iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-042474

UUCD1 version

UUC-GaA-00358

Ensembl Protein ID

ENSGACP00000009953.2

UniProt Accession

G3NX84; G3NX84_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000007464.2	ENSGACT00000009975.2	ENSGACP00000009953.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.20e-96	324.5	1609	1988

Active Site

Position(s)	Description	Evidence
1955	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 6    kkrlevefvgEegldlgGvtreflallskelqnpdlglf..........lysendketlqpnpdsglknp................. 65
           ++ le+++++E g++l G+t+ef+al+s+elq++dlgl+          + s++++             +                 
   Q: 1609 RAMLEIQYENEVGTGL-GPTLEFYALVSQELQRADLGLWrgeevtlanpKGSQEGT-------------Kymfsskglfavpfgrtt 1681
           56899***********.**********************44443333221111122.............123444566667799999 PP
   S: 66   ......ehlklFeflGrllgkalqdgrlldlplsksfyklllgk..klsledleevdpelykslkeikenaes.............. 130
                 +    F+flG+l++ka++d rlldlpl  +fyk +l++  ++s +dl ++dp ++ks++ +++   +              
   Q: 1682 kpahiaKIKMKFRFLGKLMAKAIMDFRLLDLPLGLPFYKWMLRHeaSISSHDLVNIDPGVAKSIQHLEDIIRQkkrleqdrsqtren 1768
           99***999999*********************************444666******************9983344555556666666 PP
   S: 131  .............dieelgldltfsvseei.....lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfne 199
                        ++e+            +     l+   + eLk gG++ pVt+ N+eeY +lvv ++l+eg+ +q+e+freGf++
   Q: 1769 lqqaleslnmngcSVED------------LgldftLPGFPNIELKKGGKDFPVTIYNLEEYLRLVVYWTLNEGVSRQFESFREGFES 1843
           74444444444334444............35555588999*********************************************** PP
   S: 200  viplellslFteeelellicGe..eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkp 284
           v+pl++l++F +eel++l+cG+  e++dv++l + ++ ++gyt+ds+a+++++evl++f++e+++ fLqFvTgs+rlP+gGf++l+p
   Q: 1844 VFPLHHLQYFYPEELDQLLCGSksETWDVKTLMECCRPDHGYTHDSRAVRFLFEVLSSFDAEQQRLFLQFVTGSPRLPVGGFRSLNP 1930
           *********************98889************************************************************* PP
   S: 285  rlfvirk.....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFels 336
            l+++rk     ++ dd lPs++TC+nyLkLP+Yss ei++ekLl+A +e+ ++F+ls
   Q: 1931 PLTIVRKtfestENPDDFLPSVMTCVNYLKLPDYSSIEIMREKLLIAAREGqQSFHLS 1988
           **********988888***************************************985 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MSNRPNSNPG GSLRRSQRNT AAAQPQDHTV TGRSGLTLSV ASFVLQDEPE AAGTSEQERP 60
GHQSKSEGTR GLKRSDAPDL ISTFGPTPAK KSKSVPPPKD NTSETKKVPA KSKKRPLAPE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCAACC GGCCTAATTC CAATCCAGGG GGGTCACTGC GCCGTTCACA GAGGAACACT 60
GCTGCGGCCC AGCCACAAGA CCACACAGTC ACAGGAAGGT GAGTCTTTAG TTTACATCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom
IPR004170--WWE-dom

PROSITE

PS50237--HECT
PS50918--WWE

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000750	Aegilops tauschii	38.52	1.00e-127	451.00
IUUC-Aml-001502	Ailuropoda melanoleuca	81.76	0.00e+00	3062.00
IUUC-Atr-002821	Amborella trichopoda	37.73	7.00e-120	426.00
IUUC-Apl-003531	Anas platyrhynchos	81.30	0.00e+00	3006.00
IUUC-Aly-005962	Arabidopsis lyrata	39.29	1.00e-117	418.00
IUUC-Ath-006636	Arabidopsis thaliana	38.86	3.00e-117	417.00
IUUC-Ago-007875	Ashbya gossypii	36.84	1.00e-82	301.00
IUUC-Acl-008242	Aspergillus clavatus	36.57	5.00e-118	420.00
IUUC-Afl-008736	Aspergillus flavus	40.55	5.00e-116	413.00
IUUC-Afu-008812	Aspergillus fumigatus	36.87	4.00e-120	426.00
IUUC-Ani-009407	Aspergillus nidulans	37.74	6.00e-114	406.00
IUUC-Ang-009763	Aspergillus niger	41.09	1.00e-110	395.00
IUUC-Aor-009941	Aspergillus oryzae	31.64	4.00e-119	423.00
IUUC-Ate-010459	Aspergillus terreus	38.30	2.00e-90	328.00
IUUC-Ame-011761	Astyanax mexicanus	91.05	0.00e+00	3084.00
IUUC-Bgr-012265	Blumeria graminis	36.01	9.00e-106	379.00
IUUC-Bta-013070	Bos taurus	84.17	0.00e+00	3112.00
IUUC-Bci-013890	Botrytis cinerea	40.28	4.00e-104	374.00
IUUC-Bdi-014046	Brachypodium distachyon	38.18	1.00e-124	441.00
IUUC-Bol-015942	Brassica oleracea	43.65	1.00e-115	412.00
IUUC-Bra-016849	Brassica rapa	43.65	4.00e-115	410.00
IUUC-Cja-019046	Callithrix jacchus	88.17	0.00e+00	3004.00
IUUC-Cfa-020521	Canis familiaris	81.12	0.00e+00	2962.00
IUUC-Cpo-021639	Cavia porcellus	78.66	0.00e+00	2977.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	39.88	5.00e-91	328.00
IUUC-Csa-023231	Chlorocebus sabaeus	86.01	0.00e+00	2992.00
IUUC-Cho-024380	Choloepus hoffmanni	75.54	0.00e+00	2756.00
IUUC-Cin-025482	Ciona intestinalis	50.65	3.00e-159	555.00
IUUC-Csv-026121	Ciona savignyi	48.91	0.00e+00	1554.00
IUUC-Cgl-026716	Colletotrichum gloeosporioides	35.68	5.00e-112	400.00
IUUC-Cne-026857	Cryptococcus neoformans	40.19	1.00e-94	342.00
IUUC-Cme-027226	Cyanidioschyzon merolae	35.71	4.00e-76	280.00
IUUC-Dre-028174	Danio rerio	90.91	0.00e+00	3130.00
IUUC-Dor-030939	Dipodomys ordii	78.87	0.00e+00	2532.00
IUUC-Dse-031444	Dothistroma septosporum	39.88	2.00e-109	391.00
IUUC-Dme-032162	Drosophila melanogaster	56.01	0.00e+00	667.00
IUUC-Ete-032345	Echinops telfairi	81.31	0.00e+00	2067.00
IUUC-Eca-033229	Equus caballus	81.37	0.00e+00	3029.00
IUUC-Eeu-035205	Erinaceus europaeus	75.49	0.00e+00	2649.00
IUUC-Fca-036444	Felis catus	80.01	0.00e+00	3044.00
IUUC-Fal-037131	Ficedula albicollis	80.68	0.00e+00	3065.00
IUUC-Fox-038035	Fusarium oxysporum	36.36	1.00e-110	393.00
IUUC-Fso-038320	Fusarium solani	36.46	1.00e-110	395.00
IUUC-Gmo-039497	Gadus morhua	94.08	0.00e+00	3460.00
IUUC-Ggr-040057	Gaeumannomyces graminis	35.16	2.00e-106	381.00
IUUC-Gga-041021	Gallus gallus	80.91	0.00e+00	3068.00
IUUC-Gma-043060	Glycine max	38.68	5.00e-122	433.00
IUUC-Ggo-044855	Gorilla gorilla	88.12	0.00e+00	3001.00
IUUC-Hsa-046147	Homo sapiens	88.63	0.00e+00	3023.00
IUUC-Hvu-047775	Hordeum vulgare	38.83	2.00e-126	447.00
IUUC-Itr-048131	Ictidomys tridecemlineatus	85.75	0.00e+00	2982.00
IUUC-Kpa-049098	Komagataella pastoris	37.70	2.00e-84	307.00
IUUC-Lch-049818	Latimeria chalumnae	84.70	0.00e+00	2885.00
IUUC-Lpe-051017	Leersia perrieri	37.68	4.00e-119	423.00
IUUC-Loc-051777	Lepisosteus oculatus	85.21	0.00e+00	3274.00
IUUC-Lma-052990	Leptosphaeria maculans	36.56	2.00e-114	407.00
IUUC-Laf-053727	Loxodonta africana	81.22	0.00e+00	3041.00
IUUC-Mcc-055799	Macaca mulatta	86.11	0.00e+00	2917.00
IUUC-Meu-056065	Macropus eugenii	82.87	0.00e+00	1907.00
IUUC-Mor-057054	Magnaporthe oryzae	39.35	5.00e-106	380.00
IUUC-Mpo-057417	Magnaporthe poae	39.73	8.00e-108	386.00
IUUC-Mtr-057849	Medicago truncatula	37.14	5.00e-113	403.00
IUUC-Mla-058870	Melampsora laricipopulina	42.28	4.00e-110	393.00
IUUC-Mga-059580	Meleagris gallopavo	81.31	0.00e+00	2642.00
IUUC-Mvi-060507	Microbotryum violaceum	41.52	2.00e-116	415.00
IUUC-Mmr-060816	Microcebus murinus	80.17	0.00e+00	3042.00
IUUC-Mdo-062866	Monodelphis domestica	79.20	0.00e+00	2833.00
IUUC-Mmu-063906	Mus musculus	81.67	0.00e+00	3066.00
IUUC-Mac-064675	Musa acuminata	38.03	4.00e-111	395.00
IUUC-Mpu-066199	Mustela putorius furo	79.01	0.00e+00	2942.00
IUUC-Mlu-067110	Myotis lucifugus	81.67	0.00e+00	3034.00
IUUC-Nfi-068482	Neosartorya fischeri	36.72	7.00e-119	422.00
IUUC-Ncr-068906	Neurospora crassa	39.84	1.00e-106	382.00
IUUC-Nle-069410	Nomascus leucogenys	86.92	0.00e+00	2991.00
IUUC-Opr-070401	Ochotona princeps	73.59	0.00e+00	2562.00
IUUC-Ont-072100	Oreochromis niloticus	92.29	0.00e+00	3498.00
IUUC-Oan-073121	Ornithorhynchus anatinus	80.31	0.00e+00	3089.00
IUUC-Ocu-074623	Oryctolagus cuniculus	85.82	0.00e+00	2912.00
IUUC-Oba-075380	Oryza barthii	32.00	7.00e-116	412.00
IUUC-Obr-076915	Oryza brachyantha	36.87	6.00e-119	422.00
IUUC-Ogl-077055	Oryza glaberrima	37.70	8.00e-119	422.00
IUUC-Ogu-078892	Oryza glumaepatula	31.67	2.00e-115	410.00
IUUC-Oin-079256	Oryza indica	37.52	1.00e-117	418.00
IUUC-Olo-080343	Oryza longistaminata	37.52	1.00e-117	418.00
IUUC-Ome-081422	Oryza meridionalis	37.52	1.00e-117	419.00
IUUC-Oni-083047	Oryza nivara	32.00	1.00e-116	414.00
IUUC-Opu-083641	Oryza punctata	35.62	6.00e-109	389.00
IUUC-Oru-084439	Oryza rufipogon	31.89	1.00e-115	411.00
IUUC-Osa-085972	Oryza sativa	37.75	3.00e-117	416.00
IUUC-Ola-087173	Oryzias latipes	91.69	0.00e+00	3424.00
IUUC-Olu-087871	Ostreococcus lucimarinus	37.64	1.00e-89	323.00
IUUC-Oga-087908	Otolemur garnettii	81.09	0.00e+00	3073.00
IUUC-Oar-090277	Ovis aries	81.23	0.00e+00	3072.00
IUUC-Ptr-091543	Pan troglodytes	88.63	0.00e+00	3026.00
IUUC-Pan-092243	Papio anubis	86.05	0.00e+00	2914.00
IUUC-Psi-093150	Pelodiscus sinensis	82.04	0.00e+00	3133.00
IUUC-Pno-094891	Phaeosphaeria nodorum	41.94	4.00e-116	413.00
IUUC-Ppa-095181	Physcomitrella patens	42.14	2.00e-106	380.00
IUUC-Pfo-096267	Poecilia formosa	90.50	0.00e+00	3395.00
IUUC-Pab-098072	Pongo abelii	87.21	0.00e+00	2998.00
IUUC-Pop-099190	Populus trichocarpa	37.57	3.00e-117	417.00
IUUC-Pca-100311	Procavia capensis	77.14	0.00e+00	2795.00
IUUC-Ppe-101284	Prunus persica	37.75	3.00e-117	417.00
IUUC-Pva-102215	Pteropus vampyrus	81.34	0.00e+00	1029.00
IUUC-Pgr-103694	Puccinia graminis	41.00	1.00e-107	385.00
IUUC-Ptt-103916	Puccinia triticina	35.91	1.00e-102	369.00
IUUC-Pte-104346	Pyrenophora teres	41.17	8.00e-115	409.00
IUUC-Pyt-104508	Pyrenophora triticirepentis	41.24	6.00e-115	409.00
IUUC-Rno-105315	Rattus norvegicus	85.99	0.00e+00	2888.00
IUUC-Sce-106273	Saccharomyces cerevisiae	34.90	7.00e-70	259.00
IUUC-Sha-106835	Sarcophilus harrisii	78.91	0.00e+00	3085.00
IUUC-Sja-107943	Schizosaccharomyces japonicus	39.11	3.00e-97	350.00
IUUC-Spo-108081	Schizosaccharomyces pombe	40.16	3.00e-98	354.00
IUUC-Ssl-108560	Sclerotinia sclerotiorum	40.28	3.00e-108	387.00
IUUC-Smo-108776	Selaginella moellendorffii	43.28	3.00e-112	400.00
IUUC-Sit-109757	Setaria italica	37.91	2.00e-122	434.00
IUUC-Sly-111469	Solanum lycopersicum	39.28	1.00e-122	435.00
IUUC-Stu-112896	Solanum tuberosum	38.07	1.00e-106	380.00
IUUC-Sar-113224	Sorex araneus	74.38	0.00e+00	1574.00
IUUC-Sbi-114313	Sorghum bicolor	38.55	3.00e-125	444.00
IUUC-Sre-114993	Sporisorium reilianum	33.81	3.00e-101	364.00
IUUC-Ssc-115535	Sus scrofa	78.87	0.00e+00	2948.00
IUUC-Tgu-117493	Taeniopygia guttata	80.55	0.00e+00	2389.00
IUUC-Tru-118669	Takifugu rubripes	90.18	0.00e+00	3376.00
IUUC-Tsy-119373	Tarsius syrichta	81.79	0.00e+00	1651.00
IUUC-Tni-120049	Tetraodon nigroviridis	84.22	0.00e+00	920.00
IUUC-Tca-121779	Theobroma cacao	38.91	3.00e-115	410.00
IUUC-Tre-122195	Trichoderma reesei	36.40	7.00e-107	382.00
IUUC-Tvi-122650	Trichoderma virens	36.23	5.00e-108	386.00
IUUC-Tae-123580	Triticum aestivum	38.58	8.00e-126	444.00
IUUC-Tur-126295	Triticum urartu	38.69	4.00e-127	450.00
IUUC-Tme-126964	Tuber melanosporum	40.94	5.00e-109	390.00
IUUC-Tbe-128149	Tupaia belangeri	74.76	0.00e+00	1130.00
IUUC-Ttr-128165	Tursiops truncatus	84.58	0.00e+00	2779.00
IUUC-Uma-129365	Ustilago maydis	35.59	9.00e-89	323.00
IUUC-Vda-129725	Verticillium dahliae	41.35	2.00e-109	391.00
IUUC-Vpa-130678	Vicugna pacos	86.87	0.00e+00	2427.00
IUUC-Vvi-131147	Vitis vinifera	39.40	5.00e-123	436.00
IUUC-Xtr-132636	Xenopus tropicalis	80.31	0.00e+00	2998.00
IUUC-Xma-133458	Xiphophorus maculatus	90.60	0.00e+00	3449.00
IUUC-Yli-134481	Yarrowia lipolytica	39.56	3.00e-99	357.00
IUUC-Zma-135782	Zea mays	38.03	1.00e-117	418.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence