iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106822

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01038468

Gene Name

SOCS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000003825.1	ENSSHAT00000004389.1	ENSSHAP00000004345.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	2.50e-15	56.2	379	426

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 3    klwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +++l r+ p+SLqh+CR +I++c++++++   d+LP+P+s k YL++++y+
   Q: 379  STPLNRTFPFSLQHICRTVICNCTTYDGI---DTLPIPSSVKLYLKEYHYK 426
           5678899**********************...****************985 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

SEKMAENNIK NVDVRPKTSR SRSADRKDGY VWSGKKLSWS KKNEHSSDTD TPVATEKVDI 60
AVGSPERKHS CSSIDLDLDH SCGHRFLGRS LKQKLQDAVG QCFPIKNCSS RHSSVLPSKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTGAAAAAA TGGCAGAAAA TAATATTAAA AATGTAGATG TAAGACCCAA AACCAGTCGG 60
AGTAGAAGTG CAGACAGAAA AGATGGTTAT GTATGGAGTG GGAAAAAGCT CTCTTGGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028416--SOCS4
IPR022252--SOCS4/SOCS5_dom
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF12610--SOCS
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001789	Ailuropoda melanoleuca	83.37	0.00e+00	686.00
IUUC-Apl-003839	Anas platyrhynchos	77.68	4.00e-176	610.00
IUUC-Aca-004840	Anolis carolinensis	76.77	0.00e+00	664.00
IUUC-Bta-012503	Bos taurus	84.51	0.00e+00	693.00
IUUC-Bol-016597	Brassica oleracea	29.47	3.00e-02	33.50
IUUC-Cja-019284	Callithrix jacchus	84.28	0.00e+00	689.00
IUUC-Cfa-020890	Canis familiaris	83.37	0.00e+00	684.00
IUUC-Cpo-022081	Cavia porcellus	75.06	0.00e+00	637.00
IUUC-Csa-023076	Chlorocebus sabaeus	84.79	0.00e+00	693.00
IUUC-Cho-024700	Choloepus hoffmanni	83.91	0.00e+00	725.00
IUUC-Dno-029961	Dasypus novemcinctus	83.68	0.00e+00	717.00
IUUC-Dor-030273	Dipodomys ordii	83.91	0.00e+00	696.00
IUUC-Ete-032972	Echinops telfairi	83.60	3.00e-149	520.00
IUUC-Eca-034289	Equus caballus	83.68	0.00e+00	692.00
IUUC-Eeu-035208	Erinaceus europaeus	81.42	0.00e+00	673.00
IUUC-Fal-036829	Ficedula albicollis	77.68	5.00e-176	610.00
IUUC-Gga-040725	Gallus gallus	77.22	0.00e+00	631.00
IUUC-Ggo-044886	Gorilla gorilla	84.28	0.00e+00	694.00
IUUC-Hsa-046322	Homo sapiens	84.05	0.00e+00	692.00
IUUC-Itr-048585	Ictidomys tridecemlineatus	83.45	0.00e+00	694.00
IUUC-Lch-049459	Latimeria chalumnae	57.37	5.00e-131	460.00
IUUC-Laf-053484	Loxodonta africana	84.33	0.00e+00	690.00
IUUC-Mcc-054890	Macaca mulatta	84.56	0.00e+00	692.00
IUUC-Meu-056532	Macropus eugenii	92.35	0.00e+00	714.00
IUUC-Mtr-057670	Medicago truncatula	39.29	1.40e+00	26.90
IUUC-Mvi-060418	Microbotryum violaceum	32.10	4.80e-02	31.20
IUUC-Mmr-061714	Microcebus murinus	84.56	0.00e+00	691.00
IUUC-Mmu-063161	Mus musculus	80.05	0.00e+00	664.00
IUUC-Mpu-066499	Mustela putorius furo	83.18	0.00e+00	709.00
IUUC-Mlu-066945	Myotis lucifugus	82.69	0.00e+00	679.00
IUUC-Nle-069976	Nomascus leucogenys	84.05	0.00e+00	691.00
IUUC-Opr-070255	Ochotona princeps	81.61	0.00e+00	665.00
IUUC-Ocu-074764	Oryctolagus cuniculus	84.83	0.00e+00	692.00
IUUC-Oga-088910	Otolemur garnettii	79.77	0.00e+00	679.00
IUUC-Oar-090330	Ovis aries	84.51	0.00e+00	692.00
IUUC-Ptr-090709	Pan troglodytes	84.28	0.00e+00	694.00
IUUC-Pan-092540	Papio anubis	84.79	0.00e+00	693.00
IUUC-Psi-093678	Pelodiscus sinensis	79.27	0.00e+00	687.00
IUUC-Pab-097970	Pongo abelii	81.82	7.00e-162	563.00
IUUC-Pop-098820	Populus trichocarpa	41.18	1.30e-01	30.80
IUUC-Pca-100211	Procavia capensis	73.96	2.00e-165	575.00
IUUC-Rno-106014	Rattus norvegicus	79.08	0.00e+00	664.00
IUUC-Ssc-115821	Sus scrofa	84.83	0.00e+00	699.00
IUUC-Tgu-117117	Taeniopygia guttata	77.90	5.00e-176	610.00
IUUC-Tsy-118979	Tarsius syrichta	93.07	2.00e-119	421.00
IUUC-Tca-121131	Theobroma cacao	30.77	7.00e-03	34.70
IUUC-Vpa-130626	Vicugna pacos	84.02	0.00e+00	697.00
IUUC-Vvi-131327	Vitis vinifera	43.24	9.50e-02	31.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence