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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063439
Ensembl Protein ID ENSMUSP00000022909.8
UniProt Accession Q6PAC3; E9QPL0; DCA13_MOUSE
Genbank Protein ID AAH60375.1
Protein Name DDB1- and CUL4-associated factor 13; WD repeat and SOF domain-containing protein 1
Genbank Nucleotide ID AC164883
Gene Name Dcaf13; Gm83; Wdsof1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000022300.9 ENSMUST00000022909.9 ENSMUSP00000022909.8
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarmiRNAMap
RAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
Mentha
Post-translational Modifications (PTMs)
PhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.70e-22 79.7 64 103
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sdtl...lvsGsdDgtikvWDlrtgvllk 37
           gH d+v+cla          ++sG+ Dg +k+W+l++ ++++
   Q: 64   GHRDGVNCLAKhpK--SlasVLSGACDGEVKIWNLTKRKCIR 103
           8********84442..2233788*************999987 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity).
 Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity).
Protein Sequence
(Fasta)
MKVKMLSRNP DNYVRETKLD IQRVPRNYDP TLHPFEVPRE YVRALNATKL ERVFAKPFLA 60
SLDGHRDGVN CLAKHPKSLA SVLSGACDGE VKIWNLTKRK CIRTIQAHEG FVRGMCTRFC 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063439|E3,WD_repeat|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TGCGGAGCCA CGTGACAGGA AGCCCGCGGA AGGCGGAAGT AGTGTGTCTG CGTGCTGGCC 60
CCGGTAAGTC GAGCCCGGTT TAAAGGCTCG TGGAGTCCGA CACCCAGAGC CGCCAAGATG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063439|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0687--Ribonucleoprotein
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat
Interpro

IPR007287--Sof1
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF04158--Sof1
PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0030054--C:cell junction
GO:0005813--C:centrosome
GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0032040--C:small-subunit processome
GO:0003723--F:RNA binding
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0016567--P:protein ubiquitination
KEGG mmu:223499
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002178 Ailuropoda melanoleuca 93.26 0.00e+00 884.00
IUUC-Atr-002799 Amborella trichopoda 47.35 2.00e-133 468.00
IUUC-Apl-003675 Anas platyrhynchos 83.63 0.00e+00 778.00
IUUC-Aca-004792 Anolis carolinensis 84.72 0.00e+00 829.00
IUUC-Aly-005998 Arabidopsis lyrata 46.46 3.00e-131 461.00
IUUC-Ath-007526 Arabidopsis thaliana 46.46 4.00e-131 461.00
IUUC-Ago-007774 Ashbya gossypii 46.77 3.00e-121 428.00
IUUC-Acl-008024 Aspergillus clavatus 43.50 8.00e-110 390.00
IUUC-Afu-008930 Aspergillus fumigatus 42.58 4.00e-108 385.00
IUUC-Ani-009370 Aspergillus nidulans 43.30 1.00e-108 386.00
IUUC-Ang-009827 Aspergillus niger 45.76 3.00e-113 401.00
IUUC-Aor-010060 Aspergillus oryzae 44.20 5.00e-106 377.00
IUUC-Ate-010434 Aspergillus terreus 45.86 4.00e-94 337.00
IUUC-Ame-011967 Astyanax mexicanus 74.20 0.00e+00 722.00
IUUC-Bgr-011989 Blumeria graminis 44.25 1.00e-110 392.00
IUUC-Bta-013291 Bos taurus 67.71 6.00e-180 623.00
IUUC-Bci-013868 Botrytis cinerea 43.02 4.00e-107 381.00
IUUC-Bdi-014343 Brachypodium distachyon 47.79 5.00e-126 444.00
IUUC-Bol-015740 Brassica oleracea 44.25 5.00e-121 427.00
IUUC-Bra-016689 Brassica rapa 44.25 3.00e-119 422.00
IUUC-Cel-018536 Caenorhabditis elegans 50.12 3.00e-123 435.00
IUUC-Cja-018779 Callithrix jacchus 93.93 0.00e+00 899.00
IUUC-Cfa-020105 Canis familiaris 94.61 0.00e+00 900.00
IUUC-Cpo-021538 Cavia porcellus 92.13 0.00e+00 858.00
IUUC-Cre-022798 Chlamydomonas reinhardtii 50.92 6.00e-47 179.00
IUUC-Csa-023492 Chlorocebus sabaeus 94.16 0.00e+00 897.00
IUUC-Cho-024497 Choloepus hoffmanni 81.19 7.00e-156 543.00
IUUC-Cin-025524 Ciona intestinalis 64.71 3.00e-176 610.00
IUUC-Csv-026197 Ciona savignyi 63.88 5.00e-176 610.00
IUUC-Cgl-026745 Colletotrichum gloeosporioides 40.31 9.00e-96 343.00
IUUC-Cne-026840 Cryptococcus neoformans 36.74 2.00e-81 298.00
IUUC-Cme-027111 Cyanidioschyzon merolae 35.13 6.00e-74 271.00
IUUC-Dre-027471 Danio rerio 75.58 0.00e+00 730.00
IUUC-Dno-029790 Dasypus novemcinctus 90.30 0.00e+00 694.00
IUUC-Dor-030971 Dipodomys ordii 76.18 0.00e+00 706.00
IUUC-Dse-031563 Dothistroma septosporum 45.01 1.00e-108 386.00
IUUC-Dme-032161 Drosophila melanogaster 59.28 2.00e-164 571.00
IUUC-Ete-033127 Echinops telfairi 86.80 0.00e+00 820.00
IUUC-Eca-033531 Equus caballus 92.92 0.00e+00 846.00
IUUC-Eeu-034663 Erinaceus europaeus 80.54 0.00e+00 739.00
IUUC-Fca-036258 Felis catus 94.83 0.00e+00 902.00
IUUC-Fal-037456 Ficedula albicollis 87.42 0.00e+00 796.00
IUUC-Fox-038025 Fusarium oxysporum 43.62 6.00e-106 377.00
IUUC-Fso-038344 Fusarium solani 42.67 1.00e-101 363.00
IUUC-Gmo-039643 Gadus morhua 77.53 0.00e+00 757.00
IUUC-Ggr-039816 Gaeumannomyces graminis 45.18 1.00e-104 373.00
IUUC-Gga-040143 Gallus gallus 87.42 0.00e+00 822.00
IUUC-Gac-041665 Gasterosteus aculeatus 78.29 0.00e+00 751.00
IUUC-Gma-043073 Glycine max 46.46 3.00e-127 448.00
IUUC-Ggo-045058 Gorilla gorilla 93.71 0.00e+00 895.00
IUUC-Hsa-046843 Homo sapiens 93.03 0.00e+00 890.00
IUUC-Hvu-047654 Hordeum vulgare 47.68 1.00e-74 273.00
IUUC-Itr-048822 Ictidomys tridecemlineatus 94.61 0.00e+00 904.00
IUUC-Kpa-049232 Komagataella pastoris 47.48 3.00e-124 438.00
IUUC-Lch-050542 Latimeria chalumnae 80.08 0.00e+00 806.00
IUUC-Lpe-051622 Leersia perrieri 48.23 9.00e-129 453.00
IUUC-Loc-052674 Lepisosteus oculatus 76.48 0.00e+00 739.00
IUUC-Lma-053108 Leptosphaeria maculans 44.20 1.00e-108 386.00
IUUC-Laf-053385 Loxodonta africana 93.48 0.00e+00 874.00
IUUC-Mcc-055151 Macaca mulatta 93.71 0.00e+00 895.00
IUUC-Meu-056230 Macropus eugenii 88.57 4.00e-118 417.00
IUUC-Mor-057013 Magnaporthe oryzae 43.49 9.00e-101 360.00
IUUC-Mpo-057530 Magnaporthe poae 45.18 1.00e-105 376.00
IUUC-Mtr-058187 Medicago truncatula 47.12 2.00e-128 452.00
IUUC-Mla-058964 Melampsora laricipopulina 39.51 2.00e-93 335.00
IUUC-Mga-059712 Meleagris gallopavo 87.44 0.00e+00 782.00
IUUC-Mvi-060370 Microbotryum violaceum 32.85 3.00e-72 265.00
IUUC-Mmr-061340 Microcebus murinus 88.86 0.00e+00 835.00
IUUC-Mdo-062978 Monodelphis domestica 87.19 0.00e+00 840.00
IUUC-Mac-065129 Musa acuminata 47.32 5.00e-134 471.00
IUUC-Mpu-066548 Mustela putorius furo 84.16 0.00e+00 694.00
IUUC-Mlu-067660 Myotis lucifugus 94.16 0.00e+00 899.00
IUUC-Nfi-068455 Neosartorya fischeri 43.95 3.00e-111 395.00
IUUC-Ncr-068848 Neurospora crassa 42.23 2.00e-97 349.00
IUUC-Nle-069923 Nomascus leucogenys 93.71 0.00e+00 893.00
IUUC-Opr-070279 Ochotona princeps 81.05 9.00e-90 323.00
IUUC-Ont-072234 Oreochromis niloticus 78.20 0.00e+00 769.00
IUUC-Oan-073713 Ornithorhynchus anatinus 84.54 8.00e-103 365.00
IUUC-Ocu-073782 Oryctolagus cuniculus 94.61 0.00e+00 900.00
IUUC-Oba-075161 Oryza barthii 48.23 3.00e-129 455.00
IUUC-Obr-076868 Oryza brachyantha 48.23 3.00e-128 451.00
IUUC-Ogl-077062 Oryza glaberrima 48.23 3.00e-129 455.00
IUUC-Ogu-078308 Oryza glumaepatula 48.23 3.00e-129 455.00
IUUC-Oin-079378 Oryza indica 48.23 3.00e-129 455.00
IUUC-Olo-080638 Oryza longistaminata 45.58 1.00e-117 416.00
IUUC-Oni-082368 Oryza nivara 48.23 3.00e-129 455.00
IUUC-Opu-083628 Oryza punctata 48.23 3.00e-129 455.00
IUUC-Oru-085226 Oryza rufipogon 48.01 8.00e-129 453.00
IUUC-Osa-085368 Oryza sativa 44.11 5.00e-69 254.00
IUUC-Ola-086836 Oryzias latipes 80.00 0.00e+00 782.00
IUUC-Olu-087755 Ostreococcus lucimarinus 45.77 7.00e-126 444.00
IUUC-Oga-088170 Otolemur garnettii 93.48 0.00e+00 892.00
IUUC-Oar-089388 Ovis aries 92.13 0.00e+00 880.00
IUUC-Ptr-090494 Pan troglodytes 93.48 0.00e+00 892.00
IUUC-Pan-091697 Papio anubis 94.16 0.00e+00 898.00
IUUC-Psi-093916 Pelodiscus sinensis 82.47 0.00e+00 773.00
IUUC-Pno-095004 Phaeosphaeria nodorum 41.74 2.00e-99 355.00
IUUC-Ppa-095514 Physcomitrella patens 47.12 5.00e-134 471.00
IUUC-Pfo-097432 Poecilia formosa 79.21 0.00e+00 740.00
IUUC-Pab-098423 Pongo abelii 94.16 0.00e+00 896.00
IUUC-Pop-099649 Populus trichocarpa 47.67 3.00e-132 464.00
IUUC-Pca-100365 Procavia capensis 88.31 0.00e+00 798.00
IUUC-Ppe-101379 Prunus persica 46.22 9.00e-129 453.00
IUUC-Pva-102845 Pteropus vampyrus 94.38 0.00e+00 888.00
IUUC-Pgr-103469 Puccinia graminis 34.12 1.00e-84 306.00
IUUC-Ptt-103980 Puccinia triticina 35.75 9.00e-65 241.00
IUUC-Pte-104111 Pyrenophora teres 44.35 2.00e-106 379.00
IUUC-Pyt-104610 Pyrenophora triticirepentis 44.44 2.00e-106 379.00
IUUC-Rno-105082 Rattus norvegicus 97.08 0.00e+00 920.00
IUUC-Sce-106340 Saccharomyces cerevisiae 46.25 5.00e-122 431.00
IUUC-Sha-106584 Sarcophilus harrisii 87.19 0.00e+00 842.00
IUUC-Sja-107703 Schizosaccharomyces japonicus 44.97 8.00e-105 374.00
IUUC-Spo-108046 Schizosaccharomyces pombe 46.65 6.00e-111 394.00
IUUC-Ssl-108574 Sclerotinia sclerotiorum 43.46 2.00e-107 382.00
IUUC-Smo-109548 Selaginella moellendorffii 47.32 3.00e-130 458.00
IUUC-Sit-110242 Setaria italica 47.79 5.00e-126 444.00
IUUC-Sly-111762 Solanum lycopersicum 46.90 5.00e-127 447.00
IUUC-Stu-112156 Solanum tuberosum 46.90 6.00e-127 447.00
IUUC-Sbi-114739 Sorghum bicolor 48.45 2.00e-127 449.00
IUUC-Sre-114951 Sporisorium reilianum 38.80 2.00e-102 365.00
IUUC-Ssc-115510 Sus scrofa 93.03 0.00e+00 889.00
IUUC-Tgu-117234 Taeniopygia guttata 88.15 0.00e+00 754.00
IUUC-Tru-117986 Takifugu rubripes 78.17 0.00e+00 766.00
IUUC-Tsy-119252 Tarsius syrichta 89.25 0.00e+00 809.00
IUUC-Tni-119785 Tetraodon nigroviridis 77.94 0.00e+00 721.00
IUUC-Tca-121222 Theobroma cacao 46.68 2.00e-127 449.00
IUUC-Tre-122243 Trichoderma reesei 43.85 8.00e-105 374.00
IUUC-Tvi-122293 Trichoderma virens 43.62 4.00e-103 368.00
IUUC-Tae-124591 Triticum aestivum 45.58 1.00e-112 400.00
IUUC-Tur-126098 Triticum urartu 44.52 2.00e-108 386.00
IUUC-Tme-127200 Tuber melanosporum 47.76 9.00e-127 447.00
IUUC-Tbe-127568 Tupaia belangeri 92.92 1.00e-130 459.00
IUUC-Ttr-129185 Tursiops truncatus 82.92 0.00e+00 770.00
IUUC-Uma-129353 Ustilago maydis 39.00 6.00e-102 364.00
IUUC-Vda-129768 Verticillium dahliae 43.36 3.00e-100 358.00
IUUC-Vpa-130572 Vicugna pacos 93.93 0.00e+00 898.00
IUUC-Vvi-131555 Vitis vinifera 47.12 2.00e-128 452.00
IUUC-Xtr-132263 Xenopus tropicalis 80.22 0.00e+00 641.00
IUUC-Xma-133925 Xiphophorus maculatus 79.67 0.00e+00 745.00
IUUC-Yli-134384 Yarrowia lipolytica 45.31 6.00e-115 407.00
IUUC-Zma-135616 Zea mays 48.23 2.00e-126 445.00
Created Date 25-Jun-2017

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