iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-055325

Ensembl Protein ID

ENSMMUP00000050952.1

UniProt Accession

H9FR49; H9FR49_MACMU

Genbank Protein ID

AFE77108.1; AFH31452.1

Protein Name

Epidermal growth factor receptor substrate 15 isoform A

Genbank Nucleotide ID

JSUE03001376; JU474648

Gene Name

EPS15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000012055.3	ENSMMUT00000053926.1	ENSMMUP00000050952.1
ENSMMUG00000012055.3	ENSMMUT00000016881.3	ENSMMUP00000015810.3
ENSMMUG00000012055.3	ENSMMUT00000016884.3	ENSMMUP00000015813.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/DUIM	98.19	0.00e+00	1579.00	IUUC-Hsa-046286
UBD/Alpha-Helix/UIM	89.16	0.00e+00	1385.00	IUUC-Mmu-064091
UBD/Alpha-Helix/UBA	28.61	1.00e-34	143.00	IUUC-Sce-106303

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAAAAQLSLT QLSSGNPVYE KYYRQVDTGN TGRVFASDAA AFLKKSGLPD LILGKIWDLA 60
DTDGKGILNK QEFFVALRLV ACAQNGLEVS LSSLNLAVPP PRFHDTSSPL LISGTSAAEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATAAAGTGC CATTATTATT TTCTATCATT ATCTCATTTA GTCCTTGTAA CCAACTTGGC 60
CTCTGGTTAT AATTTCCCCC ATTTTTCAGA AGCAGGAGCT CAGCGTAGGT AGGTGGCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0675--Receptor
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR003903--UIM_dom

PROSITE

PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50330--UIM

Pfam

PF12763--EF-hand_4

SMART

SM00054--EFh
SM00027--EH
SM00726--UIM

Gene Ontology

GO:0016235--C:aggresome
GO:0030122--C:AP-2 adaptor complex
GO:0060170--C:ciliary membrane
GO:0005829--C:cytosol
GO:0043231--C:intracellular membrane-bounded organelle
GO:0005509--F:calcium ion binding
GO:0048268--P:clathrin coat assembly
GO:0006895--P:Golgi to endosome transport
GO:0019065--P:receptor-mediated endocytosis of virus by host cell

KEGG

mcc:714767

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001596	Ailuropoda melanoleuca	92.40	0.00e+00	1417.00
IUUC-Apl-003288	Anas platyrhynchos	75.17	0.00e+00	1096.00
IUUC-Aca-005333	Anolis carolinensis	70.42	0.00e+00	1097.00
IUUC-Ago-007867	Ashbya gossypii	27.38	6.00e-31	130.00
IUUC-Bta-013028	Bos taurus	91.30	0.00e+00	1459.00
IUUC-Bol-015187	Brassica oleracea	36.96	1.00e-12	68.60
IUUC-Bra-017706	Brassica rapa	36.25	2.00e-12	68.60
IUUC-Cja-019821	Callithrix jacchus	94.99	0.00e+00	1575.00
IUUC-Cfa-021233	Canis familiaris	92.27	0.00e+00	1139.00
IUUC-Cpo-022339	Cavia porcellus	90.33	0.00e+00	1474.00
IUUC-Csa-024072	Chlorocebus sabaeus	99.55	0.00e+00	1561.00
IUUC-Cho-025000	Choloepus hoffmanni	74.77	0.00e+00	1132.00
IUUC-Dre-027504	Danio rerio	61.36	1.00e-171	597.00
IUUC-Dno-029498	Dasypus novemcinctus	87.19	0.00e+00	1402.00
IUUC-Dor-030630	Dipodomys ordii	88.53	0.00e+00	1405.00
IUUC-Ete-032737	Echinops telfairi	75.58	0.00e+00	1103.00
IUUC-Eca-033328	Equus caballus	93.25	0.00e+00	1463.00
IUUC-Eeu-035267	Erinaceus europaeus	82.63	0.00e+00	926.00
IUUC-Fca-035511	Felis catus	93.46	0.00e+00	1491.00
IUUC-Fal-036796	Ficedula albicollis	73.41	0.00e+00	1091.00
IUUC-Gga-040315	Gallus gallus	73.34	0.00e+00	1120.00
IUUC-Gac-042011	Gasterosteus aculeatus	52.89	0.00e+00	701.00
IUUC-Ggo-045493	Gorilla gorilla	91.94	0.00e+00	1469.00
IUUC-Hsa-046286	Homo sapiens	98.19	0.00e+00	1600.00
IUUC-Loc-052749	Lepisosteus oculatus	52.42	2.00e-161	563.00
IUUC-Laf-054158	Loxodonta africana	90.25	0.00e+00	1441.00
IUUC-Mtr-058311	Medicago truncatula	33.33	9.00e-14	72.80
IUUC-Mga-060058	Meleagris gallopavo	72.38	0.00e+00	1146.00
IUUC-Mmr-061060	Microcebus murinus	94.47	0.00e+00	1503.00
IUUC-Mmu-064091	Mus musculus	89.16	0.00e+00	1276.00
IUUC-Mpu-065932	Mustela putorius furo	92.45	0.00e+00	1457.00
IUUC-Mlu-067488	Myotis lucifugus	90.48	0.00e+00	1451.00
IUUC-Nle-068996	Nomascus leucogenys	98.41	0.00e+00	1576.00
IUUC-Opr-070750	Ochotona princeps	83.14	7.00e-138	484.00
IUUC-Ont-071424	Oreochromis niloticus	55.46	0.00e+00	658.00
IUUC-Oan-073457	Ornithorhynchus anatinus	66.76	0.00e+00	743.00
IUUC-Ocu-074535	Oryctolagus cuniculus	93.69	0.00e+00	1477.00
IUUC-Oba-075548	Oryza barthii	35.64	3.00e-13	71.20
IUUC-Ogl-077317	Oryza glaberrima	35.64	3.00e-13	71.20
IUUC-Ogu-078266	Oryza glumaepatula	35.64	3.00e-13	71.20
IUUC-Oin-079539	Oryza indica	35.64	3.00e-13	71.20
IUUC-Ome-081550	Oryza meridionalis	35.64	3.00e-13	71.20
IUUC-Oni-082418	Oryza nivara	35.64	3.00e-13	71.20
IUUC-Opu-084149	Oryza punctata	39.73	7.00e-13	70.10
IUUC-Oru-084223	Oryza rufipogon	35.64	3.00e-13	71.20
IUUC-Osa-085387	Oryza sativa	35.64	3.00e-13	71.20
IUUC-Ola-087107	Oryzias latipes	49.84	0.00e+00	639.00
IUUC-Oga-088532	Otolemur garnettii	90.22	0.00e+00	1448.00
IUUC-Oar-089833	Ovis aries	91.29	0.00e+00	1482.00
IUUC-Ptr-090733	Pan troglodytes	98.19	0.00e+00	1580.00
IUUC-Pan-092491	Papio anubis	95.13	0.00e+00	1471.00
IUUC-Psi-094063	Pelodiscus sinensis	75.36	0.00e+00	1148.00
IUUC-Pma-094451	Petromyzon marinus	55.16	5.00e-100	357.00
IUUC-Ppa-095176	Physcomitrella patens	35.79	3.00e-14	74.70
IUUC-Pab-098749	Pongo abelii	98.33	0.00e+00	1602.00
IUUC-Pop-099501	Populus trichocarpa	32.74	9.00e-13	69.30
IUUC-Pca-100378	Procavia capensis	77.00	0.00e+00	894.00
IUUC-Pva-102739	Pteropus vampyrus	92.89	0.00e+00	1320.00
IUUC-Rno-105042	Rattus norvegicus	87.80	0.00e+00	1360.00
IUUC-Sce-106303	Saccharomyces cerevisiae	28.32	1.00e-34	142.00
IUUC-Spo-108370	Schizosaccharomyces pombe	27.33	3.00e-33	137.00
IUUC-Smo-109013	Selaginella moellendorffii	41.30	2.00e-16	77.00
IUUC-Sit-110002	Setaria italica	23.19	9.00e-14	73.20
IUUC-Sly-111403	Solanum lycopersicum	32.52	3.00e-12	68.20
IUUC-Stu-112258	Solanum tuberosum	35.80	8.00e-10	58.50
IUUC-Sar-113358	Sorex araneus	74.67	0.00e+00	963.00
IUUC-Ssc-115746	Sus scrofa	90.97	0.00e+00	1441.00
IUUC-Tgu-117351	Taeniopygia guttata	73.30	0.00e+00	1091.00
IUUC-Tru-117870	Takifugu rubripes	56.88	0.00e+00	732.00
IUUC-Tsy-118873	Tarsius syrichta	84.42	0.00e+00	943.00
IUUC-Tni-120351	Tetraodon nigroviridis	57.07	0.00e+00	726.00
IUUC-Tca-121631	Theobroma cacao	45.45	2.00e-12	68.20
IUUC-Tbe-127307	Tupaia belangeri	90.66	0.00e+00	1390.00
IUUC-Ttr-128775	Tursiops truncatus	89.34	0.00e+00	1352.00
IUUC-Vpa-130684	Vicugna pacos	86.42	0.00e+00	1382.00
IUUC-Xtr-132716	Xenopus tropicalis	58.21	0.00e+00	902.00
IUUC-Xma-133907	Xiphophorus maculatus	53.04	0.00e+00	664.00
IUUC-Yli-134577	Yarrowia lipolytica	28.41	5.00e-37	150.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence