iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afu-008812

Ensembl Protein ID

CADAFUAP00001717

UniProt Accession

Q4WMS5; Q4WMS5_ASPFU

Genbank Protein ID

EAL88739.2

Protein Name

Ubiquitin-protein ligase Ufd4, putative

Genbank Nucleotide ID

AAHF01000006

Gene Name

AFUA_6G08880

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADAFUAG00001717	CADAFUAT00001717	CADAFUAP00001717

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.10e-81	273.8	1445	1817

Active Site

Position(s)	Description	Evidence
1784	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 6    kkrlevefvgEegldlgGvtreflallskelqnpdlglflysen.dketlqpnpdsglknp............ehlklFeflGrllgkalq 83
            ++leve+ +E g++l G+t+ef++ +ske+ +++l++++ ++  ++e++   +   +  p            ++l+lF+ lG++++ ++ 
   Q: 1445 PSVLEVEYFEEVGTGL-GPTLEFYSTVSKEFSKKKLKIWRENDChNDEEFAFGKRGLFPAPmseeqansesgkKQLSLFKTLGKFVARSML 1534
           5789************.**********************4444334444444444444334555556699999****************** PP
   S: 84   dgrlldlplsksfyklllgk...klsledleevdpelykslkeikenaes.........................dieelgldltfsvsee 146
           d+r++d+ ++++f++   +      sl  +++vd++l++sl+ +k+ a++                          +  ++l l f+    
   Q: 1535 DSRIIDISFNPAFFRIADSSssvAPSLGTVKAVDQDLANSLMLLKRFANAkraidrdrtlsaaaksqalqnveidGVRVEDLSLDFT---- 1621
           **************977444444799*******************998445566666666667776777766666444444555554.... PP
   S: 147  ilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkyk 236
            l+ + + eL+ +G+n+pVt+eN + Yv++vv+++l +g+++qveafr Gf++v+p + l+ Ft++el +l     e++++e+l + +k +
   Q: 1622 -LPGYPSIELIDNGSNVPVTIENVDTYVDRVVDMTLGSGVQRQVEAFRTGFSQVFPYSALRTFTPNELVMLFGRAeEDWTIETLMDSIKAD 1711
           .89*****************************************************************988777689************** PP
   S: 237  ggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk.....dasddrlPssnTCfnyLkLPeYsskeilkek 322
           +g++ ds+ +++++++++e++ ++r++fLqFvTgs++lP+gGf++l p ++v+ +     ++ dd lPs++TC+nyLkLP+Yss e+l+e+
   Q: 1712 HGFNMDSKSVRNLLQTMSELDTQQRRDFLQFVTGSPKLPIGGFKSLTPTFTVVCRpseppYTPDDYLPSVMTCVNYLKLPDYSSLEVLRER 1802
           **************************************************99998999*99999*************************** PP
   S: 323  LlyAieet.kgFels 336
           L +Ai+e+  +F+ls
   Q: 1803 LSVAIREGqGAFHLS 1817
           ********8899985 PP

Organism

Aspergillus fumigatus

Protein Sequence
(Fasta)

MSPRITRSAA RLAADSPSSA GSGPSSIPAA GSAPTRKRKA HARRDPPLDV PEETNPQSPT 60
RRTKRQRLAS PPHPASTVST SRRGTRNRPA MSQQGPSASS PEETTKKQSS PPPSRRKSSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCCCCA GAATCACTCG CTCAGCTGCG AGACTTGCTG CAGACTCCCC CTCGTCCGCT 60
GGCTCCGGCC CCTCCTCGAT TCCAGCCGCT GGTTCGGCCC CAACTCGAAA ACGCAAGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

afm:AFUA_6G08880

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000750	Aegilops tauschii	40.77	2.00e-113	402.00
IUUC-Aml-001502	Ailuropoda melanoleuca	36.13	3.00e-116	412.00
IUUC-Atr-002821	Amborella trichopoda	38.56	4.00e-110	391.00
IUUC-Apl-003531	Anas platyrhynchos	33.89	6.00e-107	381.00
IUUC-Aca-004521	Anolis carolinensis	34.23	2.00e-36	147.00
IUUC-Aly-005962	Arabidopsis lyrata	41.55	4.00e-115	408.00
IUUC-Ath-006636	Arabidopsis thaliana	41.48	7.00e-117	414.00
IUUC-Ago-007875	Ashbya gossypii	43.16	1.00e-128	453.00
IUUC-Acl-008242	Aspergillus clavatus	83.83	0.00e+00	2786.00
IUUC-Afl-008736	Aspergillus flavus	78.86	0.00e+00	2525.00
IUUC-Ani-009407	Aspergillus nidulans	74.44	0.00e+00	2368.00
IUUC-Ang-009763	Aspergillus niger	76.36	0.00e+00	2323.00
IUUC-Aor-009941	Aspergillus oryzae	78.39	0.00e+00	1268.00
IUUC-Ate-010459	Aspergillus terreus	75.76	0.00e+00	2387.00
IUUC-Ame-011761	Astyanax mexicanus	37.33	8.00e-123	434.00
IUUC-Bgr-012265	Blumeria graminis	54.66	0.00e+00	1781.00
IUUC-Bta-013070	Bos taurus	35.70	2.00e-116	412.00
IUUC-Bci-013890	Botrytis cinerea	60.40	0.00e+00	1773.00
IUUC-Bdi-014046	Brachypodium distachyon	36.27	4.00e-113	401.00
IUUC-Bol-015942	Brassica oleracea	40.89	3.00e-112	399.00
IUUC-Bra-016849	Brassica rapa	40.89	4.00e-112	398.00
IUUC-Cel-018153	Caenorhabditis elegans	34.01	4.00e-82	299.00
IUUC-Cja-019046	Callithrix jacchus	35.55	7.00e-116	411.00
IUUC-Cfa-020521	Canis familiaris	35.40	6.00e-116	411.00
IUUC-Cpo-021639	Cavia porcellus	35.55	1.00e-115	410.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	39.16	4.00e-90	323.00
IUUC-Csa-023231	Chlorocebus sabaeus	35.55	7.00e-116	411.00
IUUC-Cho-024380	Choloepus hoffmanni	41.34	2.00e-92	333.00
IUUC-Cin-025482	Ciona intestinalis	37.24	5.00e-101	359.00
IUUC-Csv-026121	Ciona savignyi	34.22	2.00e-100	359.00
IUUC-Cgl-026716	Colletotrichum gloeosporioides	65.11	0.00e+00	910.00
IUUC-Cne-026857	Cryptococcus neoformans	45.15	3.00e-155	541.00
IUUC-Cme-027226	Cyanidioschyzon merolae	36.88	1.00e-80	293.00
IUUC-Dre-028174	Danio rerio	37.63	4.00e-123	435.00
IUUC-Dno-029954	Dasypus novemcinctus	33.85	3.00e-36	147.00
IUUC-Dor-030939	Dipodomys ordii	31.47	9.00e-94	337.00
IUUC-Dse-031444	Dothistroma septosporum	66.33	0.00e+00	936.00
IUUC-Dme-031739	Drosophila melanogaster	31.59	2.00e-84	307.00
IUUC-Ete-032345	Echinops telfairi	34.07	2.00e-85	310.00
IUUC-Eca-033229	Equus caballus	39.56	1.00e-115	410.00
IUUC-Eeu-035205	Erinaceus europaeus	36.16	2.00e-114	406.00
IUUC-Fca-036444	Felis catus	39.56	1.00e-115	410.00
IUUC-Fal-037131	Ficedula albicollis	36.40	5.00e-117	414.00
IUUC-Fox-038035	Fusarium oxysporum	62.95	0.00e+00	872.00
IUUC-Fso-038320	Fusarium solani	62.94	0.00e+00	893.00
IUUC-Gmo-039497	Gadus morhua	37.18	5.00e-122	431.00
IUUC-Ggr-040057	Gaeumannomyces graminis	62.67	0.00e+00	874.00
IUUC-Gga-041021	Gallus gallus	35.70	3.00e-117	416.00
IUUC-Gac-042474	Gasterosteus aculeatus	37.33	6.00e-122	431.00
IUUC-Gma-044152	Glycine max	40.85	3.00e-114	405.00
IUUC-Ggo-044855	Gorilla gorilla	35.55	6.00e-116	411.00
IUUC-Hsa-046147	Homo sapiens	35.55	4.00e-116	411.00
IUUC-Hvu-047775	Hordeum vulgare	40.59	2.00e-110	392.00
IUUC-Itr-048131	Ictidomys tridecemlineatus	35.40	2.00e-115	409.00
IUUC-Kpa-049098	Komagataella pastoris	43.46	4.00e-126	444.00
IUUC-Lch-049818	Latimeria chalumnae	36.69	3.00e-114	405.00
IUUC-Lpe-051017	Leersia perrieri	38.47	1.00e-106	380.00
IUUC-Loc-051777	Lepisosteus oculatus	37.94	6.00e-124	437.00
IUUC-Lma-052990	Leptosphaeria maculans	67.70	0.00e+00	959.00
IUUC-Laf-053727	Loxodonta africana	35.70	3.00e-116	412.00
IUUC-Mcc-055799	Macaca mulatta	35.55	3.00e-116	412.00
IUUC-Meu-056065	Macropus eugenii	32.21	9.00e-88	317.00
IUUC-Mor-057054	Magnaporthe oryzae	63.45	0.00e+00	884.00
IUUC-Mpo-057417	Magnaporthe poae	64.08	0.00e+00	895.00
IUUC-Mtr-057849	Medicago truncatula	41.92	2.00e-117	416.00
IUUC-Mla-058870	Melampsora laricipopulina	46.42	2.00e-154	539.00
IUUC-Mga-059580	Meleagris gallopavo	31.37	3.00e-60	226.00
IUUC-Mvi-060507	Microbotryum violaceum	47.47	7.00e-175	607.00
IUUC-Mmr-060816	Microcebus murinus	35.85	4.00e-115	408.00
IUUC-Mdo-062866	Monodelphis domestica	32.50	4.00e-89	322.00
IUUC-Mmu-063906	Mus musculus	35.10	2.00e-114	406.00
IUUC-Mac-064675	Musa acuminata	39.75	8.00e-112	396.00
IUUC-Mpu-066199	Mustela putorius furo	36.01	1.00e-116	413.00
IUUC-Mlu-067110	Myotis lucifugus	35.44	2.00e-114	406.00
IUUC-Nfi-068482	Neosartorya fischeri	96.37	0.00e+00	3142.00
IUUC-Ncr-068906	Neurospora crassa	62.97	0.00e+00	908.00
IUUC-Nle-069410	Nomascus leucogenys	35.55	6.00e-116	411.00
IUUC-Opr-070401	Ochotona princeps	40.48	3.00e-55	209.00
IUUC-Ont-072100	Oreochromis niloticus	37.78	4.00e-122	431.00
IUUC-Oan-073121	Ornithorhynchus anatinus	35.25	3.00e-114	405.00
IUUC-Ocu-074623	Oryctolagus cuniculus	35.40	2.00e-115	409.00
IUUC-Oba-075380	Oryza barthii	35.43	4.00e-102	365.00
IUUC-Obr-076915	Oryza brachyantha	38.20	8.00e-105	374.00
IUUC-Ogl-077055	Oryza glaberrima	38.72	1.00e-104	373.00
IUUC-Ogu-078892	Oryza glumaepatula	35.28	1.00e-101	363.00
IUUC-Oin-079256	Oryza indica	38.27	1.00e-103	370.00
IUUC-Olo-080343	Oryza longistaminata	38.27	7.00e-104	370.00
IUUC-Ome-081422	Oryza meridionalis	38.27	8.00e-104	370.00
IUUC-Oni-083047	Oryza nivara	35.28	8.00e-103	367.00
IUUC-Opu-083641	Oryza punctata	34.45	3.00e-100	358.00
IUUC-Oru-084439	Oryza rufipogon	35.28	8.00e-102	363.00
IUUC-Osa-085972	Oryza sativa	38.32	1.00e-103	369.00
IUUC-Ola-087173	Oryzias latipes	37.33	5.00e-120	424.00
IUUC-Olu-087871	Ostreococcus lucimarinus	40.51	6.00e-105	372.00
IUUC-Oga-087908	Otolemur garnettii	35.40	6.00e-115	408.00
IUUC-Oar-090277	Ovis aries	35.70	2.00e-116	412.00
IUUC-Ptr-091543	Pan troglodytes	35.55	4.00e-116	411.00
IUUC-Pan-092243	Papio anubis	35.55	4.00e-116	412.00
IUUC-Psi-093150	Pelodiscus sinensis	36.16	5.00e-117	414.00
IUUC-Pno-094891	Phaeosphaeria nodorum	59.64	0.00e+00	1152.00
IUUC-Ppa-095181	Physcomitrella patens	43.92	1.00e-108	385.00
IUUC-Pfo-096267	Poecilia formosa	37.22	2.00e-120	426.00
IUUC-Pab-098072	Pongo abelii	35.55	6.00e-116	411.00
IUUC-Pop-099190	Populus trichocarpa	39.46	7.00e-113	400.00
IUUC-Pca-100311	Procavia capensis	39.74	1.00e-115	410.00
IUUC-Ppe-101284	Prunus persica	41.07	6.00e-115	407.00
IUUC-Pva-102215	Pteropus vampyrus	36.26	4.00e-100	358.00
IUUC-Pgr-103694	Puccinia graminis	46.65	4.00e-164	571.00
IUUC-Ptt-103916	Puccinia triticina	45.19	7.00e-154	537.00
IUUC-Pte-104346	Pyrenophora teres	61.81	0.00e+00	1210.00
IUUC-Pyt-104508	Pyrenophora triticirepentis	60.60	0.00e+00	1188.00
IUUC-Rno-105315	Rattus norvegicus	35.40	2.00e-115	409.00
IUUC-Sce-106273	Saccharomyces cerevisiae	41.21	6.00e-114	404.00
IUUC-Sha-106835	Sarcophilus harrisii	35.55	9.00e-116	410.00
IUUC-Sja-107943	Schizosaccharomyces japonicus	43.23	4.00e-142	497.00
IUUC-Spo-108081	Schizosaccharomyces pombe	51.94	8.00e-140	490.00
IUUC-Ssl-108560	Sclerotinia sclerotiorum	62.90	0.00e+00	1151.00
IUUC-Smo-109590	Selaginella moellendorffii	42.12	2.00e-109	389.00
IUUC-Sit-109757	Setaria italica	36.16	3.00e-110	392.00
IUUC-Sly-111557	Solanum lycopersicum	38.05	3.00e-119	422.00
IUUC-Stu-112896	Solanum tuberosum	37.66	8.00e-109	386.00
IUUC-Sar-113224	Sorex araneus	41.55	3.00e-85	309.00
IUUC-Sbi-114313	Sorghum bicolor	39.35	7.00e-112	397.00
IUUC-Sre-114993	Sporisorium reilianum	43.73	2.00e-161	562.00
IUUC-Ssc-115535	Sus scrofa	32.23	3.00e-93	336.00
IUUC-Tgu-117493	Taeniopygia guttata	31.37	4.00e-60	225.00
IUUC-Tru-118669	Takifugu rubripes	37.63	7.00e-122	431.00
IUUC-Tsy-119373	Tarsius syrichta	29.41	3.00e-71	263.00
IUUC-Tni-120049	Tetraodon nigroviridis	36.13	3.00e-87	314.00
IUUC-Tca-121779	Theobroma cacao	39.59	8.00e-110	390.00
IUUC-Tre-122195	Trichoderma reesei	55.80	0.00e+00	1085.00
IUUC-Tvi-122650	Trichoderma virens	55.69	0.00e+00	1102.00
IUUC-Tae-123120	Triticum aestivum	39.17	3.00e-113	402.00
IUUC-Tur-126295	Triticum urartu	40.42	6.00e-113	400.00
IUUC-Tme-126964	Tuber melanosporum	67.84	0.00e+00	914.00
IUUC-Tbe-128149	Tupaia belangeri	36.99	1.00e-66	248.00
IUUC-Ttr-128165	Tursiops truncatus	35.55	4.00e-116	411.00
IUUC-Uma-129365	Ustilago maydis	44.55	2.00e-149	522.00
IUUC-Vda-129725	Verticillium dahliae	68.44	0.00e+00	846.00
IUUC-Vpa-130678	Vicugna pacos	35.70	3.00e-116	412.00
IUUC-Vvi-131147	Vitis vinifera	39.56	1.00e-112	400.00
IUUC-Xtr-132636	Xenopus tropicalis	35.90	5.00e-114	405.00
IUUC-Xma-133458	Xiphophorus maculatus	37.58	5.00e-122	431.00
IUUC-Yli-134481	Yarrowia lipolytica	47.90	1.00e-157	549.00
IUUC-Zma-135657	Zea mays	39.17	7.00e-111	394.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence