iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003380

Ensembl Protein ID

ENSAPLP00000002469.1

UniProt Accession

U3I5E8; U3I5E8_ANAPL

Genbank Protein ID

ENSAPLP00000002469

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01034981

Gene Name

USP46

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000003005.1	ENSAPLT00000003058.1	ENSAPLP00000002469.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.70e-99	331.2	37	366

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re++l+ +k +      +++k++ll++l++lf+++   k+k +++ p+++++ l+ke+  f++y
   Q: 37   FGLVNFGNTCYCNSVLQALYFCRPFRENVLS-YKAQ------QKKKENLLTCLADLFHSIAtqKKKVGVIPPKKFISRLRKENDLFDNY 118
           6******************************.3333......567899************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDa+Efl++ll+++ + l   ++++k+e+++ + ++ ++++ e+++k++ ++++++Fqg+l+++++cl+c++vss++e+fldls++v
   Q: 119  MQQDAHEFLNYLLNTIADIL---QEEKKQEKQNGKLKNGNMNEAEENNKQELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDV 204
           ********************...33444445455555566666778888888************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           ++++     s+++cL++f+++e+l++e+kyyce+c++kqea+k++++kklP +L lhLkRf++ e+ ++ +k++ +v fpleL l  f+
   Q: 205  EQNT-----SITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRL--FN 286
           ****.....9**********************************************************************55555..77 PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
           ts  ++++ ++ Y+L+avvvH G +++ GHY+++vk+ +g WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 287  TSG-DAVNLDRMYDLVAVVVHCGsGPNRGHYITIVKS-HGFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 366
           774.45556****************************.888*******************999*****************97 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

SCLAISKTGS AWLIGTNASA LEKDIGPEQF PINEHYFGLV NFGNTCYCNS VLQALYFCRP 60
FRENVLSYKA QQKKKENLLT CLADLFHSIA TQKKKVGVIP PKKFISRLRK ENDLFDNYMQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGTGCTTGG CCATTAGTAA GACAGGGTCA GCTTGGCTAA TCGTAAGTGA AAGGAAAACA 60
TGCATTTCTT GATGCTGTCC ATGACTTTAC TTTAGAGTCT TAATGTTCTA CATTAATTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008343--P:adult feeding behavior
GO:0001662--P:behavioral fear response
GO:0048149--P:behavioral response to ethanol
GO:0016579--P:protein deubiquitination
GO:0032228--P:regulation of synaptic transmission, GABAergic
GO:0060013--P:righting reflex
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000193	Aegilops tauschii	58.90	1.00e-123	436.00
IUUC-Aml-002353	Ailuropoda melanoleuca	97.49	0.00e+00	689.00
IUUC-Atr-002650	Amborella trichopoda	59.29	1.00e-124	439.00
IUUC-Aca-005031	Anolis carolinensis	94.81	0.00e+00	733.00
IUUC-Aly-005830	Arabidopsis lyrata	58.54	1.00e-121	428.00
IUUC-Ath-006663	Arabidopsis thaliana	59.07	6.00e-125	440.00
IUUC-Ame-010862	Astyanax mexicanus	91.87	0.00e+00	704.00
IUUC-Bta-013023	Bos taurus	98.59	0.00e+00	689.00
IUUC-Bdi-014008	Brachypodium distachyon	60.27	4.00e-125	440.00
IUUC-Bol-015409	Brassica oleracea	58.65	2.00e-124	439.00
IUUC-Bra-017483	Brassica rapa	59.77	2.00e-124	438.00
IUUC-Cel-018379	Caenorhabditis elegans	62.22	6.00e-145	506.00
IUUC-Cja-018956	Callithrix jacchus	98.59	0.00e+00	688.00
IUUC-Cfa-021064	Canis familiaris	98.02	0.00e+00	679.00
IUUC-Cpo-022443	Cavia porcellus	98.31	0.00e+00	686.00
IUUC-Cre-022711	Chlamydomonas reinhardtii	53.09	3.00e-98	351.00
IUUC-Csa-023841	Chlorocebus sabaeus	95.63	0.00e+00	690.00
IUUC-Cne-026900	Cryptococcus neoformans	42.28	1.00e-60	228.00
IUUC-Dre-028230	Danio rerio	91.35	0.00e+00	701.00
IUUC-Dno-029209	Dasypus novemcinctus	98.59	0.00e+00	686.00
IUUC-Dme-032038	Drosophila melanogaster	81.28	3.00e-100	358.00
IUUC-Eca-033721	Equus caballus	98.59	0.00e+00	688.00
IUUC-Eeu-034916	Erinaceus europaeus	97.28	1.00e-159	555.00
IUUC-Fca-036299	Felis catus	98.59	0.00e+00	687.00
IUUC-Fox-037682	Fusarium oxysporum	42.01	4.00e-73	269.00
IUUC-Fso-038299	Fusarium solani	37.07	3.00e-74	272.00
IUUC-Gmo-038611	Gadus morhua	94.63	0.00e+00	695.00
IUUC-Gga-041157	Gallus gallus	96.99	0.00e+00	700.00
IUUC-Gac-041764	Gasterosteus aculeatus	96.05	0.00e+00	701.00
IUUC-Gma-042927	Glycine max	60.66	3.00e-126	444.00
IUUC-Ggo-044659	Gorilla gorilla	98.59	0.00e+00	687.00
IUUC-Hsa-046156	Homo sapiens	95.63	0.00e+00	690.00
IUUC-Itr-048157	Ictidomys tridecemlineatus	95.63	0.00e+00	690.00
IUUC-Kpa-049250	Komagataella pastoris	44.83	2.00e-69	256.00
IUUC-Lch-049969	Latimeria chalumnae	93.72	0.00e+00	660.00
IUUC-Lpe-051368	Leersia perrieri	59.18	8.00e-122	429.00
IUUC-Loc-052479	Lepisosteus oculatus	88.80	0.00e+00	671.00
IUUC-Laf-054085	Loxodonta africana	95.63	0.00e+00	690.00
IUUC-Mcc-055566	Macaca mulatta	98.59	0.00e+00	689.00
IUUC-Mtr-057715	Medicago truncatula	60.11	2.00e-126	444.00
IUUC-Mla-059142	Melampsora laricipopulina	53.77	1.00e-94	340.00
IUUC-Mga-059575	Meleagris gallopavo	99.72	0.00e+00	697.00
IUUC-Mvi-060357	Microbotryum violaceum	53.96	5.00e-78	285.00
IUUC-Mdo-062579	Monodelphis domestica	95.63	0.00e+00	689.00
IUUC-Mmu-063611	Mus musculus	95.63	0.00e+00	690.00
IUUC-Mac-065323	Musa acuminata	60.11	1.00e-122	432.00
IUUC-Mpu-066038	Mustela putorius furo	98.59	0.00e+00	687.00
IUUC-Mlu-068183	Myotis lucifugus	98.31	0.00e+00	687.00
IUUC-Nle-069330	Nomascus leucogenys	95.63	0.00e+00	690.00
IUUC-Opr-070980	Ochotona princeps	98.31	0.00e+00	686.00
IUUC-Ont-072134	Oreochromis niloticus	92.68	0.00e+00	711.00
IUUC-Oan-073583	Ornithorhynchus anatinus	92.96	0.00e+00	682.00
IUUC-Ocu-074923	Oryctolagus cuniculus	98.59	0.00e+00	688.00
IUUC-Oba-075220	Oryza barthii	59.45	2.00e-122	431.00
IUUC-Obr-076208	Oryza brachyantha	56.83	9.00e-119	419.00
IUUC-Ogl-077216	Oryza glaberrima	59.45	2.00e-122	431.00
IUUC-Ogu-078836	Oryza glumaepatula	59.45	2.00e-122	431.00
IUUC-Oin-079522	Oryza indica	59.45	2.00e-122	431.00
IUUC-Olo-080882	Oryza longistaminata	59.45	2.00e-122	431.00
IUUC-Ome-081549	Oryza meridionalis	59.45	2.00e-122	431.00
IUUC-Oni-082982	Oryza nivara	59.45	2.00e-122	431.00
IUUC-Opu-083532	Oryza punctata	59.45	1.00e-122	432.00
IUUC-Oru-084568	Oryza rufipogon	59.45	2.00e-122	431.00
IUUC-Osa-085299	Oryza sativa	59.45	2.00e-122	431.00
IUUC-Ola-086546	Oryzias latipes	95.24	0.00e+00	705.00
IUUC-Oga-088073	Otolemur garnettii	98.59	0.00e+00	688.00
IUUC-Oar-089248	Ovis aries	98.59	0.00e+00	687.00
IUUC-Ptr-090814	Pan troglodytes	95.63	0.00e+00	690.00
IUUC-Pan-091753	Papio anubis	95.63	0.00e+00	690.00
IUUC-Psi-094012	Pelodiscus sinensis	98.33	0.00e+00	693.00
IUUC-Ppa-095415	Physcomitrella patens	58.49	8.00e-126	442.00
IUUC-Pfo-097369	Poecilia formosa	92.68	0.00e+00	711.00
IUUC-Pab-098594	Pongo abelii	98.31	0.00e+00	688.00
IUUC-Pop-099798	Populus trichocarpa	59.56	3.00e-125	441.00
IUUC-Pca-100913	Procavia capensis	81.79	4.00e-157	546.00
IUUC-Ppe-101474	Prunus persica	59.84	9.00e-126	442.00
IUUC-Pva-102892	Pteropus vampyrus	97.76	0.00e+00	688.00
IUUC-Rno-104909	Rattus norvegicus	95.36	0.00e+00	688.00
IUUC-Sce-106367	Saccharomyces cerevisiae	37.63	9.00e-56	211.00
IUUC-Sha-107400	Sarcophilus harrisii	97.77	0.00e+00	688.00
IUUC-Smo-109064	Selaginella moellendorffii	59.78	3.00e-120	424.00
IUUC-Sit-110819	Setaria italica	59.45	2.00e-123	434.00
IUUC-Sly-111210	Solanum lycopersicum	59.45	2.00e-125	441.00
IUUC-Stu-112398	Solanum tuberosum	59.62	7.00e-126	442.00
IUUC-Sbi-114724	Sorghum bicolor	59.18	3.00e-123	434.00
IUUC-Ssc-115550	Sus scrofa	98.59	0.00e+00	687.00
IUUC-Tgu-116800	Taeniopygia guttata	96.99	0.00e+00	699.00
IUUC-Tru-118212	Takifugu rubripes	92.68	0.00e+00	712.00
IUUC-Tni-120071	Tetraodon nigroviridis	92.68	0.00e+00	712.00
IUUC-Tca-121329	Theobroma cacao	59.56	1.00e-125	442.00
IUUC-Tae-124807	Triticum aestivum	59.18	1.00e-124	438.00
IUUC-Tur-126563	Triticum urartu	59.18	2.00e-124	438.00
IUUC-Tme-126890	Tuber melanosporum	46.49	1.00e-90	327.00
IUUC-Uma-129409	Ustilago maydis	48.78	3.00e-81	296.00
IUUC-Vpa-130590	Vicugna pacos	93.28	0.00e+00	644.00
IUUC-Vvi-131371	Vitis vinifera	59.67	2.00e-125	441.00
IUUC-Xma-133111	Xiphophorus maculatus	92.95	0.00e+00	711.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence