iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-055093

UUCD1 version

UUC-MaM-00935

Ensembl Protein ID

ENSMMUP00000010980.3

UniProt Accession

F7HMP1; I0FKH5; F7HMP1_MACMU

Genbank Protein ID

AFI34951.1

Protein Name

E3 ubiquitin-protein ligase RFWD3

Genbank Nucleotide ID

JSUE03026615

Gene Name

RFWD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000008375.3	ENSMMUT00000011709.3	ENSMMUP00000010980.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-08	35.7	496	534

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlrtgvllk 37
           H   +++laf   s +ll+s+s D+tik+ +l t+++++
   Q: 496  HGKQIRGLAFssySRGLLLSASLDNTIKLTSLETNTVVQ 534
           8889******975339************98888877766 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAHEAMEYDL QVQLNHAEEQ PASADVASSQ GGPALLQPVP ADVVSSQGGP LIFQPAPAEV 60
IGSQVTPPLL QPTPQLSIDL TEVEVLGEDN VENINPRTSE QHRQASDANH TMRASSLHSM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGATGGCTCA TGAAGCAATG GAATATGATC TTCAGGTACA GTTAAATCAT GCTGAAGAAC 60
AGCCAGCTTC TGCTGATGTG GCCAGCAGCC AAGGGGGACC AGCCCTCCTC CAGCCTGTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0035861--C:site of double-strand break
GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0031571--P:mitotic G1 DNA damage checkpoint
GO:2000001--P:regulation of DNA damage checkpoint
GO:0010212--P:response to ionizing radiation

KEGG

mcc:710227

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000929	Aegilops tauschii	23.03	7.00e-16	79.00
IUUC-Aml-001188	Ailuropoda melanoleuca	78.08	0.00e+00	1132.00
IUUC-Atr-003034	Amborella trichopoda	26.50	5.00e-17	81.60
IUUC-Apl-003182	Anas platyrhynchos	61.41	0.00e+00	714.00
IUUC-Aca-004619	Anolis carolinensis	69.03	0.00e+00	733.00
IUUC-Aly-006391	Arabidopsis lyrata	26.82	2.00e-31	130.00
IUUC-Ath-007300	Arabidopsis thaliana	26.11	2.00e-30	127.00
IUUC-Ame-010890	Astyanax mexicanus	59.31	0.00e+00	629.00
IUUC-Bta-013051	Bos taurus	72.77	0.00e+00	1046.00
IUUC-Bdi-014519	Brachypodium distachyon	27.10	1.00e-21	97.80
IUUC-Bol-015271	Brassica oleracea	29.50	7.00e-30	125.00
IUUC-Bra-017931	Brassica rapa	31.19	5.00e-30	125.00
IUUC-Cja-019240	Callithrix jacchus	88.00	0.00e+00	1275.00
IUUC-Cfa-021010	Canis familiaris	76.45	0.00e+00	1125.00
IUUC-Cpo-022308	Cavia porcellus	72.86	0.00e+00	964.00
IUUC-Csa-023501	Chlorocebus sabaeus	98.19	0.00e+00	1509.00
IUUC-Cho-024900	Choloepus hoffmanni	69.88	0.00e+00	999.00
IUUC-Cin-025403	Ciona intestinalis	36.80	1.00e-93	337.00
IUUC-Csv-025819	Ciona savignyi	37.50	1.00e-43	169.00
IUUC-Cme-027123	Cyanidioschyzon merolae	25.76	5.00e-19	89.40
IUUC-Dre-028354	Danio rerio	56.82	8.00e-166	577.00
IUUC-Dno-029400	Dasypus novemcinctus	73.16	0.00e+00	1057.00
IUUC-Dor-030320	Dipodomys ordii	73.04	0.00e+00	841.00
IUUC-Dme-031949	Drosophila melanogaster	27.32	6.00e-46	178.00
IUUC-Ete-032691	Echinops telfairi	57.33	1.00e-142	500.00
IUUC-Eca-034320	Equus caballus	80.05	0.00e+00	1223.00
IUUC-Fca-035732	Felis catus	77.11	0.00e+00	1077.00
IUUC-Fal-036648	Ficedula albicollis	69.90	0.00e+00	728.00
IUUC-Gmo-038609	Gadus morhua	56.19	1.00e-139	489.00
IUUC-Gga-040522	Gallus gallus	69.62	1.00e-106	380.00
IUUC-Gac-042318	Gasterosteus aculeatus	54.81	5.00e-133	467.00
IUUC-Gma-043184	Glycine max	27.09	9.00e-26	112.00
IUUC-Ggo-044464	Gorilla gorilla	95.61	0.00e+00	1447.00
IUUC-Hsa-045991	Homo sapiens	95.35	0.00e+00	1438.00
IUUC-Hvu-047705	Hordeum vulgare	24.22	1.00e-27	117.00
IUUC-Itr-047977	Ictidomys tridecemlineatus	79.38	0.00e+00	1157.00
IUUC-Lch-050112	Latimeria chalumnae	64.08	0.00e+00	669.00
IUUC-Lpe-051605	Leersia perrieri	27.59	8.00e-19	89.00
IUUC-Loc-052241	Lepisosteus oculatus	63.69	0.00e+00	647.00
IUUC-Laf-054559	Loxodonta africana	74.26	0.00e+00	950.00
IUUC-Meu-056417	Macropus eugenii	66.21	0.00e+00	688.00
IUUC-Mtr-058533	Medicago truncatula	25.30	8.00e-32	132.00
IUUC-Mga-059498	Meleagris gallopavo	60.29	0.00e+00	709.00
IUUC-Mmr-061782	Microcebus murinus	76.43	0.00e+00	1130.00
IUUC-Mdo-062053	Monodelphis domestica	71.92	0.00e+00	757.00
IUUC-Mmu-063352	Mus musculus	66.58	0.00e+00	991.00
IUUC-Mac-064582	Musa acuminata	26.76	2.00e-22	100.00
IUUC-Mpu-066087	Mustela putorius furo	76.22	0.00e+00	1131.00
IUUC-Mlu-068147	Myotis lucifugus	74.87	0.00e+00	1036.00
IUUC-Nle-069503	Nomascus leucogenys	92.12	0.00e+00	1375.00
IUUC-Opr-070479	Ochotona princeps	67.40	0.00e+00	980.00
IUUC-Ont-071700	Oreochromis niloticus	58.33	6.00e-172	597.00
IUUC-Oan-073702	Ornithorhynchus anatinus	73.99	0.00e+00	780.00
IUUC-Ocu-074886	Oryctolagus cuniculus	74.78	0.00e+00	1114.00
IUUC-Oba-075729	Oryza barthii	29.10	1.00e-24	108.00
IUUC-Obr-076562	Oryza brachyantha	27.27	1.00e-22	101.00
IUUC-Ogl-077615	Oryza glaberrima	29.10	1.00e-24	108.00
IUUC-Ogu-078921	Oryza glumaepatula	29.10	2.00e-25	110.00
IUUC-Oin-079250	Oryza indica	26.77	7.00e-19	88.60
IUUC-Olo-080758	Oryza longistaminata	24.20	8.00e-24	105.00
IUUC-Ome-081707	Oryza meridionalis	27.42	1.00e-20	94.70
IUUC-Oni-083006	Oryza nivara	25.41	4.00e-25	109.00
IUUC-Opu-083650	Oryza punctata	28.57	3.00e-25	109.00
IUUC-Oru-084924	Oryza rufipogon	28.93	1.00e-25	111.00
IUUC-Osa-085820	Oryza sativa	29.10	4.00e-25	109.00
IUUC-Ola-087229	Oryzias latipes	56.90	2.00e-137	482.00
IUUC-Oga-088243	Otolemur garnettii	72.63	0.00e+00	1039.00
IUUC-Oar-089461	Ovis aries	74.90	0.00e+00	1130.00
IUUC-Ptr-090527	Pan troglodytes	95.74	0.00e+00	1438.00
IUUC-Pan-092431	Papio anubis	99.17	0.00e+00	1427.00
IUUC-Psi-093156	Pelodiscus sinensis	53.88	0.00e+00	764.00
IUUC-Pno-094897	Phaeosphaeria nodorum	24.58	3.00e-08	52.40
IUUC-Ppa-095305	Physcomitrella patens	43.09	7.00e-21	96.30
IUUC-Pfo-097065	Poecilia formosa	57.09	3.00e-164	572.00
IUUC-Pab-098272	Pongo abelii	95.99	0.00e+00	1474.00
IUUC-Pop-099827	Populus trichocarpa	32.25	4.00e-35	142.00
IUUC-Pca-100713	Procavia capensis	63.19	0.00e+00	910.00
IUUC-Ppe-102103	Prunus persica	25.75	1.00e-33	137.00
IUUC-Pva-103133	Pteropus vampyrus	83.13	0.00e+00	728.00
IUUC-Ptt-103972	Puccinia triticina	32.89	2.00e-05	43.90
IUUC-Sha-107628	Sarcophilus harrisii	56.98	0.00e+00	806.00
IUUC-Sit-109891	Setaria italica	24.67	1.00e-26	114.00
IUUC-Sly-111779	Solanum lycopersicum	31.41	3.00e-32	133.00
IUUC-Stu-112817	Solanum tuberosum	42.61	8.00e-19	87.40
IUUC-Sar-113124	Sorex araneus	63.71	0.00e+00	681.00
IUUC-Sbi-114107	Sorghum bicolor	25.63	6.00e-29	122.00
IUUC-Sre-115057	Sporisorium reilianum	33.33	4.00e-06	46.60
IUUC-Ssc-115850	Sus scrofa	76.43	0.00e+00	1110.00
IUUC-Tgu-117295	Taeniopygia guttata	69.74	0.00e+00	739.00
IUUC-Tru-117539	Takifugu rubripes	55.11	5.00e-168	584.00
IUUC-Tsy-118805	Tarsius syrichta	70.95	1.00e-111	397.00
IUUC-Tni-120274	Tetraodon nigroviridis	57.49	9.00e-168	583.00
IUUC-Tca-121162	Theobroma cacao	30.25	2.00e-31	130.00
IUUC-Tae-124822	Triticum aestivum	24.95	8.00e-29	122.00
IUUC-Tur-126162	Triticum urartu	26.33	1.00e-16	82.00
IUUC-Tbe-127884	Tupaia belangeri	72.69	5.00e-84	305.00
IUUC-Ttr-128665	Tursiops truncatus	71.70	0.00e+00	989.00
IUUC-Uma-129349	Ustilago maydis	33.33	2.00e-06	47.80
IUUC-Vpa-130385	Vicugna pacos	79.92	0.00e+00	1134.00
IUUC-Vvi-131464	Vitis vinifera	29.72	2.00e-25	110.00
IUUC-Xtr-132015	Xenopus tropicalis	60.23	0.00e+00	707.00
IUUC-Xma-133109	Xiphophorus maculatus	57.31	1.00e-164	573.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence