iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000012291.4	ENSPTRT00000075372.1	ENSPTRP00000061326.1
ENSPTRG00000012291.4	ENSPTRT00000022817.3	ENSPTRP00000021055.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.50e-07	30.3	269	310

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C e f  kd  ++lpC+H+fh++C+  w         + +CP C+
   Q: 269  CAVCIENFkvKDIIRILPCKHIFHRTCIDPW------LLDHRTCPMCK 310
           ********8866699****************......9999******6 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MAWRRREAGV GARGVLALAL LALALCVPGA RGRALEWFSA VVNIEYVDPQ TNLTVWSVSE 60
SGRFGDSSPK EGAHGLVGVP WAPGGDLEGC APDTRFFVPE PGGRGAAPWV ALVARGGCTF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCTTCCTG GGCGGCGGTG GGTGTCCGCT TCTCTCTGCT CTTTGACTGC ACCGCACTCG 60
CGCGTGACCC TGACTCCCCC TAGTCAGCTC AGCGGTGCTG CCATGGCGTG GCGGCGGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0035690--P:cellular response to drug
GO:0043409--P:negative regulation of MAPK cascade
GO:0031647--P:regulation of protein stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001968	Ailuropoda melanoleuca	83.87	1.00e-177	615.00
IUUC-Apl-004109	Anas platyrhynchos	71.91	5.00e-105	373.00
IUUC-Bta-012340	Bos taurus	81.54	4.00e-171	593.00
IUUC-Cja-019566	Callithrix jacchus	91.25	0.00e+00	680.00
IUUC-Cfa-020289	Canis familiaris	84.94	6.00e-113	399.00
IUUC-Cpo-021916	Cavia porcellus	67.05	9.00e-74	269.00
IUUC-Csa-024084	Chlorocebus sabaeus	96.00	0.00e+00	684.00
IUUC-Cho-024305	Choloepus hoffmanni	82.58	2.00e-138	484.00
IUUC-Cgl-026578	Colletotrichum gloeosporioides	48.08	2.00e-12	67.00
IUUC-Cne-026985	Cryptococcus neoformans	29.91	2.00e-11	64.70
IUUC-Cme-027122	Cyanidioschyzon merolae	37.97	5.00e-12	66.20
IUUC-Dno-030098	Dasypus novemcinctus	82.75	0.00e+00	648.00
IUUC-Dor-030620	Dipodomys ordii	74.42	2.00e-144	504.00
IUUC-Ete-032306	Echinops telfairi	83.19	4.00e-175	607.00
IUUC-Fca-035950	Felis catus	82.11	6.00e-121	426.00
IUUC-Fal-037429	Ficedula albicollis	68.01	1.00e-139	489.00
IUUC-Fso-038141	Fusarium solani	41.25	2.00e-15	77.40
IUUC-Gga-041201	Gallus gallus	66.49	3.00e-135	474.00
IUUC-Ggo-045429	Gorilla gorilla	98.61	0.00e+00	686.00
IUUC-Hsa-046191	Homo sapiens	99.00	0.00e+00	734.00
IUUC-Itr-048018	Ictidomys tridecemlineatus	81.18	3.00e-160	557.00
IUUC-Lch-049498	Latimeria chalumnae	61.89	8.00e-133	466.00
IUUC-Laf-054239	Loxodonta africana	69.69	3.00e-136	477.00
IUUC-Meu-056382	Macropus eugenii	74.17	5.00e-156	543.00
IUUC-Mor-056917	Magnaporthe oryzae	43.94	5.00e-13	68.90
IUUC-Mga-059435	Meleagris gallopavo	69.31	2.00e-69	254.00
IUUC-Mmr-061513	Microcebus murinus	85.48	9.00e-176	609.00
IUUC-Mdo-063028	Monodelphis domestica	74.59	1.00e-159	556.00
IUUC-Mmu-063545	Mus musculus	77.01	2.00e-153	535.00
IUUC-Mpu-066370	Mustela putorius furo	84.05	1.00e-170	592.00
IUUC-Mlu-067271	Myotis lucifugus	76.11	7.00e-138	483.00
IUUC-Nle-069207	Nomascus leucogenys	98.00	0.00e+00	714.00
IUUC-Opr-070704	Ochotona princeps	70.85	1.00e-96	345.00
IUUC-Oan-072837	Ornithorhynchus anatinus	69.84	4.00e-145	507.00
IUUC-Ocu-074671	Oryctolagus cuniculus	79.72	2.00e-121	428.00
IUUC-Oga-089083	Otolemur garnettii	83.00	0.00e+00	626.00
IUUC-Oar-089254	Ovis aries	81.22	3.00e-115	407.00
IUUC-Pan-092636	Papio anubis	95.62	0.00e+00	678.00
IUUC-Psi-093435	Pelodiscus sinensis	75.31	2.00e-99	355.00
IUUC-Pab-098525	Pongo abelii	98.45	0.00e+00	697.00
IUUC-Pva-102395	Pteropus vampyrus	80.82	3.00e-175	607.00
IUUC-Pgr-103263	Puccinia graminis	43.84	7.00e-12	66.20
IUUC-Rno-105789	Rattus norvegicus	77.47	5.00e-151	527.00
IUUC-Sha-107305	Sarcophilus harrisii	71.85	2.00e-97	347.00
IUUC-Ssc-115598	Sus scrofa	82.93	8.00e-169	586.00
IUUC-Tgu-116463	Taeniopygia guttata	68.61	1.00e-135	476.00
IUUC-Tsy-118915	Tarsius syrichta	86.99	8.00e-111	392.00
IUUC-Tre-121978	Trichoderma reesei	51.02	7.00e-13	68.60
IUUC-Tme-126970	Tuber melanosporum	49.06	1.00e-12	68.20
IUUC-Tbe-127906	Tupaia belangeri	64.90	2.00e-83	301.00
IUUC-Xtr-131821	Xenopus tropicalis	61.93	1.00e-128	452.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence