iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.50e-06	29.0	20	75
E3 activity/RING/RING	1.20e-07	33.0	23	64

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwl..asggktcPvtrqplteedlvPn 58
            f C I l+l +dP v+ +G+ +   ++ kwl   s+ k cPv+++ ++e+ lvP 
   Q: 20   NFECNICLDLAQDPIVTLCGHLFCWPCLYKWLhlHSQSKDCPVCKAVIEEDRLVPL 75
           79******************************87777779**************96 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iCl+  +d p+v+ CgH+f+  Cl+kw    ++ s++  CP+C+
   Q: 23   CNICLDLAQD-PIVTLCGHLFCWPCLYKW---LHLHSQSKDCPVCK 64
           99********.999***************...334577777****7 PP

Organism

Arabidopsis thaliana

Protein Sequence
(Fasta)

MSDVPSCSSG NDTNNNDSSN FECNICLDLA QDPIVTLCGH LFCWPCLYKW LHLHSQSKDC 60
PVCKAVIEED RLVPLYGRGK SSADPRSKSI PGLEVPNRPS GQRPETAQPP DPNHGFAHHH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TACAAATATT AATATTCTGA AAATATCTTT CTCTCGATGA AACTTGTCTC CTCCGGCCAA 60
CCTTAACCCT TAAGCGAACG GTGTTCCTTT GCGGATTGCG ATCGTTCCGT CGATCCCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0016021--C:integral component of membrane
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0044390--F:ubiquitin-like protein conjugating enzyme binding
GO:0008270--F:zinc ion binding
GO:0071712--P:ER-associated misfolded protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

ath:AT1G19310

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001042	Aegilops tauschii	59.86	4.00e-39	154.00
IUUC-Atr-002444	Amborella trichopoda	66.05	3.00e-53	200.00
IUUC-Apl-003744	Anas platyrhynchos	58.57	7.00e-23	98.20
IUUC-Aly-006065	Arabidopsis lyrata	97.61	5.00e-95	339.00
IUUC-Ame-011316	Astyanax mexicanus	54.64	3.00e-26	110.00
IUUC-Bdi-014183	Brachypodium distachyon	66.44	1.00e-51	195.00
IUUC-Bol-015663	Brassica oleracea	85.31	2.00e-75	274.00
IUUC-Bra-017113	Brassica rapa	86.73	3.00e-86	310.00
IUUC-Cre-022829	Chlamydomonas reinhardtii	55.29	3.00e-25	105.00
IUUC-Cin-025421	Ciona intestinalis	34.15	4.00e-08	52.80
IUUC-Dre-028094	Danio rerio	57.14	3.00e-22	97.40
IUUC-Dme-031966	Drosophila melanogaster	54.65	1.00e-25	109.00
IUUC-Eeu-034614	Erinaceus europaeus	48.57	2.00e-15	74.70
IUUC-Gma-043172	Glycine max	69.15	5.00e-68	249.00
IUUC-Hvu-047043	Hordeum vulgare	66.00	4.00e-50	190.00
IUUC-Lpe-050836	Leersia perrieri	62.42	1.00e-51	197.00
IUUC-Mor-057077	Magnaporthe oryzae	42.11	2.00e-08	52.80
IUUC-Mtr-058130	Medicago truncatula	61.26	7.00e-59	219.00
IUUC-Mac-065053	Musa acuminata	64.10	1.00e-54	205.00
IUUC-Ont-072482	Oreochromis niloticus	56.98	7.00e-26	109.00
IUUC-Obr-076382	Oryza brachyantha	61.78	3.00e-47	180.00
IUUC-Ogl-077553	Oryza glaberrima	63.31	7.00e-46	176.00
IUUC-Ogu-078463	Oryza glumaepatula	62.59	6.00e-45	172.00
IUUC-Oin-080177	Oryza indica	63.31	7.00e-46	176.00
IUUC-Olo-080378	Oryza longistaminata	63.76	3.00e-52	197.00
IUUC-Ome-081605	Oryza meridionalis	62.59	9.00e-41	159.00
IUUC-Oni-082458	Oryza nivara	63.31	2.00e-45	176.00
IUUC-Opu-083362	Oryza punctata	61.87	1.00e-44	172.00
IUUC-Oru-084757	Oryza rufipogon	64.03	2.00e-45	174.00
IUUC-Osa-086198	Oryza sativa	64.03	2.00e-45	174.00
IUUC-Ola-086507	Oryzias latipes	55.81	4.00e-26	110.00
IUUC-Pfo-096818	Poecilia formosa	55.81	2.00e-25	108.00
IUUC-Pop-098889	Populus trichocarpa	72.22	3.00e-66	243.00
IUUC-Ppe-101752	Prunus persica	69.15	3.00e-72	264.00
IUUC-Smo-109663	Selaginella moellendorffii	48.78	1.00e-32	130.00
IUUC-Sit-110376	Setaria italica	55.80	1.00e-47	182.00
IUUC-Sly-111255	Solanum lycopersicum	57.51	3.00e-49	187.00
IUUC-Stu-112117	Solanum tuberosum	56.77	1.00e-48	185.00
IUUC-Sbi-114116	Sorghum bicolor	62.67	2.00e-50	191.00
IUUC-Tca-121264	Theobroma cacao	76.32	1.00e-65	242.00
IUUC-Tae-124257	Triticum aestivum	66.67	6.00e-51	192.00
IUUC-Tur-126443	Triticum urartu	66.67	6.00e-51	192.00
IUUC-Vda-129983	Verticillium dahliae	45.28	6.00e-09	53.10
IUUC-Vvi-131449	Vitis vinifera	71.05	2.00e-74	270.00
IUUC-Xma-134225	Xiphophorus maculatus	55.81	1.00e-25	108.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence