iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000137942.16	ENST00000604705.5	ENSP00000473921.1
ENSG00000137942.16	ENST00000370253.6	ENSP00000359275.2
ENSG00000137942.16	ENST00000424449.2	ENSP00000397451.2
ENSG00000137942.16	ENST00000271234.11	ENSP00000271234.7
ENSG00000137942.16	ENST00000260506.12	ENSP00000260506.8

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
UTRdb	AREsite	circBase	circRNADb
CircNet	miRTarBase	microRNA	TRANSFAC
RepTar	SomamiR	miRcode	RAID2
Protein-protein Interaction
HINT	InWeb_IM
Disease-associated Variation
GWASdb	GWAS Central	OMIM
Post-translational Modifications (PTMs)
PHOSIDA	BioGRID	mUbiSiDa
DNA Methylation
MethyCancer	TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.80e-10	40.9	543	595

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           ++++y++++ n+++L +k+G+v+++i +e++  gW ++ +  +g +G +P  ++ 
   Q: 543  CKAIYPFDGHNEGTLAMKEGEVLYII-EEDKGDGWTRA-RRQNGEEGYVPTSYID 595
           99************************.999999*****.59***********996 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MSWGTELWDQ FDSLDKHTQW GIDFLERYAK FVKERIEIEQ NYAKQLRNLV KKYCPKRSSK 60
DEEPRFTSCV AFFNILNELN DYAGQREVVA EEMAHRVYGE LMRYAHDLKT ERKMHLQEGR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCACTCACTG GGGAGCCCGG CGGTGGCGGC ACCTTTCGAG GTAGACCCGC TGAGCTGCTA 60
GCCCGCCGGC CAGCGAGTGA GAGGTCGGAC AGACTGTGGA GCCGACAGAC TGAAGGACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR031160--F_BAR
IPR001060--FCH_dom
IPR030116--FNBP1L
IPR011072--HR1_rho-bd
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF00018--SH3_1

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0006897--P:endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002284	Ailuropoda melanoleuca	98.68	0.00e+00	1191.00
IUUC-Apl-003448	Anas platyrhynchos	92.23	0.00e+00	1117.00
IUUC-Acl-008089	Aspergillus clavatus	24.02	1.00e-13	71.60
IUUC-Afl-008472	Aspergillus flavus	23.77	1.00e-11	65.50
IUUC-Afu-009118	Aspergillus fumigatus	24.43	9.00e-16	79.00
IUUC-Ang-009697	Aspergillus niger	22.61	6.00e-11	63.20
IUUC-Aor-010089	Aspergillus oryzae	24.05	5.00e-13	70.10
IUUC-Ate-010418	Aspergillus terreus	22.65	5.00e-11	63.20
IUUC-Bgr-012268	Blumeria graminis	24.11	3.00e-14	73.90
IUUC-Bta-013289	Bos taurus	84.77	0.00e+00	1005.00
IUUC-Bci-013658	Botrytis cinerea	26.55	1.00e-08	55.50
IUUC-Cja-019157	Callithrix jacchus	98.66	0.00e+00	1173.00
IUUC-Cfa-021263	Canis familiaris	98.67	0.00e+00	1174.00
IUUC-Cpo-022162	Cavia porcellus	98.17	0.00e+00	1164.00
IUUC-Csa-024094	Chlorocebus sabaeus	75.37	0.00e+00	867.00
IUUC-Cho-024432	Choloepus hoffmanni	85.06	0.00e+00	1030.00
IUUC-Dno-030053	Dasypus novemcinctus	74.88	0.00e+00	847.00
IUUC-Dor-030954	Dipodomys ordii	89.68	0.00e+00	1051.00
IUUC-Dse-031554	Dothistroma septosporum	23.91	1.00e-07	52.00
IUUC-Ete-033202	Echinops telfairi	82.10	0.00e+00	984.00
IUUC-Eca-034433	Equus caballus	98.34	0.00e+00	1174.00
IUUC-Fca-036316	Felis catus	98.84	0.00e+00	1190.00
IUUC-Fal-037482	Ficedula albicollis	68.07	0.00e+00	671.00
IUUC-Fox-037938	Fusarium oxysporum	24.56	1.00e-14	75.10
IUUC-Fso-038099	Fusarium solani	24.85	1.00e-14	75.10
IUUC-Ggr-040011	Gaeumannomyces graminis	23.77	5.00e-11	63.20
IUUC-Gga-040893	Gallus gallus	71.55	0.00e+00	806.00
IUUC-Ggo-045368	Gorilla gorilla	99.01	0.00e+00	1194.00
IUUC-Itr-048450	Ictidomys tridecemlineatus	98.51	0.00e+00	907.00
IUUC-Lch-049559	Latimeria chalumnae	78.31	0.00e+00	644.00
IUUC-Laf-053633	Loxodonta africana	98.02	0.00e+00	1179.00
IUUC-Mcc-055726	Macaca mulatta	99.84	0.00e+00	1216.00
IUUC-Mor-057091	Magnaporthe oryzae	25.00	4.00e-10	60.10
IUUC-Mpo-057513	Magnaporthe poae	23.36	2.00e-10	61.60
IUUC-Mla-059151	Melampsora laricipopulina	22.43	1.00e-10	62.00
IUUC-Mga-059482	Meleagris gallopavo	70.26	0.00e+00	784.00
IUUC-Mmr-061011	Microcebus murinus	99.34	0.00e+00	1211.00
IUUC-Mdo-062199	Monodelphis domestica	97.51	0.00e+00	1179.00
IUUC-Mmu-064089	Mus musculus	97.87	0.00e+00	1197.00
IUUC-Mpu-065924	Mustela putorius furo	74.88	0.00e+00	863.00
IUUC-Mlu-068188	Myotis lucifugus	93.55	0.00e+00	1112.00
IUUC-Nfi-068456	Neosartorya fischeri	24.43	6.00e-16	79.70
IUUC-Ncr-068849	Neurospora crassa	22.82	2.00e-10	61.60
IUUC-Nle-070050	Nomascus leucogenys	99.16	0.00e+00	1182.00
IUUC-Opr-071010	Ochotona princeps	81.68	6.00e-120	424.00
IUUC-Oan-073051	Ornithorhynchus anatinus	93.89	0.00e+00	1124.00
IUUC-Ocu-074906	Oryctolagus cuniculus	98.68	0.00e+00	1197.00
IUUC-Oga-088792	Otolemur garnettii	97.69	0.00e+00	1171.00
IUUC-Oar-090267	Ovis aries	97.52	0.00e+00	1171.00
IUUC-Ptr-091071	Pan troglodytes	99.83	0.00e+00	1209.00
IUUC-Pan-092738	Papio anubis	75.04	0.00e+00	850.00
IUUC-Psi-093274	Pelodiscus sinensis	72.83	0.00e+00	821.00
IUUC-Pab-098294	Pongo abelii	99.67	0.00e+00	1207.00
IUUC-Pyt-104583	Pyrenophora triticirepentis	24.24	4.00e-08	53.90
IUUC-Rno-105487	Rattus norvegicus	97.52	0.00e+00	1222.00
IUUC-Sha-107064	Sarcophilus harrisii	95.91	0.00e+00	1105.00
IUUC-Ssl-108508	Sclerotinia sclerotiorum	24.45	5.00e-09	56.60
IUUC-Ssc-116115	Sus scrofa	96.90	0.00e+00	1171.00
IUUC-Tgu-117005	Taeniopygia guttata	92.31	0.00e+00	1105.00
IUUC-Tsy-119510	Tarsius syrichta	89.50	0.00e+00	969.00
IUUC-Tre-122218	Trichoderma reesei	24.48	9.00e-12	65.90
IUUC-Tvi-122448	Trichoderma virens	24.17	3.00e-12	67.40
IUUC-Tme-126925	Tuber melanosporum	23.29	6.00e-09	56.60
IUUC-Ttr-128761	Tursiops truncatus	81.44	0.00e+00	977.00
IUUC-Vda-129874	Verticillium dahliae	24.50	1.00e-13	71.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence