iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ang-009773

Ensembl Protein ID

CAK43672

UniProt Accession

A2Q849; A2Q849_ASPNC

Genbank Protein ID

CAK43672.1

Protein Name

Aspergillus niger contig An01c0080, genomic contig

Genbank Nucleotide ID

AM269955

Gene Name

An01g03060

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
An01g03060	CAK43672	CAK43672

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.00e-88	295.5	853	1229

Active Site

Position(s)	Description	Evidence
1197	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 5    lkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp....................ehlklFeflGrll 78
           lk+ ++++f +     E+g+d gGvt+efl+ +++e ++++  l l++end++ l+pnp++  +                      + l+ +eflGr++
   Q: 853  LKEPIQITFIDkfnttEAGIDGGGVTKEFLTSVTSEAFKSTSDLNLFEENDQHLLYPNPAAVEQRRellrqlgfventaewnenvrDLLRRYEFLGRII 951
           6777888999889899*************************999999**************98766********************************* PP
   S: 79   gkalqdgrlldlplsksfyklllgk............klsledleevdpelykslkeikenaesdieelgldltfsvseei.....lgetkeeeLkpgG 160
           gk+l++g l+d++++++f+ +   +            + +l+dl+++d+ ly+ l ++k++   d+e+ +l++t++  ++i      + t++++Lk+ G
   Q: 952  GKCLYEGILVDVNFAPFFLLKWALTggtgsaqretayRANLNDLKDLDQGLYQGLLQLKNY-PGDVEDFSLNFTVT--DTIplpdgGNRTTTRDLKSHG 1047
           ******************988744445666767777779********************99.57999987777776..4444577699999999***** PP
   S: 161  enipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketky.....kggytedspaiqwFwevl 253
           ++ipVtn+N+  Y++ ++ yrl+ + + q++af +G+ ++i++++ls+F++ el++l++G+  +idv dl+++t y      g+ +e++p+++ Fwev+
   Q: 1048 SDIPVTNQNRLVYISYIARYRLQVQPALQTNAFLQGLGQIIQPSWLSMFNQTELQTLVSGDsGDIDVADLRRNTLYggvytIGDDKEEHPTVKLFWEVM 1146
           **************************************************************************9866556455579************ PP
   S: 254  eefsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           e++s+eer++ L+FvT+++r+Pl Gf  l+pr f ir+ +++++rlPs +TC+n+LkLP+Y++ +il+ekLlyA+++++gF+ls
   Q: 1147 EKMSNEERQKVLRFVTSTPRAPLLGFSHLNPR-FSIRDsSEDQERLPSTSTCVNLLKLPRYTNANILREKLLYAVNSGAGFDLS 1229
           ******************************99.8999946666**************************************985 PP

Organism

Aspergillus niger

Protein Sequence
(Fasta)

MFQSFTGNSR RPRQVNLGGR NTNPFAAYPS GRQNPHGAGP QNTLAIAQQE RLARQQERER 60
LTASRLVQRT WRGYRSRKIT RRTWRNEWDT TEKKQGKDHV PSFEILAQQP DVVLQPSLRY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTCCAGT CATTTACGGG GAACTCCCGC CGTCCACGGC AGGTTAACCT CGGGGGCCGC 60
AATACGAACC CTTTCGCCGC ATACCCCTCT GGTCGACAAA ATCCTCACGG CGCAGGCCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

ang:ANI_1_386014

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	34.42	6.00e-79	287.00
IUUC-Aml-001355	Ailuropoda melanoleuca	35.11	3.00e-84	305.00
IUUC-Atr-003017	Amborella trichopoda	33.22	3.00e-79	288.00
IUUC-Apl-003731	Anas platyrhynchos	36.11	1.00e-86	313.00
IUUC-Aca-005248	Anolis carolinensis	35.94	2.00e-86	312.00
IUUC-Aly-005768	Arabidopsis lyrata	37.15	4.00e-81	295.00
IUUC-Ath-007269	Arabidopsis thaliana	37.00	3.00e-81	295.00
IUUC-Ago-007748	Ashbya gossypii	37.95	1.00e-80	293.00
IUUC-Acl-008158	Aspergillus clavatus	81.77	0.00e+00	1831.00
IUUC-Afl-008398	Aspergillus flavus	82.91	0.00e+00	1876.00
IUUC-Afu-008937	Aspergillus fumigatus	82.26	0.00e+00	1871.00
IUUC-Ani-009252	Aspergillus nidulans	78.60	0.00e+00	1843.00
IUUC-Aor-009940	Aspergillus oryzae	82.99	0.00e+00	1878.00
IUUC-Ate-010395	Aspergillus terreus	82.20	0.00e+00	1814.00
IUUC-Ame-010769	Astyanax mexicanus	35.16	1.00e-59	223.00
IUUC-Bgr-012269	Blumeria graminis	61.61	1.00e-168	583.00
IUUC-Bta-012841	Bos taurus	36.00	1.00e-86	313.00
IUUC-Bci-013743	Botrytis cinerea	44.56	0.00e+00	929.00
IUUC-Bdi-014502	Brachypodium distachyon	38.41	2.00e-81	296.00
IUUC-Bol-015093	Brassica oleracea	36.98	1.00e-80	293.00
IUUC-Bra-016722	Brassica rapa	37.19	2.00e-81	296.00
IUUC-Cel-018447	Caenorhabditis elegans	33.27	4.00e-62	231.00
IUUC-Cja-019743	Callithrix jacchus	35.01	3.00e-83	301.00
IUUC-Cfa-021031	Canis familiaris	35.28	5.00e-85	307.00
IUUC-Cpo-022401	Cavia porcellus	35.28	3.00e-85	308.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	36.24	3.00e-68	250.00
IUUC-Csa-024107	Chlorocebus sabaeus	34.94	1.00e-83	303.00
IUUC-Cho-024750	Choloepus hoffmanni	41.91	8.00e-76	277.00
IUUC-Cin-025750	Ciona intestinalis	31.33	9.00e-63	233.00
IUUC-Csv-026016	Ciona savignyi	33.40	4.00e-71	261.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	41.37	0.00e+00	837.00
IUUC-Cne-026841	Cryptococcus neoformans	37.01	5.00e-90	324.00
IUUC-Cme-027265	Cyanidioschyzon merolae	39.79	2.00e-80	291.00
IUUC-Dre-028196	Danio rerio	36.49	6.00e-89	320.00
IUUC-Dno-029024	Dasypus novemcinctus	35.46	9.00e-86	310.00
IUUC-Dor-030938	Dipodomys ordii	34.89	4.00e-66	244.00
IUUC-Dse-031416	Dothistroma septosporum	44.65	0.00e+00	860.00
IUUC-Dme-031946	Drosophila melanogaster	37.32	1.00e-79	290.00
IUUC-Ete-033041	Echinops telfairi	30.99	6.00e-44	171.00
IUUC-Eca-033828	Equus caballus	35.11	1.00e-84	306.00
IUUC-Eeu-035201	Erinaceus europaeus	32.01	4.00e-45	174.00
IUUC-Fca-035907	Felis catus	35.28	1.00e-84	306.00
IUUC-Fal-037389	Ficedula albicollis	36.11	2.00e-86	312.00
IUUC-Fox-037788	Fusarium oxysporum	44.21	0.00e+00	704.00
IUUC-Fso-038088	Fusarium solani	43.02	0.00e+00	672.00
IUUC-Gmo-039412	Gadus morhua	32.72	3.00e-68	251.00
IUUC-Ggr-039941	Gaeumannomyces graminis	40.79	0.00e+00	743.00
IUUC-Gga-040310	Gallus gallus	35.94	5.00e-86	310.00
IUUC-Gac-042088	Gasterosteus aculeatus	30.41	4.00e-72	264.00
IUUC-Gma-042819	Glycine max	37.29	3.00e-73	268.00
IUUC-Ggo-045031	Gorilla gorilla	35.11	3.00e-84	305.00
IUUC-Hsa-045880	Homo sapiens	35.11	3.00e-84	305.00
IUUC-Hvu-047102	Hordeum vulgare	34.60	2.00e-78	285.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	34.66	2.00e-67	247.00
IUUC-Kpa-049307	Komagataella pastoris	34.76	2.00e-81	295.00
IUUC-Lch-050664	Latimeria chalumnae	30.13	2.00e-70	259.00
IUUC-Lpe-050755	Leersia perrieri	38.78	2.00e-79	289.00
IUUC-Loc-052218	Lepisosteus oculatus	36.66	2.00e-86	312.00
IUUC-Lma-053096	Leptosphaeria maculans	49.06	0.00e+00	1027.00
IUUC-Laf-053902	Loxodonta africana	30.16	6.00e-71	260.00
IUUC-Mcc-055127	Macaca mulatta	35.11	3.00e-84	305.00
IUUC-Meu-056527	Macropus eugenii	37.26	3.00e-55	208.00
IUUC-Mor-057021	Magnaporthe oryzae	41.19	0.00e+00	775.00
IUUC-Mpo-057570	Magnaporthe poae	46.78	0.00e+00	702.00
IUUC-Mtr-057671	Medicago truncatula	38.16	7.00e-82	297.00
IUUC-Mla-059124	Melampsora laricipopulina	42.03	9.00e-98	348.00
IUUC-Mga-059581	Meleagris gallopavo	35.94	5.00e-86	311.00
IUUC-Mvi-060445	Microbotryum violaceum	37.89	7.00e-119	420.00
IUUC-Mmr-061360	Microcebus murinus	35.11	6.00e-85	307.00
IUUC-Mdo-062194	Monodelphis domestica	36.11	1.00e-86	313.00
IUUC-Mmu-064189	Mus musculus	35.28	3.00e-84	305.00
IUUC-Mac-065275	Musa acuminata	37.39	9.00e-80	290.00
IUUC-Mpu-066439	Mustela putorius furo	35.28	1.00e-84	306.00
IUUC-Mlu-068228	Myotis lucifugus	35.28	6.00e-85	307.00
IUUC-Nfi-068280	Neosartorya fischeri	82.10	0.00e+00	1856.00
IUUC-Ncr-068869	Neurospora crassa	40.60	0.00e+00	733.00
IUUC-Nle-069687	Nomascus leucogenys	34.94	1.00e-83	303.00
IUUC-Opr-070554	Ochotona princeps	30.33	2.00e-70	259.00
IUUC-Ont-071836	Oreochromis niloticus	36.28	1.00e-85	309.00
IUUC-Oan-072800	Ornithorhynchus anatinus	35.94	2.00e-85	308.00
IUUC-Ocu-074587	Oryctolagus cuniculus	35.63	7.00e-86	310.00
IUUC-Oba-075213	Oryza barthii	38.45	3.00e-83	301.00
IUUC-Obr-076320	Oryza brachyantha	38.27	2.00e-83	301.00
IUUC-Ogl-077093	Oryza glaberrima	38.27	6.00e-84	304.00
IUUC-Ogu-078947	Oryza glumaepatula	36.76	1.00e-80	293.00
IUUC-Oin-080058	Oryza indica	38.65	1.00e-83	303.00
IUUC-Olo-080742	Oryza longistaminata	38.65	8.00e-84	304.00
IUUC-Ome-081741	Oryza meridionalis	37.42	6.00e-78	284.00
IUUC-Oni-082385	Oryza nivara	36.76	1.00e-80	293.00
IUUC-Opu-083529	Oryza punctata	38.85	4.00e-84	305.00
IUUC-Oru-085128	Oryza rufipogon	36.86	4.00e-74	271.00
IUUC-Osa-085557	Oryza sativa	38.65	3.00e-83	301.00
IUUC-Ola-087209	Oryzias latipes	36.49	7.00e-86	310.00
IUUC-Olu-087902	Ostreococcus lucimarinus	36.48	6.00e-68	249.00
IUUC-Oga-088776	Otolemur garnettii	35.28	2.00e-84	305.00
IUUC-Oar-089441	Ovis aries	36.00	1.00e-86	313.00
IUUC-Ptr-091273	Pan troglodytes	35.11	3.00e-84	305.00
IUUC-Pan-091981	Papio anubis	35.11	3.00e-84	305.00
IUUC-Psi-093251	Pelodiscus sinensis	29.64	1.00e-59	223.00
IUUC-Pma-094738	Petromyzon marinus	38.81	1.00e-80	293.00
IUUC-Pno-095132	Phaeosphaeria nodorum	52.73	0.00e+00	818.00
IUUC-Ppa-095544	Physcomitrella patens	38.24	3.00e-84	305.00
IUUC-Pfo-097511	Poecilia formosa	36.81	5.00e-86	311.00
IUUC-Pab-098634	Pongo abelii	33.22	6.00e-73	267.00
IUUC-Pop-099574	Populus trichocarpa	35.81	8.00e-69	253.00
IUUC-Pca-100987	Procavia capensis	41.40	2.00e-78	285.00
IUUC-Ppe-101281	Prunus persica	37.82	2.00e-80	292.00
IUUC-Pva-102887	Pteropus vampyrus	32.93	3.00e-69	255.00
IUUC-Pgr-103513	Puccinia graminis	38.45	4.00e-108	384.00
IUUC-Ptt-103967	Puccinia triticina	40.14	9.00e-96	343.00
IUUC-Pte-104105	Pyrenophora teres	50.04	0.00e+00	1022.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	50.12	0.00e+00	1007.00
IUUC-Rno-106028	Rattus norvegicus	28.41	3.00e-55	208.00
IUUC-Sce-106446	Saccharomyces cerevisiae	40.04	2.00e-81	295.00
IUUC-Sha-107108	Sarcophilus harrisii	33.28	5.00e-74	271.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	40.21	2.00e-91	328.00
IUUC-Spo-108097	Schizosaccharomyces pombe	38.43	3.00e-100	358.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	44.82	0.00e+00	920.00
IUUC-Smo-109537	Selaginella moellendorffii	39.54	4.00e-84	305.00
IUUC-Sit-109811	Setaria italica	38.64	1.00e-79	290.00
IUUC-Sly-111362	Solanum lycopersicum	36.65	8.00e-73	266.00
IUUC-Sar-113687	Sorex araneus	34.69	3.00e-42	165.00
IUUC-Sbi-114433	Sorghum bicolor	36.25	5.00e-84	304.00
IUUC-Sre-115038	Sporisorium reilianum	42.83	2.00e-96	345.00
IUUC-Ssc-116103	Sus scrofa	30.50	1.00e-70	259.00
IUUC-Tgu-116729	Taeniopygia guttata	36.28	2.00e-87	315.00
IUUC-Tru-118068	Takifugu rubripes	37.33	5.00e-88	317.00
IUUC-Tsy-118942	Tarsius syrichta	44.73	1.00e-59	223.00
IUUC-Tni-120732	Tetraodon nigroviridis	36.46	4.00e-81	295.00
IUUC-Tca-121770	Theobroma cacao	37.82	8.00e-82	297.00
IUUC-Tre-121892	Trichoderma reesei	41.10	0.00e+00	749.00
IUUC-Tvi-122354	Trichoderma virens	39.78	0.00e+00	771.00
IUUC-Tae-125229	Triticum aestivum	36.23	2.00e-77	282.00
IUUC-Tur-126086	Triticum urartu	34.42	8.00e-79	287.00
IUUC-Tme-127102	Tuber melanosporum	40.80	0.00e+00	749.00
IUUC-Ttr-129061	Tursiops truncatus	41.15	5.00e-78	284.00
IUUC-Uma-129343	Ustilago maydis	42.83	3.00e-99	355.00
IUUC-Vda-129748	Verticillium dahliae	45.40	0.00e+00	674.00
IUUC-Vvi-131524	Vitis vinifera	38.54	4.00e-80	291.00
IUUC-Xtr-132094	Xenopus tropicalis	35.76	2.00e-84	305.00
IUUC-Xma-133923	Xiphophorus maculatus	36.98	6.00e-86	310.00
IUUC-Yli-134496	Yarrowia lipolytica	36.94	1.00e-91	329.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence