iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.80e-28	97.2	814	850

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf....sdtllvsGsdDgtikvWDlrtgvl 35
           H+ + ++++f    + t l+sGsdD+++k+W++ + ++
   Q: 814  HEKRAWSVDFseacP-TKLASGSDDCSVKLWNINERNC 850
           888899****99655.9***************866665 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Involved in suppression of photomorphogenesis in dark-grown seedlings. Probably part of the COP1/SPA E3 ubiquitin-protein ligase complex.

Protein Sequence
(Fasta)

MMDEGSVGDV SRIDEADVAH LQFKNSEQSF KPENIEVREV KEVQVQREAG SPDCSYGVIA 60
DFLDGKNGGD HVELIGNEPC SSRQNTNDEG DVVEELTVKT CEGSSMAIVG RPSSRARLEM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTACTTAAA CACAGTCAAA TTCATTTTCT GCCTTAGAAA AGATTTTTAT CGAAAATCGA 60
CGTTTTTGAA AAAACTCAAA TTATCGTCGT TTTGTTCTCA GATTTCTTCT GCTCTCTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0607--Phytochrome signaling pathway
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004672--F:protein kinase activity
GO:0009585--P:red, far-red light phototransduction

KEGG

ath:AT4G11110

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005954	Arabidopsis lyrata	94.79	0.00e+00	1945.00
IUUC-Bol-015237	Brassica oleracea	80.21	0.00e+00	1556.00
IUUC-Bra-017767	Brassica rapa	78.41	0.00e+00	1496.00
IUUC-Cho-024883	Choloepus hoffmanni	32.91	4.00e-41	162.00
IUUC-Gma-044276	Glycine max	51.16	0.00e+00	909.00
IUUC-Mtr-058593	Medicago truncatula	48.06	0.00e+00	874.00
IUUC-Pop-098964	Populus trichocarpa	50.46	0.00e+00	1002.00
IUUC-Ppe-101771	Prunus persica	50.78	0.00e+00	974.00
IUUC-Sit-110269	Setaria italica	48.57	0.00e+00	761.00
IUUC-Sly-111360	Solanum lycopersicum	45.00	0.00e+00	815.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence