iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afu-008817

Ensembl Protein ID

CADAFUAP00003908

UniProt Accession

Q4X1Y0; PFS2_ASPFU

Genbank Protein ID

EAL93135.1

Protein Name

Polyadenylation factor subunit 2

Genbank Nucleotide ID

AAHF01000001

Gene Name

AFUA_2G08390; pfs2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADAFUAG00003908	CADAFUAT00003908	CADAFUAP00003908

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.10e-32	108.2	137	170
UBD/Beta-Prp	1.30e-43	148.3	25	318

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           +v ++++ ++ +llvsGs D+++k WD+rt ++l
   Q: 137  DVKSCDWhPTkGLLVSGSKDHQVKFWDPRTARCL 170
           5999****989********************997 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl......................lrsl.sgheaevtavkfspdgkilvtgseDrti 76
           g+ k++it+v ++p+++ l+tg+ +g   +w+ t  ++                      ++++   h ++v+++ +sp++  ++++s+D t+
   Q: 25   GKSKKPITVVRWTPEGRRLLTGGHTGEFMLWNGTAFNFetvmdvrgqkgdikywrpnfnnVETIdDAHHDAVRDLAWSPSDTKFLSASDDTTL 117
           67799******************************999**********************9999899************************** PP
   S: 77   kvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlkt 168
           k++d+ +++   +l+gh+ +v s++++p++  lvsGs+d  ++ wd +t  cl  tl  h+ +v++++++  + nll+++s D+t r++dl++
   Q: 118  KIFDFTARTADTVLTGHNWDVKSCDWHPTKGLLVSGSKDHQVKFWDPRTARCLT-TLHSHKNTVTTTRFSRVNsNLLATSSRDQTARVFDLRM 209
           *****************************************************9.************************************** PP
   S: 169  gkllrtltgghtdsvyslsfdsng.kelvsgsldgtvklwdlq.....tgec......................vrtlnghtdnvksvrfspn 233
           ++ +  l+g h++++ sl++++     + +gs+dg++  + l      +g++                       r++ +h+++++s++ +p 
   Q: 210  MRDICILRG-HEKPISSLTWHPIHsSLISTGSEDGSLYHYLLDepnlpSGQVptiapydspdpantpaqviypaHRIQYAHSATIWSLDWHPL 301
           ********9.***********987366678*************66666555599999999999999**999999999**************** PP
   S: 234  derlvsgssDgsiriWd 250
           +++l+sgs+D+  r+W 
   Q: 302  GHILASGSKDNFTRFWS 318
           ****************4 PP

Organism

Aspergillus fumigatus

Functional Description
(View)

Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle (By similarity).

Protein Sequence
(Fasta)

MLPPLARIHS PADTIPVRHL HQSIGKSKKP ITVVRWTPEG RRLLTGGHTG EFMLWNGTAF 60
NFETVMDVRG QKGDIKYWRP NFNNVETIDD AHHDAVRDLA WSPSDTKFLS ASDDTTLKIF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTTCCGC CGTTGGCGCG AATCCATTCT CCTGCAGATA CGATACCCGT ACGACACCTA 60
CACCAATCGA TCGGTAAATC GAAGAAACCT ATCACAGTTG TGAGATGGAC GCCAGAAGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0159--Chromosome partition
KW-0181--Complete proteome
KW-0507--mRNA processing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005847--C:mRNA cleavage and polyadenylation specificity factor complex
GO:0000790--C:nuclear chromatin
GO:0007059--P:chromosome segregation
GO:0031124--P:mRNA 3'-end processing

KEGG

afm:AFUA_2G08390

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001064	Aegilops tauschii	38.24	3.00e-74	271.00
IUUC-Aml-001363	Ailuropoda melanoleuca	41.01	4.00e-80	291.00
IUUC-Atr-003030	Amborella trichopoda	40.23	3.00e-79	288.00
IUUC-Apl-003409	Anas platyrhynchos	40.78	2.00e-78	285.00
IUUC-Aca-004694	Anolis carolinensis	41.01	8.00e-80	290.00
IUUC-Aly-006063	Arabidopsis lyrata	38.26	2.00e-81	295.00
IUUC-Ath-006583	Arabidopsis thaliana	39.35	1.00e-80	292.00
IUUC-Ago-007805	Ashbya gossypii	40.74	6.00e-74	269.00
IUUC-Acl-008075	Aspergillus clavatus	84.67	0.00e+00	841.00
IUUC-Afl-008582	Aspergillus flavus	81.30	0.00e+00	811.00
IUUC-Ani-009391	Aspergillus nidulans	91.37	0.00e+00	717.00
IUUC-Ang-009750	Aspergillus niger	88.43	2.00e-139	486.00
IUUC-Aor-010085	Aspergillus oryzae	81.48	0.00e+00	813.00
IUUC-Ate-010397	Aspergillus terreus	82.19	0.00e+00	803.00
IUUC-Ame-010741	Astyanax mexicanus	45.36	3.00e-46	178.00
IUUC-Bgr-012169	Blumeria graminis	64.80	3.00e-128	450.00
IUUC-Bta-013265	Bos taurus	41.01	8.00e-80	290.00
IUUC-Bci-013762	Botrytis cinerea	62.26	2.00e-146	510.00
IUUC-Bdi-014849	Brachypodium distachyon	40.00	2.00e-80	291.00
IUUC-Bol-015325	Brassica oleracea	38.74	5.00e-82	296.00
IUUC-Bra-017064	Brassica rapa	39.23	4.00e-83	300.00
IUUC-Cel-018378	Caenorhabditis elegans	40.77	1.00e-77	282.00
IUUC-Cja-019547	Callithrix jacchus	41.01	4.00e-80	291.00
IUUC-Cfa-020031	Canis familiaris	41.01	5.00e-80	291.00
IUUC-Cpo-021554	Cavia porcellus	41.01	1.00e-79	290.00
IUUC-Cre-022830	Chlamydomonas reinhardtii	34.67	2.00e-48	185.00
IUUC-Csa-023146	Chlorocebus sabaeus	40.73	1.00e-79	290.00
IUUC-Cho-024679	Choloepus hoffmanni	39.89	6.00e-76	278.00
IUUC-Cin-025415	Ciona intestinalis	38.48	2.00e-70	258.00
IUUC-Csv-026003	Ciona savignyi	38.48	6.00e-70	256.00
IUUC-Cgl-026391	Colletotrichum gloeosporioides	64.87	2.00e-144	503.00
IUUC-Cne-026983	Cryptococcus neoformans	40.67	1.00e-73	269.00
IUUC-Cme-027147	Cyanidioschyzon merolae	41.49	1.00e-76	278.00
IUUC-Dre-028545	Danio rerio	41.01	2.00e-80	292.00
IUUC-Dno-029677	Dasypus novemcinctus	41.01	3.00e-80	292.00
IUUC-Dse-031371	Dothistroma septosporum	54.72	4.00e-117	413.00
IUUC-Dme-031663	Drosophila melanogaster	40.45	2.00e-75	275.00
IUUC-Ete-032511	Echinops telfairi	32.87	6.00e-56	211.00
IUUC-Eca-034152	Equus caballus	41.01	5.00e-80	291.00
IUUC-Fca-035820	Felis catus	41.01	5.00e-80	291.00
IUUC-Fox-037958	Fusarium oxysporum	64.21	2.00e-142	497.00
IUUC-Fso-038162	Fusarium solani	63.93	7.00e-142	495.00
IUUC-Gmo-039708	Gadus morhua	40.83	5.00e-80	290.00
IUUC-Ggr-040031	Gaeumannomyces graminis	62.47	2.00e-135	473.00
IUUC-Gga-040963	Gallus gallus	41.01	5.00e-80	291.00
IUUC-Gac-041541	Gasterosteus aculeatus	40.17	4.00e-77	281.00
IUUC-Gma-044352	Glycine max	40.72	1.00e-82	298.00
IUUC-Ggo-045564	Gorilla gorilla	41.01	5.00e-80	291.00
IUUC-Hsa-045833	Homo sapiens	41.01	4.00e-80	291.00
IUUC-Hvu-047848	Hordeum vulgare	40.91	7.00e-62	229.00
IUUC-Itr-048083	Ictidomys tridecemlineatus	41.01	7.00e-80	290.00
IUUC-Kpa-049308	Komagataella pastoris	44.08	3.00e-89	320.00
IUUC-Lch-050525	Latimeria chalumnae	41.29	3.00e-80	292.00
IUUC-Lpe-051364	Leersia perrieri	34.65	2.00e-63	234.00
IUUC-Loc-052696	Lepisosteus oculatus	41.29	2.00e-80	292.00
IUUC-Lma-052951	Leptosphaeria maculans	60.71	7.00e-139	485.00
IUUC-Laf-053653	Loxodonta africana	41.01	2.00e-79	289.00
IUUC-Mcc-055797	Macaca mulatta	41.01	4.00e-80	291.00
IUUC-Meu-056331	Macropus eugenii	43.70	5.00e-66	244.00
IUUC-Mor-057168	Magnaporthe oryzae	56.57	1.00e-139	488.00
IUUC-Mpo-057510	Magnaporthe poae	57.21	2.00e-73	267.00
IUUC-Mtr-058032	Medicago truncatula	39.61	1.00e-79	289.00
IUUC-Mla-058852	Melampsora laricipopulina	42.74	2.00e-86	311.00
IUUC-Mga-059311	Meleagris gallopavo	41.01	6.00e-80	291.00
IUUC-Mvi-060544	Microbotryum violaceum	42.27	2.00e-84	305.00
IUUC-Mmr-061143	Microcebus murinus	41.01	5.00e-80	291.00
IUUC-Mdo-061977	Monodelphis domestica	41.01	7.00e-80	291.00
IUUC-Mmu-063922	Mus musculus	41.01	4.00e-80	291.00
IUUC-Mac-064961	Musa acuminata	39.72	2.00e-79	288.00
IUUC-Mpu-066079	Mustela putorius furo	41.26	4.00e-78	285.00
IUUC-Mlu-067247	Myotis lucifugus	41.01	3.00e-80	292.00
IUUC-Nfi-068255	Neosartorya fischeri	94.00	0.00e+00	870.00
IUUC-Ncr-068909	Neurospora crassa	65.32	2.00e-145	507.00
IUUC-Nle-068994	Nomascus leucogenys	41.01	4.00e-80	291.00
IUUC-Opr-071079	Ochotona princeps	41.01	3.00e-80	292.00
IUUC-Ont-071971	Oreochromis niloticus	41.01	1.00e-79	290.00
IUUC-Oan-073135	Ornithorhynchus anatinus	41.01	1.00e-79	290.00
IUUC-Ocu-073982	Oryctolagus cuniculus	41.01	6.00e-80	291.00
IUUC-Oba-075297	Oryza barthii	34.93	2.00e-65	241.00
IUUC-Obr-076641	Oryza brachyantha	37.23	8.00e-80	289.00
IUUC-Ogl-077539	Oryza glaberrima	40.14	2.00e-63	234.00
IUUC-Ogu-078807	Oryza glumaepatula	34.93	2.00e-65	241.00
IUUC-Oin-079229	Oryza indica	39.72	5.00e-80	290.00
IUUC-Olo-080371	Oryza longistaminata	34.93	3.00e-65	241.00
IUUC-Ome-081149	Oryza meridionalis	34.65	1.00e-64	239.00
IUUC-Oni-082970	Oryza nivara	34.93	2.00e-65	241.00
IUUC-Opu-083415	Oryza punctata	34.93	1.00e-63	236.00
IUUC-Oru-085236	Oryza rufipogon	34.93	2.00e-65	242.00
IUUC-Ola-087421	Oryzias latipes	35.22	1.00e-79	288.00
IUUC-Olu-087821	Ostreococcus lucimarinus	37.39	5.00e-71	259.00
IUUC-Oga-088132	Otolemur garnettii	41.01	4.00e-80	291.00
IUUC-Oar-089513	Ovis aries	41.01	8.00e-80	290.00
IUUC-Ptr-090717	Pan troglodytes	41.01	4.00e-80	291.00
IUUC-Pan-092108	Papio anubis	41.01	4.00e-80	291.00
IUUC-Psi-093892	Pelodiscus sinensis	41.01	2.00e-79	289.00
IUUC-Pma-094561	Petromyzon marinus	41.57	2.00e-79	289.00
IUUC-Pno-094943	Phaeosphaeria nodorum	58.93	1.00e-131	461.00
IUUC-Ppa-095359	Physcomitrella patens	43.90	5.00e-83	300.00
IUUC-Pfo-096516	Poecilia formosa	40.90	4.00e-78	284.00
IUUC-Pab-097759	Pongo abelii	41.01	5.00e-80	291.00
IUUC-Pop-099553	Populus trichocarpa	39.06	7.00e-82	296.00
IUUC-Ppe-101957	Prunus persica	38.57	3.00e-83	301.00
IUUC-Pva-102918	Pteropus vampyrus	41.01	7.00e-80	291.00
IUUC-Pgr-103594	Puccinia graminis	43.53	6.00e-88	317.00
IUUC-Ptt-103879	Puccinia triticina	43.50	1.00e-80	292.00
IUUC-Pte-104419	Pyrenophora teres	60.97	4.00e-139	486.00
IUUC-Pyt-104718	Pyrenophora triticirepentis	60.97	2.00e-139	487.00
IUUC-Rno-105838	Rattus norvegicus	41.01	3.00e-80	291.00
IUUC-Sce-106331	Saccharomyces cerevisiae	39.83	2.00e-70	258.00
IUUC-Sha-107435	Sarcophilus harrisii	41.01	6.00e-80	291.00
IUUC-Sja-107796	Schizosaccharomyces japonicus	48.35	7.00e-96	342.00
IUUC-Spo-108163	Schizosaccharomyces pombe	48.35	6.00e-99	352.00
IUUC-Smo-108972	Selaginella moellendorffii	43.75	1.00e-81	295.00
IUUC-Sit-109729	Setaria italica	39.15	3.00e-78	284.00
IUUC-Sly-111679	Solanum lycopersicum	38.50	8.00e-82	296.00
IUUC-Sar-113157	Sorex araneus	41.01	8.00e-80	290.00
IUUC-Sbi-114853	Sorghum bicolor	38.40	7.00e-78	283.00
IUUC-Sre-115085	Sporisorium reilianum	42.57	2.00e-76	278.00
IUUC-Ssc-116286	Sus scrofa	40.62	4.00e-78	285.00
IUUC-Tgu-117219	Taeniopygia guttata	41.01	8.00e-80	290.00
IUUC-Tru-117550	Takifugu rubripes	41.01	5.00e-80	290.00
IUUC-Tsy-119294	Tarsius syrichta	41.01	2.00e-80	292.00
IUUC-Tni-120561	Tetraodon nigroviridis	41.01	4.00e-80	291.00
IUUC-Tca-121347	Theobroma cacao	35.92	2.00e-81	295.00
IUUC-Tre-122018	Trichoderma reesei	62.64	1.00e-136	478.00
IUUC-Tvi-122413	Trichoderma virens	62.09	4.00e-135	473.00
IUUC-Tae-123191	Triticum aestivum	39.72	1.00e-79	289.00
IUUC-Tme-127077	Tuber melanosporum	54.15	2.00e-112	397.00
IUUC-Tbe-127744	Tupaia belangeri	28.83	2.00e-35	143.00
IUUC-Ttr-128777	Tursiops truncatus	32.87	2.00e-55	209.00
IUUC-Uma-129568	Ustilago maydis	42.15	1.00e-75	275.00
IUUC-Vda-129834	Verticillium dahliae	61.54	6.00e-137	479.00
IUUC-Vvi-131360	Vitis vinifera	41.01	1.00e-81	296.00
IUUC-Xtr-132630	Xenopus tropicalis	41.57	2.00e-80	292.00
IUUC-Xma-133665	Xiphophorus maculatus	41.29	8.00e-80	290.00
IUUC-Yli-134556	Yarrowia lipolytica	40.22	1.00e-77	281.00
IUUC-Zma-135787	Zea mays	38.87	6.00e-79	286.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence