iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107300

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01223499

Gene Name

SYVN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000000784.1	ENSSHAT00000000888.1	ENSSHAP00000000877.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.80e-09	38.1	217	256

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC+e++ +g + lpC+H+fh++Cl  w       +++++CP+Cr
   Q: 217  CIICREEMVTGAKRLPCNHIFHTSCLRSW------FQRQQTCPTCR 256
           ********99999****************......**********8 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

QHLLERSWYA VTETCLAFTV FRDDFSPRFV ALFTLLLFLK CFHWLAEDRV DFMERSPNIS 60
WLFHCRIVSL MLLLGALDFL FVNHAYHSIL TRGASVQLVF GFEYAILMTM VLTIFIKYVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCGGGGTG GGGGACCAGC TGTCTCTGAG TGTTGTGGGA CGCTGAGGTC CCGGTGCCTG 60
GGGCAGTCCT TGGGTTGGGG GCCAAGCGGG GAGGTGGCAC GGGGGACCAG TCGTCCGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR032832--E3_lig_synoviolin/Hrd1
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0000839--C:Hrd1p ubiquitin ligase ERAD-L complex
GO:0016021--C:integral component of membrane
GO:0005654--C:nucleoplasm
GO:0005790--C:smooth endoplasmic reticulum
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0008270--F:zinc ion binding
GO:1902236--P:negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:0070936--P:protein K48-linked ubiquitination
GO:0018279--P:protein N-linked glycosylation via asparagine
GO:0050821--P:protein stabilization
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030970--P:retrograde protein transport, ER to cytosol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000344	Aegilops tauschii	37.72	1.00e-39	157.00
IUUC-Aml-001539	Ailuropoda melanoleuca	96.97	8.00e-157	546.00
IUUC-Atr-002892	Amborella trichopoda	44.06	1.00e-62	233.00
IUUC-Apl-004003	Anas platyrhynchos	96.61	7.00e-65	238.00
IUUC-Aca-004799	Anolis carolinensis	96.27	2.00e-157	548.00
IUUC-Aly-006352	Arabidopsis lyrata	44.83	6.00e-63	234.00
IUUC-Ath-006773	Arabidopsis thaliana	43.59	4.00e-63	235.00
IUUC-Ago-007894	Ashbya gossypii	24.24	8.00e-16	78.60
IUUC-Acl-008041	Aspergillus clavatus	30.72	6.00e-48	185.00
IUUC-Afl-008427	Aspergillus flavus	31.58	2.00e-48	187.00
IUUC-Afu-009023	Aspergillus fumigatus	30.86	4.00e-49	189.00
IUUC-Ani-009133	Aspergillus nidulans	31.67	1.00e-49	191.00
IUUC-Ang-009612	Aspergillus niger	36.01	4.00e-49	189.00
IUUC-Aor-010045	Aspergillus oryzae	31.58	4.00e-48	186.00
IUUC-Ate-010533	Aspergillus terreus	32.01	2.00e-48	187.00
IUUC-Ame-011083	Astyanax mexicanus	92.78	3.00e-149	521.00
IUUC-Bgr-012122	Blumeria graminis	27.40	4.00e-38	153.00
IUUC-Bta-013375	Bos taurus	97.32	9.00e-156	543.00
IUUC-Bci-013675	Botrytis cinerea	37.25	1.00e-23	104.00
IUUC-Bdi-015070	Brachypodium distachyon	44.83	1.00e-56	214.00
IUUC-Bol-015674	Brassica oleracea	44.83	9.00e-64	237.00
IUUC-Bra-017516	Brassica rapa	41.73	5.00e-61	228.00
IUUC-Cel-018422	Caenorhabditis elegans	61.30	1.00e-96	346.00
IUUC-Cja-019779	Callithrix jacchus	93.96	2.00e-146	512.00
IUUC-Cfa-020189	Canis familiaris	97.32	1.00e-155	543.00
IUUC-Cpo-022209	Cavia porcellus	96.97	4.00e-156	544.00
IUUC-Cre-022743	Chlamydomonas reinhardtii	41.86	4.00e-56	211.00
IUUC-Csa-023571	Chlorocebus sabaeus	97.32	1.00e-155	543.00
IUUC-Cho-024889	Choloepus hoffmanni	84.41	2.00e-132	466.00
IUUC-Csv-026160	Ciona savignyi	60.22	4.00e-96	345.00
IUUC-Cne-027002	Cryptococcus neoformans	40.69	6.00e-66	245.00
IUUC-Cme-027285	Cyanidioschyzon merolae	37.46	1.00e-49	191.00
IUUC-Dre-027999	Danio rerio	92.40	2.00e-150	526.00
IUUC-Dno-029250	Dasypus novemcinctus	97.35	2.00e-157	548.00
IUUC-Dor-030718	Dipodomys ordii	96.59	4.00e-156	544.00
IUUC-Dse-031498	Dothistroma septosporum	34.76	2.00e-27	117.00
IUUC-Dme-031969	Drosophila melanogaster	67.43	2.00e-114	406.00
IUUC-Ete-032592	Echinops telfairi	93.85	5.00e-30	124.00
IUUC-Eca-033258	Equus caballus	97.35	4.00e-157	548.00
IUUC-Fca-035980	Felis catus	96.95	8.00e-156	543.00
IUUC-Fal-037554	Ficedula albicollis	60.00	4.00e-59	221.00
IUUC-Fox-037902	Fusarium oxysporum	29.57	2.00e-40	160.00
IUUC-Fso-038418	Fusarium solani	29.57	5.00e-38	152.00
IUUC-Gmo-039288	Gadus morhua	91.73	2.00e-142	499.00
IUUC-Ggr-040076	Gaeumannomyces graminis	30.49	7.00e-39	155.00
IUUC-Gga-041008	Gallus gallus	42.25	2.00e-39	157.00
IUUC-Gac-042347	Gasterosteus aculeatus	90.87	8.00e-148	516.00
IUUC-Gma-043917	Glycine max	44.21	1.00e-59	223.00
IUUC-Ggo-044858	Gorilla gorilla	97.34	2.00e-156	545.00
IUUC-Hsa-046412	Homo sapiens	97.35	6.00e-157	547.00
IUUC-Hvu-047279	Hordeum vulgare	44.44	4.00e-56	211.00
IUUC-Itr-048924	Ictidomys tridecemlineatus	97.32	2.00e-155	542.00
IUUC-Kpa-049117	Komagataella pastoris	28.81	3.00e-27	116.00
IUUC-Lch-049533	Latimeria chalumnae	54.30	7.00e-56	211.00
IUUC-Lpe-051229	Leersia perrieri	32.50	3.00e-22	99.00
IUUC-Loc-052843	Lepisosteus oculatus	91.20	5.00e-118	416.00
IUUC-Lma-052997	Leptosphaeria maculans	34.06	5.00e-51	195.00
IUUC-Laf-053482	Loxodonta africana	97.32	4.00e-155	541.00
IUUC-Mcc-055075	Macaca mulatta	97.35	2.00e-157	548.00
IUUC-Meu-056683	Macropus eugenii	100.00	6.00e-152	530.00
IUUC-Mor-057082	Magnaporthe oryzae	29.03	1.00e-43	171.00
IUUC-Mpo-057573	Magnaporthe poae	30.18	2.00e-40	160.00
IUUC-Mtr-058601	Medicago truncatula	45.59	2.00e-64	239.00
IUUC-Mla-059168	Melampsora laricipopulina	42.31	1.00e-64	241.00
IUUC-Mga-059510	Meleagris gallopavo	97.59	1.00e-45	175.00
IUUC-Mvi-060515	Microbotryum violaceum	40.69	1.00e-52	201.00
IUUC-Mmr-060922	Microcebus murinus	97.34	4.00e-156	544.00
IUUC-Mdo-062491	Monodelphis domestica	99.24	4.00e-152	531.00
IUUC-Mmu-063770	Mus musculus	97.33	5.00e-156	544.00
IUUC-Mac-064789	Musa acuminata	44.76	1.00e-68	253.00
IUUC-Mpu-066107	Mustela putorius furo	97.00	2.00e-158	552.00
IUUC-Mlu-067918	Myotis lucifugus	96.17	7.00e-153	533.00
IUUC-Nfi-068389	Neosartorya fischeri	30.46	2.00e-47	184.00
IUUC-Ncr-068742	Neurospora crassa	31.90	2.00e-45	177.00
IUUC-Nle-069139	Nomascus leucogenys	97.35	6.00e-157	547.00
IUUC-Opr-070898	Ochotona princeps	95.31	5.00e-122	431.00
IUUC-Ont-071991	Oreochromis niloticus	89.66	2.00e-147	515.00
IUUC-Ocu-074065	Oryctolagus cuniculus	96.58	2.00e-155	542.00
IUUC-Oba-075221	Oryza barthii	44.06	7.00e-56	211.00
IUUC-Obr-076914	Oryza brachyantha	42.61	2.00e-58	219.00
IUUC-Ogu-078124	Oryza glumaepatula	44.06	7.00e-56	211.00
IUUC-Oin-080013	Oryza indica	41.92	3.00e-52	199.00
IUUC-Olo-080247	Oryza longistaminata	41.76	8.00e-50	191.00
IUUC-Ome-081769	Oryza meridionalis	44.44	3.00e-58	219.00
IUUC-Oni-082946	Oryza nivara	44.06	8.00e-56	211.00
IUUC-Opu-083268	Oryza punctata	36.40	1.00e-38	154.00
IUUC-Oru-085114	Oryza rufipogon	44.06	7.00e-56	211.00
IUUC-Osa-085829	Oryza sativa	44.83	2.00e-58	219.00
IUUC-Ola-087449	Oryzias latipes	91.19	4.00e-148	518.00
IUUC-Olu-087894	Ostreococcus lucimarinus	43.23	2.00e-59	222.00
IUUC-Oga-089036	Otolemur garnettii	97.32	1.00e-155	543.00
IUUC-Oar-089715	Ovis aries	97.35	4.00e-157	547.00
IUUC-Ptr-091000	Pan troglodytes	97.32	3.00e-155	541.00
IUUC-Pan-092187	Papio anubis	97.35	6.00e-157	547.00
IUUC-Psi-093377	Pelodiscus sinensis	96.21	2.00e-146	512.00
IUUC-Pma-094759	Petromyzon marinus	91.55	8.00e-78	283.00
IUUC-Pno-094883	Phaeosphaeria nodorum	34.50	5.00e-50	192.00
IUUC-Ppa-095684	Physcomitrella patens	46.36	4.00e-61	229.00
IUUC-Pfo-096861	Poecilia formosa	90.87	3.00e-144	505.00
IUUC-Pab-098030	Pongo abelii	97.35	6.00e-157	547.00
IUUC-Pop-099245	Populus trichocarpa	43.36	1.00e-68	253.00
IUUC-Pca-100191	Procavia capensis	92.54	1.00e-148	520.00
IUUC-Ppe-101829	Prunus persica	45.14	8.00e-64	237.00
IUUC-Pva-102689	Pteropus vampyrus	96.97	3.00e-157	548.00
IUUC-Pgr-103286	Puccinia graminis	37.95	2.00e-59	224.00
IUUC-Ptt-103919	Puccinia triticina	36.74	5.00e-59	221.00
IUUC-Pte-104372	Pyrenophora teres	35.28	5.00e-54	205.00
IUUC-Pyt-104456	Pyrenophora triticirepentis	34.67	8.00e-52	198.00
IUUC-Rno-105723	Rattus norvegicus	97.32	2.00e-155	541.00
IUUC-Sce-106348	Saccharomyces cerevisiae	25.38	3.00e-21	96.70
IUUC-Sja-107685	Schizosaccharomyces japonicus	29.08	5.00e-33	135.00
IUUC-Spo-108308	Schizosaccharomyces pombe	28.62	1.00e-33	138.00
IUUC-Ssl-108558	Sclerotinia sclerotiorum	37.25	1.00e-23	105.00
IUUC-Smo-109123	Selaginella moellendorffii	43.93	3.00e-66	245.00
IUUC-Sit-110276	Setaria italica	45.21	1.00e-57	217.00
IUUC-Sly-111819	Solanum lycopersicum	45.21	2.00e-64	239.00
IUUC-Stu-112048	Solanum tuberosum	45.21	2.00e-62	233.00
IUUC-Sbi-114192	Sorghum bicolor	42.86	1.00e-59	223.00
IUUC-Sre-115212	Sporisorium reilianum	38.49	2.00e-55	210.00
IUUC-Ssc-116323	Sus scrofa	97.70	3.00e-156	545.00
IUUC-Tgu-117156	Taeniopygia guttata	94.81	3.00e-39	152.00
IUUC-Tru-118045	Takifugu rubripes	90.80	1.00e-144	506.00
IUUC-Tsy-118823	Tarsius syrichta	80.82	5.00e-114	403.00
IUUC-Tni-120106	Tetraodon nigroviridis	90.51	4.00e-128	451.00
IUUC-Tca-121462	Theobroma cacao	44.44	2.00e-65	243.00
IUUC-Tre-122204	Trichoderma reesei	38.22	7.00e-27	115.00
IUUC-Tvi-122550	Trichoderma virens	29.39	3.00e-41	163.00
IUUC-Tae-124064	Triticum aestivum	43.00	9.00e-60	224.00
IUUC-Tur-126538	Triticum urartu	37.72	1.00e-39	157.00
IUUC-Tme-127197	Tuber melanosporum	42.31	2.00e-59	224.00
IUUC-Tbe-127385	Tupaia belangeri	83.60	1.00e-136	479.00
IUUC-Ttr-128795	Tursiops truncatus	97.34	1.00e-156	546.00
IUUC-Uma-129401	Ustilago maydis	36.05	2.00e-44	174.00
IUUC-Vda-129968	Verticillium dahliae	29.00	2.00e-34	140.00
IUUC-Vvi-130944	Vitis vinifera	44.86	3.00e-65	242.00
IUUC-Xtr-131884	Xenopus tropicalis	93.56	4.00e-148	518.00
IUUC-Xma-133488	Xiphophorus maculatus	90.49	1.00e-144	506.00
IUUC-Yli-134552	Yarrowia lipolytica	25.53	1.00e-27	117.00
IUUC-Zma-135530	Zea mays	42.86	2.00e-59	223.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence