iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091458

UUCD1 version

UUC-PaT-00066

Ensembl Protein ID

ENSPTRP00000023475.2

UniProt Accession

G2HFJ0; G2HFJ0_PANTR

Genbank Protein ID

BAK62498.1; JAA07771.1; JAA07772.1; JAA13252.1; JAA29438.1; JAA29439.1; JAA34053.1; JAA34054.1

Protein Name

Aurora kinase A; Serine/threonine-protein kinase 6

Genbank Nucleotide ID

AACZ03123744; GABC01003567; GABC01003566; GABF01008893; GABD01003662; GABD01003661; GABE01010686; GABE01010685

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000013646.3	ENSPTRT00000025431.2	ENSPTRP00000023475.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	99.75	0.00e+00	835.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MDRSKENCIS GPVKATAPVG GPKRVLVTQQ FPCQNPLPVN SGQAQRVLCP SNSSQRVPLQ 60
AQKLVSSHKP VQNQKQKQLQ ATSVPHPVSR PLNNTQKSKQ PLPSAPENNP EEELASKQKN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAAGGCAGC CTCGCTCGAG CGCAGGCCAA TCGGCTTTCT GGCTAGAGGG TTTAACTCCT 60
ATTTAAAAAG AAGAACCTTT GAATTCTAAC GGCTGAGCTC TTGGAAGACT TGGGTCCTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR030611--AURKA
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0032133--C:chromosome passenger complex
GO:0000780--C:condensed nuclear chromosome, centromeric region
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0051233--C:spindle midzone
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0032465--P:regulation of cytokinesis
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

KEGG

ptr:469980

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	63.80	1.00e-103	369.00
IUUC-Aml-001426	Ailuropoda melanoleuca	92.51	0.00e+00	737.00
IUUC-Atr-002453	Amborella trichopoda	64.01	6.00e-108	383.00
IUUC-Apl-003626	Anas platyrhynchos	71.50	1.00e-154	539.00
IUUC-Aca-004602	Anolis carolinensis	66.75	1.00e-148	519.00
IUUC-Aly-005878	Arabidopsis lyrata	64.68	5.00e-105	373.00
IUUC-Ath-007117	Arabidopsis thaliana	65.43	1.00e-105	375.00
IUUC-Acl-008199	Aspergillus clavatus	50.62	6.00e-88	317.00
IUUC-Afl-008419	Aspergillus flavus	56.20	8.00e-87	313.00
IUUC-Afu-008751	Aspergillus fumigatus	50.30	2.00e-87	316.00
IUUC-Ani-009181	Aspergillus nidulans	46.05	3.00e-90	325.00
IUUC-Ang-009787	Aspergillus niger	49.55	5.00e-88	317.00
IUUC-Aor-009980	Aspergillus oryzae	56.20	8.00e-87	313.00
IUUC-Ate-010286	Aspergillus terreus	50.00	4.00e-87	314.00
IUUC-Ame-010849	Astyanax mexicanus	57.91	2.00e-128	451.00
IUUC-Bgr-012110	Blumeria graminis	59.15	3.00e-89	322.00
IUUC-Bta-013474	Bos taurus	89.08	0.00e+00	731.00
IUUC-Bci-013756	Botrytis cinerea	53.29	7.00e-95	340.00
IUUC-Bdi-014257	Brachypodium distachyon	63.60	5.00e-105	373.00
IUUC-Bol-016310	Brassica oleracea	61.25	9.00e-103	366.00
IUUC-Bra-017438	Brassica rapa	61.25	4.00e-104	370.00
IUUC-Cel-018157	Caenorhabditis elegans	61.23	4.00e-101	360.00
IUUC-Cja-019282	Callithrix jacchus	96.28	0.00e+00	771.00
IUUC-Cfa-020162	Canis familiaris	90.70	0.00e+00	728.00
IUUC-Cpo-021764	Cavia porcellus	84.52	0.00e+00	676.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	66.92	3.00e-107	381.00
IUUC-Csa-023694	Chlorocebus sabaeus	97.27	0.00e+00	730.00
IUUC-Cho-024350	Choloepus hoffmanni	96.43	4.00e-113	400.00
IUUC-Cin-025542	Ciona intestinalis	70.33	3.00e-117	414.00
IUUC-Csv-025873	Ciona savignyi	69.96	2.00e-117	414.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	50.47	1.00e-83	303.00
IUUC-Cne-026928	Cryptococcus neoformans	61.09	1.00e-94	339.00
IUUC-Cme-027336	Cyanidioschyzon merolae	60.65	2.00e-119	422.00
IUUC-Dre-028198	Danio rerio	61.22	3.00e-131	461.00
IUUC-Dno-029928	Dasypus novemcinctus	87.60	0.00e+00	654.00
IUUC-Dor-030238	Dipodomys ordii	79.26	0.00e+00	641.00
IUUC-Dse-031266	Dothistroma septosporum	59.93	2.00e-92	332.00
IUUC-Dme-032007	Drosophila melanogaster	61.83	2.00e-100	358.00
IUUC-Ete-032911	Echinops telfairi	68.34	1.00e-134	472.00
IUUC-Eca-033749	Equus caballus	92.51	0.00e+00	729.00
IUUC-Eeu-035170	Erinaceus europaeus	87.65	0.00e+00	721.00
IUUC-Fca-035498	Felis catus	91.05	0.00e+00	726.00
IUUC-Fal-037397	Ficedula albicollis	67.87	6.00e-149	520.00
IUUC-Fox-037747	Fusarium oxysporum	51.03	6.00e-92	330.00
IUUC-Fso-038429	Fusarium solani	52.98	2.00e-91	328.00
IUUC-Gmo-039378	Gadus morhua	58.65	1.00e-124	439.00
IUUC-Ggr-039939	Gaeumannomyces graminis	58.28	9.00e-97	347.00
IUUC-Gga-040187	Gallus gallus	71.32	2.00e-152	531.00
IUUC-Gac-042223	Gasterosteus aculeatus	60.31	6.00e-131	460.00
IUUC-Gma-042870	Glycine max	62.94	3.00e-99	354.00
IUUC-Ggo-045617	Gorilla gorilla	99.50	0.00e+00	833.00
IUUC-Hsa-046968	Homo sapiens	99.75	0.00e+00	835.00
IUUC-Hvu-047072	Hordeum vulgare	53.09	1.00e-81	295.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	78.91	2.00e-180	624.00
IUUC-Kpa-049093	Komagataella pastoris	55.94	1.00e-76	279.00
IUUC-Lch-050346	Latimeria chalumnae	68.01	8.00e-146	509.00
IUUC-Lpe-051466	Leersia perrieri	64.08	2.00e-105	374.00
IUUC-Lma-053006	Leptosphaeria maculans	56.07	1.00e-89	322.00
IUUC-Laf-053422	Loxodonta africana	86.14	0.00e+00	707.00
IUUC-Mcc-055245	Macaca mulatta	97.73	0.00e+00	724.00
IUUC-Mor-056952	Magnaporthe oryzae	56.83	1.00e-91	329.00
IUUC-Mpo-057605	Magnaporthe poae	57.19	3.00e-97	348.00
IUUC-Mtr-057726	Medicago truncatula	64.00	4.00e-105	374.00
IUUC-Mla-059174	Melampsora laricipopulina	62.93	4.00e-98	351.00
IUUC-Mga-059562	Meleagris gallopavo	58.80	1.00e-117	416.00
IUUC-Mvi-060305	Microbotryum violaceum	61.60	1.00e-93	337.00
IUUC-Mmr-061588	Microcebus murinus	90.55	0.00e+00	756.00
IUUC-Mdo-061914	Monodelphis domestica	78.61	1.00e-177	615.00
IUUC-Mmu-063288	Mus musculus	82.43	0.00e+00	655.00
IUUC-Mac-064969	Musa acuminata	63.67	3.00e-106	377.00
IUUC-Mpu-066855	Mustela putorius furo	90.96	0.00e+00	724.00
IUUC-Mlu-068046	Myotis lucifugus	90.44	0.00e+00	716.00
IUUC-Nfi-068527	Neosartorya fischeri	50.30	3.00e-88	318.00
IUUC-Ncr-068678	Neurospora crassa	58.16	6.00e-94	337.00
IUUC-Nle-069848	Nomascus leucogenys	98.26	0.00e+00	823.00
IUUC-Opr-070589	Ochotona princeps	82.38	0.00e+00	647.00
IUUC-Ont-071733	Oreochromis niloticus	60.97	7.00e-125	440.00
IUUC-Oan-073399	Ornithorhynchus anatinus	86.44	2.00e-153	534.00
IUUC-Ocu-074063	Oryctolagus cuniculus	87.62	0.00e+00	723.00
IUUC-Oba-075264	Oryza barthii	63.67	1.00e-105	375.00
IUUC-Obr-076048	Oryza brachyantha	63.64	9.00e-105	372.00
IUUC-Ogl-077637	Oryza glaberrima	66.42	4.00e-104	370.00
IUUC-Ogu-078830	Oryza glumaepatula	63.67	1.00e-105	375.00
IUUC-Oin-079150	Oryza indica	63.67	6.00e-106	376.00
IUUC-Olo-080398	Oryza longistaminata	57.68	1.00e-82	299.00
IUUC-Ome-081544	Oryza meridionalis	54.41	2.00e-90	325.00
IUUC-Oni-082250	Oryza nivara	63.67	6.00e-106	376.00
IUUC-Opu-083638	Oryza punctata	64.69	2.00e-106	378.00
IUUC-Oru-084981	Oryza rufipogon	63.67	3.00e-106	377.00
IUUC-Osa-085961	Oryza sativa	63.67	3.00e-106	377.00
IUUC-Olu-087880	Ostreococcus lucimarinus	69.96	4.00e-112	397.00
IUUC-Oga-088891	Otolemur garnettii	90.65	0.00e+00	726.00
IUUC-Oar-090021	Ovis aries	88.83	0.00e+00	709.00
IUUC-Pan-092546	Papio anubis	97.27	0.00e+00	733.00
IUUC-Psi-093280	Pelodiscus sinensis	75.33	2.00e-161	561.00
IUUC-Pma-094298	Petromyzon marinus	76.60	6.00e-121	426.00
IUUC-Pno-094847	Phaeosphaeria nodorum	59.40	3.00e-89	321.00
IUUC-Ppa-095855	Physcomitrella patens	65.93	4.00e-108	384.00
IUUC-Pfo-096428	Poecilia formosa	60.84	1.00e-128	452.00
IUUC-Pab-098696	Pongo abelii	97.77	0.00e+00	803.00
IUUC-Pop-099405	Populus trichocarpa	61.59	4.00e-106	377.00
IUUC-Pca-100740	Procavia capensis	81.68	0.00e+00	673.00
IUUC-Ppe-101854	Prunus persica	63.19	9.00e-107	379.00
IUUC-Pva-103212	Pteropus vampyrus	89.15	0.00e+00	703.00
IUUC-Pgr-103474	Puccinia graminis	62.88	4.00e-98	351.00
IUUC-Ptt-103933	Puccinia triticina	49.03	1.00e-61	229.00
IUUC-Pte-104089	Pyrenophora teres	47.73	1.00e-90	326.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	47.73	1.00e-90	326.00
IUUC-Rno-105057	Rattus norvegicus	83.66	0.00e+00	668.00
IUUC-Sha-107137	Sarcophilus harrisii	80.10	3.00e-180	624.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	57.34	9.00e-99	353.00
IUUC-Spo-108078	Schizosaccharomyces pombe	61.09	3.00e-101	361.00
IUUC-Smo-109288	Selaginella moellendorffii	63.67	7.00e-108	383.00
IUUC-Sit-110246	Setaria italica	63.32	4.00e-106	377.00
IUUC-Sly-111379	Solanum lycopersicum	64.73	5.00e-106	377.00
IUUC-Stu-112777	Solanum tuberosum	61.25	3.00e-106	377.00
IUUC-Sbi-114325	Sorghum bicolor	64.52	3.00e-105	374.00
IUUC-Sre-115203	Sporisorium reilianum	58.65	1.00e-80	293.00
IUUC-Ssc-115361	Sus scrofa	88.83	0.00e+00	724.00
IUUC-Tgu-116967	Taeniopygia guttata	72.51	8.00e-148	516.00
IUUC-Tru-117570	Takifugu rubripes	62.07	2.00e-139	488.00
IUUC-Tsy-119280	Tarsius syrichta	70.47	2.00e-150	525.00
IUUC-Tni-120721	Tetraodon nigroviridis	62.69	4.00e-135	474.00
IUUC-Tca-121494	Theobroma cacao	61.67	2.00e-105	375.00
IUUC-Tre-121869	Trichoderma reesei	55.38	7.00e-96	343.00
IUUC-Tvi-122510	Trichoderma virens	56.90	6.00e-94	337.00
IUUC-Tae-123071	Triticum aestivum	63.80	1.00e-103	369.00
IUUC-Tur-126240	Triticum urartu	63.80	4.00e-103	367.00
IUUC-Tme-126921	Tuber melanosporum	60.29	5.00e-96	344.00
IUUC-Tbe-127872	Tupaia belangeri	84.99	0.00e+00	649.00
IUUC-Ttr-129134	Tursiops truncatus	89.66	0.00e+00	684.00
IUUC-Uma-129412	Ustilago maydis	59.25	2.00e-79	289.00
IUUC-Vda-130003	Verticillium dahliae	50.44	2.00e-94	338.00
IUUC-Vvi-131272	Vitis vinifera	63.64	3.00e-106	377.00
IUUC-Xtr-132019	Xenopus tropicalis	65.42	2.00e-148	518.00
IUUC-Xma-134203	Xiphophorus maculatus	61.06	3.00e-134	471.00
IUUC-Yli-134503	Yarrowia lipolytica	53.85	6.00e-86	310.00
IUUC-Zma-135232	Zea mays	61.82	3.00e-106	377.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence