iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-042550

Ensembl Protein ID

ENSGACP00000014545.1

UniProt Accession

G3PAC1; G3PAC1_GASAC

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000010969.1	ENSGACT00000014558.1	ENSGACP00000014532.1
ENSGACG00000010969.1	ENSGACT00000014563.1	ENSGACP00000014538.1
ENSGACG00000010969.1	ENSGACT00000014571.1	ENSGACP00000014545.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.60e-12	46.9	26	83

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 26   PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--RSKNGQGWVPSNYITPVN 83
           67899************************.*********98..788899*********997 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

VAPSLPPEAV RWSSKENLLG AAESDPNLFV ALYDFVASGD NTLSITKGEK LRVLGYNQNG 60
EWSEVRSKNG QGWVPSNYIT PVNSLEKHSW YHGPVSRSAA EYLLSSLING SFLVRESESS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACGCGTCCC AACCGCACCA AGCGAAGGGG AACCGGGGGA GCGCCGCCGG GAGGAGACCC 60
CGGGAACCCG GCAGCAGCAC GGGGACACCG CCAGGCAGGA CGGCTGCAGT CAACGTGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002263	Ailuropoda melanoleuca	68.95	0.00e+00	1357.00
IUUC-Apl-003389	Anas platyrhynchos	69.06	0.00e+00	1326.00
IUUC-Ame-010629	Astyanax mexicanus	64.44	0.00e+00	1178.00
IUUC-Bta-013370	Bos taurus	68.61	0.00e+00	1340.00
IUUC-Cja-018894	Callithrix jacchus	69.98	0.00e+00	1372.00
IUUC-Cfa-020398	Canis familiaris	86.46	0.00e+00	1068.00
IUUC-Cpo-022367	Cavia porcellus	78.33	0.00e+00	1209.00
IUUC-Csa-023386	Chlorocebus sabaeus	68.84	0.00e+00	1359.00
IUUC-Cho-024714	Choloepus hoffmanni	78.98	0.00e+00	1140.00
IUUC-Dre-027741	Danio rerio	76.21	0.00e+00	1536.00
IUUC-Dno-029246	Dasypus novemcinctus	68.28	0.00e+00	1330.00
IUUC-Dor-030416	Dipodomys ordii	63.72	0.00e+00	1194.00
IUUC-Ete-032899	Echinops telfairi	96.52	3.00e-124	439.00
IUUC-Eca-033387	Equus caballus	68.60	0.00e+00	1340.00
IUUC-Eeu-035058	Erinaceus europaeus	64.60	0.00e+00	1269.00
IUUC-Fca-036578	Felis catus	71.72	0.00e+00	1146.00
IUUC-Fal-037491	Ficedula albicollis	70.19	0.00e+00	1399.00
IUUC-Gmo-038509	Gadus morhua	83.56	0.00e+00	1405.00
IUUC-Gga-040638	Gallus gallus	69.46	0.00e+00	1355.00
IUUC-Ggo-044487	Gorilla gorilla	68.84	0.00e+00	1354.00
IUUC-Hsa-046636	Homo sapiens	69.01	0.00e+00	1354.00
IUUC-Itr-048685	Ictidomys tridecemlineatus	69.26	0.00e+00	1359.00
IUUC-Lch-049530	Latimeria chalumnae	74.58	0.00e+00	1290.00
IUUC-Loc-051933	Lepisosteus oculatus	76.32	0.00e+00	1496.00
IUUC-Laf-053802	Loxodonta africana	69.01	0.00e+00	1380.00
IUUC-Mcc-054836	Macaca mulatta	69.58	0.00e+00	1365.00
IUUC-Mga-059277	Meleagris gallopavo	69.63	0.00e+00	1367.00
IUUC-Mmr-061206	Microcebus murinus	68.89	0.00e+00	1302.00
IUUC-Mdo-062281	Monodelphis domestica	87.29	0.00e+00	1064.00
IUUC-Mmu-063847	Mus musculus	68.62	0.00e+00	1321.00
IUUC-Mpu-066309	Mustela putorius furo	86.62	0.00e+00	1069.00
IUUC-Mlu-068070	Myotis lucifugus	68.66	0.00e+00	1347.00
IUUC-Nle-070062	Nomascus leucogenys	86.95	0.00e+00	1070.00
IUUC-Ont-072440	Oreochromis niloticus	87.50	0.00e+00	1582.00
IUUC-Oan-073526	Ornithorhynchus anatinus	73.71	0.00e+00	1263.00
IUUC-Ocu-074051	Oryctolagus cuniculus	73.51	0.00e+00	1238.00
IUUC-Oni-082734	Oryza nivara	34.55	3.00e-24	107.00
IUUC-Opu-083538	Oryza punctata	35.00	6.00e-24	106.00
IUUC-Ola-086752	Oryzias latipes	97.63	0.00e+00	927.00
IUUC-Oga-088767	Otolemur garnettii	63.56	0.00e+00	1167.00
IUUC-Oar-089800	Ovis aries	68.58	0.00e+00	1338.00
IUUC-Ptr-090857	Pan troglodytes	86.79	0.00e+00	1070.00
IUUC-Pan-092279	Papio anubis	68.66	0.00e+00	1358.00
IUUC-Psi-093573	Pelodiscus sinensis	68.92	0.00e+00	1325.00
IUUC-Pfo-096543	Poecilia formosa	81.48	0.00e+00	1576.00
IUUC-Pab-097949	Pongo abelii	69.11	0.00e+00	1329.00
IUUC-Pca-100370	Procavia capensis	61.92	0.00e+00	923.00
IUUC-Pva-103220	Pteropus vampyrus	66.33	0.00e+00	1068.00
IUUC-Rno-105924	Rattus norvegicus	68.48	0.00e+00	1316.00
IUUC-Sha-107114	Sarcophilus harrisii	76.35	0.00e+00	1137.00
IUUC-Sit-110444	Setaria italica	34.17	8.00e-21	95.90
IUUC-Sbi-114480	Sorghum bicolor	32.88	4.00e-24	106.00
IUUC-Ssc-115968	Sus scrofa	73.45	0.00e+00	1271.00
IUUC-Tgu-117301	Taeniopygia guttata	69.95	0.00e+00	1384.00
IUUC-Tru-118410	Takifugu rubripes	85.34	0.00e+00	1756.00
IUUC-Tni-119991	Tetraodon nigroviridis	85.14	0.00e+00	1742.00
IUUC-Tca-121389	Theobroma cacao	33.85	2.00e-23	105.00
IUUC-Tae-122912	Triticum aestivum	30.14	2.00e-19	90.90
IUUC-Tur-126227	Triticum urartu	31.07	2.00e-17	84.00
IUUC-Tbe-127362	Tupaia belangeri	71.64	0.00e+00	1198.00
IUUC-Ttr-129291	Tursiops truncatus	69.48	0.00e+00	1351.00
IUUC-Vpa-130800	Vicugna pacos	77.78	0.00e+00	1196.00
IUUC-Xtr-132965	Xenopus tropicalis	70.78	0.00e+00	1120.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence