iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133491

Ensembl Protein ID

ENSXMAP00000012158.1

UniProt Accession

M4ACG4; M4ACG4_XIPMA

Genbank Protein ID

ENSXMAP00000012158

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AGAJ01005595

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000012139.1	ENSXMAT00000012174.1	ENSXMAP00000012158.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.20e-08	34.2	236	283

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C  ewfH+ C++l     +p+ + w+CpkCr 
   Q: 236  TYC-LCEQVSYGE--MIGCDNdeCPiEWFHFSCVGLH---HKPKGK-WYCPKCRG 283
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MLNPSNGDPG HVVVNYVEEY LDLVESLPFD LQRSVSLMRE IDAKYQDALK ELDDAYERYR 60
RELDSLQRRK LQLSIQRALI RSQELGDEKI QIAGQMVELV ENRTRQMEWH SELLLSSQEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACTTATACA AGTCAGAAAA TTATGAAATA GTGTACTATC CAATGCAAGT TGTGTTGCAT 60
TGAGGGGAAG GTGTTGCTGC CGTAATTTCA GGGTCTTTAT TCTACAGACT GCAGCAGTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0010941--P:regulation of cell death

KEGG

xma:102234344

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	58.55	2.00e-87	315.00
IUUC-Ame-011262	Astyanax mexicanus	63.07	7.00e-89	320.00
IUUC-Cfa-020663	Canis familiaris	57.57	2.00e-85	308.00
IUUC-Cpo-022286	Cavia porcellus	55.00	1.00e-64	239.00
IUUC-Cho-024577	Choloepus hoffmanni	54.69	3.00e-62	231.00
IUUC-Cne-027005	Cryptococcus neoformans	49.25	1.00e-16	80.50
IUUC-Dno-029834	Dasypus novemcinctus	57.89	2.00e-84	305.00
IUUC-Dor-030315	Dipodomys ordii	59.53	2.00e-71	262.00
IUUC-Eca-034244	Equus caballus	55.43	4.00e-65	240.00
IUUC-Fca-035391	Felis catus	54.80	3.00e-70	257.00
IUUC-Fox-037925	Fusarium oxysporum	69.57	1.00e-19	91.30
IUUC-Gac-041996	Gasterosteus aculeatus	82.95	2.00e-128	451.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	55.04	3.00e-66	244.00
IUUC-Lch-050397	Latimeria chalumnae	63.28	1.00e-87	316.00
IUUC-Loc-052038	Lepisosteus oculatus	63.48	1.00e-79	289.00
IUUC-Laf-054126	Loxodonta africana	58.88	1.00e-87	316.00
IUUC-Mmr-061581	Microcebus murinus	56.93	3.00e-71	261.00
IUUC-Mdo-062452	Monodelphis domestica	58.22	3.00e-87	314.00
IUUC-Mmu-063412	Mus musculus	57.89	5.00e-86	310.00
IUUC-Mpu-066479	Mustela putorius furo	55.43	4.00e-66	244.00
IUUC-Mlu-067586	Myotis lucifugus	53.42	3.00e-79	288.00
IUUC-Opr-070835	Ochotona princeps	88.75	2.00e-43	168.00
IUUC-Ont-071606	Oreochromis niloticus	89.54	2.00e-127	448.00
IUUC-Ola-086891	Oryzias latipes	83.55	3.00e-124	437.00
IUUC-Oga-087954	Otolemur garnettii	57.89	2.00e-85	308.00
IUUC-Pma-094265	Petromyzon marinus	74.39	2.00e-34	137.00
IUUC-Pfo-097531	Poecilia formosa	98.70	2.00e-157	548.00
IUUC-Sha-107270	Sarcophilus harrisii	58.88	1.00e-87	315.00
IUUC-Sre-115124	Sporisorium reilianum	58.18	7.00e-21	95.90
IUUC-Tru-118262	Takifugu rubripes	85.39	3.00e-112	397.00
IUUC-Tni-119980	Tetraodon nigroviridis	88.24	9.00e-123	432.00
IUUC-Tre-121950	Trichoderma reesei	64.29	2.00e-19	90.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence