iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000011057.4	ENSCAFT00000017612.4	ENSCAFP00000016308.3
ENSCAFG00000011057.4	ENSCAFT00000017607.3	ENSCAFP00000016303.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.80e-06	28.7	7	50

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf...kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC + f   +d +    CgH+fh++Cl +w     ++ ++ +CP Cr
   Q: 7    CTICSDFFdhsRD-VAAIHCGHTFHLQCLIQW----FETAPSRTCPQCR 50
           9***776655344.88999*************....9***********8 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MPIRALCTIC SDFFDHSRDV AAIHCGHTFH LQCLIQWFET APSRTCPQCR IQVGRRTIIN 60
KLFFDLAQEE ENVLDAEFLK NELDNTRAQL SLKEKEKKDS QAIIDTLRDT LEERNATVES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTATCC GTGCGCTGTG CACCATCTGC TCCGACTTCT TCGACCACTC CCGAGATGTG 60
GCCGCCATCC ACTGCGGCCA CACCTTCCAT CTGCAGTGGT GAGTGACCGC AGTGGCGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005057--F:signal transducer activity, downstream of receptor
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032688--P:negative regulation of interferon-beta production
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001411	Ailuropoda melanoleuca	87.04	0.00e+00	785.00
IUUC-Atr-002646	Amborella trichopoda	36.36	2.00e-06	47.40
IUUC-Apl-003777	Anas platyrhynchos	56.06	5.00e-108	384.00
IUUC-Aca-004476	Anolis carolinensis	55.84	1.00e-141	496.00
IUUC-Ame-011706	Astyanax mexicanus	40.51	1.00e-08	50.80
IUUC-Bta-013084	Bos taurus	84.50	0.00e+00	794.00
IUUC-Cel-018227	Caenorhabditis elegans	24.67	5.00e-13	68.90
IUUC-Cja-019856	Callithrix jacchus	85.29	0.00e+00	791.00
IUUC-Cpo-022481	Cavia porcellus	81.91	0.00e+00	775.00
IUUC-Csa-023793	Chlorocebus sabaeus	84.65	0.00e+00	813.00
IUUC-Csv-026190	Ciona savignyi	31.72	9.00e-40	157.00
IUUC-Dre-027984	Danio rerio	48.44	3.00e-121	428.00
IUUC-Dno-029478	Dasypus novemcinctus	83.76	0.00e+00	792.00
IUUC-Dor-030526	Dipodomys ordii	61.28	3.00e-160	558.00
IUUC-Dme-032130	Drosophila melanogaster	29.70	5.00e-22	98.60
IUUC-Ete-033012	Echinops telfairi	89.46	7.00e-149	520.00
IUUC-Eca-034084	Equus caballus	89.77	0.00e+00	873.00
IUUC-Eeu-034579	Erinaceus europaeus	76.05	0.00e+00	627.00
IUUC-Fca-035772	Felis catus	91.47	0.00e+00	859.00
IUUC-Fal-037098	Ficedula albicollis	58.39	6.00e-138	483.00
IUUC-Gmo-038704	Gadus morhua	47.75	1.00e-110	393.00
IUUC-Gga-041109	Gallus gallus	53.23	5.00e-136	477.00
IUUC-Gac-042636	Gasterosteus aculeatus	46.64	4.00e-116	411.00
IUUC-Ggo-045184	Gorilla gorilla	84.65	0.00e+00	808.00
IUUC-Hsa-046651	Homo sapiens	84.65	0.00e+00	780.00
IUUC-Itr-048550	Ictidomys tridecemlineatus	83.80	0.00e+00	816.00
IUUC-Lch-049575	Latimeria chalumnae	55.37	8.00e-133	466.00
IUUC-Loc-051999	Lepisosteus oculatus	50.45	1.00e-120	426.00
IUUC-Lma-053133	Leptosphaeria maculans	43.86	3.00e-08	52.00
IUUC-Laf-053347	Loxodonta africana	84.40	0.00e+00	805.00
IUUC-Mcc-054668	Macaca mulatta	77.66	2.00e-86	311.00
IUUC-Meu-056862	Macropus eugenii	62.55	3.00e-162	565.00
IUUC-Mga-059443	Meleagris gallopavo	55.95	2.00e-111	395.00
IUUC-Mmr-061219	Microcebus murinus	80.64	0.00e+00	758.00
IUUC-Mdo-062103	Monodelphis domestica	69.44	0.00e+00	647.00
IUUC-Mmu-064005	Mus musculus	77.56	0.00e+00	737.00
IUUC-Mpu-066570	Mustela putorius furo	90.83	0.00e+00	858.00
IUUC-Mlu-067806	Myotis lucifugus	85.56	0.00e+00	810.00
IUUC-Nle-069123	Nomascus leucogenys	85.29	0.00e+00	800.00
IUUC-Opr-071063	Ochotona princeps	82.30	0.00e+00	800.00
IUUC-Ont-071973	Oreochromis niloticus	49.26	2.00e-121	429.00
IUUC-Oan-073278	Ornithorhynchus anatinus	69.63	1.00e-98	352.00
IUUC-Ocu-074582	Oryctolagus cuniculus	78.78	0.00e+00	726.00
IUUC-Ola-086959	Oryzias latipes	47.36	1.00e-107	382.00
IUUC-Oga-088807	Otolemur garnettii	82.20	0.00e+00	751.00
IUUC-Oar-089273	Ovis aries	80.08	0.00e+00	763.00
IUUC-Ptr-090768	Pan troglodytes	84.86	0.00e+00	811.00
IUUC-Pan-091880	Papio anubis	84.86	0.00e+00	813.00
IUUC-Psi-093782	Pelodiscus sinensis	62.10	2.00e-137	482.00
IUUC-Pma-094365	Petromyzon marinus	39.63	1.00e-69	256.00
IUUC-Ppa-095896	Physcomitrella patens	25.34	7.00e-07	49.30
IUUC-Pfo-096068	Poecilia formosa	47.97	9.00e-112	397.00
IUUC-Pab-098063	Pongo abelii	83.62	0.00e+00	786.00
IUUC-Pca-100327	Procavia capensis	86.46	5.00e-174	603.00
IUUC-Pva-102924	Pteropus vampyrus	87.42	0.00e+00	816.00
IUUC-Pgr-103587	Puccinia graminis	26.46	1.00e-06	47.80
IUUC-Ptt-103972	Puccinia triticina	30.58	7.00e-06	45.40
IUUC-Pte-104366	Pyrenophora teres	30.00	8.00e-08	50.80
IUUC-Rno-105799	Rattus norvegicus	80.34	0.00e+00	758.00
IUUC-Sha-107643	Sarcophilus harrisii	66.44	3.00e-163	567.00
IUUC-Sit-109687	Setaria italica	36.23	1.00e-06	48.50
IUUC-Sar-113187	Sorex araneus	79.15	0.00e+00	696.00
IUUC-Sbi-114760	Sorghum bicolor	36.23	1.00e-06	48.50
IUUC-Sre-115057	Sporisorium reilianum	35.71	4.00e-06	46.60
IUUC-Ssc-115838	Sus scrofa	88.73	4.00e-145	506.00
IUUC-Tgu-116674	Taeniopygia guttata	58.88	9.00e-132	463.00
IUUC-Tru-117753	Takifugu rubripes	44.26	6.00e-111	394.00
IUUC-Tsy-119416	Tarsius syrichta	67.82	1.00e-61	230.00
IUUC-Tni-120767	Tetraodon nigroviridis	47.13	8.00e-114	404.00
IUUC-Tbe-128001	Tupaia belangeri	48.32	4.00e-80	291.00
IUUC-Ttr-128687	Tursiops truncatus	88.54	0.00e+00	856.00
IUUC-Uma-129349	Ustilago maydis	39.29	1.00e-05	45.10
IUUC-Xtr-131905	Xenopus tropicalis	54.03	3.00e-140	491.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence