iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-021172

Ensembl Protein ID

ENSCAFP00000018771.3

UniProt Accession

E2RM60; E2RM60_CANLF

Genbank Protein ID

ENSCAFP00000018771

Protein Name

Ubiquitin-fold modifier-conjugating enzyme 1

Genbank Nucleotide ID

AAEX03018449

Gene Name

UFC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000012754.3	ENSCAFT00000020234.3	ENSCAFP00000018771.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E2/Other	98.80	3.00e-96	347.00	IUUC-Hsa-046948

Active Site

Position(s)	Description	Evidence
116	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR008716-1}

Organism

Canis familiaris

Functional Description
(View)

E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.

Protein Sequence
(Fasta)

MADEATRRVV SEIPVLKTNA GPRDRELWVQ RLKEEYQSLI RYVENNKNAD NDWFRLESNK 60
EGTRWFGKCW YIHDLLKYEF DIEFDIPVTY PATAPEIAVP ELDGKTAKMY RGGKICLTDH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGACG AGGCCACCCG GCGTGTGGTG TCTGAGATCC CTGTGCTGAA GACTAACGCC 60
GGACCTCGAG ATCGTGAGTT GTGGGTGCAG CGACTCAAGG AGGAATACCA GTCCCTCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR016135--UBQ-conjugating_enzyme/RWD
IPR014806--Ufc1

Pfam

PF08694--UFC1

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0071568--F:UFM1 transferase activity
GO:1990592--P:protein K69-linked ufmylation
GO:0034976--P:response to endoplasmic reticulum stress

KEGG

cfa:478978

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000219	Aegilops tauschii	69.62	1.00e-30	124.00
IUUC-Aml-001773	Ailuropoda melanoleuca	96.41	9.00e-96	342.00
IUUC-Atr-002519	Amborella trichopoda	67.08	2.00e-68	251.00
IUUC-Aca-004597	Anolis carolinensis	90.24	1.00e-88	317.00
IUUC-Aly-005549	Arabidopsis lyrata	66.67	2.00e-66	244.00
IUUC-Ath-007416	Arabidopsis thaliana	66.67	2.00e-66	244.00
IUUC-Ame-011281	Astyanax mexicanus	88.55	8.00e-88	315.00
IUUC-Bta-012940	Bos taurus	98.20	5.00e-97	345.00
IUUC-Bdi-014987	Brachypodium distachyon	63.58	4.00e-62	230.00
IUUC-Bol-016532	Brassica oleracea	67.28	9.00e-67	245.00
IUUC-Bra-017971	Brassica rapa	67.28	6.00e-67	246.00
IUUC-Cel-018620	Caenorhabditis elegans	71.25	9.00e-72	261.00
IUUC-Cja-019762	Callithrix jacchus	98.80	8.00e-97	345.00
IUUC-Cpo-021575	Cavia porcellus	98.20	8.00e-97	345.00
IUUC-Cre-022894	Chlamydomonas reinhardtii	60.62	2.00e-60	224.00
IUUC-Csa-024240	Chlorocebus sabaeus	94.61	4.00e-93	333.00
IUUC-Cho-024457	Choloepus hoffmanni	100.00	4.00e-29	120.00
IUUC-Cin-025708	Ciona intestinalis	76.22	2.00e-76	277.00
IUUC-Csv-026307	Ciona savignyi	76.83	1.00e-76	278.00
IUUC-Cgl-026671	Colletotrichum gloeosporioides	24.47	4.00e-02	32.00
IUUC-Dre-027752	Danio rerio	89.02	2.00e-88	317.00
IUUC-Dno-028957	Dasypus novemcinctus	97.90	4.00e-82	296.00
IUUC-Dor-030637	Dipodomys ordii	98.20	5.00e-97	346.00
IUUC-Dme-032033	Drosophila melanogaster	79.27	7.00e-81	292.00
IUUC-Ete-033056	Echinops telfairi	95.81	4.00e-95	339.00
IUUC-Eca-034260	Equus caballus	98.80	2.00e-97	347.00
IUUC-Eeu-034785	Erinaceus europaeus	58.18	1.00e-19	87.80
IUUC-Fca-035879	Felis catus	98.19	1.00e-95	341.00
IUUC-Gmo-039023	Gadus morhua	83.44	2.00e-85	307.00
IUUC-Gga-040475	Gallus gallus	84.72	3.00e-73	266.00
IUUC-Gac-041574	Gasterosteus aculeatus	79.27	6.00e-79	286.00
IUUC-Gma-043338	Glycine max	64.20	1.00e-65	241.00
IUUC-Ggo-044713	Gorilla gorilla	96.85	1.00e-72	264.00
IUUC-Hsa-046948	Homo sapiens	98.80	2.00e-97	347.00
IUUC-Hvu-047147	Hordeum vulgare	63.98	1.00e-61	229.00
IUUC-Itr-048742	Ictidomys tridecemlineatus	98.80	2.00e-97	347.00
IUUC-Lch-049654	Latimeria chalumnae	88.02	4.00e-89	319.00
IUUC-Lpe-051422	Leersia perrieri	63.98	3.00e-62	230.00
IUUC-Loc-051920	Lepisosteus oculatus	89.63	3.00e-89	320.00
IUUC-Laf-054338	Loxodonta africana	98.80	2.00e-97	347.00
IUUC-Mcc-054927	Macaca mulatta	98.80	2.00e-97	347.00
IUUC-Meu-056831	Macropus eugenii	95.73	3.00e-93	333.00
IUUC-Mtr-058091	Medicago truncatula	64.81	3.00e-65	240.00
IUUC-Mga-059933	Meleagris gallopavo	76.77	1.00e-44	170.00
IUUC-Mmr-061433	Microcebus murinus	100.00	4.00e-98	349.00
IUUC-Mdo-061994	Monodelphis domestica	95.12	1.00e-92	331.00
IUUC-Mmu-063398	Mus musculus	95.81	8.00e-96	342.00
IUUC-Mac-064536	Musa acuminata	63.58	6.00e-64	236.00
IUUC-Mpu-066795	Mustela putorius furo	98.20	5.00e-97	345.00
IUUC-Mlu-067983	Myotis lucifugus	96.41	3.00e-95	340.00
IUUC-Nle-069720	Nomascus leucogenys	98.20	2.00e-62	229.00
IUUC-Opr-070723	Ochotona princeps	98.20	5.00e-97	345.00
IUUC-Ont-071509	Oreochromis niloticus	81.10	9.00e-81	291.00
IUUC-Oan-073541	Ornithorhynchus anatinus	83.02	3.00e-23	99.40
IUUC-Ocu-074044	Oryctolagus cuniculus	98.78	3.00e-95	340.00
IUUC-Oba-075612	Oryza barthii	63.58	3.00e-62	230.00
IUUC-Obr-076432	Oryza brachyantha	63.58	3.00e-62	230.00
IUUC-Ogl-077071	Oryza glaberrima	63.58	3.00e-62	230.00
IUUC-Ogu-078427	Oryza glumaepatula	63.58	3.00e-62	230.00
IUUC-Oin-079963	Oryza indica	63.58	3.00e-62	230.00
IUUC-Olo-080455	Oryza longistaminata	63.58	3.00e-62	230.00
IUUC-Oni-082562	Oryza nivara	63.58	3.00e-62	230.00
IUUC-Opu-083688	Oryza punctata	63.35	9.00e-62	229.00
IUUC-Oru-084472	Oryza rufipogon	63.58	3.00e-62	230.00
IUUC-Osa-085623	Oryza sativa	63.58	3.00e-62	230.00
IUUC-Oga-088366	Otolemur garnettii	98.80	2.00e-97	347.00
IUUC-Oar-089754	Ovis aries	98.80	2.00e-97	347.00
IUUC-Ptr-090679	Pan troglodytes	98.20	4.00e-97	346.00
IUUC-Psi-093472	Pelodiscus sinensis	93.55	3.00e-68	249.00
IUUC-Ppa-095568	Physcomitrella patens	68.52	3.00e-68	250.00
IUUC-Pfo-097314	Poecilia formosa	80.49	6.00e-80	289.00
IUUC-Pab-098562	Pongo abelii	98.20	5.00e-97	345.00
IUUC-Pop-099506	Populus trichocarpa	64.81	2.00e-65	241.00
IUUC-Pca-101030	Procavia capensis	89.76	3.00e-85	306.00
IUUC-Ppe-101757	Prunus persica	66.05	3.00e-66	243.00
IUUC-Pva-102948	Pteropus vampyrus	97.60	1.00e-96	344.00
IUUC-Rno-105014	Rattus norvegicus	97.01	2.00e-96	344.00
IUUC-Sha-107297	Sarcophilus harrisii	94.61	2.00e-94	337.00
IUUC-Sit-110317	Setaria italica	62.96	2.00e-61	228.00
IUUC-Sly-111332	Solanum lycopersicum	66.05	7.00e-66	242.00
IUUC-Stu-112719	Solanum tuberosum	66.05	7.00e-66	242.00
IUUC-Sbi-114869	Sorghum bicolor	62.96	2.00e-61	228.00
IUUC-Ssc-116009	Sus scrofa	98.80	2.00e-97	347.00
IUUC-Tru-117527	Takifugu rubripes	82.93	5.00e-82	296.00
IUUC-Tsy-119195	Tarsius syrichta	95.74	1.00e-76	278.00
IUUC-Tni-120417	Tetraodon nigroviridis	81.10	6.00e-81	292.00
IUUC-Tca-120972	Theobroma cacao	67.28	1.00e-66	245.00
IUUC-Tae-124763	Triticum aestivum	63.98	2.00e-61	228.00
IUUC-Tur-126831	Triticum urartu	63.98	1.00e-61	229.00
IUUC-Tbe-128019	Tupaia belangeri	98.58	2.00e-81	293.00
IUUC-Ttr-129013	Tursiops truncatus	98.20	5.00e-97	345.00
IUUC-Vvi-131214	Vitis vinifera	65.43	6.00e-65	239.00
IUUC-Xtr-132182	Xenopus tropicalis	89.02	1.00e-88	317.00
IUUC-Xma-133877	Xiphophorus maculatus	80.49	8.00e-80	288.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence