iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000002867.1	ENSTGUT00000002984.1	ENSTGUP00000002955.1
ENSTGUG00000002867.1	ENSTGUT00000002985.1	ENSTGUP00000002956.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.30e-06	28.6	24	66
E3 activity/RING/U-box	1.10e-07	31.7	20	86

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl+  ++ p+++ C H+f++ C  k+ ++k  +++   CPlC+
   Q: 24   CPICLDVVQE-PVSTKCDHTFCRFCMFKLINKK--KKGVVECPLCK 66
           ********99.**************84443444..99999*****6 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk...tcPvtrqplteedlvPnltlrrliqa 67
           + + CpI l++ ++Pv +++ +t+ r ++ k +++++k   +cP++++++t+++l+ n   ++li+ 
   Q: 20   KNLECPICLDVVQEPVSTKCDHTFCRFCMFKLINKKKKgvvECPLCKTEVTKRSLKENSRFKQLIEG 86
           5688*************************************************************86 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MDFSVITIGQ VQNVLSAMQK NLECPICLDV VQEPVSTKCD HTFCRFCMFK LINKKKKGVV 60
ECPLCKTEVT KRSLKENSRF KQLIEGLLEA IHAFELDTGV KFLKNHHFPK TSTEATAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACTTCT CAGTAATTAC TATTGGACAA GTACAAAATG TGCTTTCAGC TATGCAGAAG 60
AATTTGGAGT GCCCAATATG GTATGTCAGG AAGTAATATC AGTACAGTTA GTTCTTTAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011364--BRCA1
IPR031099--BRCA1-associated
IPR025994--BRCA1_serine_dom
IPR001357--BRCT_dom
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50172--BRCT
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00533--BRCT
PF12820--BRCT_assoc
PF00097--zf-C3HC4

PRINTS

PR00493--BRSTCANCERI

SMART

SM00292--BRCT
SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006281--P:DNA repair

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002388	Ailuropoda melanoleuca	33.19	2.00e-93	338.00
IUUC-Apl-003252	Anas platyrhynchos	54.90	0.00e+00	1293.00
IUUC-Aca-004526	Anolis carolinensis	41.68	2.00e-112	399.00
IUUC-Ame-011720	Astyanax mexicanus	50.74	5.00e-57	216.00
IUUC-Bta-013433	Bos taurus	31.72	5.00e-85	310.00
IUUC-Bol-016476	Brassica oleracea	29.11	6.00e-18	85.90
IUUC-Cel-018208	Caenorhabditis elegans	29.21	3.00e-10	60.10
IUUC-Cja-019149	Callithrix jacchus	61.79	3.00e-76	280.00
IUUC-Cfa-020322	Canis familiaris	31.43	2.00e-83	304.00
IUUC-Cpo-021583	Cavia porcellus	55.36	1.00e-74	275.00
IUUC-Cre-022597	Chlamydomonas reinhardtii	35.21	1.00e-09	57.00
IUUC-Csa-024227	Chlorocebus sabaeus	48.56	3.00e-53	202.00
IUUC-Cho-024530	Choloepus hoffmanni	63.75	3.00e-62	234.00
IUUC-Cin-025364	Ciona intestinalis	41.38	8.00e-15	73.90
IUUC-Csv-026245	Ciona savignyi	41.77	3.00e-13	68.20
IUUC-Dno-029247	Dasypus novemcinctus	27.47	1.00e-55	212.00
IUUC-Ete-032472	Echinops telfairi	42.81	8.00e-58	219.00
IUUC-Eca-033446	Equus caballus	32.68	8.00e-94	338.00
IUUC-Eeu-034858	Erinaceus europaeus	47.94	2.00e-45	178.00
IUUC-Fca-035991	Felis catus	30.92	5.00e-110	393.00
IUUC-Fal-036803	Ficedula albicollis	78.95	0.00e+00	2671.00
IUUC-Gmo-038782	Gadus morhua	45.36	3.00e-44	173.00
IUUC-Gga-040969	Gallus gallus	59.11	0.00e+00	1775.00
IUUC-Gac-042296	Gasterosteus aculeatus	46.12	3.00e-52	200.00
IUUC-Ggo-044740	Gorilla gorilla	29.58	2.00e-104	374.00
IUUC-Hsa-046086	Homo sapiens	53.14	9.00e-73	269.00
IUUC-Itr-048512	Ictidomys tridecemlineatus	30.65	4.00e-88	320.00
IUUC-Kpa-049392	Komagataella pastoris	32.00	4.00e-07	48.10
IUUC-Lch-049789	Latimeria chalumnae	61.09	6.00e-83	303.00
IUUC-Lpe-050895	Leersia perrieri	28.11	2.00e-15	77.80
IUUC-Loc-051952	Lepisosteus oculatus	43.88	3.00e-82	300.00
IUUC-Laf-053648	Loxodonta africana	31.36	7.00e-89	322.00
IUUC-Mcc-055210	Macaca mulatta	30.12	4.00e-111	396.00
IUUC-Meu-056342	Macropus eugenii	49.08	6.00e-42	166.00
IUUC-Mga-060163	Meleagris gallopavo	54.56	0.00e+00	1270.00
IUUC-Mmr-061402	Microcebus murinus	29.14	5.00e-37	148.00
IUUC-Mdo-062209	Monodelphis domestica	32.33	5.00e-106	379.00
IUUC-Mmu-064003	Mus musculus	31.72	6.00e-79	289.00
IUUC-Mpu-065825	Mustela putorius furo	61.06	1.00e-77	283.00
IUUC-Mlu-068176	Myotis lucifugus	31.26	2.00e-76	281.00
IUUC-Nle-069178	Nomascus leucogenys	29.97	3.00e-106	380.00
IUUC-Opr-070574	Ochotona princeps	30.55	8.00e-62	233.00
IUUC-Ont-072380	Oreochromis niloticus	50.23	1.00e-59	225.00
IUUC-Oan-073243	Ornithorhynchus anatinus	59.30	7.00e-28	115.00
IUUC-Ocu-074424	Oryctolagus cuniculus	33.08	3.00e-84	307.00
IUUC-Ola-086863	Oryzias latipes	46.46	2.00e-54	207.00
IUUC-Oar-089938	Ovis aries	31.99	7.00e-84	306.00
IUUC-Ptr-090960	Pan troglodytes	30.35	3.00e-106	380.00
IUUC-Pan-092609	Papio anubis	28.76	9.00e-86	312.00
IUUC-Psi-093889	Pelodiscus sinensis	39.31	6.00e-124	438.00
IUUC-Pfo-096328	Poecilia formosa	39.24	6.00e-59	222.00
IUUC-Pab-097982	Pongo abelii	30.62	4.00e-113	403.00
IUUC-Pca-100698	Procavia capensis	52.22	4.00e-76	280.00
IUUC-Pva-102631	Pteropus vampyrus	32.66	6.00e-79	289.00
IUUC-Ptt-103843	Puccinia triticina	33.33	4.00e-07	48.90
IUUC-Rno-105879	Rattus norvegicus	31.22	5.00e-71	263.00
IUUC-Sha-106701	Sarcophilus harrisii	77.94	4.00e-28	120.00
IUUC-Sit-110609	Setaria italica	25.78	2.00e-16	81.30
IUUC-Sar-113047	Sorex araneus	31.38	1.00e-69	258.00
IUUC-Ssc-115846	Sus scrofa	31.83	2.00e-91	331.00
IUUC-Tru-117895	Takifugu rubripes	37.26	8.00e-57	215.00
IUUC-Tsy-118885	Tarsius syrichta	49.36	2.00e-38	154.00
IUUC-Tni-119654	Tetraodon nigroviridis	32.70	3.00e-47	184.00
IUUC-Tbe-127421	Tupaia belangeri	54.32	9.00e-49	189.00
IUUC-Ttr-128685	Tursiops truncatus	29.68	1.00e-91	331.00
IUUC-Vpa-130216	Vicugna pacos	61.61	5.00e-79	290.00
IUUC-Xtr-132398	Xenopus tropicalis	55.14	5.00e-63	236.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence