iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071518

Ensembl Protein ID

ENSONIP00000016562.1

UniProt Accession

I3K617; I3K617_ORENI

Genbank Protein ID

ENSONIP00000016562

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01004945

Gene Name

traf4a; traf4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000013167.1	ENSONIT00000016577.1	ENSONIP00000016562.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.90e-06	28.2	14	76

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrli 65
             f Cp+  + Mr+Pv ++ +G+ +  ++++++l++g  +cP ++ pl+  ++ P  +l + i
   Q: 14   RRFQCPLCSKAMREPVQVStCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEQQI 76
           67***************999*****************99*****************9998877 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MPGFDYKFLE KPKRRFQCPL CSKAMREPVQ VSTCGHRFCD TCLQEFLSEG VFKCPEDQLP 60
LDYAKIYPDP ELEQQILALP IRCIHSEEGC RWTGQMKQLQ GHFSTCAFNV IPCPNRCSVK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCGGGT TTGATTACAA GTTCCTGGAG AAGCCAAAGA GACGCTTCCA GTGTCCGCTC 60
TGCAGCAAAG CGATGCGGGA GCCGGTCCAA GTGTCCACCT GTGGACACCG CTTCTGTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027138--TRAF4
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00917--MATH
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0005622--C:intracellular
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0046330--P:positive regulation of JNK cascade
GO:0042981--P:regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001287	Ailuropoda melanoleuca	76.07	0.00e+00	749.00
IUUC-Ame-011530	Astyanax mexicanus	94.47	0.00e+00	909.00
IUUC-Bta-013582	Bos taurus	77.19	0.00e+00	765.00
IUUC-Bdi-014617	Brachypodium distachyon	25.18	9.00e-08	53.10
IUUC-Cfa-020133	Canis familiaris	73.13	0.00e+00	706.00
IUUC-Cpo-022021	Cavia porcellus	77.61	0.00e+00	773.00
IUUC-Csa-023199	Chlorocebus sabaeus	77.40	0.00e+00	771.00
IUUC-Dre-028193	Danio rerio	95.74	0.00e+00	917.00
IUUC-Dno-028917	Dasypus novemcinctus	77.83	0.00e+00	775.00
IUUC-Ete-032433	Echinops telfairi	76.55	0.00e+00	761.00
IUUC-Fca-036155	Felis catus	77.40	0.00e+00	769.00
IUUC-Gmo-038860	Gadus morhua	96.38	0.00e+00	921.00
IUUC-Gga-041052	Gallus gallus	82.52	0.00e+00	846.00
IUUC-Gac-041489	Gasterosteus aculeatus	98.51	0.00e+00	931.00
IUUC-Gma-043859	Glycine max	30.40	9.00e-07	50.10
IUUC-Ggo-044996	Gorilla gorilla	77.40	0.00e+00	770.00
IUUC-Hsa-046252	Homo sapiens	77.61	0.00e+00	773.00
IUUC-Hvu-047095	Hordeum vulgare	26.45	1.00e-07	52.80
IUUC-Itr-048232	Ictidomys tridecemlineatus	77.83	0.00e+00	775.00
IUUC-Kpa-049340	Komagataella pastoris	27.80	6.00e-16	79.00
IUUC-Loc-052312	Lepisosteus oculatus	91.30	0.00e+00	884.00
IUUC-Laf-054376	Loxodonta africana	77.61	0.00e+00	770.00
IUUC-Mcc-055684	Macaca mulatta	77.40	0.00e+00	771.00
IUUC-Mmr-061198	Microcebus murinus	77.83	0.00e+00	775.00
IUUC-Mdo-062585	Monodelphis domestica	76.97	0.00e+00	766.00
IUUC-Mmu-064303	Mus musculus	76.97	0.00e+00	769.00
IUUC-Mac-064547	Musa acuminata	28.10	7.00e-07	50.10
IUUC-Mpu-066854	Mustela putorius furo	76.97	0.00e+00	765.00
IUUC-Nle-070098	Nomascus leucogenys	76.55	0.00e+00	762.00
IUUC-Ocu-073841	Oryctolagus cuniculus	77.19	0.00e+00	769.00
IUUC-Ola-086674	Oryzias latipes	98.30	0.00e+00	933.00
IUUC-Oga-088510	Otolemur garnettii	77.19	0.00e+00	768.00
IUUC-Oar-089225	Ovis aries	74.63	0.00e+00	730.00
IUUC-Pan-092725	Papio anubis	77.40	0.00e+00	771.00
IUUC-Pfo-096341	Poecilia formosa	98.51	0.00e+00	936.00
IUUC-Ppe-101708	Prunus persica	28.79	6.00e-08	53.90
IUUC-Pva-103131	Pteropus vampyrus	72.41	8.00e-111	394.00
IUUC-Rno-105996	Rattus norvegicus	77.19	0.00e+00	769.00
IUUC-Sly-111800	Solanum lycopersicum	31.93	3.00e-08	55.10
IUUC-Sbi-114841	Sorghum bicolor	27.27	1.00e-07	52.80
IUUC-Tru-117602	Takifugu rubripes	97.23	0.00e+00	925.00
IUUC-Tca-121454	Theobroma cacao	31.20	3.00e-07	52.00
IUUC-Tae-123531	Triticum aestivum	25.62	2.00e-07	52.00
IUUC-Tur-126325	Triticum urartu	26.45	9.00e-08	53.10
IUUC-Ttr-128370	Tursiops truncatus	78.61	2.00e-176	611.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence