iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036097

Ensembl Protein ID

ENSFCAP00000001032.3

UniProt Accession

M3VW05; M3VW05_FELCA

Genbank Protein ID

ENSFCAP00000001032

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02135972

Gene Name

VCP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000001112.3	ENSFCAT00000001113.3	ENSFCAP00000001032.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Other/Other	99.86	0.00e+00	1392.00	IUUC-Hsa-046162
UBD/Other/Other	71.72	0.00e+00	1060.00	IUUC-Sce-106244

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Felis catus

Protein Sequence
(Fasta)

MDELQLFRGD TVLLKGKKRR EAVCIVLSDD TCSDEKIRMN RVVRNNLRVH LGDVISIQPC 60
PDVKYGKRIH VLPIDDTVEG ITGNLFEVYL KPYFLEAYRP IRKGDIFLVR GGMRAVEFKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCAAAAGGT GATGACTTAT CAACAGCCAT TCTTAAACAG AAGAACCGTC CCAATCGGTT 60
AATTGTCGAT GAAGCCATTA ATGAGGACAA CAGTGTGGTG TCCTTGTCCC AGGTAAGTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR003593--AAA+_ATPase
IPR005938--AAA_ATPase_CDC48
IPR009010--Asp_de-COase-like_dom
IPR003959--ATPase_AAA_core
IPR003960--ATPase_AAA_CS
IPR004201--Cdc48_dom2
IPR029067--CDC48_domain_2-like
IPR003338--CDC4_N-term_subdom
IPR027417--P-loop_NTPase
IPR015415--Vps4_C

PROSITE

PS00674--AAA

Pfam

PF00004--AAA
PF02933--CDC48_2
PF02359--CDC48_N
PF09336--Vps4_C

SMART

SM00382--AAA
SM01072--CDC48_2
SM01073--CDC48_N

Gene Ontology

GO:0005829--C:cytosol
GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0070062--C:extracellular exosome
GO:0005811--C:lipid particle
GO:0043209--C:myelin sheath
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0000502--C:proteasome complex
GO:0035861--C:site of double-strand break
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:1990730--C:VCP-NSFL1C complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0035800--F:deubiquitinase activator activity
GO:0003723--F:RNA binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070842--P:aggresome assembly
GO:0046034--P:ATP metabolic process
GO:0097352--P:autophagosome maturation
GO:0006302--P:double-strand break repair
GO:0071712--P:ER-associated misfolded protein catabolic process
GO:0072389--P:flavin adenine dinucleotide catabolic process
GO:0006734--P:NADH metabolic process
GO:2001171--P:positive regulation of ATP biosynthetic process
GO:1903007--P:positive regulation of Lys63-specific deubiquitinase activity
GO:0010918--P:positive regulation of mitochondrial membrane potential
GO:1903862--P:positive regulation of oxidative phosphorylation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031334--P:positive regulation of protein complex assembly
GO:0034214--P:protein hexamerization
GO:0018279--P:protein N-linked glycosylation via asparagine
GO:0016567--P:protein ubiquitination
GO:1903715--P:regulation of aerobic respiration
GO:0030970--P:retrograde protein transport, ER to cytosol
GO:0019985--P:translesion synthesis
GO:0030433--P:ubiquitin-dependent ERAD pathway
GO:0019079--P:viral genome replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000524	Aegilops tauschii	81.18	0.00e+00	1149.00
IUUC-Aml-001849	Ailuropoda melanoleuca	100.00	0.00e+00	1397.00
IUUC-Atr-002619	Amborella trichopoda	80.63	0.00e+00	1190.00
IUUC-Apl-004070	Anas platyrhynchos	99.45	0.00e+00	1385.00
IUUC-Aca-004847	Anolis carolinensis	99.45	0.00e+00	1387.00
IUUC-Aly-005406	Arabidopsis lyrata	80.25	0.00e+00	1163.00
IUUC-Ath-006796	Arabidopsis thaliana	80.38	0.00e+00	1180.00
IUUC-Ago-008001	Ashbya gossypii	72.86	0.00e+00	1004.00
IUUC-Acl-008066	Aspergillus clavatus	74.17	0.00e+00	1058.00
IUUC-Afl-008505	Aspergillus flavus	74.11	0.00e+00	1072.00
IUUC-Afu-008840	Aspergillus fumigatus	74.59	0.00e+00	1079.00
IUUC-Ani-009368	Aspergillus nidulans	73.91	0.00e+00	1076.00
IUUC-Ang-009724	Aspergillus niger	74.22	0.00e+00	1073.00
IUUC-Aor-010204	Aspergillus oryzae	74.11	0.00e+00	1072.00
IUUC-Ate-010370	Aspergillus terreus	74.52	0.00e+00	1075.00
IUUC-Ame-011388	Astyanax mexicanus	97.64	0.00e+00	1348.00
IUUC-Bgr-012223	Blumeria graminis	73.80	0.00e+00	1090.00
IUUC-Bta-013188	Bos taurus	100.00	0.00e+00	1396.00
IUUC-Bci-013831	Botrytis cinerea	74.11	0.00e+00	1074.00
IUUC-Bdi-014967	Brachypodium distachyon	81.46	0.00e+00	1191.00
IUUC-Bol-016113	Brassica oleracea	80.25	0.00e+00	1179.00
IUUC-Bra-017796	Brassica rapa	80.25	0.00e+00	1182.00
IUUC-Cel-018243	Caenorhabditis elegans	80.27	0.00e+00	1151.00
IUUC-Cja-019904	Callithrix jacchus	99.04	0.00e+00	1343.00
IUUC-Cfa-020304	Canis familiaris	100.00	0.00e+00	1393.00
IUUC-Cpo-021518	Cavia porcellus	99.86	0.00e+00	1389.00
IUUC-Cre-022719	Chlamydomonas reinhardtii	80.49	0.00e+00	1176.00
IUUC-Csa-023444	Chlorocebus sabaeus	99.86	0.00e+00	1390.00
IUUC-Cho-024482	Choloepus hoffmanni	98.35	0.00e+00	1359.00
IUUC-Cin-025517	Ciona intestinalis	87.16	0.00e+00	1230.00
IUUC-Csv-026060	Ciona savignyi	87.77	0.00e+00	1278.00
IUUC-Cgl-026690	Colletotrichum gloeosporioides	74.73	0.00e+00	1099.00
IUUC-Cne-026910	Cryptococcus neoformans	75.44	0.00e+00	1120.00
IUUC-Cme-027145	Cyanidioschyzon merolae	76.63	0.00e+00	1112.00
IUUC-Dre-028487	Danio rerio	97.91	0.00e+00	1350.00
IUUC-Dno-029257	Dasypus novemcinctus	99.86	0.00e+00	1390.00
IUUC-Dor-030473	Dipodomys ordii	98.08	0.00e+00	1340.00
IUUC-Dse-031319	Dothistroma septosporum	72.40	0.00e+00	1061.00
IUUC-Dme-032203	Drosophila melanogaster	85.30	0.00e+00	1212.00
IUUC-Eca-033311	Equus caballus	99.31	0.00e+00	1380.00
IUUC-Eeu-035293	Erinaceus europaeus	98.87	0.00e+00	687.00
IUUC-Fal-037292	Ficedula albicollis	99.72	0.00e+00	1389.00
IUUC-Fox-037827	Fusarium oxysporum	74.52	0.00e+00	1102.00
IUUC-Fso-038226	Fusarium solani	74.76	0.00e+00	1107.00
IUUC-Gmo-039157	Gadus morhua	90.43	0.00e+00	1235.00
IUUC-Ggr-039951	Gaeumannomyces graminis	74.49	0.00e+00	1080.00
IUUC-Gga-041183	Gallus gallus	99.72	0.00e+00	1389.00
IUUC-Gac-042039	Gasterosteus aculeatus	97.25	0.00e+00	1336.00
IUUC-Gma-044090	Glycine max	80.36	0.00e+00	1197.00
IUUC-Ggo-045568	Gorilla gorilla	99.86	0.00e+00	1390.00
IUUC-Hsa-046162	Homo sapiens	99.86	0.00e+00	1390.00
IUUC-Hvu-047107	Hordeum vulgare	82.43	0.00e+00	951.00
IUUC-Itr-047885	Ictidomys tridecemlineatus	99.59	0.00e+00	1384.00
IUUC-Kpa-049220	Komagataella pastoris	71.49	0.00e+00	1060.00
IUUC-Lch-050657	Latimeria chalumnae	89.55	0.00e+00	1192.00
IUUC-Lpe-051083	Leersia perrieri	81.73	0.00e+00	1181.00
IUUC-Loc-052064	Lepisosteus oculatus	98.19	0.00e+00	1352.00
IUUC-Lma-053323	Leptosphaeria maculans	74.90	0.00e+00	1089.00
IUUC-Laf-054574	Loxodonta africana	99.86	0.00e+00	1390.00
IUUC-Mcc-055448	Macaca mulatta	99.86	0.00e+00	1390.00
IUUC-Meu-056316	Macropus eugenii	92.30	0.00e+00	1259.00
IUUC-Mor-057057	Magnaporthe oryzae	74.35	0.00e+00	1078.00
IUUC-Mpo-057406	Magnaporthe poae	74.76	0.00e+00	1075.00
IUUC-Mtr-057648	Medicago truncatula	80.93	0.00e+00	1197.00
IUUC-Mla-059156	Melampsora laricipopulina	77.88	0.00e+00	1163.00
IUUC-Mga-060004	Meleagris gallopavo	93.30	0.00e+00	1224.00
IUUC-Mvi-060488	Microbotryum violaceum	76.52	0.00e+00	1142.00
IUUC-Mmr-061027	Microcebus murinus	99.86	0.00e+00	1387.00
IUUC-Mdo-062159	Monodelphis domestica	99.86	0.00e+00	1390.00
IUUC-Mmu-063633	Mus musculus	99.86	0.00e+00	1390.00
IUUC-Mac-064919	Musa acuminata	80.53	0.00e+00	1180.00
IUUC-Mpu-066078	Mustela putorius furo	100.00	0.00e+00	1396.00
IUUC-Mlu-067757	Myotis lucifugus	99.72	0.00e+00	1390.00
IUUC-Nfi-068533	Neosartorya fischeri	74.59	0.00e+00	1071.00
IUUC-Ncr-068775	Neurospora crassa	75.17	0.00e+00	1044.00
IUUC-Nle-069424	Nomascus leucogenys	99.86	0.00e+00	1390.00
IUUC-Opr-071147	Ochotona princeps	99.04	0.00e+00	1370.00
IUUC-Ont-071351	Oreochromis niloticus	97.50	0.00e+00	1319.00
IUUC-Oan-073335	Ornithorhynchus anatinus	99.45	0.00e+00	1384.00
IUUC-Ocu-074072	Oryctolagus cuniculus	99.86	0.00e+00	1390.00
IUUC-Oba-075914	Oryza barthii	81.59	0.00e+00	1202.00
IUUC-Obr-076224	Oryza brachyantha	82.01	0.00e+00	1199.00
IUUC-Ogl-077282	Oryza glaberrima	81.59	0.00e+00	1198.00
IUUC-Ogu-078174	Oryza glumaepatula	81.59	0.00e+00	1202.00
IUUC-Oin-079103	Oryza indica	81.59	0.00e+00	1202.00
IUUC-Olo-080675	Oryza longistaminata	81.73	0.00e+00	1203.00
IUUC-Ome-081247	Oryza meridionalis	81.59	0.00e+00	1202.00
IUUC-Oni-082078	Oryza nivara	81.46	0.00e+00	1201.00
IUUC-Opu-083806	Oryza punctata	81.59	0.00e+00	1205.00
IUUC-Oru-084634	Oryza rufipogon	81.59	0.00e+00	1201.00
IUUC-Osa-085960	Oryza sativa	81.59	0.00e+00	1202.00
IUUC-Ola-086382	Oryzias latipes	97.36	0.00e+00	1319.00
IUUC-Olu-087839	Ostreococcus lucimarinus	79.61	0.00e+00	1156.00
IUUC-Oga-088037	Otolemur garnettii	99.59	0.00e+00	1381.00
IUUC-Oar-089684	Ovis aries	100.00	0.00e+00	1397.00
IUUC-Ptr-091378	Pan troglodytes	99.86	0.00e+00	1390.00
IUUC-Pan-092849	Papio anubis	99.86	0.00e+00	1390.00
IUUC-Psi-093725	Pelodiscus sinensis	96.81	0.00e+00	1320.00
IUUC-Pma-094537	Petromyzon marinus	89.43	0.00e+00	692.00
IUUC-Pno-094915	Phaeosphaeria nodorum	78.44	0.00e+00	1036.00
IUUC-Ppa-095632	Physcomitrella patens	80.36	0.00e+00	1144.00
IUUC-Pfo-097440	Poecilia formosa	97.36	0.00e+00	1319.00
IUUC-Pab-098469	Pongo abelii	99.86	0.00e+00	1390.00
IUUC-Pop-100047	Populus trichocarpa	81.18	0.00e+00	1197.00
IUUC-Pca-100399	Procavia capensis	94.91	0.00e+00	1295.00
IUUC-Ppe-101767	Prunus persica	79.81	0.00e+00	1188.00
IUUC-Pva-102426	Pteropus vampyrus	99.04	0.00e+00	1347.00
IUUC-Pgr-103599	Puccinia graminis	77.04	0.00e+00	1141.00
IUUC-Ptt-103740	Puccinia triticina	77.17	0.00e+00	1142.00
IUUC-Pte-104030	Pyrenophora teres	74.79	0.00e+00	1067.00
IUUC-Pyt-104541	Pyrenophora triticirepentis	74.79	0.00e+00	1067.00
IUUC-Rno-105144	Rattus norvegicus	99.86	0.00e+00	1390.00
IUUC-Sce-106244	Saccharomyces cerevisiae	71.31	0.00e+00	1008.00
IUUC-Sha-106589	Sarcophilus harrisii	99.86	0.00e+00	1392.00
IUUC-Sja-107673	Schizosaccharomyces japonicus	72.53	0.00e+00	1050.00
IUUC-Spo-108247	Schizosaccharomyces pombe	73.35	0.00e+00	1029.00
IUUC-Ssl-108642	Sclerotinia sclerotiorum	73.97	0.00e+00	1067.00
IUUC-Smo-108877	Selaginella moellendorffii	80.49	0.00e+00	1182.00
IUUC-Sit-110623	Setaria italica	81.18	0.00e+00	1193.00
IUUC-Sly-111151	Solanum lycopersicum	79.86	0.00e+00	1167.00
IUUC-Stu-111959	Solanum tuberosum	80.41	0.00e+00	1196.00
IUUC-Sar-113021	Sorex araneus	99.86	0.00e+00	1388.00
IUUC-Sbi-114457	Sorghum bicolor	81.87	0.00e+00	1197.00
IUUC-Sre-115052	Sporisorium reilianum	78.55	0.00e+00	1173.00
IUUC-Ssc-116293	Sus scrofa	99.73	0.00e+00	1389.00
IUUC-Tgu-116544	Taeniopygia guttata	96.15	0.00e+00	1304.00
IUUC-Tru-117991	Takifugu rubripes	97.16	0.00e+00	992.00
IUUC-Tsy-119131	Tarsius syrichta	81.16	0.00e+00	1056.00
IUUC-Tni-120192	Tetraodon nigroviridis	95.41	0.00e+00	1307.00
IUUC-Tca-121502	Theobroma cacao	80.63	0.00e+00	1170.00
IUUC-Tre-122189	Trichoderma reesei	74.35	0.00e+00	1083.00
IUUC-Tvi-122310	Trichoderma virens	73.94	0.00e+00	1080.00
IUUC-Tae-124332	Triticum aestivum	81.18	0.00e+00	1168.00
IUUC-Tur-126733	Triticum urartu	80.91	0.00e+00	1152.00
IUUC-Tme-127147	Tuber melanosporum	74.49	0.00e+00	1061.00
IUUC-Tbe-127255	Tupaia belangeri	92.17	0.00e+00	1281.00
IUUC-Ttr-128876	Tursiops truncatus	99.59	0.00e+00	1382.00
IUUC-Uma-129448	Ustilago maydis	78.79	0.00e+00	1164.00
IUUC-Vda-129800	Verticillium dahliae	73.76	0.00e+00	1066.00
IUUC-Vpa-130573	Vicugna pacos	100.00	0.00e+00	764.00
IUUC-Vvi-131622	Vitis vinifera	81.32	0.00e+00	1196.00
IUUC-Xtr-132458	Xenopus tropicalis	99.17	0.00e+00	1382.00
IUUC-Xma-134045	Xiphophorus maculatus	97.36	0.00e+00	1319.00
IUUC-Yli-134382	Yarrowia lipolytica	73.31	0.00e+00	1086.00
IUUC-Zma-134817	Zea mays	81.59	0.00e+00	1199.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence