi-114185	Sorghum bicolor	50.94	5.00e-14	70.50
IUUC-Ssc-116436	Sus scrofa	88.84	0.00e+00	1367.00
IUUC-Tgu-116470	Taeniopygia guttata	77.35	0.00e+00	1121.00
IUUC-Tru-118054	Takifugu rubripes	47.70	5.00e-155	541.00
IUUC-Tni-120063	Tetraodon nigroviridis	49.07	1.00e-170	593.00
IUUC-Tae-125027	Triticum aestivum	58.33	2.00e-14	72.40
IUUC-Tur-126415	Triticum urartu	53.70	2.00e-13	68.20
IUUC-Tbe-128026	Tupaia belangeri	83.35	0.00e+00	1136.00
IUUC-Ttr-128623	Tursiops truncatus	85.51	0.00e+00	1263.00
IUUC-Uma-129481	Ustilago maydis	35.53	5.00e-10	61.20
IUUC-Vpa-130662	Vicugna pacos	85.40	0.00e+00	1337.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence