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Tag Content
UUCD2 ID IUUC-Dre-028515
UUCD1 version UUC-DaR-00686
Ensembl Protein ID ENSDARP00000122687.1
UniProt Accession F1QDT3; F1QDT3_DANRE
Genbank Protein ID ENSDARP00000074155
Protein Name Notchless homolog 1 (Drosophila)
Genbank Nucleotide ID CR926463
Gene Name nle1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000057105.5 ENSDART00000148333.2 ENSDARP00000122687.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.70e-62 204.8 403 439
UBD/Beta-Prp 7.40e-76 256.1 97 289
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH ++v+ +a+  d +llvsGs D t+kvWD++tg+l
   Q: 403  GHVGPVYQVAWsADsRLLVSGSSDSTLKVWDIKTGKL 439
           8***********555*****************99975 PP
   

   UBD/Beta-Prp
   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleet 132
           + +sl+gh+++v +v fsp+gk+l++gs D t++ wdlst ++ ht +gh++ vls+++sp+g+kl+sG + + i +wd  tg+ + +t
   Q: 97   CTSSLEGHTEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHHTSRGHTHWVLSIAWSPDGKKLASGCKNSQIFLWDPVTGKQIGKT 185
           4789************************************************************************************* PP
   S: 133  lsghdgvvncvvv.....hpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvr 216
           l+gh+++++ +++     +p++++l+s s+D t+r+Wd   g   + ltg ht+sv+++++  +g  l + s+d+t+k+w  + g   r
   Q: 186  LTGHTKWITWLCWeplhlNPECRYLASTSKDCTIRIWDTVLGHYDKILTG-HTHSVTCVKWGGDG-LLYTSSQDRTIKVWRAKDGVQCR 272
           ********987652222267899**************************9.************98.9********************** PP
   S: 217  tlnghtdnvksvrfspnde 235
           tl+gh  +v+ +++s  ++
   Q: 273  TLQGHAHWVNTLALS--TD 289
           ************999..33 PP
   
Organism Danio rerio
Protein Sequence
(Fasta)
MSADVERVLI QLQDEAGEVL GSPFDVPLDI SPDKLQLVCN ALLQKEEPVP FLFFVKDAEL 60
VSSLGSCIQT LGLETEQVLP VVYQPQAVFR VRAVARCTSS LEGHTEAVIS VAFSPTGKYL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-028515|E3,WD_repeat;UBD,Beta-Prp|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TGCGTCCGAA ATACTGCACA CTGTACGCGT GGAGTGAGTG TGCGGTGATC AATATCGACA 60
GGTATTTACC ATGTTGACAG TATTGAGTTT TGTAAATGTA TTGAGTTCTT GCTGTTTACT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-028515|E3,WD_repeat;UBD,Beta-Prp|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR012972--NLE
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08154--NLE
PF00400--WD40
PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005730--C:nucleolus
GO:0005840--C:ribosome
GO:0007219--P:Notch signaling pathway
GO:0000027--P:ribosomal large subunit assembly
KEGG dre:553606
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000437 Aegilops tauschii 58.37 2.00e-162 565.00
IUUC-Aml-001793 Ailuropoda melanoleuca 76.96 0.00e+00 796.00
IUUC-Atr-002507 Amborella trichopoda 59.49 8.00e-164 570.00
IUUC-Apl-003964 Anas platyrhynchos 81.06 0.00e+00 781.00
IUUC-Aly-006396 Arabidopsis lyrata 55.86 3.00e-158 551.00
IUUC-Ath-007278 Arabidopsis thaliana 56.84 3.00e-158 551.00
IUUC-Ago-007951 Ashbya gossypii 48.15 3.00e-125 442.00
IUUC-Acl-008298 Aspergillus clavatus 50.00 3.00e-125 442.00
IUUC-Afl-008581 Aspergillus flavus 55.28 8.00e-112 396.00
IUUC-Afu-008906 Aspergillus fumigatus 48.97 4.00e-122 431.00
IUUC-Ani-009189 Aspergillus nidulans 46.17 1.00e-120 426.00
IUUC-Ang-009630 Aspergillus niger 49.67 4.00e-127 448.00
IUUC-Aor-010038 Aspergillus oryzae 50.21 6.00e-131 461.00
IUUC-Ate-010278 Aspergillus terreus 48.11 1.00e-125 443.00
IUUC-Ame-011890 Astyanax mexicanus 91.60 0.00e+00 910.00
IUUC-Bgr-012011 Blumeria graminis 49.69 8.00e-132 463.00
IUUC-Bta-012964 Bos taurus 77.59 0.00e+00 799.00
IUUC-Bci-013592 Botrytis cinerea 51.60 9.00e-121 427.00
IUUC-Bdi-015035 Brachypodium distachyon 59.31 8.00e-165 573.00
IUUC-Bol-015501 Brassica oleracea 57.48 3.00e-158 551.00
IUUC-Bra-017642 Brassica rapa 57.48 2.00e-158 551.00
IUUC-Cel-018430 Caenorhabditis elegans 59.19 3.00e-164 571.00
IUUC-Cja-019125 Callithrix jacchus 78.44 0.00e+00 806.00
IUUC-Cfa-021013 Canis familiaris 77.37 0.00e+00 728.00
IUUC-Cpo-021743 Cavia porcellus 76.74 0.00e+00 796.00
IUUC-Cre-022973 Chlamydomonas reinhardtii 44.59 9.00e-114 403.00
IUUC-Csa-024270 Chlorocebus sabaeus 77.31 0.00e+00 799.00
IUUC-Cin-025795 Ciona intestinalis 65.88 0.00e+00 665.00
IUUC-Csv-025953 Ciona savignyi 66.10 0.00e+00 669.00
IUUC-Cgl-026517 Colletotrichum gloeosporioides 50.36 2.00e-107 382.00
IUUC-Cne-026901 Cryptococcus neoformans 47.02 4.00e-129 454.00
IUUC-Cme-027281 Cyanidioschyzon merolae 45.05 1.00e-107 383.00
IUUC-Dno-029596 Dasypus novemcinctus 77.64 0.00e+00 796.00
IUUC-Dor-030494 Dipodomys ordii 77.28 0.00e+00 790.00
IUUC-Dse-031538 Dothistroma septosporum 51.03 1.00e-135 476.00
IUUC-Dme-031974 Drosophila melanogaster 58.03 3.00e-162 564.00
IUUC-Ete-032948 Echinops telfairi 82.78 2.00e-104 372.00
IUUC-Eca-033399 Equus caballus 78.13 0.00e+00 798.00
IUUC-Eeu-035013 Erinaceus europaeus 83.25 1.00e-104 373.00
IUUC-Fca-035860 Felis catus 78.22 0.00e+00 802.00
IUUC-Fal-037069 Ficedula albicollis 82.87 8.00e-126 442.00
IUUC-Fox-038059 Fusarium oxysporum 47.08 8.00e-123 434.00
IUUC-Fso-038445 Fusarium solani 48.33 2.00e-124 439.00
IUUC-Gmo-039319 Gadus morhua 83.90 0.00e+00 797.00
IUUC-Ggr-040095 Gaeumannomyces graminis 48.65 8.00e-125 440.00
IUUC-Gga-040303 Gallus gallus 82.47 6.00e-126 443.00
IUUC-Gac-042267 Gasterosteus aculeatus 85.71 0.00e+00 812.00
IUUC-Gma-044360 Glycine max 58.30 5.00e-164 570.00
IUUC-Ggo-044637 Gorilla gorilla 77.71 0.00e+00 795.00
IUUC-Hsa-046128 Homo sapiens 77.52 0.00e+00 805.00
IUUC-Hvu-047373 Hordeum vulgare 58.24 8.00e-162 563.00
IUUC-Itr-048070 Ictidomys tridecemlineatus 76.78 0.00e+00 795.00
IUUC-Kpa-049274 Komagataella pastoris 46.63 2.00e-127 449.00
IUUC-Lch-049907 Latimeria chalumnae 78.71 0.00e+00 797.00
IUUC-Lpe-050778 Leersia perrieri 53.16 1.00e-144 506.00
IUUC-Loc-051889 Lepisosteus oculatus 84.87 0.00e+00 857.00
IUUC-Lma-053041 Leptosphaeria maculans 50.12 8.00e-121 427.00
IUUC-Laf-053598 Loxodonta africana 78.22 0.00e+00 801.00
IUUC-Mcc-055660 Macaca mulatta 77.52 0.00e+00 800.00
IUUC-Meu-056197 Macropus eugenii 68.64 0.00e+00 689.00
IUUC-Mor-056949 Magnaporthe oryzae 47.20 2.00e-121 429.00
IUUC-Mpo-057571 Magnaporthe poae 54.17 3.00e-64 239.00
IUUC-Mtr-058530 Medicago truncatula 60.00 5.00e-163 567.00
IUUC-Mla-059133 Melampsora laricipopulina 46.87 7.00e-124 437.00
IUUC-Mga-059252 Meleagris gallopavo 83.01 0.00e+00 648.00
IUUC-Mvi-060522 Microbotryum violaceum 47.36 4.00e-129 454.00
IUUC-Mmr-061117 Microcebus murinus 77.00 0.00e+00 792.00
IUUC-Mdo-062892 Monodelphis domestica 78.15 0.00e+00 800.00
IUUC-Mmu-064108 Mus musculus 77.64 0.00e+00 781.00
IUUC-Mac-064430 Musa acuminata 60.17 7.00e-168 583.00
IUUC-Mpu-065882 Mustela putorius furo 77.00 0.00e+00 794.00
IUUC-Mlu-068123 Myotis lucifugus 78.01 0.00e+00 803.00
IUUC-Nfi-068484 Neosartorya fischeri 49.48 7.00e-124 437.00
IUUC-Ncr-068649 Neurospora crassa 45.24 7.00e-114 404.00
IUUC-Nle-069140 Nomascus leucogenys 78.13 0.00e+00 801.00
IUUC-Opr-070220 Ochotona princeps 72.34 0.00e+00 696.00
IUUC-Ont-072643 Oreochromis niloticus 88.03 0.00e+00 878.00
IUUC-Ocu-074007 Oryctolagus cuniculus 77.80 0.00e+00 780.00
IUUC-Oba-075904 Oryza barthii 58.67 2.00e-164 572.00
IUUC-Obr-076280 Oryza brachyantha 58.46 6.00e-164 570.00
IUUC-Ogl-077425 Oryza glaberrima 58.89 9.00e-165 573.00
IUUC-Ogu-078586 Oryza glumaepatula 58.67 2.00e-164 572.00
IUUC-Oin-079489 Oryza indica 56.75 9.00e-156 543.00
IUUC-Olo-080766 Oryza longistaminata 58.33 9.00e-164 570.00
IUUC-Ome-081905 Oryza meridionalis 58.89 2.00e-164 572.00
IUUC-Oni-083022 Oryza nivara 58.67 1.00e-164 572.00
IUUC-Opu-083615 Oryza punctata 58.89 1.00e-164 572.00
IUUC-Oru-085076 Oryza rufipogon 58.67 2.00e-164 572.00
IUUC-Osa-085744 Oryza sativa 59.10 1.00e-165 575.00
IUUC-Ola-087290 Oryzias latipes 87.39 0.00e+00 872.00
IUUC-Olu-087898 Ostreococcus lucimarinus 51.88 4.00e-140 491.00
IUUC-Oga-088980 Otolemur garnettii 76.65 0.00e+00 793.00
IUUC-Oar-089580 Ovis aries 76.53 0.00e+00 686.00
IUUC-Ptr-090845 Pan troglodytes 77.92 0.00e+00 800.00
IUUC-Pan-092836 Papio anubis 77.52 0.00e+00 802.00
IUUC-Psi-093965 Pelodiscus sinensis 75.21 8.00e-51 191.00
IUUC-Pno-095052 Phaeosphaeria nodorum 49.48 4.00e-128 451.00
IUUC-Ppa-095432 Physcomitrella patens 59.28 4.00e-169 587.00
IUUC-Pfo-096963 Poecilia formosa 80.46 0.00e+00 767.00
IUUC-Pab-097716 Pongo abelii 74.31 0.00e+00 758.00
IUUC-Pop-099224 Populus trichocarpa 58.72 6.00e-165 573.00
IUUC-Pca-100682 Procavia capensis 77.46 2.00e-168 584.00
IUUC-Ppe-101819 Prunus persica 57.74 3.00e-162 565.00
IUUC-Pva-102338 Pteropus vampyrus 75.63 2.00e-170 591.00
IUUC-Pgr-103583 Puccinia graminis 55.42 3.00e-130 459.00
IUUC-Ptt-103737 Puccinia triticina 45.39 2.00e-96 346.00
IUUC-Pte-104150 Pyrenophora teres 51.92 2.00e-126 446.00
IUUC-Pyt-104606 Pyrenophora triticirepentis 51.69 3.00e-126 445.00
IUUC-Rno-105987 Rattus norvegicus 77.54 0.00e+00 798.00
IUUC-Sce-106315 Saccharomyces cerevisiae 48.58 4.00e-128 451.00
IUUC-Sha-107273 Sarcophilus harrisii 76.89 0.00e+00 801.00
IUUC-Sja-107677 Schizosaccharomyces japonicus 49.06 5.00e-121 428.00
IUUC-Spo-108092 Schizosaccharomyces pombe 51.26 4.00e-125 441.00
IUUC-Ssl-108442 Sclerotinia sclerotiorum 46.28 2.00e-118 419.00
IUUC-Smo-108855 Selaginella moellendorffii 55.60 9.00e-163 566.00
IUUC-Sit-110329 Setaria italica 58.67 7.00e-164 570.00
IUUC-Sly-111830 Solanum lycopersicum 60.39 2.00e-167 582.00
IUUC-Stu-112603 Solanum tuberosum 60.17 1.00e-166 579.00
IUUC-Sar-113504 Sorex araneus 71.63 3.00e-58 219.00
IUUC-Sbi-114560 Sorghum bicolor 58.24 5.00e-162 564.00
IUUC-Sre-115133 Sporisorium reilianum 40.34 5.00e-119 421.00
IUUC-Ssc-115903 Sus scrofa 78.22 0.00e+00 802.00
IUUC-Tgu-116798 Taeniopygia guttata 81.61 0.00e+00 819.00
IUUC-Tru-118361 Takifugu rubripes 85.95 0.00e+00 856.00
IUUC-Tsy-118849 Tarsius syrichta 77.61 0.00e+00 795.00
IUUC-Tni-120094 Tetraodon nigroviridis 85.53 0.00e+00 855.00
IUUC-Tca-121634 Theobroma cacao 58.30 2.00e-161 561.00
IUUC-Tre-122051 Trichoderma reesei 47.82 2.00e-119 422.00
IUUC-Tvi-122322 Trichoderma virens 48.65 2.00e-122 432.00
IUUC-Tae-125822 Triticum aestivum 58.46 1.00e-162 566.00
IUUC-Tur-126766 Triticum urartu 52.00 5.00e-154 538.00
IUUC-Tme-127175 Tuber melanosporum 51.34 3.00e-133 468.00
IUUC-Tbe-127779 Tupaia belangeri 77.52 0.00e+00 706.00
IUUC-Ttr-128224 Tursiops truncatus 75.23 0.00e+00 691.00
IUUC-Uma-129537 Ustilago maydis 45.21 2.00e-121 429.00
IUUC-Vda-129927 Verticillium dahliae 47.07 6.00e-114 404.00
IUUC-Vpa-130658 Vicugna pacos 67.66 0.00e+00 667.00
IUUC-Vvi-131659 Vitis vinifera 59.49 7.00e-167 580.00
IUUC-Xtr-132918 Xenopus tropicalis 77.15 0.00e+00 781.00
IUUC-Xma-133700 Xiphophorus maculatus 89.50 0.00e+00 884.00
IUUC-Yli-134478 Yarrowia lipolytica 49.18 2.00e-134 472.00
IUUC-Zma-135835 Zea mays 55.78 1.00e-158 552.00
Created Date 25-Jun-2017

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