iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066855

Ensembl Protein ID

ENSMPUP00000006180.1

UniProt Accession

M3Y4C9; M3Y4C9_MUSPF

Genbank Protein ID

ENSMPUP00000006180

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01050313

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000006233.1	ENSMPUT00000006288.1	ENSMPUP00000006180.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	91.21	0.00e+00	724.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MDRSKENCIA GPLKATIALG DGPKRVPVTQ QIPPPNPLSA NTGQAQRVLC PSNSSQRIPP 60
QAQKLVSSHK PVQNLKQKQL QATSVPRPVS RPQNNTQKKE QPSSSAPGSN SEKELATKQK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCATCATGGA CAGATCTAAA GAGAATTGCA TTGCGGGGCC TCTGAAGGTA AATTGAATAA 60
TCTGTAATCT CGATCAATTT ATAAAACCCA AGAGGTTGGT TTTATATCTG GAATTCCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR030611--AURKA
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	63.38	5.00e-104	370.00
IUUC-Aml-001426	Ailuropoda melanoleuca	96.38	0.00e+00	774.00
IUUC-Atr-002453	Amborella trichopoda	67.55	1.00e-106	379.00
IUUC-Apl-003626	Anas platyrhynchos	70.95	4.00e-154	537.00
IUUC-Aca-004602	Anolis carolinensis	66.58	7.00e-148	516.00
IUUC-Aly-005878	Arabidopsis lyrata	65.17	2.00e-104	372.00
IUUC-Ath-007117	Arabidopsis thaliana	65.43	3.00e-105	374.00
IUUC-Acl-008199	Aspergillus clavatus	58.98	9.00e-87	313.00
IUUC-Afl-008419	Aspergillus flavus	58.59	3.00e-86	311.00
IUUC-Afu-008751	Aspergillus fumigatus	51.77	8.00e-87	313.00
IUUC-Ani-009181	Aspergillus nidulans	53.22	7.00e-91	327.00
IUUC-Ang-009787	Aspergillus niger	58.98	5.00e-87	314.00
IUUC-Aor-009980	Aspergillus oryzae	58.59	3.00e-86	311.00
IUUC-Ate-010286	Aspergillus terreus	51.78	1.00e-86	313.00
IUUC-Ame-010849	Astyanax mexicanus	58.50	9.00e-129	453.00
IUUC-Bgr-012110	Blumeria graminis	60.46	1.00e-87	316.00
IUUC-Bta-013474	Bos taurus	89.15	0.00e+00	716.00
IUUC-Bci-013756	Botrytis cinerea	53.89	6.00e-95	340.00
IUUC-Bdi-014257	Brachypodium distachyon	64.08	2.00e-105	374.00
IUUC-Bol-016310	Brassica oleracea	62.41	2.00e-102	365.00
IUUC-Bra-017438	Brassica rapa	63.97	4.00e-104	370.00
IUUC-Cel-018157	Caenorhabditis elegans	63.85	1.00e-101	362.00
IUUC-Cja-019282	Callithrix jacchus	89.15	0.00e+00	691.00
IUUC-Cfa-020162	Canis familiaris	94.32	0.00e+00	764.00
IUUC-Cpo-021764	Cavia porcellus	82.78	0.00e+00	642.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	67.42	2.00e-106	378.00
IUUC-Csa-023694	Chlorocebus sabaeus	88.89	0.00e+00	645.00
IUUC-Cho-024350	Choloepus hoffmanni	96.94	5.00e-113	399.00
IUUC-Cin-025542	Ciona intestinalis	73.75	5.00e-117	413.00
IUUC-Csv-025873	Ciona savignyi	68.88	5.00e-118	417.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	50.96	4.00e-81	295.00
IUUC-Cne-026928	Cryptococcus neoformans	61.87	4.00e-95	341.00
IUUC-Cme-027336	Cyanidioschyzon merolae	69.72	4.00e-118	418.00
IUUC-Dre-028198	Danio rerio	62.30	6.00e-131	460.00
IUUC-Dno-029928	Dasypus novemcinctus	87.34	0.00e+00	655.00
IUUC-Dor-030238	Dipodomys ordii	78.81	1.00e-178	619.00
IUUC-Dse-031266	Dothistroma septosporum	56.12	9.00e-93	333.00
IUUC-Dme-032007	Drosophila melanogaster	61.69	8.00e-100	357.00
IUUC-Ete-032911	Echinops telfairi	69.03	2.00e-137	481.00
IUUC-Eca-033749	Equus caballus	92.51	0.00e+00	741.00
IUUC-Eeu-035170	Erinaceus europaeus	88.66	0.00e+00	703.00
IUUC-Fca-035498	Felis catus	94.64	0.00e+00	729.00
IUUC-Fal-037397	Ficedula albicollis	67.32	8.00e-149	520.00
IUUC-Fox-037747	Fusarium oxysporum	54.02	3.00e-91	328.00
IUUC-Fso-038429	Fusarium solani	55.44	6.00e-90	324.00
IUUC-Gmo-039378	Gadus morhua	59.44	1.00e-125	442.00
IUUC-Ggr-039939	Gaeumannomyces graminis	60.66	1.00e-94	339.00
IUUC-Gga-040187	Gallus gallus	71.57	2.00e-153	535.00
IUUC-Gac-042223	Gasterosteus aculeatus	61.70	6.00e-132	463.00
IUUC-Gma-042870	Glycine max	66.17	2.00e-98	351.00
IUUC-Ggo-045617	Gorilla gorilla	90.44	0.00e+00	721.00
IUUC-Hsa-046968	Homo sapiens	91.21	0.00e+00	724.00
IUUC-Hvu-047072	Hordeum vulgare	55.17	1.00e-80	292.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	75.97	2.00e-170	591.00
IUUC-Kpa-049093	Komagataella pastoris	56.70	7.00e-78	283.00
IUUC-Lch-050346	Latimeria chalumnae	67.59	3.00e-148	518.00
IUUC-Lpe-051466	Leersia perrieri	66.91	2.00e-105	374.00
IUUC-Lma-053006	Leptosphaeria maculans	58.94	3.00e-89	322.00
IUUC-Laf-053422	Loxodonta africana	88.11	0.00e+00	698.00
IUUC-Mcc-055245	Macaca mulatta	89.15	0.00e+00	645.00
IUUC-Mor-056952	Magnaporthe oryzae	58.94	6.00e-91	327.00
IUUC-Mpo-057605	Magnaporthe poae	59.85	2.00e-95	342.00
IUUC-Mtr-057726	Medicago truncatula	66.29	1.00e-104	372.00
IUUC-Mla-059174	Melampsora laricipopulina	63.46	4.00e-99	355.00
IUUC-Mga-059562	Meleagris gallopavo	60.86	6.00e-117	414.00
IUUC-Mvi-060305	Microbotryum violaceum	61.74	5.00e-94	338.00
IUUC-Mmr-061588	Microcebus murinus	88.34	0.00e+00	713.00
IUUC-Mdo-061914	Monodelphis domestica	78.87	1.00e-177	615.00
IUUC-Mmu-063288	Mus musculus	82.69	0.00e+00	641.00
IUUC-Mac-064969	Musa acuminata	64.44	6.00e-106	377.00
IUUC-Mlu-068046	Myotis lucifugus	88.89	0.00e+00	708.00
IUUC-Nfi-068527	Neosartorya fischeri	59.38	1.00e-86	313.00
IUUC-Ncr-068678	Neurospora crassa	60.61	1.00e-92	333.00
IUUC-Nle-069848	Nomascus leucogenys	90.18	0.00e+00	718.00
IUUC-Opr-070589	Ochotona princeps	82.12	0.00e+00	628.00
IUUC-Ont-071733	Oreochromis niloticus	63.24	2.00e-126	445.00
IUUC-Oan-073399	Ornithorhynchus anatinus	85.57	4.00e-150	523.00
IUUC-Ocu-074063	Oryctolagus cuniculus	86.79	0.00e+00	696.00
IUUC-Oba-075264	Oryza barthii	64.18	9.00e-105	372.00
IUUC-Obr-076048	Oryza brachyantha	66.04	6.00e-104	370.00
IUUC-Ogl-077637	Oryza glaberrima	66.92	8.00e-104	369.00
IUUC-Ogu-078830	Oryza glumaepatula	64.18	5.00e-105	374.00
IUUC-Oin-079150	Oryza indica	64.18	4.00e-105	374.00
IUUC-Olo-080398	Oryza longistaminata	57.68	3.00e-82	298.00
IUUC-Ome-081544	Oryza meridionalis	55.47	8.00e-90	323.00
IUUC-Oni-082250	Oryza nivara	64.18	4.00e-105	374.00
IUUC-Opu-083638	Oryza punctata	64.44	5.00e-105	374.00
IUUC-Oru-084981	Oryza rufipogon	64.18	4.00e-105	374.00
IUUC-Osa-085961	Oryza sativa	64.18	4.00e-105	374.00
IUUC-Olu-087880	Ostreococcus lucimarinus	70.11	6.00e-111	393.00
IUUC-Oga-088891	Otolemur garnettii	87.05	0.00e+00	694.00
IUUC-Oar-090021	Ovis aries	88.63	0.00e+00	690.00
IUUC-Ptr-091458	Pan troglodytes	90.96	0.00e+00	723.00
IUUC-Pan-092546	Papio anubis	88.63	0.00e+00	643.00
IUUC-Psi-093280	Pelodiscus sinensis	74.33	2.00e-163	568.00
IUUC-Pma-094298	Petromyzon marinus	77.86	2.00e-120	424.00
IUUC-Pno-094847	Phaeosphaeria nodorum	59.40	4.00e-89	321.00
IUUC-Ppa-095855	Physcomitrella patens	63.48	4.00e-108	384.00
IUUC-Pfo-096428	Poecilia formosa	62.15	3.00e-130	458.00
IUUC-Pab-098696	Pongo abelii	89.43	0.00e+00	699.00
IUUC-Pop-099405	Populus trichocarpa	64.62	4.00e-105	374.00
IUUC-Pca-100740	Procavia capensis	81.91	0.00e+00	654.00
IUUC-Ppe-101854	Prunus persica	63.16	1.00e-105	375.00
IUUC-Pva-103212	Pteropus vampyrus	89.66	0.00e+00	715.00
IUUC-Pgr-103474	Puccinia graminis	63.64	4.00e-99	354.00
IUUC-Ptt-103933	Puccinia triticina	49.62	1.00e-62	233.00
IUUC-Pte-104089	Pyrenophora teres	49.44	6.00e-90	324.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	49.44	5.00e-90	324.00
IUUC-Rno-105057	Rattus norvegicus	83.46	0.00e+00	649.00
IUUC-Sha-107137	Sarcophilus harrisii	80.88	0.00e+00	633.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	54.55	1.00e-98	353.00
IUUC-Spo-108078	Schizosaccharomyces pombe	63.85	8.00e-103	366.00
IUUC-Smo-109288	Selaginella moellendorffii	67.17	1.00e-106	379.00
IUUC-Sit-110246	Setaria italica	64.71	3.00e-104	371.00
IUUC-Sly-111379	Solanum lycopersicum	65.57	4.00e-106	377.00
IUUC-Stu-112777	Solanum tuberosum	62.24	1.00e-105	375.00
IUUC-Sbi-114325	Sorghum bicolor	63.97	7.00e-104	369.00
IUUC-Sre-115203	Sporisorium reilianum	59.55	4.00e-81	295.00
IUUC-Ssc-115361	Sus scrofa	89.92	0.00e+00	717.00
IUUC-Tgu-116967	Taeniopygia guttata	72.19	3.00e-149	520.00
IUUC-Tru-117570	Takifugu rubripes	62.53	4.00e-136	478.00
IUUC-Tsy-119280	Tarsius syrichta	65.12	2.00e-131	462.00
IUUC-Tni-120721	Tetraodon nigroviridis	64.27	2.00e-134	471.00
IUUC-Tca-121494	Theobroma cacao	64.39	3.00e-104	371.00
IUUC-Tre-121869	Trichoderma reesei	56.96	6.00e-93	334.00
IUUC-Tvi-122510	Trichoderma virens	61.36	7.00e-92	330.00
IUUC-Tae-123071	Triticum aestivum	63.38	5.00e-104	370.00
IUUC-Tur-126240	Triticum urartu	63.38	2.00e-103	368.00
IUUC-Tme-126921	Tuber melanosporum	58.82	3.00e-96	345.00
IUUC-Tbe-127872	Tupaia belangeri	82.40	1.00e-178	619.00
IUUC-Ttr-129134	Tursiops truncatus	89.41	0.00e+00	691.00
IUUC-Uma-129412	Ustilago maydis	58.43	7.00e-80	291.00
IUUC-Vda-130003	Verticillium dahliae	50.85	3.00e-93	335.00
IUUC-Vvi-131272	Vitis vinifera	61.90	4.00e-105	374.00
IUUC-Xtr-132019	Xenopus tropicalis	66.17	1.00e-150	526.00
IUUC-Xma-134203	Xiphophorus maculatus	61.98	5.00e-134	470.00
IUUC-Yli-134503	Yarrowia lipolytica	49.18	1.00e-86	313.00
IUUC-Zma-135232	Zea mays	64.34	3.00e-104	371.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence