iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-090902

Ensembl Protein ID

ENSPTRP00000018591.5

UniProt Accession

H2QG38; H2QG38_PANTR

Genbank Protein ID

ENSPTRP00000018591

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

AACZ03117190

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000010858.5	ENSPTRT00000020104.5	ENSPTRP00000018591.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.80e-30	103.3	1133	1186

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCrsk 54
           k+C+vCg++g+++k+l+eCe+Cr+++HpaCl++s ++++ ++++  wiC+ C ++
   Q: 1133 KFCHVCGRKGRGSKHLLECERCRHAYHPACLGPS-YPTRATRKRrhWICSACVRC 1186
           58********************************.88888877777******876 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

GESDEEFQGF HSDEDVAPSS LRSALRSQRG RAPRGRGRKH KTTPLPPPRL ADVAPTPPKT 60
PARKRGEEGT ERMVQALTEL LRRAQAPQAP RSRACEPSTP RRSRGRPPGR PAGPCRRKQQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGAATCCG ACGAGTAGGT GAGGCTTTTG GAGGCGTCCC CGGAGCCGGG TGGGGCGGAG 60
GCCGGGTCTT CCAGGGGTTT GGGTTGTCCC GGGGGCGGCG TGGGCAGGCC GGGTCCTCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
PF02008--zf-CXXC

SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00317--SET

Gene Ontology

GO:0035097--C:histone methyltransferase complex
GO:0003677--F:DNA binding
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0008270--F:zinc ion binding
GO:0016458--P:gene silencing
GO:0080182--P:histone H3-K4 trimethylation
GO:0007613--P:memory
GO:0009994--P:oocyte differentiation
GO:0001541--P:ovarian follicle development
GO:0030728--P:ovulation
GO:0051569--P:regulation of histone H3-K4 methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002367	Ailuropoda melanoleuca	91.86	0.00e+00	3216.00
IUUC-Aca-004718	Anolis carolinensis	63.94	0.00e+00	1382.00
IUUC-Ame-011927	Astyanax mexicanus	44.65	0.00e+00	856.00
IUUC-Bta-013578	Bos taurus	93.57	0.00e+00	2932.00
IUUC-Bdi-014882	Brachypodium distachyon	33.50	2.00e-27	117.00
IUUC-Bra-017422	Brassica rapa	33.50	1.00e-27	118.00
IUUC-Cja-019138	Callithrix jacchus	94.20	0.00e+00	3362.00
IUUC-Cfa-020020	Canis familiaris	93.01	0.00e+00	3152.00
IUUC-Cpo-021552	Cavia porcellus	88.88	0.00e+00	3215.00
IUUC-Csa-024216	Chlorocebus sabaeus	97.98	0.00e+00	3505.00
IUUC-Cho-024565	Choloepus hoffmanni	77.38	6.00e-165	575.00
IUUC-Dre-027440	Danio rerio	44.73	0.00e+00	907.00
IUUC-Dno-029583	Dasypus novemcinctus	93.89	0.00e+00	3061.00
IUUC-Dor-030903	Dipodomys ordii	86.72	0.00e+00	2169.00
IUUC-Dme-032023	Drosophila melanogaster	47.56	3.00e-93	338.00
IUUC-Eca-034026	Equus caballus	94.32	0.00e+00	1954.00
IUUC-Eeu-034687	Erinaceus europaeus	92.61	0.00e+00	1143.00
IUUC-Fca-036311	Felis catus	91.83	0.00e+00	3255.00
IUUC-Gmo-039265	Gadus morhua	45.15	0.00e+00	818.00
IUUC-Gac-042202	Gasterosteus aculeatus	47.89	0.00e+00	744.00
IUUC-Ggo-044791	Gorilla gorilla	98.62	0.00e+00	2242.00
IUUC-Hsa-046988	Homo sapiens	99.56	0.00e+00	3373.00
IUUC-Hvu-047762	Hordeum vulgare	36.57	3.00e-20	93.20
IUUC-Itr-048907	Ictidomys tridecemlineatus	91.19	0.00e+00	3367.00
IUUC-Lpe-051476	Leersia perrieri	31.51	3.00e-24	107.00
IUUC-Loc-052252	Lepisosteus oculatus	53.73	0.00e+00	778.00
IUUC-Laf-053703	Loxodonta africana	92.39	0.00e+00	2190.00
IUUC-Mcc-054782	Macaca mulatta	96.96	0.00e+00	2755.00
IUUC-Meu-056046	Macropus eugenii	80.35	0.00e+00	1897.00
IUUC-Mmr-061316	Microcebus murinus	91.53	0.00e+00	2862.00
IUUC-Mdo-062648	Monodelphis domestica	79.41	0.00e+00	2034.00
IUUC-Mmu-063579	Mus musculus	90.39	0.00e+00	3270.00
IUUC-Mac-064935	Musa acuminata	32.64	7.00e-30	125.00
IUUC-Mpu-066710	Mustela putorius furo	92.84	0.00e+00	3231.00
IUUC-Mlu-067559	Myotis lucifugus	90.80	0.00e+00	3221.00
IUUC-Nle-070085	Nomascus leucogenys	96.19	0.00e+00	2291.00
IUUC-Opr-071148	Ochotona princeps	88.51	0.00e+00	3222.00
IUUC-Ont-071626	Oreochromis niloticus	48.54	0.00e+00	785.00
IUUC-Ocu-074475	Oryctolagus cuniculus	90.84	0.00e+00	3149.00
IUUC-Obr-076458	Oryza brachyantha	34.48	4.00e-28	119.00
IUUC-Ogl-077851	Oryza glaberrima	36.26	3.00e-28	120.00
IUUC-Ogu-078706	Oryza glumaepatula	36.26	2.00e-28	121.00
IUUC-Oin-079802	Oryza indica	31.43	3.00e-23	103.00
IUUC-Osa-085421	Oryza sativa	36.26	5.00e-28	119.00
IUUC-Ola-086609	Oryzias latipes	48.52	0.00e+00	753.00
IUUC-Oga-088140	Otolemur garnettii	93.40	0.00e+00	3248.00
IUUC-Oar-089447	Ovis aries	91.84	0.00e+00	2042.00
IUUC-Pan-091930	Papio anubis	98.22	0.00e+00	3511.00
IUUC-Ppa-095221	Physcomitrella patens	36.54	7.00e-31	129.00
IUUC-Pfo-096884	Poecilia formosa	48.68	0.00e+00	781.00
IUUC-Pab-098404	Pongo abelii	86.84	0.00e+00	2518.00
IUUC-Pop-099585	Populus trichocarpa	33.50	1.00e-26	115.00
IUUC-Pca-100949	Procavia capensis	84.98	0.00e+00	1252.00
IUUC-Ppe-101920	Prunus persica	33.01	1.00e-27	118.00
IUUC-Pva-102634	Pteropus vampyrus	91.80	0.00e+00	3291.00
IUUC-Rno-105870	Rattus norvegicus	90.00	0.00e+00	3346.00
IUUC-Sit-110552	Setaria italica	34.33	7.00e-29	122.00
IUUC-Sar-113289	Sorex araneus	89.85	0.00e+00	1763.00
IUUC-Ssc-115509	Sus scrofa	92.70	0.00e+00	3223.00
IUUC-Tru-118413	Takifugu rubripes	52.59	0.00e+00	787.00
IUUC-Tca-121624	Theobroma cacao	32.67	7.00e-28	119.00
IUUC-Tae-125629	Triticum aestivum	36.57	3.00e-20	93.20
IUUC-Tbe-127825	Tupaia belangeri	88.21	0.00e+00	1444.00
IUUC-Ttr-128754	Tursiops truncatus	94.28	0.00e+00	1246.00
IUUC-Xtr-132838	Xenopus tropicalis	49.06	0.00e+00	1011.00
IUUC-Xma-133119	Xiphophorus maculatus	43.09	0.00e+00	976.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence