iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098518

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Anaphase-promoting complex subunit 5; Cyclosome subunit 5

Genbank Nucleotide ID

CR857685

Gene Name

ANAPC5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000005048.2	ENSPPYT00000005971.2	ENSPPYP00000005751.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/APC_C/APC_C	100.00	0.00e+00	1485.00	IUUC-Hsa-047014
E3 adaptor/Cullin RING/APC_C/APC_C	29.63	4.30e-02	35.00	IUUC-Sce-106345

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pongo abelii

Functional Description
(View)

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).

Protein Sequence
(Fasta)

MASVHESLYF NPMMTNGVVH ANVFGIKDWV TPYKIAVLVL LNEMSRTGEG AVSLMERRRL 60
NQLLLPLLQG PDITLSKLYK LIEESCPQLA NSVQIRIKLM AEGELKDMEQ FFDDLSDSFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGACTGCT CTGATTGGTT AACAACATGC CGCGAGCACG CAGATGTCTG TTTCCTGGGA 60
TACTGTGAGG GCGGGCGGAG ATGTGGACCC GGTAGTGTTG TGCCTTGTGA AAACTGGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0498--Mitosis
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat
KW-0833--Ubl conjugation pathway

Interpro

IPR026000--Apc5_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat

Pfam

PF12862--ANAPC5

SMART

SM00028--TPR

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0051301--P:cell division
GO:0007067--P:mitotic nuclear division
GO:0070979--P:protein K11-linked ubiquitination

KEGG

pon:100171787

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000646	Aegilops tauschii	26.49	7.00e-13	69.30
IUUC-Aml-001228	Ailuropoda melanoleuca	96.96	0.00e+00	1425.00
IUUC-Atr-003077	Amborella trichopoda	35.71	4.00e-04	36.20
IUUC-Apl-003267	Anas platyrhynchos	86.02	0.00e+00	1308.00
IUUC-Aly-005908	Arabidopsis lyrata	26.16	9.00e-13	69.30
IUUC-Ath-007298	Arabidopsis thaliana	26.67	6.00e-13	69.70
IUUC-Acl-008249	Aspergillus clavatus	25.91	3.00e-15	77.00
IUUC-Afl-008627	Aspergillus flavus	22.87	5.00e-17	82.80
IUUC-Afu-008849	Aspergillus fumigatus	27.34	9.00e-16	79.00
IUUC-Ani-009400	Aspergillus nidulans	22.89	2.00e-11	64.70
IUUC-Ang-009751	Aspergillus niger	27.41	4.00e-16	80.10
IUUC-Aor-010070	Aspergillus oryzae	29.54	6.00e-16	78.60
IUUC-Ate-010499	Aspergillus terreus	26.94	5.00e-18	86.30
IUUC-Ame-011897	Astyanax mexicanus	63.61	0.00e+00	906.00
IUUC-Bgr-012227	Blumeria graminis	26.64	1.00e-12	68.60
IUUC-Bta-013451	Bos taurus	97.22	0.00e+00	1416.00
IUUC-Bci-013682	Botrytis cinerea	22.20	4.00e-15	77.00
IUUC-Bdi-014911	Brachypodium distachyon	26.32	1.00e-14	75.10
IUUC-Bol-015869	Brassica oleracea	26.09	8.00e-13	69.30
IUUC-Bra-017532	Brassica rapa	25.87	5.00e-12	66.60
IUUC-Cel-018109	Caenorhabditis elegans	21.04	7.00e-06	45.80
IUUC-Cja-019568	Callithrix jacchus	98.94	0.00e+00	1467.00
IUUC-Cfa-020050	Canis familiaris	97.88	0.00e+00	1432.00
IUUC-Cpo-021705	Cavia porcellus	92.61	0.00e+00	1354.00
IUUC-Csa-023099	Chlorocebus sabaeus	98.28	0.00e+00	1451.00
IUUC-Cho-024968	Choloepus hoffmanni	83.21	0.00e+00	665.00
IUUC-Cin-025286	Ciona intestinalis	28.43	3.00e-28	119.00
IUUC-Cgl-026397	Colletotrichum gloeosporioides	27.53	1.00e-13	72.00
IUUC-Dre-028446	Danio rerio	65.62	0.00e+00	949.00
IUUC-Dno-029248	Dasypus novemcinctus	96.29	0.00e+00	1405.00
IUUC-Dor-030713	Dipodomys ordii	90.23	0.00e+00	1177.00
IUUC-Dse-031480	Dothistroma septosporum	28.87	1.00e-05	45.10
IUUC-Dme-031636	Drosophila melanogaster	27.61	5.00e-38	152.00
IUUC-Ete-032483	Echinops telfairi	95.36	0.00e+00	1405.00
IUUC-Eca-033381	Equus caballus	98.15	0.00e+00	1436.00
IUUC-Eeu-034557	Erinaceus europaeus	70.98	0.00e+00	684.00
IUUC-Fca-035995	Felis catus	99.27	0.00e+00	1068.00
IUUC-Fal-037344	Ficedula albicollis	85.92	0.00e+00	1273.00
IUUC-Fox-038064	Fusarium oxysporum	20.82	1.00e-10	61.60
IUUC-Fso-038085	Fusarium solani	23.54	8.00e-13	68.90
IUUC-Ggr-040022	Gaeumannomyces graminis	23.83	2.00e-09	58.20
IUUC-Gga-040306	Gallus gallus	85.41	0.00e+00	1295.00
IUUC-Gac-042229	Gasterosteus aculeatus	66.23	0.00e+00	951.00
IUUC-Gma-042708	Glycine max	29.72	2.00e-14	75.10
IUUC-Ggo-045040	Gorilla gorilla	99.87	0.00e+00	1483.00
IUUC-Hsa-047014	Homo sapiens	100.00	0.00e+00	1485.00
IUUC-Hvu-047209	Hordeum vulgare	25.92	5.00e-15	76.60
IUUC-Itr-047936	Ictidomys tridecemlineatus	97.49	0.00e+00	841.00
IUUC-Lch-049595	Latimeria chalumnae	77.48	0.00e+00	1143.00
IUUC-Lpe-051682	Leersia perrieri	25.72	1.00e-14	75.50
IUUC-Loc-052640	Lepisosteus oculatus	72.89	0.00e+00	1086.00
IUUC-Lma-052954	Leptosphaeria maculans	24.32	2.00e-04	41.20
IUUC-Laf-054391	Loxodonta africana	97.04	0.00e+00	1380.00
IUUC-Mcc-055384	Macaca mulatta	100.00	0.00e+00	1485.00
IUUC-Meu-056410	Macropus eugenii	82.74	0.00e+00	766.00
IUUC-Mor-057156	Magnaporthe oryzae	20.81	2.00e-10	61.20
IUUC-Mpo-057453	Magnaporthe poae	34.31	7.00e-10	58.90
IUUC-Mtr-058102	Medicago truncatula	27.27	1.00e-12	68.60
IUUC-Mla-059063	Melampsora laricipopulina	35.29	8.00e-04	38.90
IUUC-Mga-059991	Meleagris gallopavo	86.96	0.00e+00	1207.00
IUUC-Mmr-060939	Microcebus murinus	95.76	0.00e+00	1381.00
IUUC-Mdo-062775	Monodelphis domestica	89.68	0.00e+00	1339.00
IUUC-Mmu-063110	Mus musculus	94.35	0.00e+00	1405.00
IUUC-Mac-065555	Musa acuminata	29.11	4.00e-15	77.00
IUUC-Mpu-066382	Mustela putorius furo	97.96	0.00e+00	1322.00
IUUC-Mlu-067724	Myotis lucifugus	91.52	0.00e+00	1315.00
IUUC-Nfi-068251	Neosartorya fischeri	27.54	8.00e-16	79.00
IUUC-Ncr-068757	Neurospora crassa	21.87	6.00e-13	69.70
IUUC-Nle-069022	Nomascus leucogenys	100.00	0.00e+00	1485.00
IUUC-Opr-070727	Ochotona princeps	94.80	0.00e+00	1051.00
IUUC-Ont-071409	Oreochromis niloticus	65.67	0.00e+00	967.00
IUUC-Oan-073732	Ornithorhynchus anatinus	91.32	0.00e+00	806.00
IUUC-Oba-075329	Oryza barthii	24.36	4.00e-12	67.40
IUUC-Obr-076176	Oryza brachyantha	25.00	3.00e-15	77.80
IUUC-Ogl-076949	Oryza glaberrima	25.66	3.00e-15	77.40
IUUC-Ogu-078835	Oryza glumaepatula	24.36	4.00e-12	67.40
IUUC-Oin-079783	Oryza indica	25.34	1.00e-12	68.60
IUUC-Olo-080921	Oryza longistaminata	24.36	9.00e-12	66.20
IUUC-Ome-081983	Oryza meridionalis	24.80	1.00e-14	76.30
IUUC-Oni-082649	Oryza nivara	24.36	4.00e-12	67.40
IUUC-Opu-083962	Oryza punctata	25.88	2.00e-15	78.20
IUUC-Oru-085221	Oryza rufipogon	24.36	4.00e-12	67.40
IUUC-Osa-086035	Oryza sativa	25.61	5.00e-15	77.00
IUUC-Ola-087386	Oryzias latipes	65.58	0.00e+00	957.00
IUUC-Olu-087848	Ostreococcus lucimarinus	24.09	9.00e-05	42.40
IUUC-Oga-089166	Otolemur garnettii	96.56	0.00e+00	1384.00
IUUC-Oar-090437	Ovis aries	96.96	0.00e+00	1409.00
IUUC-Ptr-090917	Pan troglodytes	100.00	0.00e+00	1485.00
IUUC-Pan-091739	Papio anubis	99.34	0.00e+00	1451.00
IUUC-Psi-093776	Pelodiscus sinensis	86.42	0.00e+00	1212.00
IUUC-Pma-094696	Petromyzon marinus	35.09	1.00e-43	170.00
IUUC-Pno-094995	Phaeosphaeria nodorum	23.35	7.00e-04	38.50
IUUC-Ppa-095754	Physcomitrella patens	35.66	8.00e-13	69.30
IUUC-Pfo-096997	Poecilia formosa	63.84	0.00e+00	930.00
IUUC-Pop-099568	Populus trichocarpa	24.28	3.00e-11	63.90
IUUC-Pca-100400	Procavia capensis	87.55	0.00e+00	1214.00
IUUC-Ppe-101627	Prunus persica	26.25	3.00e-16	80.90
IUUC-Pva-103252	Pteropus vampyrus	92.19	0.00e+00	1359.00
IUUC-Pte-104302	Pyrenophora teres	23.44	2.00e-04	40.80
IUUC-Pyt-104585	Pyrenophora triticirepentis	23.37	9.00e-05	42.40
IUUC-Rno-104876	Rattus norvegicus	94.75	0.00e+00	1408.00
IUUC-Sce-106345	Saccharomyces cerevisiae	28.57	1.80e-02	34.70
IUUC-Sha-107267	Sarcophilus harrisii	88.08	0.00e+00	1092.00
IUUC-Sja-107719	Schizosaccharomyces japonicus	26.50	7.00e-11	62.80
IUUC-Spo-108363	Schizosaccharomyces pombe	25.88	5.00e-09	56.60
IUUC-Ssl-108557	Sclerotinia sclerotiorum	23.36	2.00e-10	61.20
IUUC-Smo-109037	Selaginella moellendorffii	25.22	8.00e-14	72.40
IUUC-Sit-110705	Setaria italica	26.19	3.00e-15	77.40
IUUC-Sly-111864	Solanum lycopersicum	32.37	1.00e-11	65.90
IUUC-Sar-113485	Sorex araneus	87.42	0.00e+00	1315.00
IUUC-Sbi-114673	Sorghum bicolor	25.72	2.00e-15	77.80
IUUC-Sre-115155	Sporisorium reilianum	40.38	4.00e-03	37.00
IUUC-Ssc-115301	Sus scrofa	97.09	0.00e+00	1453.00
IUUC-Tgu-116928	Taeniopygia guttata	86.21	0.00e+00	1282.00
IUUC-Tru-117756	Takifugu rubripes	63.98	0.00e+00	897.00
IUUC-Tsy-119155	Tarsius syrichta	82.12	0.00e+00	1197.00
IUUC-Tni-120285	Tetraodon nigroviridis	63.85	0.00e+00	884.00
IUUC-Tca-121305	Theobroma cacao	24.92	1.00e-12	68.60
IUUC-Tre-122123	Trichoderma reesei	25.34	8.00e-13	68.90
IUUC-Tvi-122313	Trichoderma virens	24.49	1.00e-12	68.90
IUUC-Tae-125147	Triticum aestivum	26.70	1.00e-15	78.60
IUUC-Tur-126507	Triticum urartu	26.68	9.00e-16	79.30
IUUC-Tme-127132	Tuber melanosporum	21.88	3.00e-17	84.00
IUUC-Tbe-127653	Tupaia belangeri	83.12	0.00e+00	759.00
IUUC-Ttr-129200	Tursiops truncatus	96.29	0.00e+00	1419.00
IUUC-Uma-129658	Ustilago maydis	25.81	7.00e-04	39.30
IUUC-Vda-129916	Verticillium dahliae	21.65	8.00e-10	59.30
IUUC-Vpa-130494	Vicugna pacos	89.57	0.00e+00	1147.00
IUUC-Vvi-131317	Vitis vinifera	31.21	6.00e-10	58.90
IUUC-Xtr-132765	Xenopus tropicalis	81.24	0.00e+00	1219.00
IUUC-Xma-133195	Xiphophorus maculatus	66.26	0.00e+00	807.00
IUUC-Yli-134672	Yarrowia lipolytica	45.28	5.00e-06	46.60
IUUC-Zma-135338	Zea mays	27.56	3.00e-16	80.90

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence