iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-087954

Ensembl Protein ID

ENSOGAP00000002553.2

UniProt Accession

H0WLL1; H0WLL1_OTOGA

Genbank Protein ID

ENSOGAP00000002553

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AAQR03157649

Gene Name

ING1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000002849.2	ENSOGAT00000002853.2	ENSOGAP00000002553.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.80e-09	36.3	211	258

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 211  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 258
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MLSPANGEQV HLVNYVEDYL DSIESLPFDL QRNVSLMREI DAKYQEILKE LDEYYERFKR 60
EADGAQKRRV LHCIQRALIR SQELGDEKIQ IVSQMVELVE NRARQVDSHV ELFEAHQEVS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGAGTC CTGCCAACGG AGAGCAGGTC CACCTGGTGA ACTATGTGGA GGACTACCTG 60
GACTCCATCG AGTCTCTGCC TTTCGACTTG CAGAGGAACG TCTCGCTGAT GCGGGAGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006606--P:protein import into nucleus
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	94.98	3.00e-132	464.00
IUUC-Apl-003910	Anas platyrhynchos	92.09	3.00e-126	444.00
IUUC-Aca-004874	Anolis carolinensis	91.07	6.00e-124	436.00
IUUC-Acl-008091	Aspergillus clavatus	52.11	5.00e-19	89.70
IUUC-Ame-011262	Astyanax mexicanus	66.90	5.00e-96	343.00
IUUC-Bta-013507	Bos taurus	91.88	1.00e-95	342.00
IUUC-Cja-018925	Callithrix jacchus	90.68	2.00e-124	438.00
IUUC-Cfa-020947	Canis familiaris	94.62	1.00e-130	458.00
IUUC-Cpo-022286	Cavia porcellus	91.53	3.00e-101	361.00
IUUC-Csa-023825	Chlorocebus sabaeus	90.32	6.00e-124	436.00
IUUC-Cho-024577	Choloepus hoffmanni	93.99	2.00e-102	364.00
IUUC-Cne-027005	Cryptococcus neoformans	45.95	3.00e-16	79.30
IUUC-Dno-029834	Dasypus novemcinctus	94.27	7.00e-131	459.00
IUUC-Dor-030315	Dipodomys ordii	91.03	1.00e-111	396.00
IUUC-Ete-032408	Echinops telfairi	91.49	4.00e-97	347.00
IUUC-Eca-034244	Equus caballus	93.59	5.00e-104	370.00
IUUC-Fca-035391	Felis catus	89.58	6.00e-112	396.00
IUUC-Fal-036838	Ficedula albicollis	91.04	2.00e-125	441.00
IUUC-Fox-037925	Fusarium oxysporum	64.71	8.00e-20	91.30
IUUC-Gga-040619	Gallus gallus	92.11	2.00e-126	444.00
IUUC-Gac-041996	Gasterosteus aculeatus	64.18	3.00e-94	337.00
IUUC-Ggo-045481	Gorilla gorilla	87.71	7.00e-97	347.00
IUUC-Hsa-046170	Homo sapiens	87.71	8.00e-97	347.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	95.30	2.00e-105	374.00
IUUC-Lch-050397	Latimeria chalumnae	87.81	3.00e-122	431.00
IUUC-Loc-052038	Lepisosteus oculatus	80.62	2.00e-100	357.00
IUUC-Laf-054126	Loxodonta africana	95.70	1.00e-132	465.00
IUUC-Mcc-055031	Macaca mulatta	88.09	2.00e-96	345.00
IUUC-Meu-056248	Macropus eugenii	91.18	2.00e-100	358.00
IUUC-Mga-059217	Meleagris gallopavo	90.99	1.00e-98	352.00
IUUC-Mmr-061581	Microcebus murinus	95.88	3.00e-111	394.00
IUUC-Mdo-062452	Monodelphis domestica	93.55	9.00e-129	452.00
IUUC-Mmu-063412	Mus musculus	95.34	9.00e-133	465.00
IUUC-Mpu-066479	Mustela putorius furo	94.44	2.00e-104	372.00
IUUC-Mlu-067586	Myotis lucifugus	80.07	5.00e-119	420.00
IUUC-Nle-069122	Nomascus leucogenys	89.96	2.00e-123	434.00
IUUC-Opr-070835	Ochotona princeps	87.12	1.00e-88	318.00
IUUC-Oan-073023	Ornithorhynchus anatinus	91.04	5.00e-124	436.00
IUUC-Ocu-073779	Oryctolagus cuniculus	89.58	7.00e-97	346.00
IUUC-Ola-086891	Oryzias latipes	65.36	1.00e-94	338.00
IUUC-Oar-090006	Ovis aries	93.19	6.00e-129	452.00
IUUC-Ptr-090589	Pan troglodytes	90.32	4.00e-124	437.00
IUUC-Pan-091896	Papio anubis	88.09	2.00e-96	346.00
IUUC-Psi-093266	Pelodiscus sinensis	92.83	5.00e-128	450.00
IUUC-Pma-094265	Petromyzon marinus	72.00	4.00e-33	133.00
IUUC-Pfo-097531	Poecilia formosa	60.71	5.00e-92	330.00
IUUC-Pab-098253	Pongo abelii	90.32	7.00e-124	436.00
IUUC-Pva-102753	Pteropus vampyrus	83.01	7.00e-92	330.00
IUUC-Rno-105964	Rattus norvegicus	94.02	5.00e-93	333.00
IUUC-Sha-107270	Sarcophilus harrisii	92.83	3.00e-127	447.00
IUUC-Tgu-116822	Taeniopygia guttata	91.40	9.00e-126	442.00
IUUC-Tni-119980	Tetraodon nigroviridis	57.00	1.00e-81	296.00
IUUC-Tre-121950	Trichoderma reesei	64.29	2.00e-19	91.70
IUUC-Tvi-122341	Trichoderma virens	62.50	3.00e-16	77.40
IUUC-Ttr-128672	Tursiops truncatus	92.77	1.00e-102	365.00
IUUC-Xtr-132200	Xenopus tropicalis	83.51	1.00e-114	405.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence