iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000004710.3	ENSOCUT00000029633.1	ENSOCUP00000019472.1
ENSOCUG00000004710.3	ENSOCUT00000004712.3	ENSOCUP00000004071.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	3.40e-44	149.3	2	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 2    deeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL..vqkegWfrefl 73
           + e r+ l++++d+v+++Ld+t +l+ y+  +l e e+++i+a++++kg+m+aa l+Lk L  +++egWfr+fl
   Q: 2    TAEERRNLQAFSDYVKRILDPTHILS-YMNSWLGEDEVQYIQAEKNNKGPMEAASLFLKYLlqLKEEGWFRGFL 74
           567899********************.**********************************999********96 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MTAEERRNLQ AFSDYVKRIL DPTHILSYMN SWLGEDEVQY IQAEKNNKGP MEAASLFLKY 60
LLQLKEEGWF RGFLDALNNA GYSGLYEAIA NWNFQKIEKL EEYRALLKRL QPAFKDRIDP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCGCCG AGGAGCGGAG GAACCTGCAA GCCTTCAGCG ACTATGTCAA GAGGATTCTG 60
GACCCTACCC ACATCCTGAG CTACATGAAC TCCTGGCTTG GGGAGGGTGA GTGGATGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011545--DEAD/DEAH_box_helicase_dom
IPR011029--DEATH-like_dom
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00270--DEAD
PF00271--Helicase_C
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005923--C:bicellular tight junction
GO:0005829--C:cytosol
GO:0032587--C:ruffle membrane
GO:0005524--F:ATP binding
GO:0003690--F:double-stranded DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0009597--P:detection of virus
GO:0045087--P:innate immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0032725--P:positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0030334--P:regulation of cell migration
GO:0043330--P:response to exogenous dsRNA
GO:0039529--P:RIG-I signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001898	Ailuropoda melanoleuca	72.72	0.00e+00	1342.00
IUUC-Apl-003966	Anas platyrhynchos	51.57	0.00e+00	876.00
IUUC-Aca-004499	Anolis carolinensis	45.87	0.00e+00	774.00
IUUC-Ame-011950	Astyanax mexicanus	42.08	0.00e+00	682.00
IUUC-Bta-012489	Bos taurus	73.55	0.00e+00	1335.00
IUUC-Cel-018230	Caenorhabditis elegans	29.44	4.00e-72	266.00
IUUC-Cja-018716	Callithrix jacchus	75.92	0.00e+00	1418.00
IUUC-Cfa-020269	Canis familiaris	73.90	0.00e+00	1390.00
IUUC-Cpo-022507	Cavia porcellus	72.96	0.00e+00	1352.00
IUUC-Csa-024209	Chlorocebus sabaeus	76.35	0.00e+00	1421.00
IUUC-Cho-025104	Choloepus hoffmanni	68.40	0.00e+00	1082.00
IUUC-Cin-025792	Ciona intestinalis	31.68	1.00e-77	284.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	24.50	7.00e-23	103.00
IUUC-Dno-028954	Dasypus novemcinctus	71.57	0.00e+00	1289.00
IUUC-Eca-034039	Equus caballus	75.57	0.00e+00	1400.00
IUUC-Eeu-035009	Erinaceus europaeus	76.52	0.00e+00	812.00
IUUC-Fca-036169	Felis catus	75.24	0.00e+00	1397.00
IUUC-Fal-037579	Ficedula albicollis	52.40	0.00e+00	872.00
IUUC-Ggo-045318	Gorilla gorilla	74.58	0.00e+00	1290.00
IUUC-Hsa-046671	Homo sapiens	76.78	0.00e+00	1403.00
IUUC-Itr-047996	Ictidomys tridecemlineatus	73.02	0.00e+00	1341.00
IUUC-Lch-050461	Latimeria chalumnae	51.01	0.00e+00	853.00
IUUC-Loc-052582	Lepisosteus oculatus	47.00	0.00e+00	826.00
IUUC-Laf-054324	Loxodonta africana	72.59	0.00e+00	1315.00
IUUC-Mcc-055390	Macaca mulatta	75.59	0.00e+00	1401.00
IUUC-Meu-056365	Macropus eugenii	52.84	1.00e-175	610.00
IUUC-Mpo-057328	Magnaporthe poae	30.00	1.30e+00	28.90
IUUC-Mmr-061407	Microcebus murinus	75.35	0.00e+00	1434.00
IUUC-Mmu-063939	Mus musculus	72.00	0.00e+00	1326.00
IUUC-Mpu-066226	Mustela putorius furo	74.27	0.00e+00	1298.00
IUUC-Mlu-068092	Myotis lucifugus	73.31	0.00e+00	1328.00
IUUC-Nfi-068405	Neosartorya fischeri	25.00	5.00e-24	107.00
IUUC-Opr-070246	Ochotona princeps	74.90	0.00e+00	763.00
IUUC-Oan-072742	Ornithorhynchus anatinus	57.85	0.00e+00	929.00
IUUC-Obr-076109	Oryza brachyantha	52.17	1.40e+00	28.10
IUUC-Oga-089173	Otolemur garnettii	74.57	0.00e+00	1372.00
IUUC-Oar-089369	Ovis aries	73.23	0.00e+00	1298.00
IUUC-Ptr-091032	Pan troglodytes	76.78	0.00e+00	1403.00
IUUC-Pan-092383	Papio anubis	76.05	0.00e+00	1407.00
IUUC-Psi-093432	Pelodiscus sinensis	54.63	0.00e+00	1004.00
IUUC-Pma-094367	Petromyzon marinus	40.54	8.00e-110	390.00
IUUC-Pab-098416	Pongo abelii	77.05	0.00e+00	1320.00
IUUC-Pca-101006	Procavia capensis	76.20	2.00e-179	622.00
IUUC-Pva-102966	Pteropus vampyrus	73.49	0.00e+00	1355.00
IUUC-Rno-105059	Rattus norvegicus	73.52	0.00e+00	887.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	27.55	3.00e-03	38.90
IUUC-Sar-113202	Sorex araneus	65.54	0.00e+00	1009.00
IUUC-Ssc-116120	Sus scrofa	71.08	0.00e+00	1276.00
IUUC-Tgu-117314	Taeniopygia guttata	51.75	0.00e+00	900.00
IUUC-Tsy-119453	Tarsius syrichta	71.79	0.00e+00	758.00
IUUC-Tre-122194	Trichoderma reesei	26.42	2.00e-21	98.20
IUUC-Ttr-128421	Tursiops truncatus	69.64	0.00e+00	1077.00
IUUC-Vpa-130602	Vicugna pacos	72.10	0.00e+00	1254.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence