iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nfi-068557

Ensembl Protein ID

CADNFIAP00005946

UniProt Accession

A1D6Q5; A1D6Q5_NEOFI

Genbank Protein ID

EAW21399.1

Protein Name

Ubiquitin C-terminal hydrolase, putative

Genbank Nucleotide ID

DS027690

Gene Name

NFIA_065630

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADNFIAG00006103	CADNFIAT00006103	CADNFIAP00005946

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.30e-49	167.5	47	641

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle..........kkkeklneenp....................kepkgellkslqklfeelw.. 61
           +Gl+N  N C++NS+LQ+L+ + +lr +l +                                         + ++g+++++l++++  l   
   Q: 47   VGLSNPANDCFINSILQALAGLGDLRVYLIRelhrreldgpD---------VynslpeadetprgmrpervrELQQGTITRALKEMLDRLNer 130
           6******************************74444444441.........25555555556666666666666778*************977 PP
   S: 62   kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk...................eknkpkeeeeeedkselsde...... 129
              kk ++ r++++al+ + +   + +qqDaqEfl+++ ++l +e +                                       e      
   Q: 131  PIYKKTITNRAFIQALEYAFRTRISRNQQDAQEFLQIVAERLCDEYHAglkarqraqgllatlpgsgG------------------Eesvqss 205
           7778999**********99999889******************9996656556555555554444430..................0333444 PP
   S: 130  .......................aeekkkkknkslisdlFqgqlksqikclecdnvs.sreepfldlslpvpgkeetkkeslqdcLesftkee 198
                                    ++k k+ ++     F+gq++sqi c+ c+ ++   + +f+ l+l+vp+k++t   +l++c++   k+e
   Q: 206  avekgsteievriddgtemglpaIIDNKLKEIDNEYGFPFEGQMESQIECQFCHYQYkPNKTSFVNLTLQVPQKSST---TLSSCFDGLLKTE 295
           555555666677778999999997888999999999********************989999*************99...************* PP
   S: 199  elegenkyycekck......................................................kkqeaekklklkklPevLilhLkRf 237
            +++   + c++c+                                                       k++  + ++++ +P+++ +hL+R 
   Q: 296  YIDD---FRCDRCRlqhaldakmvemsrshstrdrerleqdiqlirhtiatdpenppegvslppsdlaPKRKIARHMRITVFPKIIAIHLSRS 385
           **97...*******99********999999999999999999999999999999999999999999998888********************* PP
   S: 238  sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn............................. 301
            f++  +s++k+  kv+fp++L l   +++        k ++L+a+v+H+Gs++sGHY ++ +n                             
   Q: 386  IFDR--SSSTKNAAKVSFPERLPLGGILSQ--------KWFKLLAIVCHKGSHNSGHYESFRRNnlyppfstpdvfssyaqsratsvnpstap 468
           9988..5889***************88888........78***************************************************** PP
   S: 302  ............................................................................................. 301
                                                                                                        
   Q: 469  sprlaargvpetepspislssstslpslsgtslssparsqsvsardssqpasqlnappspsarpttsssrvsfqsirtkssgskqnlsppgse 561
           ********************************************************************************************* PP
   S: 302  ..............................................ekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
                                                         ++++W++++D+k++e+k ++vl ++ ++ Y+lfY+
   Q: 562  tqspasdsgawsksgsrpsfmserttprtppeapalsssrlrrrkkTNDRWWRISDEKIKECKTSDVLGMQ-KEVYLLFYE 641
           ***************************99999999999999987655666*******************65.9*******8 PP

Organism

Neosartorya fischeri

Protein Sequence
(Fasta)

MQEKSTTIAA YAAGASLAAV ALFYVFGPNY TIDGDDSNDS NRKKSIVGLS NPANDCFINS 60
ILQALAGLGD LRVYLIRELH RRELDGPDVY NSLPEADETP RGMRPERVRE LQQGTITRAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGGAAA AGTCGACGAC CATCGCCGCA TACGCAGCCG GAGCATCCCT CGCCGCTGTG 60
GCCCTCTTCT ACGTCTTCGG ACCAAATTAC ACAATTGACG GCGACGACTC GAACGACAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

nfi:NFIA_065630

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007955	Ashbya gossypii	25.60	4.00e-21	94.70
IUUC-Acl-008228	Aspergillus clavatus	83.59	0.00e+00	932.00
IUUC-Afl-008530	Aspergillus flavus	80.08	0.00e+00	775.00
IUUC-Afu-008943	Aspergillus fumigatus	96.45	0.00e+00	1160.00
IUUC-Ang-009829	Aspergillus niger	70.32	0.00e+00	823.00
IUUC-Aor-009934	Aspergillus oryzae	80.93	0.00e+00	742.00
IUUC-Ate-010439	Aspergillus terreus	72.71	0.00e+00	832.00
IUUC-Bgr-012072	Blumeria graminis	47.73	1.00e-95	342.00
IUUC-Bci-013641	Botrytis cinerea	51.79	3.00e-129	453.00
IUUC-Cgl-026463	Colletotrichum gloeosporioides	51.03	4.00e-119	420.00
IUUC-Dse-031517	Dothistroma septosporum	51.16	4.00e-115	407.00
IUUC-Fox-037837	Fusarium oxysporum	45.20	2.00e-145	507.00
IUUC-Fso-038234	Fusarium solani	45.50	2.00e-141	494.00
IUUC-Ggr-039945	Gaeumannomyces graminis	58.71	1.00e-71	262.00
IUUC-Lma-053197	Leptosphaeria maculans	76.19	4.00e-16	77.80
IUUC-Mor-057061	Magnaporthe oryzae	50.81	2.00e-124	437.00
IUUC-Mpo-057549	Magnaporthe poae	56.72	4.00e-69	254.00
IUUC-Ncr-068961	Neurospora crassa	49.28	3.00e-111	393.00
IUUC-Obr-076005	Oryza brachyantha	24.87	5.00e-12	64.30
IUUC-Oin-080096	Oryza indica	27.57	2.00e-09	55.10
IUUC-Olo-080702	Oryza longistaminata	28.99	5.00e-07	48.50
IUUC-Pno-094802	Phaeosphaeria nodorum	58.08	1.00e-137	481.00
IUUC-Pte-104416	Pyrenophora teres	57.17	7.00e-138	482.00
IUUC-Pyt-104503	Pyrenophora triticirepentis	51.08	9.00e-155	538.00
IUUC-Sce-106365	Saccharomyces cerevisiae	26.73	2.00e-21	95.50
IUUC-Tre-121937	Trichoderma reesei	48.81	8.00e-116	409.00
IUUC-Tvi-122428	Trichoderma virens	48.89	1.00e-115	408.00
IUUC-Tme-126993	Tuber melanosporum	47.65	3.00e-99	354.00
IUUC-Vda-129757	Verticillium dahliae	47.49	1.00e-116	412.00
IUUC-Yli-134426	Yarrowia lipolytica	31.66	3.00e-39	155.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence