iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nfi-068278

Ensembl Protein ID

CADNFIAP00009491

UniProt Accession

A1CWP1; A1CWP1_NEOFI

Genbank Protein ID

EAW25043.1

Protein Name

Ubiquitin-protein ligase (Tom1), putative

Genbank Nucleotide ID

DS027685

Gene Name

NFIA_105310

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADNFIAG00009731	CADNFIAT00009731	CADNFIAP00009491

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	6.00e-119	396.4	3707	4038

Active Site

Position(s)	Description	Evidence
4007	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkk.rlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlpls 93
           +lk+ +l+v+f gEeg+d+gGvtre+++ l++ ++np++ lf   + d++t++pn+ sg+ n ehl +F+f+Gr++gkal++gr+ld+++s
   Q: 3707 ELKYgKLNVRFHGEEGVDAGGVTREWFQVLARGMFNPNYALFIPVAADRTTFHPNRLSGV-NSEHLMFFKFIGRIIGKALYEGRVLDCHFS 3796
           66755899***************************************************9.56**************************** PP
   S: 94   ksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlke 184
           +++yk++lg+++s++d+e++d ++yksl +++en   di+++ ++ tf v+++ +ge ++ +L+++G+nipVt+eNkeeYv++vv+yrl +
   Q: 3797 RAVYKCILGRSVSIKDMETLDLDYYKSLLWMLEN---DITDI-ITETFAVETDDFGEKQVIDLIENGRNIPVTQENKEEYVQRVVDYRLVK 3883
           ********************************99...99999.999********************************************* PP
   S: 185  gikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlP 275
           ++k q+++f +Gf+e+ip++l+s+F+e+elelli+G +eidv+d+k++t+y++ y+++sp+iqwFw+++++f++eer+++LqFvTg+s++P
   Q: 3884 SVKDQLDNFLKGFHEIIPPDLISIFNEQELELLISGLPEIDVDDWKANTEYHN-YSASSPQIQWFWRAVRSFDKEERAKLLQFVTGTSKVP 3973
           ***************************************************66.************************************* PP
   S: 276  lgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFe 334
           l+Gf+el+     ++f i++ ++++drlPss+TCfn+L+LPeY+s+e+l+++L +A++ + + F+
   Q: 3974 LNGFKELEgmngVSKFNIHRdYGNKDRLPSSHTCFNQLDLPEYDSYETLRQRLYTAMTAGsDYFG 4038
           ********99997778888878889*******************************998866665 PP

Organism

Neosartorya fischeri

Protein Sequence
(Fasta)

MGRIKKVASQ KHEATISPYL TEFVARATTI SVPELPLHLN TFSRLWPFPR GDLYHWINVL 60
NRFDDILASV IEKYALNAGP QTKPFGRYVL IDAYTSSDGQ SSSEDADSKL NALGYGPEGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGAGAA TTAAGAAGGT GGCCAGCCAA AAGCATGAGG CGACAATTGT AAGTTCATTC 60
ACCCCGCTCG ATCTCCAGCT CTGGAATGCA GGCTGACTGA AAATTTTCTT TCCTGTTTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

nfi:NFIA_105310

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	31.87	4.00e-125	442.00
IUUC-Aml-001684	Ailuropoda melanoleuca	53.43	2.00e-133	470.00
IUUC-Atr-003044	Amborella trichopoda	42.30	5.00e-139	489.00
IUUC-Apl-003729	Anas platyrhynchos	52.11	7.00e-101	358.00
IUUC-Aca-005263	Anolis carolinensis	53.90	8.00e-135	475.00
IUUC-Aly-006157	Arabidopsis lyrata	41.49	2.00e-139	490.00
IUUC-Ath-007472	Arabidopsis thaliana	43.61	3.00e-136	479.00
IUUC-Ago-008005	Ashbya gossypii	57.70	0.00e+00	753.00
IUUC-Acl-008254	Aspergillus clavatus	84.36	0.00e+00	3960.00
IUUC-Afl-008712	Aspergillus flavus	86.33	0.00e+00	1858.00
IUUC-Afu-009022	Aspergillus fumigatus	97.45	0.00e+00	7237.00
IUUC-Ani-009412	Aspergillus nidulans	71.34	0.00e+00	3729.00
IUUC-Ang-009771	Aspergillus niger	79.83	0.00e+00	5995.00
IUUC-Aor-010186	Aspergillus oryzae	83.75	0.00e+00	2151.00
IUUC-Ate-010253	Aspergillus terreus	74.80	0.00e+00	3460.00
IUUC-Ame-011067	Astyanax mexicanus	53.18	9.00e-133	468.00
IUUC-Bgr-012043	Blumeria graminis	39.94	0.00e+00	1512.00
IUUC-Bta-012813	Bos taurus	53.43	1.00e-133	471.00
IUUC-Bci-013995	Botrytis cinerea	59.79	0.00e+00	1239.00
IUUC-Bdi-014884	Brachypodium distachyon	34.65	2.00e-137	483.00
IUUC-Bol-016533	Brassica oleracea	56.00	1.00e-92	330.00
IUUC-Bra-016726	Brassica rapa	43.22	1.00e-139	491.00
IUUC-Cel-018179	Caenorhabditis elegans	51.76	6.00e-130	459.00
IUUC-Cja-018741	Callithrix jacchus	53.43	6.00e-133	468.00
IUUC-Cfa-020083	Canis familiaris	53.43	2.00e-133	470.00
IUUC-Cpo-021766	Cavia porcellus	42.66	4.00e-97	347.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	52.25	1.00e-132	464.00
IUUC-Csa-023853	Chlorocebus sabaeus	53.43	1.00e-133	471.00
IUUC-Cho-024718	Choloepus hoffmanni	55.99	6.00e-122	432.00
IUUC-Cin-025627	Ciona intestinalis	52.48	7.00e-132	465.00
IUUC-Csv-025872	Ciona savignyi	52.25	2.00e-128	450.00
IUUC-Cgl-026647	Colletotrichum gloeosporioides	35.84	0.00e+00	1229.00
IUUC-Cne-027095	Cryptococcus neoformans	41.61	0.00e+00	643.00
IUUC-Cme-027267	Cyanidioschyzon merolae	51.31	5.00e-120	424.00
IUUC-Dre-028525	Danio rerio	52.70	3.00e-121	430.00
IUUC-Dno-029680	Dasypus novemcinctus	53.43	2.00e-133	471.00
IUUC-Dor-030902	Dipodomys ordii	48.23	5.00e-113	402.00
IUUC-Dse-031197	Dothistroma septosporum	36.55	0.00e+00	1322.00
IUUC-Dme-032122	Drosophila melanogaster	52.71	1.00e-129	458.00
IUUC-Ete-032966	Echinops telfairi	42.66	3.00e-97	347.00
IUUC-Eca-033915	Equus caballus	52.37	4.00e-131	462.00
IUUC-Eeu-034963	Erinaceus europaeus	53.07	2.00e-131	464.00
IUUC-Fca-035824	Felis catus	53.43	2.00e-133	471.00
IUUC-Fox-037756	Fusarium oxysporum	57.43	0.00e+00	1257.00
IUUC-Fso-038464	Fusarium solani	57.39	0.00e+00	1242.00
IUUC-Gmo-039073	Gadus morhua	53.19	9.00e-134	471.00
IUUC-Ggr-039946	Gaeumannomyces graminis	58.36	0.00e+00	1211.00
IUUC-Gga-040309	Gallus gallus	57.98	8.00e-106	374.00
IUUC-Gac-042430	Gasterosteus aculeatus	53.19	1.00e-133	471.00
IUUC-Gma-044216	Glycine max	33.53	3.00e-157	549.00
IUUC-Hsa-046879	Homo sapiens	53.43	2.00e-133	470.00
IUUC-Hvu-047697	Hordeum vulgare	33.25	6.00e-148	518.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	53.43	4.00e-134	471.00
IUUC-Kpa-049228	Komagataella pastoris	59.87	0.00e+00	777.00
IUUC-Lch-050252	Latimeria chalumnae	53.30	8.00e-133	468.00
IUUC-Lpe-051550	Leersia perrieri	40.58	7.00e-137	481.00
IUUC-Loc-052472	Lepisosteus oculatus	53.66	1.00e-134	474.00
IUUC-Lma-053159	Leptosphaeria maculans	41.62	0.00e+00	1645.00
IUUC-Laf-054154	Loxodonta africana	53.43	1.00e-133	471.00
IUUC-Mcc-055085	Macaca mulatta	53.43	1.00e-133	471.00
IUUC-Mor-057201	Magnaporthe oryzae	56.33	0.00e+00	1186.00
IUUC-Mpo-057597	Magnaporthe poae	71.05	0.00e+00	961.00
IUUC-Mtr-057633	Medicago truncatula	32.91	3.00e-158	552.00
IUUC-Mla-058888	Melampsora laricipopulina	59.21	6.00e-146	508.00
IUUC-Mga-059935	Meleagris gallopavo	42.66	1.00e-96	346.00
IUUC-Mvi-060320	Microbotryum violaceum	44.62	0.00e+00	753.00
IUUC-Mmr-060820	Microcebus murinus	53.43	1.00e-133	471.00
IUUC-Mdo-062930	Monodelphis domestica	53.66	4.00e-134	473.00
IUUC-Mmu-063601	Mus musculus	53.43	1.00e-133	471.00
IUUC-Mac-065229	Musa acuminata	33.59	1.00e-157	550.00
IUUC-Mpu-066653	Mustela putorius furo	53.43	2.00e-133	470.00
IUUC-Mlu-067418	Myotis lucifugus	53.43	1.00e-133	471.00
IUUC-Ncr-068813	Neurospora crassa	35.09	0.00e+00	1165.00
IUUC-Nle-069418	Nomascus leucogenys	53.43	2.00e-133	470.00
IUUC-Ont-071300	Oreochromis niloticus	53.19	1.00e-133	471.00
IUUC-Oan-073046	Ornithorhynchus anatinus	53.65	2.00e-133	471.00
IUUC-Ocu-074178	Oryctolagus cuniculus	53.43	9.00e-134	471.00
IUUC-Oba-075757	Oryza barthii	32.80	9.00e-150	524.00
IUUC-Obr-076553	Oryza brachyantha	41.98	3.00e-139	489.00
IUUC-Ogl-077520	Oryza glaberrima	32.80	2.00e-149	523.00
IUUC-Ogu-078278	Oryza glumaepatula	40.23	1.00e-139	491.00
IUUC-Oin-079767	Oryza indica	33.04	8.00e-150	524.00
IUUC-Olo-080380	Oryza longistaminata	32.98	2.00e-145	510.00
IUUC-Ome-081925	Oryza meridionalis	32.69	2.00e-147	516.00
IUUC-Oni-082619	Oryza nivara	32.80	1.00e-149	524.00
IUUC-Opu-083684	Oryza punctata	33.09	6.00e-146	511.00
IUUC-Oru-084501	Oryza rufipogon	33.04	5.00e-150	525.00
IUUC-Osa-086251	Oryza sativa	40.23	3.00e-139	487.00
IUUC-Ola-086777	Oryzias latipes	42.89	2.00e-98	352.00
IUUC-Olu-087813	Ostreococcus lucimarinus	47.91	2.00e-115	407.00
IUUC-Oga-088903	Otolemur garnettii	53.43	1.00e-133	471.00
IUUC-Oar-090210	Ovis aries	53.43	1.00e-133	471.00
IUUC-Ptr-090529	Pan troglodytes	42.66	9.00e-97	346.00
IUUC-Pan-092368	Papio anubis	53.21	2.00e-121	431.00
IUUC-Pno-094871	Phaeosphaeria nodorum	41.40	0.00e+00	1627.00
IUUC-Ppa-095657	Physcomitrella patens	46.02	4.00e-131	462.00
IUUC-Pfo-096232	Poecilia formosa	53.19	8.00e-134	471.00
IUUC-Pab-098583	Pongo abelii	53.43	2.00e-133	470.00
IUUC-Pop-099613	Populus trichocarpa	40.56	5.00e-139	488.00
IUUC-Ppe-101641	Prunus persica	45.69	7.00e-138	485.00
IUUC-Pva-102116	Pteropus vampyrus	50.35	5.00e-120	426.00
IUUC-Pgr-103465	Puccinia graminis	49.33	0.00e+00	643.00
IUUC-Ptt-103813	Puccinia triticina	42.00	0.00e+00	762.00
IUUC-Pte-104018	Pyrenophora teres	42.37	0.00e+00	1730.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	42.03	0.00e+00	1689.00
IUUC-Rno-105153	Rattus norvegicus	42.66	4.00e-97	347.00
IUUC-Sce-106449	Saccharomyces cerevisiae	55.85	0.00e+00	731.00
IUUC-Sha-106961	Sarcophilus harrisii	46.27	3.00e-134	473.00
IUUC-Sja-107814	Schizosaccharomyces japonicus	46.01	0.00e+00	912.00
IUUC-Spo-108024	Schizosaccharomyces pombe	46.80	0.00e+00	844.00
IUUC-Smo-109640	Selaginella moellendorffii	51.03	4.00e-135	475.00
IUUC-Sit-110598	Setaria italica	35.44	3.00e-140	493.00
IUUC-Sly-111706	Solanum lycopersicum	41.82	3.00e-140	493.00
IUUC-Stu-112894	Solanum tuberosum	34.44	2.00e-56	212.00
IUUC-Sar-113291	Sorex araneus	53.37	6.00e-129	456.00
IUUC-Sbi-114042	Sorghum bicolor	33.64	1.00e-148	520.00
IUUC-Sre-114958	Sporisorium reilianum	58.94	2.00e-175	606.00
IUUC-Ssc-115754	Sus scrofa	53.43	2.00e-133	470.00
IUUC-Tru-118570	Takifugu rubripes	53.19	9.00e-134	471.00
IUUC-Tni-120836	Tetraodon nigroviridis	51.54	8.00e-128	451.00
IUUC-Tca-121479	Theobroma cacao	33.63	3.00e-152	533.00
IUUC-Tre-121909	Trichoderma reesei	58.29	0.00e+00	1205.00
IUUC-Tvi-122370	Trichoderma virens	57.54	0.00e+00	1211.00
IUUC-Tae-125214	Triticum aestivum	32.17	7.00e-144	504.00
IUUC-Tur-126774	Triticum urartu	32.20	4.00e-51	194.00
IUUC-Tme-127172	Tuber melanosporum	73.62	0.00e+00	992.00
IUUC-Ttr-129253	Tursiops truncatus	53.43	2.00e-133	470.00
IUUC-Uma-129355	Ustilago maydis	57.94	1.00e-179	621.00
IUUC-Vda-129886	Verticillium dahliae	57.78	0.00e+00	1200.00
IUUC-Vpa-130708	Vicugna pacos	53.43	4.00e-133	469.00
IUUC-Vvi-131078	Vitis vinifera	44.09	2.00e-138	486.00
IUUC-Xtr-132123	Xenopus tropicalis	52.10	3.00e-127	450.00
IUUC-Xma-133869	Xiphophorus maculatus	53.19	8.00e-134	471.00
IUUC-Yli-134657	Yarrowia lipolytica	48.23	0.00e+00	978.00
IUUC-Zma-135570	Zea mays	43.41	1.00e-139	490.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence