iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091032

Ensembl Protein ID

ENSPTRP00000035647.2

UniProt Accession

H2QX44; H2QX44_PANTR

Genbank Protein ID

JAA06341.1; JAA29916.1; JAA37097.1

Protein Name

DEAD (Asp-Glu-Ala-Asp) box polypeptide 58

Genbank Nucleotide ID

AACZ03066946; GABD01003184; GABE01007642

Gene Name

DDX58

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000020844.5	ENSPTRT00000038562.2	ENSPTRP00000035647.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	1.80e-59	198.2	1	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 1    tdeeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL..vqkegWfrefl 73
           +++e+r++l+++qd++rk+Ld+t++l+ y++++++eee+++i+a++++kg+m+aa+l+Lk+L  +q+egWfr+fl
   Q: 1    MTTEQRRSLQAFQDYIRKTLDPTYILS-YMAPWFREEEVQYIQAEKNNKGPMEAATLFLKFLleLQEEGWFRGFL 74
           689************************.*********************************************96 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MTTEQRRSLQ AFQDYIRKTL DPTYILSYMA PWFREEEVQY IQAEKNNKGP MEAATLFLKF 60
LLELQEEGWF RGFLDALDHA GYSGLYEAIE SWDFKKIEKL EEYRLLLKRL QPEFKTRIIP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAGTTATTAA AGTTCCTATG CAGCTCCGCC TCGCGTCCGG CATCATTTCC TCGGAAAATC 60
CCTGCTTTCC CCGCTCGCCA CGCCCTCCTC CTACCCGGCT TTAAAGCTGG TGAGGCACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011545--DEAD/DEAH_box_helicase_dom
IPR011029--DEATH-like_dom
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00270--DEAD
PF00271--Helicase_C
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005923--C:bicellular tight junction
GO:0005829--C:cytosol
GO:0032587--C:ruffle membrane
GO:0005524--F:ATP binding
GO:0003690--F:double-stranded DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0009597--P:detection of virus
GO:0045087--P:innate immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0032725--P:positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0030334--P:regulation of cell migration
GO:0043330--P:response to exogenous dsRNA
GO:0039529--P:RIG-I signaling pathway

KEGG

ptr:465035

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001898	Ailuropoda melanoleuca	79.70	0.00e+00	1493.00
IUUC-Apl-003966	Anas platyrhynchos	54.52	0.00e+00	927.00
IUUC-Aca-004499	Anolis carolinensis	46.94	0.00e+00	819.00
IUUC-Ame-011950	Astyanax mexicanus	44.17	0.00e+00	705.00
IUUC-Bta-012489	Bos taurus	80.11	0.00e+00	1460.00
IUUC-Cel-018230	Caenorhabditis elegans	29.08	5.00e-71	263.00
IUUC-Cja-018716	Callithrix jacchus	94.27	0.00e+00	1751.00
IUUC-Cfa-020269	Canis familiaris	81.70	0.00e+00	1544.00
IUUC-Cpo-022507	Cavia porcellus	77.23	0.00e+00	1448.00
IUUC-Csa-024209	Chlorocebus sabaeus	96.54	0.00e+00	1799.00
IUUC-Cho-025104	Choloepus hoffmanni	74.37	0.00e+00	1190.00
IUUC-Cin-025792	Ciona intestinalis	31.47	3.00e-79	289.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	25.42	7.00e-23	103.00
IUUC-Dno-028954	Dasypus novemcinctus	79.08	0.00e+00	1436.00
IUUC-Eca-034039	Equus caballus	82.16	0.00e+00	1541.00
IUUC-Eeu-035009	Erinaceus europaeus	70.02	0.00e+00	930.00
IUUC-Fca-036169	Felis catus	82.49	0.00e+00	1560.00
IUUC-Fal-037579	Ficedula albicollis	54.94	0.00e+00	932.00
IUUC-Fso-038398	Fusarium solani	26.64	5.00e-25	110.00
IUUC-Ggo-045318	Gorilla gorilla	95.85	0.00e+00	1656.00
IUUC-Hsa-046671	Homo sapiens	100.00	0.00e+00	1826.00
IUUC-Itr-047996	Ictidomys tridecemlineatus	79.52	0.00e+00	1459.00
IUUC-Lch-050461	Latimeria chalumnae	49.73	0.00e+00	877.00
IUUC-Loc-052582	Lepisosteus oculatus	48.61	0.00e+00	856.00
IUUC-Laf-054324	Loxodonta africana	79.34	0.00e+00	1453.00
IUUC-Mcc-055390	Macaca mulatta	95.78	0.00e+00	1780.00
IUUC-Meu-056365	Macropus eugenii	55.94	0.00e+00	632.00
IUUC-Mpo-057328	Magnaporthe poae	26.67	1.10e+00	29.30
IUUC-Mvi-060497	Microbotryum violaceum	24.57	1.00e-24	109.00
IUUC-Mmr-061407	Microcebus murinus	86.18	0.00e+00	1633.00
IUUC-Mmu-063939	Mus musculus	77.08	0.00e+00	1428.00
IUUC-Mpu-066226	Mustela putorius furo	79.88	0.00e+00	1409.00
IUUC-Mlu-068092	Myotis lucifugus	81.63	0.00e+00	1487.00
IUUC-Nfi-068405	Neosartorya fischeri	25.00	7.00e-27	116.00
IUUC-Opr-070246	Ochotona princeps	69.32	0.00e+00	694.00
IUUC-Oan-072742	Ornithorhynchus anatinus	61.81	0.00e+00	986.00
IUUC-Ocu-073959	Oryctolagus cuniculus	76.78	0.00e+00	1457.00
IUUC-Oga-089173	Otolemur garnettii	84.45	0.00e+00	1567.00
IUUC-Oar-089369	Ovis aries	79.35	0.00e+00	1420.00
IUUC-Pan-092383	Papio anubis	96.22	0.00e+00	1784.00
IUUC-Psi-093432	Pelodiscus sinensis	56.47	0.00e+00	1059.00
IUUC-Pma-094367	Petromyzon marinus	42.66	1.00e-117	416.00
IUUC-Pab-098416	Pongo abelii	98.74	0.00e+00	1698.00
IUUC-Pca-101006	Procavia capensis	77.72	0.00e+00	637.00
IUUC-Pva-102966	Pteropus vampyrus	83.33	0.00e+00	1548.00
IUUC-Pgr-103529	Puccinia graminis	27.39	8.00e-29	123.00
IUUC-Rno-105059	Rattus norvegicus	76.35	0.00e+00	913.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	27.55	9.00e-05	43.90
IUUC-Sar-113202	Sorex araneus	68.54	0.00e+00	1044.00
IUUC-Ssc-116120	Sus scrofa	78.71	0.00e+00	1423.00
IUUC-Tgu-117314	Taeniopygia guttata	53.01	0.00e+00	942.00
IUUC-Tsy-119453	Tarsius syrichta	84.84	0.00e+00	904.00
IUUC-Tre-122194	Trichoderma reesei	27.14	1.00e-20	95.90
IUUC-Ttr-128421	Tursiops truncatus	78.32	0.00e+00	1224.00
IUUC-Vpa-130602	Vicugna pacos	78.88	0.00e+00	1398.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence