iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132094

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAMC01042687

Gene Name

ube3c

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000021620.3	ENSXETT00000046726.3	ENSXETP00000046726.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.60e-104	349.4	747	1084

Active Site

Position(s)	Description	Evidence
1052	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
            dlkkr++v++++     E+g+d gG++refl++l+k  +np+ g+f++++++    +p+ ++ + +    ++++flGr+lgkal++
   Q: 747  PDLKKRIRVHLLNthgldEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAQMLVGD-SFARHYYFLGRMLGKALYE 832
           689*********9999*9************************************9999999999965.999**************** PP
   S: 85   grlldlplsksfyklllgk..klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneN 169
           + l++lp++++f+++llg+  ++++++l+++dpe+y++l ++k++ e+d+eelgl++t+   ++ lge++++eLk gG++ipVt +N
   Q: 833  NMLVELPFASFFLSKLLGTsaDVDIHHLASLDPEMYRNLLFLKSY-EDDVEELGLNFTV--VNNDLGEAQVVELKAGGKDIPVTSAN 916
           ******************9666889********************.6788887666665..5889********************** PP
   S: 170  keeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevlee 255
           + +Y++lv++yrl+++i+ ++ afr+G+ +v++le+l++F+++el++li+G    i ++dlk++t+y ggy++d+ +i+ Fw+v+e+
   Q: 917  RIAYIHLVADYRLNKQIRPHCLAFRQGLANVVNLEWLRMFDQQELQVLISGAqVPICLDDLKSFTNYSGGYSADHAVIKIFWRVVEN 1003
           ****************************************************899******************************** PP
   S: 256  fsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           f++ee++++L+FvT++sr Pl Gf+el p  f+i++ +sd +rlP+++TC+n+LkLPe+  +  +k+kLlyAie ++gFels
   Q: 1004 FTDEEKRKLLKFVTSCSRPPLLGFKELYPA-FCIHNGGSDlERLPTASTCMNLLKLPEFYDEHLMKSKLLYAIECAAGFELS 1084
           ****************************88.*****99999**************************************985 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MFSFEGDFKT RPKVSLRGAS KKEDKASLLH RTQEERRKRE EERRRLKNAI IIQSFVRGYK 60
DRKQQYTIQR SEFDSCASSA AANGGATNGS NLVLLVRKLL FFYRQNEDSK RLIWICQNLI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCGGAGCG GCTCCTGTTG TTGCTGTGCG GCGCCCAGTG TGAGATTTCG GCAGGTAACC 60
AGTCTTCCGG TGGGCACCTG TCAGGGGTCA GAGCTGCCTT TGGGTAGGGA GTGGGTACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT
PF00612--IQ

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001355	Ailuropoda melanoleuca	84.00	0.00e+00	1736.00
IUUC-Apl-003731	Anas platyrhynchos	89.05	0.00e+00	1875.00
IUUC-Aca-005248	Anolis carolinensis	87.57	0.00e+00	1869.00
IUUC-Aly-005768	Arabidopsis lyrata	35.62	2.00e-106	380.00
IUUC-Ago-007748	Ashbya gossypii	40.71	2.00e-75	276.00
IUUC-Acl-008158	Aspergillus clavatus	37.95	1.00e-75	278.00
IUUC-Afl-008398	Aspergillus flavus	37.45	1.00e-75	278.00
IUUC-Afu-008937	Aspergillus fumigatus	38.43	5.00e-78	286.00
IUUC-Ani-009252	Aspergillus nidulans	37.58	4.00e-79	290.00
IUUC-Ang-009773	Aspergillus niger	33.73	2.00e-78	287.00
IUUC-Aor-009940	Aspergillus oryzae	37.45	1.00e-75	278.00
IUUC-Ate-010395	Aspergillus terreus	33.57	7.00e-77	282.00
IUUC-Ame-010769	Astyanax mexicanus	62.75	0.00e+00	1025.00
IUUC-Bgr-012269	Blumeria graminis	38.48	1.00e-74	273.00
IUUC-Bta-012841	Bos taurus	83.53	0.00e+00	1760.00
IUUC-Bci-013743	Botrytis cinerea	29.17	6.00e-83	302.00
IUUC-Bdi-014123	Brachypodium distachyon	46.57	1.00e-102	367.00
IUUC-Bol-015390	Brassica oleracea	46.12	4.00e-101	362.00
IUUC-Bra-016853	Brassica rapa	46.84	1.00e-106	380.00
IUUC-Cel-018638	Caenorhabditis elegans	39.37	9.00e-90	325.00
IUUC-Cja-019743	Callithrix jacchus	83.23	0.00e+00	1740.00
IUUC-Cfa-021031	Canis familiaris	85.32	0.00e+00	1791.00
IUUC-Cpo-022401	Cavia porcellus	85.27	0.00e+00	1780.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	43.99	3.00e-84	305.00
IUUC-Csa-024107	Chlorocebus sabaeus	85.73	0.00e+00	1805.00
IUUC-Cho-024750	Choloepus hoffmanni	79.79	0.00e+00	771.00
IUUC-Cin-025432	Ciona intestinalis	45.12	1.00e-96	346.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	33.45	9.00e-84	305.00
IUUC-Cne-026841	Cryptococcus neoformans	37.13	8.00e-95	342.00
IUUC-Cme-027265	Cyanidioschyzon merolae	47.58	2.00e-105	376.00
IUUC-Dre-028196	Danio rerio	77.37	0.00e+00	1575.00
IUUC-Dno-029024	Dasypus novemcinctus	86.00	0.00e+00	1818.00
IUUC-Dor-030483	Dipodomys ordii	86.68	0.00e+00	658.00
IUUC-Dse-031416	Dothistroma septosporum	34.59	5.00e-79	289.00
IUUC-Dme-031946	Drosophila melanogaster	37.87	0.00e+00	678.00
IUUC-Ete-032240	Echinops telfairi	77.16	3.00e-167	582.00
IUUC-Eca-033828	Equus caballus	85.43	0.00e+00	1771.00
IUUC-Eeu-034604	Erinaceus europaeus	83.46	7.00e-125	441.00
IUUC-Fca-035907	Felis catus	84.81	0.00e+00	1793.00
IUUC-Fal-037389	Ficedula albicollis	89.23	0.00e+00	1900.00
IUUC-Fox-037788	Fusarium oxysporum	37.25	6.00e-92	332.00
IUUC-Fso-038088	Fusarium solani	35.83	1.00e-87	318.00
IUUC-Gmo-039254	Gadus morhua	67.20	0.00e+00	1217.00
IUUC-Ggr-039941	Gaeumannomyces graminis	33.57	4.00e-80	293.00
IUUC-Gga-040310	Gallus gallus	88.95	0.00e+00	1884.00
IUUC-Gac-042054	Gasterosteus aculeatus	69.77	0.00e+00	1268.00
IUUC-Gma-042836	Glycine max	29.74	1.00e-102	367.00
IUUC-Ggo-045031	Gorilla gorilla	86.00	0.00e+00	1810.00
IUUC-Hsa-045880	Homo sapiens	85.91	0.00e+00	1809.00
IUUC-Itr-048555	Ictidomys tridecemlineatus	72.10	1.00e-159	556.00
IUUC-Kpa-049307	Komagataella pastoris	36.99	4.00e-66	246.00
IUUC-Lch-050403	Latimeria chalumnae	82.26	0.00e+00	1669.00
IUUC-Lpe-051428	Leersia perrieri	46.15	2.00e-96	347.00
IUUC-Loc-052218	Lepisosteus oculatus	81.53	0.00e+00	1689.00
IUUC-Lma-053096	Leptosphaeria maculans	38.36	1.00e-79	291.00
IUUC-Laf-054162	Loxodonta africana	82.97	0.00e+00	1544.00
IUUC-Mcc-055127	Macaca mulatta	85.73	0.00e+00	1805.00
IUUC-Meu-056187	Macropus eugenii	82.61	2.00e-106	379.00
IUUC-Mor-057021	Magnaporthe oryzae	33.86	8.00e-78	285.00
IUUC-Mpo-057570	Magnaporthe poae	36.24	4.00e-75	276.00
IUUC-Mla-059124	Melampsora laricipopulina	47.54	2.00e-101	362.00
IUUC-Mga-059581	Meleagris gallopavo	88.61	0.00e+00	1870.00
IUUC-Mvi-060445	Microbotryum violaceum	37.54	9.00e-103	368.00
IUUC-Mmr-061360	Microcebus murinus	82.17	0.00e+00	1666.00
IUUC-Mdo-062194	Monodelphis domestica	84.87	0.00e+00	1864.00
IUUC-Mmu-064189	Mus musculus	84.62	0.00e+00	1795.00
IUUC-Mac-065275	Musa acuminata	49.14	2.00e-108	386.00
IUUC-Mpu-066439	Mustela putorius furo	83.94	0.00e+00	1737.00
IUUC-Mlu-068228	Myotis lucifugus	82.58	0.00e+00	1735.00
IUUC-Nfi-068280	Neosartorya fischeri	38.64	2.00e-78	288.00
IUUC-Ncr-068869	Neurospora crassa	35.09	3.00e-81	297.00
IUUC-Nle-069687	Nomascus leucogenys	85.34	0.00e+00	1754.00
IUUC-Opr-070592	Ochotona princeps	94.00	1.00e-110	394.00
IUUC-Ont-071836	Oreochromis niloticus	79.28	0.00e+00	1649.00
IUUC-Oan-072800	Ornithorhynchus anatinus	88.67	0.00e+00	1890.00
IUUC-Ocu-074587	Oryctolagus cuniculus	86.19	0.00e+00	1818.00
IUUC-Ola-087209	Oryzias latipes	77.99	0.00e+00	1597.00
IUUC-Olu-087699	Ostreococcus lucimarinus	42.59	2.00e-86	311.00
IUUC-Oga-088776	Otolemur garnettii	81.31	0.00e+00	1651.00
IUUC-Oar-089441	Ovis aries	83.18	0.00e+00	1741.00
IUUC-Ptr-091273	Pan troglodytes	85.91	0.00e+00	1810.00
IUUC-Pan-091981	Papio anubis	85.82	0.00e+00	1806.00
IUUC-Psi-093203	Pelodiscus sinensis	88.00	0.00e+00	1636.00
IUUC-Pma-094738	Petromyzon marinus	64.75	0.00e+00	1324.00
IUUC-Pno-095132	Phaeosphaeria nodorum	34.17	6.00e-56	212.00
IUUC-Pfo-097511	Poecilia formosa	79.93	0.00e+00	1666.00
IUUC-Pab-098634	Pongo abelii	83.16	0.00e+00	1736.00
IUUC-Pop-098928	Populus trichocarpa	46.78	7.00e-97	348.00
IUUC-Pca-100987	Procavia capensis	95.82	0.00e+00	773.00
IUUC-Pva-103034	Pteropus vampyrus	79.98	0.00e+00	1640.00
IUUC-Pgr-103513	Puccinia graminis	38.38	8.00e-103	368.00
IUUC-Ptt-103967	Puccinia triticina	40.73	3.00e-91	330.00
IUUC-Pte-104105	Pyrenophora teres	37.72	6.00e-78	285.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	37.50	9.00e-78	285.00
IUUC-Rno-105380	Rattus norvegicus	83.42	0.00e+00	1542.00
IUUC-Sce-106446	Saccharomyces cerevisiae	41.01	5.00e-68	252.00
IUUC-Sha-107108	Sarcophilus harrisii	81.71	0.00e+00	1717.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	43.64	5.00e-94	339.00
IUUC-Spo-108097	Schizosaccharomyces pombe	43.63	5.00e-93	335.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	28.76	2.00e-80	294.00
IUUC-Sar-113687	Sorex araneus	79.17	0.00e+00	883.00
IUUC-Sre-115038	Sporisorium reilianum	43.73	5.00e-96	346.00
IUUC-Ssc-115378	Sus scrofa	92.84	0.00e+00	732.00
IUUC-Tgu-116729	Taeniopygia guttata	88.86	0.00e+00	1885.00
IUUC-Tru-118068	Takifugu rubripes	77.07	0.00e+00	1598.00
IUUC-Tsy-118942	Tarsius syrichta	83.37	0.00e+00	662.00
IUUC-Tni-120732	Tetraodon nigroviridis	76.12	0.00e+00	1560.00
IUUC-Tre-121892	Trichoderma reesei	36.06	7.00e-87	315.00
IUUC-Tvi-122354	Trichoderma virens	35.33	4.00e-87	316.00
IUUC-Tme-127102	Tuber melanosporum	35.71	2.00e-92	333.00
IUUC-Tbe-127351	Tupaia belangeri	74.90	0.00e+00	1404.00
IUUC-Ttr-129061	Tursiops truncatus	81.49	0.00e+00	1696.00
IUUC-Uma-129343	Ustilago maydis	44.47	2.00e-98	353.00
IUUC-Vda-129748	Verticillium dahliae	37.50	4.00e-78	286.00
IUUC-Xma-133923	Xiphophorus maculatus	80.11	0.00e+00	1668.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence