iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-063045

UUCD1 version

UUC-MoD-00991

Ensembl Protein ID

ENSMODP00000041213.1

UniProt Accession

K7E611; K7E611_MONDO

Protein Name

Uncharacterized protein

Gene Name

RNF145

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000008093.3	ENSMODT00000044322.1	ENSMODP00000041213.1
ENSMODG00000008093.3	ENSMODT00000010257.3	ENSMODP00000010063.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.30e-08	34.6	537	577

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf...kdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           CaiC+++    k   +++pC H+fha Cl+kw       + + +CPlC
   Q: 537  CAICYQEKqdmKS-AVITPCSHFFHAGCLKKW------LYVQETCPLC 577
           ****985534144.888***************......********** PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAAREKLEAV LNVALRVPSI MLLDVLYRWD VSSFFQQIQR SSLNNNPLFQ YKYLALNMHY 60
VGYILSVVLL TLPRQHLVQL YLYFLTALLL YAGHQISRDY VRSELESAYE GPMYLEPLSM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGTTGGAA CCAGGGGGGG AGGGAGGGAG GCGGGAGCCG CCGCTGCCGC CGCCGCCGCC 60
GCCGCAGAGC CTGGAGGGGG AGGGGGAGGG GGGAAAACGG GAGGGAGCCA GTGAGCGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR025754--TRC8_N_dom
IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13705--TRC8_N
PF13639--zf-RING_2

SMART

SM00184--RING
SM00744--RINGv

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002354	Ailuropoda melanoleuca	92.16	0.00e+00	1148.00
IUUC-Apl-003823	Anas platyrhynchos	91.55	0.00e+00	1127.00
IUUC-Aca-004944	Anolis carolinensis	92.38	0.00e+00	1111.00
IUUC-Ame-011578	Astyanax mexicanus	88.85	0.00e+00	1008.00
IUUC-Bta-012560	Bos taurus	86.22	0.00e+00	1125.00
IUUC-Cel-018539	Caenorhabditis elegans	27.85	5.00e-62	232.00
IUUC-Cja-018929	Callithrix jacchus	91.63	0.00e+00	1136.00
IUUC-Cfa-021110	Canis familiaris	91.08	0.00e+00	1155.00
IUUC-Cpo-022452	Cavia porcellus	92.82	0.00e+00	1140.00
IUUC-Csa-024116	Chlorocebus sabaeus	92.69	0.00e+00	1153.00
IUUC-Csv-025845	Ciona savignyi	39.88	5.00e-31	126.00
IUUC-Cme-027308	Cyanidioschyzon merolae	34.88	4.00e-09	57.00
IUUC-Dre-027493	Danio rerio	81.83	0.00e+00	1017.00
IUUC-Dno-029615	Dasypus novemcinctus	92.72	0.00e+00	1181.00
IUUC-Ete-032551	Echinops telfairi	70.20	0.00e+00	811.00
IUUC-Eca-033349	Equus caballus	96.33	0.00e+00	1118.00
IUUC-Eeu-035349	Erinaceus europaeus	97.07	0.00e+00	706.00
IUUC-Fca-035696	Felis catus	91.38	0.00e+00	1163.00
IUUC-Fal-037495	Ficedula albicollis	90.56	0.00e+00	1101.00
IUUC-Gmo-039374	Gadus morhua	85.25	0.00e+00	1007.00
IUUC-Gga-040146	Gallus gallus	90.78	0.00e+00	1115.00
IUUC-Gac-041731	Gasterosteus aculeatus	83.02	0.00e+00	1018.00
IUUC-Ggo-045158	Gorilla gorilla	92.63	0.00e+00	1139.00
IUUC-Hsa-045787	Homo sapiens	92.69	0.00e+00	1150.00
IUUC-Itr-048928	Ictidomys tridecemlineatus	91.56	0.00e+00	1037.00
IUUC-Lch-050499	Latimeria chalumnae	91.65	0.00e+00	1053.00
IUUC-Loc-052482	Lepisosteus oculatus	90.43	0.00e+00	1039.00
IUUC-Laf-053362	Loxodonta africana	92.79	0.00e+00	1159.00
IUUC-Mcc-055779	Macaca mulatta	92.78	0.00e+00	1141.00
IUUC-Meu-056130	Macropus eugenii	80.36	4.00e-167	581.00
IUUC-Mga-059742	Meleagris gallopavo	90.48	0.00e+00	1109.00
IUUC-Mmr-060812	Microcebus murinus	92.16	0.00e+00	1158.00
IUUC-Mmu-064377	Mus musculus	91.55	0.00e+00	1159.00
IUUC-Mpu-066637	Mustela putorius furo	91.53	0.00e+00	1160.00
IUUC-Mlu-066985	Myotis lucifugus	93.98	0.00e+00	1153.00
IUUC-Nle-069833	Nomascus leucogenys	92.93	0.00e+00	1144.00
IUUC-Opr-070210	Ochotona princeps	81.34	4.00e-128	451.00
IUUC-Ont-072116	Oreochromis niloticus	83.93	0.00e+00	1035.00
IUUC-Oan-073730	Ornithorhynchus anatinus	89.78	0.00e+00	1147.00
IUUC-Ocu-074958	Oryctolagus cuniculus	92.77	0.00e+00	1138.00
IUUC-Ola-087368	Oryzias latipes	88.34	0.00e+00	1015.00
IUUC-Oga-088301	Otolemur garnettii	91.90	0.00e+00	1140.00
IUUC-Oar-089745	Ovis aries	90.77	0.00e+00	1145.00
IUUC-Ptr-091397	Pan troglodytes	92.54	0.00e+00	1149.00
IUUC-Pan-092817	Papio anubis	92.69	0.00e+00	1153.00
IUUC-Psi-093820	Pelodiscus sinensis	88.35	0.00e+00	1082.00
IUUC-Pma-094457	Petromyzon marinus	66.67	6.00e-171	593.00
IUUC-Pfo-097173	Poecilia formosa	82.09	0.00e+00	1026.00
IUUC-Pab-097630	Pongo abelii	93.23	0.00e+00	1147.00
IUUC-Pca-100472	Procavia capensis	91.78	0.00e+00	1124.00
IUUC-Pva-102485	Pteropus vampyrus	92.53	0.00e+00	1077.00
IUUC-Rno-106029	Rattus norvegicus	93.22	0.00e+00	1115.00
IUUC-Sce-106438	Saccharomyces cerevisiae	33.87	2.00e-06	47.80
IUUC-Sha-106580	Sarcophilus harrisii	95.65	0.00e+00	1253.00
IUUC-Sit-109816	Setaria italica	38.46	1.00e-10	58.90
IUUC-Ssc-116438	Sus scrofa	89.21	0.00e+00	1022.00
IUUC-Tgu-116638	Taeniopygia guttata	90.53	0.00e+00	1095.00
IUUC-Tru-117779	Takifugu rubripes	84.71	0.00e+00	1037.00
IUUC-Tsy-119541	Tarsius syrichta	90.87	0.00e+00	1086.00
IUUC-Tni-119862	Tetraodon nigroviridis	85.37	0.00e+00	1034.00
IUUC-Tbe-127328	Tupaia belangeri	86.24	0.00e+00	1004.00
IUUC-Ttr-129066	Tursiops truncatus	95.33	5.00e-180	624.00
IUUC-Xtr-132826	Xenopus tropicalis	83.50	0.00e+00	1090.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence