iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093785

Ensembl Protein ID

ENSPSIP00000016744.1

UniProt Accession

K7G8Y3; K7G8Y3_PELSI

Genbank Protein ID

ENSPSIP00000016744

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01069673

Gene Name

HCLS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000014923.1	ENSPSIT00000016820.1	ENSPSIP00000016744.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.80e-13	48.6	477	528

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
            +lydy+++ dde ++   d+++ i  e  degW++g  + +g+ GlfP+n+v+ l
   Q: 477  VALYDYQGEGDDEISFDPNDTITNI--EMVDEGWWRG--HCHGRAGLFPANYVKLL 528
           68***********************..9*********..9*************977 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MWKAAVGHNV AVKVESQGDD WDTDPDFVND ISEKDQRWGA KTIEGSGRAE HINIHQLRSK 60
VSEEHEVIKQ KELASGPKAS YGYGGKFGKE KDRMDKSALG HEYVADVEKH SSQTDAAKGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAATAACTT CGCTGTGTAG ACATACCCTG AGAGAATATA GGGTTGAGTC TGTGGCTCCA 60
GAATGCTTTG TGTGTCACGG TGTCTTCCTG GAGTCTCTGT CTGTGACACT GACTTACTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028534--HS1
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005667--C:transcription factor complex
GO:0030041--P:actin filament polymerization
GO:0071345--P:cellular response to cytokine stimulus
GO:0030218--P:erythrocyte differentiation
GO:2000107--P:negative regulation of leukocyte apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0008284--P:positive regulation of cell proliferation
GO:0030854--P:positive regulation of granulocyte differentiation
GO:0045651--P:positive regulation of macrophage differentiation
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0042531--P:positive regulation of tyrosine phosphorylation of STAT protein
GO:0030833--P:regulation of actin filament polymerization
GO:0009725--P:response to hormone

KEGG

pss:102454370

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001194	Ailuropoda melanoleuca	51.20	1.00e-133	469.00
IUUC-Apl-004103	Anas platyrhynchos	51.48	1.00e-147	516.00
IUUC-Ame-011504	Astyanax mexicanus	51.04	4.00e-125	441.00
IUUC-Bta-012591	Bos taurus	55.73	2.00e-114	405.00
IUUC-Cja-019982	Callithrix jacchus	68.88	4.00e-112	397.00
IUUC-Cfa-020262	Canis familiaris	69.15	1.00e-113	402.00
IUUC-Cpo-021362	Cavia porcellus	70.32	4.00e-114	404.00
IUUC-Csa-023911	Chlorocebus sabaeus	57.61	2.00e-115	409.00
IUUC-Cgl-026571	Colletotrichum gloeosporioides	54.17	1.00e-10	61.60
IUUC-Dor-030437	Dipodomys ordii	51.93	7.00e-90	323.00
IUUC-Dme-031931	Drosophila melanogaster	49.83	1.00e-75	276.00
IUUC-Ete-033160	Echinops telfairi	44.95	4.00e-101	361.00
IUUC-Eca-033269	Equus caballus	51.52	5.00e-134	470.00
IUUC-Eeu-035032	Erinaceus europaeus	41.87	6.00e-67	248.00
IUUC-Fca-035999	Felis catus	51.24	5.00e-139	487.00
IUUC-Fal-037107	Ficedula albicollis	64.42	1.00e-173	602.00
IUUC-Fox-037778	Fusarium oxysporum	61.40	1.00e-15	78.60
IUUC-Fso-038435	Fusarium solani	58.82	5.00e-13	69.70
IUUC-Gga-040335	Gallus gallus	67.60	0.00e+00	631.00
IUUC-Ggo-044505	Gorilla gorilla	57.58	2.00e-115	409.00
IUUC-Hsa-046728	Homo sapiens	57.58	3.00e-115	408.00
IUUC-Lch-050221	Latimeria chalumnae	73.55	8.00e-119	420.00
IUUC-Lma-053035	Leptosphaeria maculans	59.18	5.00e-13	69.70
IUUC-Laf-054202	Loxodonta africana	70.00	9.00e-113	400.00
IUUC-Mcc-055824	Macaca mulatta	57.36	2.00e-115	409.00
IUUC-Mor-057105	Magnaporthe oryzae	52.94	9.00e-12	65.50
IUUC-Mpo-057325	Magnaporthe poae	51.02	2.00e-10	58.50
IUUC-Mdo-062515	Monodelphis domestica	53.56	2.00e-129	455.00
IUUC-Mmu-064341	Mus musculus	53.61	9.00e-137	479.00
IUUC-Mpu-066565	Mustela putorius furo	69.86	2.00e-113	402.00
IUUC-Mlu-066942	Myotis lucifugus	69.86	2.00e-113	402.00
IUUC-Nle-069436	Nomascus leucogenys	57.87	2.00e-116	412.00
IUUC-Opr-070288	Ochotona princeps	50.37	1.00e-112	400.00
IUUC-Ont-071712	Oreochromis niloticus	62.65	1.00e-114	406.00
IUUC-Ocu-074686	Oryctolagus cuniculus	71.07	5.00e-114	404.00
IUUC-Ola-086894	Oryzias latipes	65.73	4.00e-102	364.00
IUUC-Oga-088585	Otolemur garnettii	49.28	2.00e-129	455.00
IUUC-Oar-089686	Ovis aries	52.65	4.00e-141	494.00
IUUC-Ptr-090461	Pan troglodytes	58.10	7.00e-116	410.00
IUUC-Pan-091887	Papio anubis	57.61	1.00e-115	409.00
IUUC-Pno-095096	Phaeosphaeria nodorum	57.14	2.00e-14	74.30
IUUC-Pab-098222	Pongo abelii	57.33	7.00e-115	407.00
IUUC-Pca-100668	Procavia capensis	51.10	5.00e-133	467.00
IUUC-Pva-102767	Pteropus vampyrus	56.79	3.00e-87	315.00
IUUC-Pgr-103652	Puccinia graminis	51.72	6.00e-11	62.40
IUUC-Rno-106001	Rattus norvegicus	53.89	6.00e-139	487.00
IUUC-Sce-106228	Saccharomyces cerevisiae	52.38	9.00e-08	51.60
IUUC-Sha-106912	Sarcophilus harrisii	53.82	4.00e-154	537.00
IUUC-Sja-107956	Schizosaccharomyces japonicus	49.15	9.00e-15	75.50
IUUC-Sar-113338	Sorex araneus	50.00	5.00e-116	410.00
IUUC-Ssc-116027	Sus scrofa	51.51	4.00e-137	481.00
IUUC-Tgu-117472	Taeniopygia guttata	57.82	3.00e-162	564.00
IUUC-Tni-119931	Tetraodon nigroviridis	68.18	2.00e-116	412.00
IUUC-Tre-122167	Trichoderma reesei	61.22	3.00e-13	70.10
IUUC-Tvi-122614	Trichoderma virens	61.22	3.00e-13	70.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence