iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000008672.3	ENSMMUT00000012124.3	ENSMMUP00000011374.2
ENSMMUG00000008672.3	ENSMMUT00000061026.1	ENSMMUP00000061013.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.60e-09	37.5	229	270

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf...kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C++d+   ++ ++ lpC+H+fh  C+  w        ++++CP+Cr
   Q: 229  CPVCKDDYalgER-VRQLPCNHLFHDGCIVPW------LEQHDSCPVCR 270
           ********99777.******************......**********8 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAEASPQPGR YFCHCCSVEI VPRLPDYICP RCESGFIEEL PEETRSTENG SAPSTAPTDQ 60
SRPPLEHVDQ HLFTLPQGYG QFAFGIFDDS FEIPTFPPGA QADEGRDPES RRERDHPSRH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTCGGCCGG CGAGGGAGCA GCAAACGGCC GGCGGCGGGC GCCGCGCGGG GGGCGGGCGG 60
CGCGGAGTAG GCGGCGGCGG CCATGGCCGA GGCGTCGCCG CAGCCCGGAC GGTACTTCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0042127--P:regulation of cell proliferation
GO:0042147--P:retrograde transport, endosome to Golgi
GO:0071629--P:ubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

KEGG

mcc:702842

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000551	Aegilops tauschii	46.73	1.00e-24	107.00
IUUC-Aml-002001	Ailuropoda melanoleuca	94.89	1.00e-147	515.00
IUUC-Atr-002522	Amborella trichopoda	50.53	4.00e-27	114.00
IUUC-Apl-003778	Anas platyrhynchos	77.20	2.00e-95	341.00
IUUC-Aca-005166	Anolis carolinensis	76.10	3.00e-105	374.00
IUUC-Aly-006495	Arabidopsis lyrata	47.62	1.00e-21	96.70
IUUC-Ath-007616	Arabidopsis thaliana	31.09	1.00e-27	117.00
IUUC-Afl-008423	Aspergillus flavus	43.00	6.00e-18	85.50
IUUC-Afu-008920	Aspergillus fumigatus	43.43	5.00e-17	82.40
IUUC-Ani-009396	Aspergillus nidulans	41.84	1.00e-16	80.90
IUUC-Ang-009638	Aspergillus niger	45.19	2.00e-17	83.60
IUUC-Aor-009896	Aspergillus oryzae	43.00	6.00e-18	85.10
IUUC-Ame-010626	Astyanax mexicanus	70.69	3.00e-113	401.00
IUUC-Bgr-012144	Blumeria graminis	35.94	1.00e-18	87.80
IUUC-Bta-012808	Bos taurus	92.44	8.00e-136	476.00
IUUC-Bdi-014137	Brachypodium distachyon	48.62	5.00e-26	111.00
IUUC-Cel-018216	Caenorhabditis elegans	42.11	1.00e-14	73.60
IUUC-Cja-019575	Callithrix jacchus	91.05	1.00e-137	482.00
IUUC-Cfa-020142	Canis familiaris	94.74	3.00e-130	457.00
IUUC-Cpo-022451	Cavia porcellus	92.23	3.00e-138	484.00
IUUC-Csa-023433	Chlorocebus sabaeus	98.71	6.00e-172	596.00
IUUC-Cgl-026759	Colletotrichum gloeosporioides	38.54	9.00e-17	81.60
IUUC-Cne-026837	Cryptococcus neoformans	30.30	2.00e-16	80.50
IUUC-Cme-027122	Cyanidioschyzon merolae	54.00	1.00e-13	71.60
IUUC-Dre-027400	Danio rerio	72.29	7.00e-115	406.00
IUUC-Dno-029349	Dasypus novemcinctus	89.96	4.00e-104	370.00
IUUC-Dor-030103	Dipodomys ordii	94.04	2.00e-120	424.00
IUUC-Eca-034240	Equus caballus	92.00	2.00e-102	364.00
IUUC-Fal-037027	Ficedula albicollis	80.89	2.00e-102	365.00
IUUC-Fox-037736	Fusarium oxysporum	31.75	1.00e-14	74.30
IUUC-Fso-038447	Fusarium solani	37.50	6.00e-16	79.00
IUUC-Gmo-039694	Gadus morhua	69.70	5.00e-119	420.00
IUUC-Ggr-039947	Gaeumannomyces graminis	34.11	5.00e-12	66.20
IUUC-Gga-040682	Gallus gallus	82.41	6.00e-123	433.00
IUUC-Gac-041369	Gasterosteus aculeatus	67.21	1.00e-110	392.00
IUUC-Gma-043297	Glycine max	32.14	1.00e-28	120.00
IUUC-Ggo-045421	Gorilla gorilla	97.01	3.00e-142	497.00
IUUC-Hsa-046723	Homo sapiens	99.31	2.00e-159	554.00
IUUC-Itr-048435	Ictidomys tridecemlineatus	94.01	1.00e-125	442.00
IUUC-Lch-050071	Latimeria chalumnae	79.55	7.00e-123	433.00
IUUC-Lpe-051427	Leersia perrieri	49.54	1.00e-26	113.00
IUUC-Loc-052470	Lepisosteus oculatus	64.31	1.00e-92	332.00
IUUC-Lma-053066	Leptosphaeria maculans	44.00	6.00e-21	95.90
IUUC-Laf-054249	Loxodonta africana	70.82	2.00e-69	254.00
IUUC-Meu-056622	Macropus eugenii	64.65	3.00e-49	188.00
IUUC-Mor-057098	Magnaporthe oryzae	36.11	2.00e-12	67.40
IUUC-Mpo-057470	Magnaporthe poae	33.06	5.00e-12	66.20
IUUC-Mtr-057711	Medicago truncatula	41.98	4.00e-24	104.00
IUUC-Mga-059349	Meleagris gallopavo	78.28	8.00e-110	390.00
IUUC-Mvi-060434	Microbotryum violaceum	37.69	1.00e-19	90.90
IUUC-Mmr-060653	Microcebus murinus	94.25	7.00e-154	536.00
IUUC-Mdo-062442	Monodelphis domestica	87.59	8.00e-143	499.00
IUUC-Mmu-064148	Mus musculus	93.45	8.00e-143	499.00
IUUC-Mpu-065917	Mustela putorius furo	91.72	8.00e-133	466.00
IUUC-Mlu-067495	Myotis lucifugus	93.79	1.00e-143	502.00
IUUC-Nfi-068352	Neosartorya fischeri	43.43	3.00e-17	82.80
IUUC-Ncr-068908	Neurospora crassa	31.39	2.00e-18	87.00
IUUC-Nle-069274	Nomascus leucogenys	98.61	8.00e-149	519.00
IUUC-Opr-070359	Ochotona princeps	84.45	1.00e-89	322.00
IUUC-Ont-071505	Oreochromis niloticus	72.47	3.00e-116	411.00
IUUC-Oan-073225	Ornithorhynchus anatinus	80.00	4.00e-112	397.00
IUUC-Oba-075047	Oryza barthii	50.00	5.00e-27	114.00
IUUC-Obr-076829	Oryza brachyantha	51.82	8.00e-28	117.00
IUUC-Ogl-077378	Oryza glaberrima	50.00	5.00e-27	114.00
IUUC-Ogu-078709	Oryza glumaepatula	50.00	5.00e-27	114.00
IUUC-Oin-079400	Oryza indica	49.45	4.00e-23	101.00
IUUC-Olo-080762	Oryza longistaminata	50.00	5.00e-27	114.00
IUUC-Ome-081151	Oryza meridionalis	49.49	5.00e-23	101.00
IUUC-Oni-083090	Oryza nivara	50.00	5.00e-27	114.00
IUUC-Opu-083898	Oryza punctata	51.92	9.00e-27	114.00
IUUC-Oru-084267	Oryza rufipogon	50.00	4.00e-27	115.00
IUUC-Osa-086229	Oryza sativa	50.00	5.00e-27	114.00
IUUC-Ola-086315	Oryzias latipes	66.45	4.00e-110	390.00
IUUC-Oga-088067	Otolemur garnettii	94.14	2.00e-139	488.00
IUUC-Ptr-091404	Pan troglodytes	99.10	2.00e-118	418.00
IUUC-Pan-092424	Papio anubis	96.75	1.00e-160	558.00
IUUC-Psi-093171	Pelodiscus sinensis	83.15	6.00e-113	400.00
IUUC-Pma-094408	Petromyzon marinus	45.74	2.00e-63	235.00
IUUC-Ppa-095942	Physcomitrella patens	45.54	1.00e-24	107.00
IUUC-Pfo-097402	Poecilia formosa	69.76	2.00e-113	401.00
IUUC-Pab-097834	Pongo abelii	96.88	9.00e-115	405.00
IUUC-Pop-099462	Populus trichocarpa	50.51	2.00e-25	109.00
IUUC-Pca-100442	Procavia capensis	93.25	1.00e-99	355.00
IUUC-Ppe-101324	Prunus persica	49.54	1.00e-25	110.00
IUUC-Pva-103240	Pteropus vampyrus	94.16	7.00e-155	539.00
IUUC-Pgr-103273	Puccinia graminis	34.42	8.00e-18	84.30
IUUC-Ptt-103768	Puccinia triticina	39.81	7.00e-16	79.00
IUUC-Pte-104223	Pyrenophora teres	40.94	9.00e-22	98.60
IUUC-Pyt-104653	Pyrenophora triticirepentis	40.94	1.00e-21	97.80
IUUC-Rno-105203	Rattus norvegicus	93.79	2.00e-143	501.00
IUUC-Sha-107638	Sarcophilus harrisii	84.98	3.00e-127	447.00
IUUC-Ssl-108600	Sclerotinia sclerotiorum	30.43	1.00e-12	68.60
IUUC-Smo-109651	Selaginella moellendorffii	52.81	9.00e-24	101.00
IUUC-Sit-110648	Setaria italica	51.35	3.00e-28	119.00
IUUC-Sly-111407	Solanum lycopersicum	31.32	4.00e-26	111.00
IUUC-Stu-112467	Solanum tuberosum	30.96	2.00e-26	112.00
IUUC-Sbi-114297	Sorghum bicolor	49.55	3.00e-27	115.00
IUUC-Tgu-117502	Taeniopygia guttata	82.07	6.00e-119	420.00
IUUC-Tru-117681	Takifugu rubripes	68.73	6.00e-112	397.00
IUUC-Tni-120092	Tetraodon nigroviridis	65.51	8.00e-107	379.00
IUUC-Tca-121480	Theobroma cacao	48.08	7.00e-26	110.00
IUUC-Tre-122013	Trichoderma reesei	33.55	2.00e-16	80.90
IUUC-Tvi-122598	Trichoderma virens	32.69	9.00e-17	81.60
IUUC-Tae-124679	Triticum aestivum	46.73	1.00e-24	107.00
IUUC-Tur-126792	Triticum urartu	54.26	1.00e-21	96.70
IUUC-Ttr-128843	Tursiops truncatus	93.45	8.00e-143	499.00
IUUC-Vda-129671	Verticillium dahliae	33.33	2.00e-15	77.40
IUUC-Vvi-131335	Vitis vinifera	31.58	6.00e-26	111.00
IUUC-Xtr-132815	Xenopus tropicalis	56.06	2.00e-91	328.00
IUUC-Xma-133481	Xiphophorus maculatus	69.42	4.00e-113	400.00
IUUC-Zma-135326	Zea mays	50.00	1.00e-25	109.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence