iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088049

Ensembl Protein ID

ENSOGAP00000013593.2

UniProt Accession

H0XCQ9; H0XCQ9_OTOGA

Genbank Protein ID

ENSOGAP00000013593

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03040890

Gene Name

NPLOC4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000015173.2	ENSOGAT00000015184.2	ENSOGAP00000013593.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	1.10e-12	47.3	579	606

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 2    eaqWaCsaCTflNePeavkCemCsrpRg 29
           +a+WaC++CTf+N+P +++CemCs pR+
   Q: 579  AAMWACQHCTFMNQPGTGHCEMCSLPRT 606
           689***********************95 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

IIRVQSPDGV KRITATKRET AATFLKKVAK EFGFQNNGFS VYINRNKTGE ITASSNKSLN 60
LLKINSGKGL RMIPREQLGP SSGLQPSLLF GIKSFEVFRC LDAERLEFLT DVLGRLHVAR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAATTCGTG TCCAGTCCCC GGATGGAGTG AAGCGGATCA CAGCAACAAA GAGAGAAACA 60
GCTGCAACAT TTTTGAAAAA GGTATCTGTG GCTTGGGTGT TTACCTCTTT TTATCTTCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR016563--Npl4
IPR007717--NPL4_C
IPR024682--Npl4_Ub-like_dom
IPR007716--NPL4_Zn-bd_put
IPR001876--Znf_RanBP2

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF05021--NPL4
PF11543--UN_NPL4
PF05020--zf-NPL4

SMART

SM00547--ZnF_RBZ

Gene Ontology

GO:0005634--C:nucleus
GO:0036501--C:UFD1-NPL4 complex
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0008270--F:zinc ion binding
GO:0039536--P:negative regulation of RIG-I signaling pathway
GO:0032480--P:negative regulation of type I interferon production
GO:0030970--P:retrograde protein transport, ER to cytosol
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000460	Aegilops tauschii	26.22	4.00e-09	55.80
IUUC-Aml-002268	Ailuropoda melanoleuca	82.84	0.00e+00	1017.00
IUUC-Atr-002939	Amborella trichopoda	25.37	4.00e-11	62.40
IUUC-Apl-003496	Anas platyrhynchos	75.94	0.00e+00	911.00
IUUC-Aca-005230	Anolis carolinensis	79.08	0.00e+00	993.00
IUUC-Aly-006056	Arabidopsis lyrata	28.36	4.00e-13	69.30
IUUC-Ath-006993	Arabidopsis thaliana	33.10	1.00e-11	63.90
IUUC-Ago-007954	Ashbya gossypii	35.81	2.00e-60	226.00
IUUC-Acl-008208	Aspergillus clavatus	35.96	3.00e-80	293.00
IUUC-Afl-008574	Aspergillus flavus	37.25	2.00e-74	273.00
IUUC-Afu-008825	Aspergillus fumigatus	36.38	6.00e-81	295.00
IUUC-Ani-009495	Aspergillus nidulans	36.83	1.00e-80	294.00
IUUC-Ang-009762	Aspergillus niger	35.63	9.00e-76	278.00
IUUC-Aor-010199	Aspergillus oryzae	36.91	5.00e-74	272.00
IUUC-Ate-010592	Aspergillus terreus	38.94	4.00e-78	285.00
IUUC-Ame-011587	Astyanax mexicanus	62.65	1.00e-83	304.00
IUUC-Bgr-012124	Blumeria graminis	33.55	5.00e-70	258.00
IUUC-Bta-013312	Bos taurus	83.50	0.00e+00	1051.00
IUUC-Bci-013648	Botrytis cinerea	35.67	5.00e-79	288.00
IUUC-Bdi-014326	Brachypodium distachyon	27.57	1.00e-09	57.40
IUUC-Bol-016294	Brassica oleracea	34.71	2.00e-11	63.20
IUUC-Bra-017023	Brassica rapa	34.71	3.00e-11	63.20
IUUC-Cel-018713	Caenorhabditis elegans	39.15	4.00e-112	398.00
IUUC-Cja-018869	Callithrix jacchus	83.83	0.00e+00	1032.00
IUUC-Cfa-020757	Canis familiaris	83.50	0.00e+00	1031.00
IUUC-Cpo-022390	Cavia porcellus	83.50	0.00e+00	1025.00
IUUC-Csa-023366	Chlorocebus sabaeus	83.99	0.00e+00	1056.00
IUUC-Cho-024455	Choloepus hoffmanni	77.62	0.00e+00	672.00
IUUC-Cin-025638	Ciona intestinalis	40.00	1.00e-118	419.00
IUUC-Csv-026310	Ciona savignyi	39.39	3.00e-109	389.00
IUUC-Cgl-026685	Colletotrichum gloeosporioides	35.13	2.00e-74	273.00
IUUC-Cne-026794	Cryptococcus neoformans	28.16	9.00e-54	204.00
IUUC-Cme-027248	Cyanidioschyzon merolae	33.33	7.00e-06	45.10
IUUC-Dre-027689	Danio rerio	69.28	0.00e+00	872.00
IUUC-Dno-030004	Dasypus novemcinctus	82.18	0.00e+00	1024.00
IUUC-Dor-030585	Dipodomys ordii	79.96	0.00e+00	805.00
IUUC-Dse-031202	Dothistroma septosporum	34.04	1.00e-74	273.00
IUUC-Dme-032092	Drosophila melanogaster	39.81	3.00e-139	488.00
IUUC-Ete-033009	Echinops telfairi	72.57	1.00e-71	263.00
IUUC-Eca-034001	Equus caballus	83.50	0.00e+00	1053.00
IUUC-Eeu-034485	Erinaceus europaeus	65.53	0.00e+00	654.00
IUUC-Fca-036128	Felis catus	83.66	0.00e+00	1016.00
IUUC-Fal-037523	Ficedula albicollis	78.58	0.00e+00	991.00
IUUC-Fox-037802	Fusarium oxysporum	35.44	6.00e-81	295.00
IUUC-Fso-038152	Fusarium solani	32.97	2.00e-80	293.00
IUUC-Gmo-038486	Gadus morhua	71.86	0.00e+00	733.00
IUUC-Ggr-039916	Gaeumannomyces graminis	34.51	2.00e-70	260.00
IUUC-Gga-041208	Gallus gallus	79.24	0.00e+00	1004.00
IUUC-Gac-042304	Gasterosteus aculeatus	67.47	0.00e+00	829.00
IUUC-Gma-044007	Glycine max	31.47	1.00e-09	57.40
IUUC-Ggo-045236	Gorilla gorilla	80.36	0.00e+00	999.00
IUUC-Hsa-046334	Homo sapiens	83.83	0.00e+00	1054.00
IUUC-Hvu-047323	Hordeum vulgare	37.74	2.00e-03	35.00
IUUC-Itr-047878	Ictidomys tridecemlineatus	86.76	0.00e+00	646.00
IUUC-Lch-050302	Latimeria chalumnae	71.59	0.00e+00	910.00
IUUC-Lpe-051362	Leersia perrieri	26.77	3.00e-11	62.80
IUUC-Loc-052548	Lepisosteus oculatus	70.29	0.00e+00	857.00
IUUC-Lma-053092	Leptosphaeria maculans	34.59	2.00e-80	293.00
IUUC-Laf-053911	Loxodonta africana	83.53	0.00e+00	1050.00
IUUC-Mcc-055830	Macaca mulatta	83.42	0.00e+00	1038.00
IUUC-Meu-056460	Macropus eugenii	61.78	1.00e-122	433.00
IUUC-Mor-057189	Magnaporthe oryzae	34.13	1.00e-74	273.00
IUUC-Mpo-057366	Magnaporthe poae	35.49	3.00e-71	262.00
IUUC-Mtr-057834	Medicago truncatula	35.77	8.00e-12	64.70
IUUC-Mla-059190	Melampsora laricipopulina	29.36	2.00e-65	243.00
IUUC-Mga-060036	Meleagris gallopavo	78.91	0.00e+00	1001.00
IUUC-Mvi-060275	Microbotryum violaceum	36.34	5.00e-61	229.00
IUUC-Mmr-061300	Microcebus murinus	83.99	0.00e+00	1053.00
IUUC-Mdo-062911	Monodelphis domestica	80.77	0.00e+00	868.00
IUUC-Mmu-063916	Mus musculus	83.33	0.00e+00	1032.00
IUUC-Mac-065601	Musa acuminata	37.66	2.00e-08	53.50
IUUC-Mpu-065912	Mustela putorius furo	83.33	0.00e+00	1030.00
IUUC-Mlu-067965	Myotis lucifugus	82.18	0.00e+00	1011.00
IUUC-Nfi-068465	Neosartorya fischeri	36.60	3.00e-81	296.00
IUUC-Ncr-068936	Neurospora crassa	35.87	3.00e-75	276.00
IUUC-Nle-069570	Nomascus leucogenys	83.50	0.00e+00	1048.00
IUUC-Opr-071097	Ochotona princeps	75.05	0.00e+00	749.00
IUUC-Ont-071430	Oreochromis niloticus	68.59	0.00e+00	865.00
IUUC-Oan-073709	Ornithorhynchus anatinus	67.42	0.00e+00	632.00
IUUC-Ocu-074875	Oryctolagus cuniculus	78.88	0.00e+00	979.00
IUUC-Oba-075214	Oryza barthii	26.02	4.00e-11	62.40
IUUC-Obr-076758	Oryza brachyantha	27.68	2.00e-11	62.80
IUUC-Ogl-077665	Oryza glaberrima	26.02	4.00e-11	62.40
IUUC-Ogu-078899	Oryza glumaepatula	26.02	4.00e-11	62.40
IUUC-Oin-079167	Oryza indica	26.02	4.00e-11	62.40
IUUC-Olo-080451	Oryza longistaminata	26.02	3.00e-11	62.40
IUUC-Ome-081836	Oryza meridionalis	26.02	7.00e-11	61.60
IUUC-Oni-083019	Oryza nivara	26.02	4.00e-11	62.40
IUUC-Opu-083122	Oryza punctata	26.59	2.00e-11	63.50
IUUC-Oru-084900	Oryza rufipogon	26.02	4.00e-11	62.40
IUUC-Osa-086054	Oryza sativa	26.02	4.00e-11	62.40
IUUC-Ola-087077	Oryzias latipes	60.22	0.00e+00	724.00
IUUC-Oar-089678	Ovis aries	83.50	0.00e+00	1052.00
IUUC-Ptr-091380	Pan troglodytes	82.38	0.00e+00	950.00
IUUC-Pan-092821	Papio anubis	82.84	0.00e+00	1040.00
IUUC-Psi-093074	Pelodiscus sinensis	79.28	0.00e+00	993.00
IUUC-Pma-094102	Petromyzon marinus	59.06	0.00e+00	761.00
IUUC-Pno-094987	Phaeosphaeria nodorum	34.53	2.00e-77	284.00
IUUC-Ppa-095368	Physcomitrella patens	26.92	8.00e-11	61.20
IUUC-Pfo-097245	Poecilia formosa	68.97	0.00e+00	838.00
IUUC-Pab-098763	Pongo abelii	83.99	0.00e+00	1056.00
IUUC-Pop-099355	Populus trichocarpa	32.37	4.00e-11	62.00
IUUC-Ppe-101990	Prunus persica	34.72	4.00e-12	65.90
IUUC-Pva-102308	Pteropus vampyrus	72.73	0.00e+00	778.00
IUUC-Pgr-103553	Puccinia graminis	30.59	7.00e-59	221.00
IUUC-Pte-104100	Pyrenophora teres	33.63	7.00e-74	271.00
IUUC-Pyt-104482	Pyrenophora triticirepentis	33.85	2.00e-75	276.00
IUUC-Rno-105582	Rattus norvegicus	83.17	0.00e+00	1030.00
IUUC-Sce-106145	Saccharomyces cerevisiae	34.35	1.00e-72	267.00
IUUC-Sha-106647	Sarcophilus harrisii	81.28	0.00e+00	1006.00
IUUC-Sja-107972	Schizosaccharomyces japonicus	36.96	5.00e-69	255.00
IUUC-Spo-108281	Schizosaccharomyces pombe	35.17	3.00e-73	269.00
IUUC-Ssl-108617	Sclerotinia sclerotiorum	35.01	6.00e-77	281.00
IUUC-Smo-108933	Selaginella moellendorffii	29.36	3.00e-13	69.30
IUUC-Sit-110083	Setaria italica	25.72	3.00e-10	59.70
IUUC-Sly-111645	Solanum lycopersicum	32.92	9.00e-13	67.80
IUUC-Stu-112422	Solanum tuberosum	32.92	5.00e-13	68.60
IUUC-Sbi-113987	Sorghum bicolor	26.94	4.00e-11	62.80
IUUC-Sre-115095	Sporisorium reilianum	34.01	2.00e-63	237.00
IUUC-Ssc-116141	Sus scrofa	80.56	0.00e+00	917.00
IUUC-Tgu-117492	Taeniopygia guttata	74.34	0.00e+00	692.00
IUUC-Tru-118463	Takifugu rubripes	66.67	0.00e+00	813.00
IUUC-Tsy-118993	Tarsius syrichta	73.84	0.00e+00	824.00
IUUC-Tni-119896	Tetraodon nigroviridis	68.53	0.00e+00	825.00
IUUC-Tca-121169	Theobroma cacao	34.31	8.00e-14	71.20
IUUC-Tre-122046	Trichoderma reesei	35.54	1.00e-77	284.00
IUUC-Tvi-122415	Trichoderma virens	35.63	2.00e-77	283.00
IUUC-Tae-123514	Triticum aestivum	26.22	2.00e-09	57.00
IUUC-Tme-127123	Tuber melanosporum	37.84	5.00e-80	292.00
IUUC-Tbe-127629	Tupaia belangeri	79.21	7.00e-131	460.00
IUUC-Ttr-128476	Tursiops truncatus	71.53	0.00e+00	786.00
IUUC-Uma-129492	Ustilago maydis	34.34	1.00e-64	241.00
IUUC-Vda-129702	Verticillium dahliae	33.92	2.00e-74	273.00
IUUC-Vvi-131090	Vitis vinifera	30.00	9.00e-11	61.20
IUUC-Xtr-131786	Xenopus tropicalis	73.44	0.00e+00	907.00
IUUC-Xma-133997	Xiphophorus maculatus	71.66	0.00e+00	746.00
IUUC-Yli-134537	Yarrowia lipolytica	34.02	2.00e-69	256.00
IUUC-Zma-134847	Zea mays	27.82	2.00e-12	66.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence