iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089369

Ensembl Protein ID

ENSOARP00000015803.1

UniProt Accession

W5PZB7; W5PZB7_SHEEP

Genbank Protein ID

ENSOARP00000015803

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01051101

Gene Name

DDX58

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000014731.1	ENSOART00000016036.1	ENSOARP00000015803.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	4.70e-45	152.2	1	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 1    tdeeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL..vqkegWfrefl 73
           ++ e+r+ l +++ +v k+Ld+t++l+ y++++++  +++ i+a++++kg+m+aa l+L++L  +q+egWfr+fl
   Q: 1    MTAEQRRNLHAFRGYVSKILDPTYILS-YMTPWFRDDVVQRIQAEKNNKGPMEAASLFLQVLleLQEEGWFRGFL 74
           5679***********************.*********************************************96 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MTAEQRRNLH AFRGYVSKIL DPTYILSYMT PWFRDDVVQR IQAEKNNKGP MEAASLFLQV 60
LLELQEEGWF RGFLDALHQA GYSGLCEAIE SWDFQKIEKL EEYRLLLKRL QPEFKTTINP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGGCCG AGCAGCGGCG GAATTTGCAC GCCTTCCGCG GCTATGTCAG CAAGATCCTG 60
GACCCTACCT ACATCCTGAG CTACATGACC CCCTGGTTTA GGGACGGTGA GTGGTTGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005923--C:bicellular tight junction
GO:0005829--C:cytosol
GO:0032587--C:ruffle membrane
GO:0005524--F:ATP binding
GO:0003690--F:double-stranded DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0009597--P:detection of virus
GO:0045087--P:innate immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0032725--P:positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0030334--P:regulation of cell migration
GO:0043330--P:response to exogenous dsRNA
GO:0039529--P:RIG-I signaling pathway

KEGG

oas:101107257

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001898	Ailuropoda melanoleuca	80.65	0.00e+00	1513.00
IUUC-Apl-003966	Anas platyrhynchos	53.82	0.00e+00	943.00
IUUC-Aca-004499	Anolis carolinensis	46.53	0.00e+00	805.00
IUUC-Ame-011950	Astyanax mexicanus	41.92	0.00e+00	690.00
IUUC-Bta-012489	Bos taurus	92.15	0.00e+00	1706.00
IUUC-Cel-018230	Caenorhabditis elegans	29.04	2.00e-68	254.00
IUUC-Cja-018716	Callithrix jacchus	78.71	0.00e+00	1461.00
IUUC-Cfa-020269	Canis familiaris	81.55	0.00e+00	1556.00
IUUC-Cpo-022507	Cavia porcellus	72.12	0.00e+00	1342.00
IUUC-Csa-024209	Chlorocebus sabaeus	78.82	0.00e+00	1472.00
IUUC-Cho-025104	Choloepus hoffmanni	72.46	0.00e+00	1162.00
IUUC-Cin-025792	Ciona intestinalis	33.19	2.00e-81	296.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	24.07	2.00e-19	92.40
IUUC-Dno-028954	Dasypus novemcinctus	75.62	0.00e+00	1388.00
IUUC-Eca-034039	Equus caballus	81.72	0.00e+00	1529.00
IUUC-Eeu-035009	Erinaceus europaeus	68.28	0.00e+00	915.00
IUUC-Fca-036169	Felis catus	82.96	0.00e+00	1580.00
IUUC-Fal-037579	Ficedula albicollis	53.58	0.00e+00	916.00
IUUC-Fso-038398	Fusarium solani	23.62	1.00e-18	89.40
IUUC-Ggo-045318	Gorilla gorilla	77.15	0.00e+00	1333.00
IUUC-Hsa-046671	Homo sapiens	79.35	0.00e+00	1451.00
IUUC-Itr-047996	Ictidomys tridecemlineatus	74.62	0.00e+00	1367.00
IUUC-Lch-050461	Latimeria chalumnae	51.87	0.00e+00	892.00
IUUC-Loc-052582	Lepisosteus oculatus	47.17	0.00e+00	823.00
IUUC-Laf-054324	Loxodonta africana	78.78	0.00e+00	1441.00
IUUC-Mcc-055390	Macaca mulatta	78.60	0.00e+00	1461.00
IUUC-Meu-056365	Macropus eugenii	63.29	1.00e-132	467.00
IUUC-Mor-057000	Magnaporthe oryzae	29.27	1.10e+00	29.30
IUUC-Mmr-061407	Microcebus murinus	78.39	0.00e+00	1494.00
IUUC-Mmu-063939	Mus musculus	73.33	0.00e+00	1361.00
IUUC-Mpu-066226	Mustela putorius furo	81.25	0.00e+00	1430.00
IUUC-Mlu-068092	Myotis lucifugus	79.66	0.00e+00	1466.00
IUUC-Nfi-068405	Neosartorya fischeri	24.87	2.00e-23	105.00
IUUC-Opr-070246	Ochotona princeps	64.89	0.00e+00	648.00
IUUC-Oan-072742	Ornithorhynchus anatinus	60.28	0.00e+00	979.00
IUUC-Ocu-073959	Oryctolagus cuniculus	73.23	0.00e+00	1372.00
IUUC-Oga-089173	Otolemur garnettii	77.18	0.00e+00	1431.00
IUUC-Ptr-091032	Pan troglodytes	79.35	0.00e+00	1451.00
IUUC-Pan-092383	Papio anubis	78.71	0.00e+00	1463.00
IUUC-Psi-093432	Pelodiscus sinensis	56.75	0.00e+00	1076.00
IUUC-Pma-094367	Petromyzon marinus	40.89	3.00e-112	399.00
IUUC-Pab-098416	Pongo abelii	79.20	0.00e+00	1356.00
IUUC-Pca-101006	Procavia capensis	80.25	0.00e+00	659.00
IUUC-Pva-102966	Pteropus vampyrus	81.53	0.00e+00	1527.00
IUUC-Pgr-103529	Puccinia graminis	26.10	8.00e-26	113.00
IUUC-Rno-105059	Rattus norvegicus	74.04	0.00e+00	883.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	26.06	3.00e-05	45.80
IUUC-Sit-109826	Setaria italica	30.34	2.30e+00	26.90
IUUC-Sar-113202	Sorex araneus	67.06	0.00e+00	1036.00
IUUC-Ssc-116120	Sus scrofa	81.85	0.00e+00	1527.00
IUUC-Tgu-117314	Taeniopygia guttata	52.01	0.00e+00	932.00
IUUC-Tsy-119453	Tarsius syrichta	78.10	0.00e+00	826.00
IUUC-Tre-122194	Trichoderma reesei	25.97	7.00e-16	80.10
IUUC-Ttr-128421	Tursiops truncatus	80.33	0.00e+00	1267.00
IUUC-Vpa-130602	Vicugna pacos	81.71	0.00e+00	1441.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence